دانلود مقالات ISI درباره گیرنده پیش گران X + ترجمه فارسی

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR

Keywords: گیرنده پیش گران X; Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Alisol B 23-acetate from the rhizomes of Alisma orientale is a natural agonist of the human pregnane X receptor

Keywords: گیرنده پیش گران X; Alisol B 23-acetate; Alisma orientale; Pregnane X receptor; Alisma rhizome; Nuclear receptor; CYP3A4; cytochrome P450 3A4; DMEs; drug metabolizing enzymes; HPH; human primary hepatocyte; ABA; alisol B 23-acetate; PXR; pregnane X receptor; SRC-1; steroid r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnenolone 16α-carbonitrile ameliorates concanavalin A-induced liver injury in mice independent of the nuclear receptor PXR activation

Keywords: گیرنده پیش گران X; PXR; pregnane X receptor; PCN; pregnenolone 16α-carbonitrile; Con A; concanavalin A; DSS; dextran sulfate sodium; TNF; tumor necrosis factor; LPS; lipopolysaccharide; NF-κB; nuclear factor κB; MPO; myeloperoxidase; SOCS1; suppressor of cytokine signali

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Epigallocatechin gallate induces a hepatospecific decrease in the CYP3A expression level by altering intestinal flora

Keywords: گیرنده پیش گران X; Cytochrome P450; Epigallocatechin gallate; Green tea polyphenol; Clostridium spp.; Pregnane X receptor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Intracellular localization of pregnane X receptor in HepG2 cells cultured by the hanging drop method

Keywords: گیرنده پیش گران X; Pregnane X receptor; Three-dimensional culture; Hanging drop method; Cytoplasmic retention; Nuclear translocation; Human hepatocarcinoma cell; 2D; two-dimensionally; 3D; three-dimensionally; CAR; constitutive androstane receptor; CCRP; cytoplasmic CAR ret

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals

Keywords: گیرنده پیش گران X; Pregnane X receptor; Common carp; Human; Transient transactivation assay; Pharmaceuticals; Azole fungicides;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage

Keywords: گیرنده پیش گران X; PXR; pregnane X receptor; AhR; aryl hydrocarbon receptor; DRE; dioxin response element; BaP; benzo[a]pyrene; RIF; rifampicin; H2Ax; histone 2Ax; CAR; constitutive androstane receptor; FXR; farnesoid X receptor; CYP450; cytochrome P450; EROD; 7-ethoxyresor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between NR1I2 polymorphisms and inflammatory bowel disease risk: A systematic review and meta-analysis

Keywords: گیرنده پیش گران X; NR1I2; Homo sapiens nuclear receptor subfamily 1 group I member 2; IBD; inflammatory bowel diseases; UC; Ulcerative Colitis; CD; Crohn's Disease; OR; odd radio; CI; confidence interval; PPARα; peroxisome proliferator-activated receptor alpha; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes

Keywords: گیرنده پیش گران X; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; DRE; dioxin responsive element; DMEM; Dulbecco modified Eagle medium; DMSO; dimethylsulfoxide; EMSA; electrophoretic mobility shift assay; EROD; 7-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and this is a potential source of its mixture interactions with other chemicals

Keywords: گیرنده پیش گران X; Gene expression; Mixture model; Nuclear receptor; Aquatic toxicology; Induction; Concentration-dependent; ADH; Alcohol dehydrogenase; AUC; Area under the curve; ABC transporter; ATP-binding cassette transporter; BPA; Bisphenol A; CATAM; Computational Appr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression

Keywords: گیرنده پیش گران X; FGF; fibroblast growth factor; PXR; pregnane X receptor; NR; nuclear receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; HFD; high fat diet; KO; knockout; ob; obesity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling pathway

Keywords: گیرنده پیش گران X; Carboxylesterases; Type 2 diabetes; Pregnane X receptor; P-glycoprotein; AMP-activated protein kinase; c-Jun N-terminal kinase; Metformin (PubChem CID: 4091); Para-nitrophenylacetate (PubChem CID: 6931101); Clopidogrel bisulfate (PubChem CID: 115366); Iri

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Xenobiotics and the Glucocorticoid Receptor

Keywords: گیرنده پیش گران X; GC; Glucocorticoids; GR; Glucocorticoid Receptor; NR; Nuclear receptor; PXR; Pregnane X receptor; CAR; Constituitive androstane receptor; SCN; Supra-chiasmic nucleus; CBG; Corticosteroid binding globulin; HSD; Hydroxysteroid dehydrogenase; MR; Minerocorti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The xenobiotic sensor PXR in a marine flatfish species (Solea senegalensis): Gene expression patterns and its regulation under different physiological conditions

Keywords: گیرنده پیش گران X; Pregnane X receptor; Xenobiotic sensor; Warfarin; Gene expression; Pollution; Evolutionary conservation; Senegalese sole Solea senegalensis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity

Keywords: گیرنده پیش گران X; Ursolic acid; Pregnane x receptor; Constitutive androstane receptor; Cytochrome P450; Rifampin; Isoniazid; CAR; constitutive androstane receptor; CITCO; 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde o-(3,4-dichlorobenzyl)-oxime; CYP450; cyt

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor

Keywords: گیرنده پیش گران X; DR; direct repeat; EMSA; electrophoretic mobility shift assay; ER; everted repeat; LXR; liver X receptor; PXR; pregnane X receptor; RXR; retinoid X receptor; SMPDL; sphingomyelin phosphodiesterase acid-like; Rifampin (PubChem CID: 6243627); GW3965 hydroch

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC50 for a proof-of-principle study

Keywords: گیرنده پیش گران X; 17β-Hydroxysteroid dehydrogenase type 1; Enzyme inhibitor; Steroidogenic enzymes; Estrogen-dependent disease; Intracrinology; (h)17β-HSD1; (human) 17β-hydroxysteroid dehydrogenase type 1; (h)17β-HSD2; (human) 17β-hydroxysteroid dehydrogenase type 2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Vitamin K and osteoporosis: Myth or reality?

Keywords: گیرنده پیش گران X; VK; Vitamin K; OC; Osteocalcin; RCTs; Randomized Control Trials; BMD; Bone Mineral Density; BTM; Bone Turnover Markers; VD; Vitamin D; Gla; γ-carboxyglutamic acid; PT; Prothrombin Time; MGP; Matrix Gla Protein; Gas-6; Growth arrest-specific 6 protein; uc

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells

Keywords: گیرنده پیش گران X; ADH; Alcohol dehydrogenase; AHR; Aryl hydrocarbon receptor; ALD; Alcohol liver disease; ARNT; AHR nuclear translocator; CAR; Constitutive androstane receptor; CYP; Cytochrome P450; ER; Estrogen receptor; OCP; Organochlorine pesticide; POP; Persistent orga

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: گیرنده پیش گران X; RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

RNAi suppression of nuclear receptor genes results in increased susceptibility to sulfoxaflor in brown planthopper, Nilaparvata lugens

Keywords: گیرنده پیش گران X; AHR; aryl hydrocarbon receptor; BLAST; basic local alignment search tool; CAR; constitutive androstane receptor; CYP; cytochrome P450; DBD; DNA-binding domain; ERR; estrogen-related receptor; EST; expressed sequence tag; GR; glucocorticoid receptor; HNF4;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: گیرنده پیش گران X; Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal

Keywords: گیرنده پیش گران X; CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewInfluence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of P-glycoprotein and cytochrome P450 3A in sheep

Keywords: گیرنده پیش گران X; P-gp,MDR1,ABCB1; P-glycoprotein; CYP3A4; cytochrome P450 3A; VDR; vitamin D receptor; PXR; pregnane X receptor; RXR; αretinoid X receptor; BW; body weight; 25-OHD3; 25-hydroxyvitamin D3; 1,25-(OH)2D3; 1,25-dihydroxyvitamin D3; Cholecalciferol; Ruminant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Pregnane receptor gene polymorphisms, pathogenic bacteria distribution and drug sensitivity, and TCM syndrome differentiation in patients with cholelithiasis

Keywords: گیرنده پیش گران X; Cholelithiasis; Cholesterol gallstone disease; Drug resistance test; Pregnane X receptor; Polymorphism; Traditional Chinese medicine syndromes;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells

Keywords: گیرنده پیش گران X; Pregnane X receptor; SUMOylation; Transcriptional activity; CYP3A4; P-gpSUMO, small ubiquitin-related modifier; PXR, pregnane X receptor; RIF, rifampicin; CYP3A4, cytochrome P450 3A4; P-gp, p-glycoprotein; MDZ, midazolam; 1′-OHMDZ, 1′-Hydroxymidazolam; Rh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

Keywords: گیرنده پیش گران X; Human iPS cells; Enterocyte-like cells; CYP3A4 induction; Nuclear receptor; CDX2; caudal type homeobox 2; CYP3A4; cytochrome P450 3A4; DEX; dexamethasone; EGF; epidermal growth factor; FGF2; fibroblast growth factor 2; FXR; farnesoid X receptor; GR; gluco

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

New brominated flame retardants and their metabolites as activators of the pregnane X receptor

Keywords: گیرنده پیش گران X; CYP; cytochrome P450; PCR; polymerase chain reaction; PPAR; peroxisome proliferator activated receptor; PXR; pregnane X receptor; TBB; 2-ethylhexyl 2,3,4,5-tetrabromobenzoate; TBPH; bis(2-ethylhexyl) tetrabromophthalate; TBBA; 2,3,4,5-tetrabromobenzoic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

Keywords: گیرنده پیش گران X; CYP; cytochrome P450; miRNA; microRNA; DMETs; drug metabolizing enzymes and transporters; CAR; constitutive androstane receptor; PXR; pregnane X receptor; RE; response element; 3′-UTR; 3′-untranslated region; SULT; sulfotransferase; Ago; argonaute RIS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

RXRα, PXR and CAR xenobiotic receptors mediate the apoptotic and neurotoxic actions of nonylphenol in mouse hippocampal cells

Keywords: گیرنده پیش گران X; bbb; blood-brain barrier; CAR; constitutive androstane receptor; DIV; day in vitro; DMSO; dimethyl sulfoxide; EDC; endocrine-disrupting chemical; ER; estrogen receptor; LDH; lactate dehydrogenase; NP; nonylphenol; PBS; phosphate-buffered saline; PXR; pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4

Keywords: گیرنده پیش گران X; FLU; flutamide; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; 3-MC; 3-methylcholanthrene; ABCC4; ATP-binding cassette sub-family C member 4; MRP4; mul

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Insights into CYP2B6-mediated drug-drug interactions

Keywords: گیرنده پیش گران X; CAR; constitutive androstane receptor; C/EBP; CCAAT/enhancer-binding protein; CHOP; cyclophosphamide-doxorubicin-vincristine-prednisone; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime); COUP-TF; chic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450

Keywords: گیرنده پیش گران X; AhR; Aryl Hydrocarbon Receptor; CCBs; calcium channel blockers; CYP; cytochrome P450; DEX; dexamethasone; DMSO; dimethysulfoxide; GR; Glucocorticoid Receptor; HLMs; human liver microsomes; PXR; pregnane X receptor; RIF; rifampicin; TCDD; 2,3,7,8 tetrachlo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes

Keywords: گیرنده پیش گران X; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; PCN; pregnenolone-16α-carbonitrile; PXR; pregnane X receptor; GLUT2; glucose transporter 2; GCK; glucokinase; PDK2; pyruvate dehydrogenase kinase isoenzyme 2; PEPCK1; phosphoenolpyruvate carboxykinase 1; G6

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Investigation of the dominant positive effect of porcine farnesoid X receptor (FXR) splice variant 1

Keywords: گیرنده پیش گران X; CAR; constitutive androstane receptor; PXR; pregnane X receptor; FXR; farnesoid X receptor; CYP3A4; cytochrome P450 3A4; SULT2A1; hydroxysteroid sulfotransferase; UGT2B4; UDP-glucuronosyltransferase 2B4; GRβ; glucocorticoid receptor β; ERE; estrogen res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

In vivo induction of CYP in mice by carbamazepine is independent on PXR

Keywords: گیرنده پیش گران X; CBZ; carbamazepine; CYP; cytochrome P450; PXR; pregnane X receptor; CBZ-E; CBZ 10,11-epoxide; CAR; constitutive androstane receptor; Wt; wild-type; ALT; alanine aminotransferase; AST; aspartate aminotransferase; q-PCR; quantitative real-time PCR; Inductio

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures

Keywords: گیرنده پیش گران X; CYP1A1; CYP1A2; Aryl hydrocarbon receptor; Pregnane X receptor; 3D culture; Spheroid; Liver cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease

Keywords: گیرنده پیش گران X; 3-Hydroxyflavone (PubChem CID: 11349); Galangin (PubChem CID: 5281616); Datiscetin (PubChem CID: 5281610); Kaempferol (PubChem CID: 5280863); Morin (PubChem CID: 5281670); Quercetin dihydrate (PubChem CID: 5284452); Isorhamnetin (PubChem CID: 5281654); Ta

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes

Keywords: گیرنده پیش گران X; AhR; arylhydrocarbon receptor; BaP; benzo[a]pyrene; NAFLD; non-alcoholic fatty liver disease; TCDD; 2,3,7,8-tetrachlorodibenzodioxin; SDS; sodiumdodecyl-sulfate; CAR; constitutive androstane receptor; PXR; pregnane X receptor; ARNT; aryl hydrocarbon recep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Tunicate pregnane X receptor (PXR) orthologs: Transcript characterization and natural variation

Keywords: گیرنده پیش گران X; AF-1; transcription activation function 1; AR; androgen receptor; BsVDR/PXRα; Botryllus schlosseri VDR/PXR ortholog α; BSA; bovine serum albumin; bp; base pair; CAR; constitutive androstane receptor; CiVDR/PXRα; Ciona intestinalis VDR/PXR ortholog α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Identification and interplay of sequence specific DNA binding proteins involved in regulation of human Pregnane and Xenobiotic Receptor gene

Keywords: گیرنده پیش گران X; Pregnane X Receptor; Gene regulation; Promoter-reporter assays; Cis-elements; Transcription factors; hnRNPK; Sp1; EMSA; ChIP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently

Keywords: گیرنده پیش گران X; CMV; cytomegalovirus; DBD; DNA-binding domain; GAL4; yeast regulatory protein GAL4; hPXR; human PXR; LBD; ligand-binding domain; NR1I2; nuclear receptor subfamily 1 group I member 2, a. k. a pregnane X receptor; pbPXR; polar bear PXR; PXR; pregnane X rece

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Tanshinone IIA exerts protective effects in a LCA-induced cholestatic liver model associated with participation of pregnane X receptor

Keywords: گیرنده پیش گران X; BAs; Bile acids; LCA; lithocholic acid; Tan IIA; Tanshinone IIA; siRNA; Small interfering RNA; RIF; Rifampicin; PCN; pregnenolone 16a-carbonitrile; PXR; pregnane X receptor; CAR; constitutive androstane receptor; VDR; vitamin D receptor; Tanshinone IIA (P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production

Keywords: گیرنده پیش گران X; AO; aldehyde oxidase; ANA; antinuclear antibody; AADAC; arylacetamide deacetylase; BNPP; bis(4-nitrophenyl)phosphate; CES; carboxylesterase; CYP; cytochrome P450; DTNB; 5,5′-dithiobis(2-nitrobenzoic acid); EDTA; ethylenediamine-N,N,N′N′-tetraacetic

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Diethylstilbestrol-scaffold-based pregnane X receptor modulators

Keywords: گیرنده پیش گران X; Pregnane X receptor; PXR agonist; PXR antagonist; Diethylstilbestrol; Mimetic; Solomonsterol; ABC; ATP-binding cassette; AF-2; activation function 2; BCRP; breast cancer resistance protein; DES; diethylstilbestrol; MRP; multiple resistance drug protein;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Utility of an appropriate reporter assay: Heliotrine interferes with GAL4/upstream activation sequence-driven reporter gene systems

Keywords: گیرنده پیش گران X; Firefly luciferase inhibition; Nuclear receptor; Transactivation assay; LBD; ligand-binding domain; DBD; DNA-binding domain; UAS; upstream activating sequence; PXR; pregnane X receptor; mRNA; messenger RNA;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The protective effect of piperine on dextran sulfate sodium induced inflammatory bowel disease and its relation with pregnane X receptor activation

Keywords: گیرنده پیش گران X; Piperine; Cytochrome 3A4; Pregnane X receptor; Inflammatory bowel disease; Nuclear factor B

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Cycloartane-type triterpenes from Euphorbia fischeriana stimulate human CYP3A4 promoter activity

Keywords: گیرنده پیش گران X; Euphorbia fischeriana; Cycloartane; CYP3A4; Promoter; Pregnane X receptor;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Incisterols, highly degraded marine sterols, are a new chemotype of PXR agonists

Keywords: گیرنده پیش گران X; Nuclear receptors; Pregnane X receptor; Plakortis cfr. lita; Incisterols; Molecular docking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Pregnane X receptor is required for IFN-α-mediated CYP3A29 expression in pigs

Keywords: گیرنده پیش گران X; Cytochrome P450; CYP3A29; Pregnane X receptor; Interferon (IFN)-α; Pig;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه