دانلود مقالات ISI درباره Pparα + ترجمه فارسی

LIGHT is increased in patients with coronary disease and regulates inflammatory response and lipid metabolism in oxLDL-induced THP-1 macrophages

Keywords: LIGHT; Inflammation; Hyperlipidemia; Atherosclerosis; NF-κB; TNSF14/LIGHT; tumor necrosis factor superfamily member 14; oxLDL; oxidized low-density lipoproteins; NF-κB; nuclear factor-kappa B; LDLs; low-density lipoproteins; TNFSF; tumor necrosis factor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The peroxisome proliferator-activated receptor alpha agonist fenofibrate attenuates alcohol self-administration in rats

Keywords: Addiction; Alcohol; Ethanol; Self-administration; Progressive ratio; PPARα; Peroxisome proliferator-activated receptors; Ethanol reinforcement; Drug seeking; Rats;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of the chlorogenic acid as multitarget agent: Insulin-secretagogue and PPAR α/γ dual agonist

Keywords: Chlorogenic acid; Multitarget pharmaceuticals; Insulin secretagogue; Insulin sensitizers; PPARγ; PPARα;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A secretome analysis reveals that PPARα is upregulated by fractionated-dose γ-irradiation in three-dimensional keratinocyte cultures

Keywords: Keratinocyte; γ-irradiation; Three-dimensional culture; Microarray; Secretome; PPARα;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Over-expression of PPARα in obese mice adipose tissue improves insulin sensitivity

Keywords: PPARα; Adipose tissue; Insulin sensitivity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cornelian cherry consumption increases the l-arginine/ADMA ratio, lowers ADMA and SDMA levels in the plasma, and enhances the aorta glutathione level in rabbits fed a high-cholesterol diet

Keywords: ADMA; asymmetric dimethylarginine; DDAH; dimethylarginine dimethylaminohydrolase; MDA; malondialdehyde; ELISA; enzyme-linked immunosorbent assay; eNOS; endothelial nitric oxide synthase; HPLC; high-performance liquid chromatography; PPARα; peroxisome pro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The PPARα activator fenofibrate inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

Keywords: Fenofibrate; PPARα; Voltage-dependent K+ channel; Coronary arterial smooth muscle cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

16-Dehydropregnenolone lowers serum cholesterol by up-regulation of CYP7A1 in hyperlipidemic male hamsters

Keywords: 16-Dehydropregnenolone; Cholesterol; Bile acid; CYP7A1; LXRα; PPARα; HepG2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice

Keywords: PPARα; SPPARMα; HDL cholesterol; Cholesterol absorption;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Red paprika (Capsicum annuum L.) and its main carotenoid capsanthin ameliorate impaired lipid metabolism in the liver and adipose tissue of high-fat diet-induced obese mice

Keywords: NAFLD; non-alcoholic fatty liver disease; WAT; white adipose tissue; ND; normal diet; HD; high-fat diet; RP; red paprika-supplemented diet; CS; capsanthin-supplemented diet; TG; triacylglycerol; TC; total cholesterol; HDL; high-density lipoprotein; NEFA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Cross-interference of two model peroxisome proliferators in peroxisomal and estrogenic pathways in brown trout hepatocytes

Keywords: PPARα; Estrogens; Peroxisomes; Hepatocytes; Brown trout;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between NR1I2 polymorphisms and inflammatory bowel disease risk: A systematic review and meta-analysis

Keywords: NR1I2; Homo sapiens nuclear receptor subfamily 1 group I member 2; IBD; inflammatory bowel diseases; UC; Ulcerative Colitis; CD; Crohn's Disease; OR; odd radio; CI; confidence interval; PPARα; peroxisome proliferator-activated receptor alpha; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation

Keywords: Brown adipocyte differentiation; Brown fat; Thermogenesis; Blnc1; lncRNA; EBF2; BAT; brown adipose tissue; RACE; rapid amplification of cDNA ends; Ucp1; uncoupling protein 1; Elovl3; elongation of very long chain fatty acids like 3; Cox7a1; cytochrome c o

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic proteins via PPARα down-regulation

Keywords: CYP2E1; cytochrome P450 2E1; ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophin-3; DMSO; dimethyl sulfoxide; ChIP; chroma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro and in vivo pharmacology of NXT629, a novel and selective PPARα antagonist

Keywords: PPARα; PPARα antagonism; Fatty acid oxidation; Cancer;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro

Keywords: Wogonin; NAFLD; Oxidative stress; PPARα; AdipoR2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration

Keywords: AMD; Age Related Macular Degeneration; ANOVA; Analysis of Variance; ARBP; 60S Acidic Ribosomal Protein P0; BEST1; Bestrophin; CAT; Catalase; cDNA; Complementary DNA; CMST; Cell Mito Stress Test; CRABP; Cellular Retinoic Acid Binding Protein; CRALBP; Cellu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The potential of natural products for targeting PPARα

Keywords: PPARα; Natural product; Mechanism of action; Dyslipidemia; Metabolic syndrome;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice

Keywords: ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock

Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Control of adipogenesis by oxylipins, GPCRs and PPARs

Keywords: Eicosanoid; Prostanoid; Adipocyte; PPARα; PPARβ/δ; PPARγ; PUFA; polyunsaturated fatty acids; LA; linoleic acid; ARA; arachidonic acid; LNA; α-linolenic acid; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; DGLA; dihomo-γ-linolenic acid; COX;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of gomisin N against hepatic steatosis through AMPK activation

Keywords: Gomisin N; Nonalcoholic fatty liver disease; Lipogenesis; AMP-activated protein kinase; Sterol regulatory element-binding protein 1c; High-fat diet; ACC; Acetyl-CoA carboxylase; AMPK; Adenosine monophosphate (AMP)-activated protein kinase; CPT 1; Carnitin

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs

Keywords: Ophiopogonin D; CYP2J2; PPARα; Angiotensin II; HUVECs;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis

Keywords: CYP2A6; Cytochrome P450 2A6; CYP2E1; Cytochrome P450 2E1; Cyp2e1−/− mice; Cyp2e1 knockout mice; CYP2A5; Cytochrome P450 2A5; Cyp2a5−/− mice; Cyp2a5 knockout mice; NRF2; nuclear factor-erythroid 2-related factor 2; Nrf2−/− mice; Nrf2 knockout m

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Dihydrosterculic acid from cottonseed oil suppresses desaturase activity and improves liver metabolomic profiles of high-fat-fed mice

Keywords: Fatty acid oxidation; Desaturation; Metabolomics; Bioactive lipids; Nuclear magnetic resonance (NMR) spectroscopy; 18:2; linoleic acid-rich diet; 18:2n6; linoleic acid; CHO; carbohydrate; CPFA; cyclopropyl fatty acid; CSO; cottonseed oil; DHSA; dihydros

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation

Keywords: ABHD4; α/β-hydrolase domain 4; AEA; N-arachidonoylethanolamine; DHEA; N-docosahexaenoylethanolamine; DTEA; N-docosatetraenoylethanolamine; FAAH; fatty acid amide hydrolase; GDE1; glycerophosphodiester phosphodiesterase 1; NAAA; N-acylethanolamine-hydrol

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Pigment epithelium-derived factor improves TNFα-induced hepatic steatosis in grass carp (Ctenopharyngodon idella)

Keywords: Grass carp (Ctenopharyngodon idella); PEDF; TNFα; Hepatic steatosis; PPARα;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

PPARα activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway

Keywords: MHY908; FoxO1; PPARα; Insulin; Aging;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of dietary fatty acid composition on growth, fatty acids composition and hepatic lipid metabolism in juvenile turbot (Scophthalmus maximus L.) fed diets with required n3 LC-PUFAs

Keywords: LC-PUFA; Long-chain polyunsaturated fatty acid; HDL-c/LDL-c; Ratio of high- to low-density lipoprotein cholesterol; LPL; Lipoprotein lipase; G6PD; Glucose-6-phosphate dehydrogenase; ME; Malic enzyme; ApoB-100; Apolipoprotein B-100; PPARα; Peroxisome prol

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

Keywords: Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Saponins from stems and leaves of Panax ginseng prevent obesity via regulating thermogenesis, lipogenesis and lipolysis in high-fat diet-induced obese C57BL/6 mice

Keywords: Anti-obesity; Saponins; Panax ginseng; C57BL/6 mice; Haematoxylin and eosin; RT-PCR; aP2; adipocyte fatty acid binding protein 2; ATGL; adipose triglyceride lipase; CD36; cluster of differentiation 36; CPT-1; carnitine O-palmitoyltransferase 1; FFA; free

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Acot1 is a sensitive indicator for PPARα activation after perfluorooctanoic acid exposure in primary hepatocytes of Sprague-Dawley rats

Keywords: DCF; 2′,7′-dichlorofluorescein; Acot; acyl-CoA thioesterase; Cyp4a1; cytochrome P450, family 4, subfamily a, polypeptide 1; DEGs; differentially expressed genes; Ech1; enoyl CoA hydratase 1, peroxisomal; GO; gene ontology; Hadha; hydroxyacyl-CoA dehyd

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of growth, antioxidant capacity, fatty acid profiles, hematological characteristics and expression of lipid related genes by different dietary n-3 highly unsaturated fatty acids in juvenile black seabream (Acanthopagrus schlegelii)

Keywords: accα; acetyl-CoA carboxylase alpha; atgl; adipose triglyceride lipase; cpt1a; carnitine palmitoyltransferase 1A; elovl5; elongase 5; fas; fatty acid synthase; g6pd; glucose 6-phosphate dehydrogenase; hsl; hormone-sensitive lipase; lpl; lipoprotein lipase

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal

Keywords: CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity

Keywords: ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CCK8; Cell Counting Kit-8; DAB; 3,3′-diaminobenzidine; DAPI; 4′, 6-diamidino-2-phenylindole; DCFH-DA; 2′,7′-Dichlorofluorescein diacetate; DHE; dihydroethidium; D

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling

Keywords: AhR; aryl hydrocarbon receptor; CAR; constitutive activated receptor; DEHP; di-(2-ethylhexyl)phthalate; ERα; estrogen receptor α; ERE; estrogen response element; GH; growth hormone; LXR; liver X receptor; Nrf2; nuclear factor erythroid-2-related factor

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular aspects of lipid metabolism, digestibility and antioxidant status of Atlantic bluefin tuna (T. thynnus L.) larvae during first feeding

Keywords: ABT; Atlantic bluefin tuna; aco; acyl coA oxidase; alp; alkaline phosphatase; amy; amylase; anpep; amino peptidase; ARA; arachidonic acid (20:4n-6); bal1; bile salt activated lipase 1; bal2; bile salt activated lipase 2; C; free cholesterol; cat; catalase

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

PARP1-mediated PPARα poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease

Keywords: Non-alcoholic fatty liver disease; Poly(ADP-ribose) polymerase 1; PPARα; Transcriptional regulation; High fat diet;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Does bilirubin prevent hepatic steatosis through activation of the PPARα nuclear receptor?

Keywords: Heme oxygenase; Bilirubin; Biliverdin; NAFLD; NASH; Non-alcoholic fatty liver disease; PPAR; PPARα; SPPARM; Nuclear receptors;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Invited perspectivePPARα in lysosomal biogenesis: A perspective

Keywords: Lysosomal biogenesis; TFEB; Lipid metabolism; Fibrate drugs; PPARα;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction

Keywords: Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Interleukin 6 modulates PPARα and PGC-1α and is involved in high-fat diet induced cardiac lipotoxicity in mouse

Keywords: PPARα; PGC-1α; Heart; Mouse; Lipotoxicity; High fat diet;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Narrow time window of metabolic changes associated with transition to overt heart failure in Tgaq*44 mice

Keywords: Hypertrophy; Heart failure; Metabolic remodeling; Structural remodeling; PPARα;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Mapping the response of human fibroblast growth factor 21 (FGF21) promoter to serum availability and lipoic acid in HepG2 hepatoma cells

Keywords: ACTB; β-actin; CPT1A; carnitine palmitoyltransferase 1α; CBP; CREB binding factor; CREB; cAMP response element-binding protein; DHLA; DL-α-dihydrolipoic acid; Elk-1; ETS domain-containing Elk-1; Elk-4; ETS domain-containing Elk-4 (aka SAP-1); ENCODE; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFSC; high fructose corn syrup; ALT; alanine aminotransferase; AST; aspartate aminotransferase; RBP4; retinol binding protein 4; FGF21; fibroblast growth factor 21; CRP; C-reac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors

Keywords: NAFLD; non-alcoholic fatty liver disease; NF-κB; nuclear factor-kappa B; Bcl-3; B cell leukemia-3; NASH; non-alcoholic steatohepatitis; HCC; hepatocellular carcinoma; TNF; tumor necrosis factor-alpha; JNK; c-jun N-terminal protein kinase; PPARα; peroxis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperPeroxisome proliferator-activated receptor alpha deficiency impairs regulatory T cell functions: Possible application in the inhibition of melanoma tumor growth in mice

Keywords: CD4+CD25+ regulatory T cells; PPARα; B16 melanoma tumor; Perforin; PPARα; Peroxisome proliferator-activated receptor-alpha; Foxp3; forkhead box P3; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; TGF-β; transforming growth factor-β; Treg; CD4+CD2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitory effects of Phyllanthus emblica L. on hepatic steatosis and liver fibrosis in vitro

Keywords: α-SMA; alpha-smooth muscle actin; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; CPT-1; carnitine palmitoyl transferase-1; EA; ellagic acid; FAS; fatty acid synthase; FFA; free fatty acid; HSCs; hepatic stellate cells; NAFLD; nonalcohol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells

Keywords: ACC; acetyl-CoA carboxylase; Akt; protein kinase B; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; apoE; apolipoprotein E; CPT1α; carnitine palmitoyltransferase 1α; DGAT1; diacylglycerol O-acyltransferase 1; DGAT2; diacylglycerol O-acyltran

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease

Keywords: Diabetic nephropathy; TXNIP; Lipid accumulation; Akt/mTOR; SREBP-1; PPARα;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه