دانلود مقالات ISI درباره Pparα + ترجمه فارسی

Anti-inflammatory effect of lactobacilli bacteria on HepG2 cells is through cross-regulation of TLR4 and NOD2 signalling

Keywords: Cell injury; Lactobacilli bacteria; LPS; Mechanism of action; PPARα; Suppressor of cytokine signalling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Tumour necrosis factor alpha down-regulates the expression of peroxisome proliferator activated receptor alpha (PPARα) in human hepatocarcinoma HepG2 cells by activation of NF-κB pathway

Keywords: Inflammation; Acute phase response; PPARα; TNF-α; NF-κB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21

Keywords: LH21; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole; Rimonabant; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; PPARα; perox

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA

Keywords: a2m; alpha-2-macroglobulin; APR; acute-phase response; cdo1; cysteine dioxygenase type I; CEH; chicken embryonic hepatocytes; cpb2; carboxypeptidase B2; DE; differentially expressed; DMSO; dimethyl sulfoxide; f2; thrombin (coagulation factor II); FDR; fal

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

Keywords: StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes

Keywords: Ad; adiponectin; NEB; negative energy balance; AdipoR1; adiponectin receptor 1; AdipoR2; adiponectin receptor 2; AMPK; AMP-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; SREBP-1c; sterol regulatory element-binding protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Rokumi-jio-gan-containing prescriptions regulate oxidative stress through improving dyslipidemia in a subtotal nephrectomized rat model

Keywords: AGE; advanced glycation endproduct; Cr; creatinine; Ccr; creatinine clearance; COX-2; cyclooxygenase-2; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; GSH; reduced glutathione; GSSG; oxidized

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes

Keywords: Resistin; SIRT1; Hepatocytes; PPARα; PGC-1α; Senescence-associated β-galactosidase activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Punctum on two different transcription factors regulated by PGC-1α: Nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2

Keywords: γGCS; gamma-glutamylcysteine synthetase; ARE; antioxidant responsive element; BAT; brown adipose tissue; CNC; Cap 'n' collar; COX; cytochrome c oxidase; CR; calorie restriction; CREB; cAMP response element-binding protein; ERRs; Estrogen-related rece

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2013 سفارش ترجمه

Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age

Keywords: CMT; Charcot Marie Tooth disease; Cra; Cramping allele of the Dync1h1 gene (p.Y1055C mutation); IPGTT; intra-peritoneal glucose tolerance test; LPL; lipoprotein lipase; MEF; mouse embryonic fibroblast; MFN; mitofusin; PPARα; peroxisome proliferation acti

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2013 سفارش ترجمه

Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells

Keywords: ACOX-1; acyl-CoA oxidase 1; ABCA1; ATP binding cassette transporter A1; ABCG5/8; ATP binding cassette transporter G5/8; CVD; cardiovascular disease; CPT-1α; carnitine palmitoyltransferase 1α; FAS; fatty acid synthase; HMGR; 3-hydroxy-3-methylglutaryl co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Bidirectional fluorescence properties of pyrene-based peroxisome proliferator-activated receptor (PPAR) α/δ dual agonist

Keywords: Peroxisome proliferator-activated receptor; PPARδ; PPARα; Fluorescent PPARα/δ co-agonist; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Oral bezafibrate induces daily torpor and FGF21 in mice in a PPAR alpha dependent manner

Keywords: Core body temperature; Torpor; Hibernation; PPARα; FGF21;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation

Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AMPK; AMP-activated protein kinase; CD36; fatty acid translocase/CD36; CPT1; carnitine palmitoyltransferase 1; FA; fatty acids; NEFA; non-esterified FA; FATP1; fatty acid transp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticlePPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats

Keywords: PPARα; peroxisome proliferator-activated receptor α; CCl4; carbon tetrachloride; MAP; mean arterial pressure; PP; portal pressure; PBF; portal blood flow; Mtx; methoxamine; α-SMA; alfa smooth muscle actin; NO; nitric oxide; TAA; thioacetamide; TG; trig

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

PPARα and PPARγ regulate the nucleoside transporter hENT1

Keywords: Equilibrative nucleoside transporter; PPARα; Chemotherapeutic drugs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration

Keywords: Oleoylethanolamide; N-acylethanolamines; Endocannabinoids; CB1; PPARα; Fast; Satiety;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Improvement of the energy supply and contractile function in normal and ischemic rat hearts by dietary orotic acid

Keywords: Cardiac metabolism; Isolated perfused heart; PPARα; Fatty acid oxidation; Glycolytic flux; Lipoprotein lipase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Allelic and phenotypic spectrum of plasma triglycerides

Keywords: ABL; abetalipoproteinemia; ANGPTL3; angiopoietin-like 3; ANGPTL4; angiopoietin-like 4; APOA4; apolipoprotein A-IV; APOA5; apolipoprotein A-V; APOB; apolipoprotein B; APOC2; apolipoprotein C-II; APOC3; apolipoprotein C-III; APOE; apolipoprotein E; CAD; cor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters

Keywords: PCSK9; LDLR; SREBP; HNF1α; PPARα; LXR; LDL-cholesterol; Fasting; Golden Syrian hamsters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet

Keywords: AA; arachidonic acid; ACOX1; acyl-coenzyme A oxidase 1, palmitoyl; CPT2; carnitine palmitoyl transferase 2; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HMG-CoA synthase (HMGCS); 3-hydroxy-3-methylglutaryl-coenzyme A synthase; hTNFα; human tumo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Adiponectin promotes hyaluronan synthesis along with increases in hyaluronan synthase 2 transcripts through an AMP-activated protein kinase/peroxisome proliferator-activated receptor-α-dependent pathway in human dermal fibroblasts

Keywords: HAS2; hyaluronan synthase 2; AMPK; AMP-activated protein kinase; AICAR; 5-aminoimidazole-4-carboxamide-1β-ribofuranoside; PPARα; peroxisome proliferator-activated receptor-α; AdipoR; adiponectin receptor; FBS; fetal bovine serum; MEM; modified Eagle'

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes

Keywords: PPARα; Adipocyte; Insulin sensitivity; Fatty acid oxidation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of TNFα-induced adhesion molecule expression by (Z)-(S)-9-octadecenamide, N-(2-hydroxyethyl,1-methyl)

Keywords: OPA; PPARα; HUVEC; Adhesion molecules; Inflammation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Soluble FGFR4 extracellular domain inhibits FGF19-induced activation of FGFR4 signaling and prevents nonalcoholic fatty liver disease

Keywords: FGFR4; fibroblast growth factor receptor 4; NAFLD; nonalcoholic fatty liver disease; FGFR4-ECD; FGFR4 extracellular domain; PPARα; peroxisome proliferator-activated receptor α; FGFs; fibroblast growth factors; HCC; hepatocellular carcinoma cell; ALT; al

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress

Keywords: LPS; lipopolysaccharide; TLR; Toll-like receptors; TNFα; tumor necrosis factor-α; NF-κB; nuclear factor-κB; MAPK; mitogen activated protein kinase; STAT; signal transducers and activators of transcription; ALT; alanine aminotransferase; WT; wild-type;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Sensitive bioassay for detection of PPARα potentially hazardous ligands with gold nanoparticle probe

Keywords: GNP; gold nanoparticle; LC-MS; liquid chromatography/tandem mass spectrometry; PFOA; perfluorooctanoic acid; PFOS; perfluorooctane sulfonate; MEHP; mono-(2-ethylhexyl) phthalate; PPARα; peroxisome proliferator-activated receptor α; PPRE; PPARα-respon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis, molecular modeling studies and biological evaluation of fluorine substituted analogs of GW 501516

Keywords: GW 501516; Agonist; Fluorine; PPARα; PPARδ;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds

Keywords: CM-H2DCFA; 5-(and 6-) chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate; DAB; 3,3′-diaminobenzidine; DCF; 2′,7′-dichlorofluorescein; DEHP; di(2-ethylhexyl)phthalate; DR5; death receptor 5; FBS; fetal bovine serum; FCS; fetal calf serum; GP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract

Keywords: AA-5-HT; arachidonoyl-serotonin; AEA; arachidonoyl ethanolamide; AMC; fluorophore7-amino-4-methylcoumarin; CB1; cannabinoid receptors 1; CID; collision-induced dissociation; DHA; docosahexaenoic acid; DHA-5-HT; docosahexaenoyl-serotonin; EPA-5-HT; eicosap

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes

Keywords: AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; BCH; 2-aminobicyclo[2.2.1]heptan-2-carboxylic acid; CPT-1; carnitine palmitoyl transferase-1; FFA; free fatty acid; FAO; fatty acid oxidation; GLUT4; glucose

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleNaringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism

Keywords: HCV; Naringenin; Lipid metabolism; PPARα;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice

Keywords: DEHP; PPARα; Offspring; TG; MTP; β-Oxidation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Keywords: 4E-BP1; 4E binding protein 1; 5′UTR; 5′ untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5′-AMP-activated protein kinase; AMPK α1−/−; AMPK α1 subunit knockout; AMPKα1−/−α2−/−; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Hepatosteatosis in peroxisome deficient liver despite increased β-oxidation capacity and impaired lipogenesis

Keywords: Hepatosteatosis; Fatty acid oxidation; Fatty acid uptake; PPARα; ACC; acetyl-CoA carboxylase; ACLY; ATP citrate lyase; Acox1; acyl-CoA oxidase; Adfp; adipose differentiation related protein; Apo; apolipoprotein; Cpt; carnitine palmitoyltransferase; DHA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

NADPH oxidase and eNOS control cardiomyogenesis in mouse embryonic stem cells on ascorbic acid treatment

Keywords: AA; ascorbic acid; DAF-2DA; 4-amino-5-methylamino-2′,7′-difluorofluorescein diacetate; DHE; dihydroethidium; DMSO; dimethyl sulfoxide; DPI; diphenylene iodonium; DTT; dithiotreitol; ES cells; embryonic stem cells; H2DCF-DA; 2´,7´-dichlorodihydrofluo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Current and future use of genomics data in toxicology: Opportunities and challenges for regulatory applications

Keywords: BMD; benchmark dose; CAR; constitutive activated receptor; CFSAN; FDA center for food safety and applied nutrition; CTD; Comparative Toxicogenomics Database; DBP; dibutyl phthalate; eGOn; explore gene ontology; EPA; Environmental Protection Agency; EST; e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Toxicological evaluation of ammonium 4,8-dioxa-3H-perfluorononanoate, a new emulsifier to replace ammonium perfluorooctanoate in fluoropolymer manufacturing

Keywords: Ammonium 4,8-dioxa-3H-perfluorononanoate; ADONA; Genotoxicity; NOAEL; Developmental toxicity; Subchronic toxicity; Ammonium perfluorooctanoate; APFO; PPARα;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of fenofibrate therapy and ABCA1 polymorphisms on high-density lipoprotein subclasses in the Genetics of Lipid Lowering Drugs and Diet Network

Keywords: HDL-C; HDL-cholesterol; PPARα; peroxisome proliferator-activated receptor alpha; ABCA1; ATP-binding cassette transporter 1; CAD; coronary artery disease; MESA; Multi-Ethnic Study of Atherosclerosis; VA-HIT; Veterans Affairs High-Density Lipoprotein Inter

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of PPARα by bezafibrate negatively affects de novo synthesis of sphingolipids in regenerating rat liver

Keywords: Serine palmitoyltransferase; Liver regeneration; Partial hepatectomy; High-fat diet; PPARα; Bezafibrate;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of TNFα on activities of different promoters of human apolipoprotein A-I gene

Keywords: HDLs; high density lipoproteins; ApoA-I; apolipoprotein A-I; TNFα; tumour necrosis factor α; TSP; transcription start point; CP; canonical apoA-I promoter; PAP; proximal alternative promoter; DAP; distal alternative promoter; HE; hepatic enhancer; HDLs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleUnexpected effects of fasting on murine lipid homeostasis - Transcriptomic and lipid profiling

Keywords: PPARα; peroxisome proliferator-activated receptor α; TG; triglyceride; PL; phospholipids; FFA; free fatty acid; VLDL; very low density lipoprotein; BS; bile salts; TICE; trans-intestinal cholesterol excretion; HA; haematoxyline azophloxine; PNCA; prolif

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

PPARα stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner

Keywords: PPARα; Hypertension; Aortic coarctation; Oxidative stress; Nitric oxide; Superoxide dismutase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Heme Oxygenase-1 Protects Against Steatohepatitis in Both Cultured Hepatocytes and Mice

Keywords: ACO; acyl-CoA oxidase; Ad-HO-1; adenovirus vector that expressed HO-1; ALT; alanine aminotransferase; cDNA; complementary DNA; CO; carbon monoxide; Cryab; crystallin α-B; Cyp; cytochrome P450; Fancc; fanconi anemia C; Gpx; glutathione peroxidase; HO-1; h

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

The PPARα Agonist Fenofibrate Preserves Hippocampal Neurogenesis and Inhibits Microglial Activation After Whole-Brain Irradiation

Keywords: Radiation; PPARα; Microglia; Neurogenesis; Inflammation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice

Keywords: Pten KO; Pten-deficient; EPA; eicosapentaenoic acid; ROS; reactive oxygen species; HCC; hepatocellular carcinoma; NASH; non-alcoholic steatohepatitis; NAFLD; non-alcoholic fatty liver disease; TG; triglyceride; PUFA; polyunsaturated fatty acid; SREBP-1; s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Organic cation/carnitine transporter OCTN3 is present in astrocytes and is up-regulated by peroxisome proliferators-activator receptor agonist

Keywords: BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; OCTN; organic cation transporter novel f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14,643

Keywords: Peroxisomal 3-ketoacyl-CoA thiolase B; PPARα; Mono-unsaturated fatty acids n-7 and n-9; Stearoyl-CoA desaturase-1; Wy14,643; ThB; peroxisomal 3-ketoacyl-CoA thiolase B; ThA; peroxisomal 3-ketoacyl-CoA thiolase A; ACOX-I; peroxisomal acyl-CoA oxidase-I; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of peroxisome proliferator-activated receptor-α expression during lung inflammation

Keywords: PPARα; Inflammation; Acute lung injury; Asthma; Tumor necrosis factor-α; Lipopolysaccharide; Fenofibrate; Dexamethasone; Lung; Mouse;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه