Keywords: پروژانولین; CTLs; CD8+ T lymphocytes; ELISA; enzyme-linked immunosorbent assay; ITP; immune thrombocytopenia; IBD; inflammatory bowel disease; OA; osteoarthritis; PGRN; progranulin; rPGRN; recombinant progranulin; RA; rheumatoid arthritis; SLE; systemic lupus erythem
مقالات ISI پروژانولین (ترجمه نشده)
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Keywords: پروژانولین; Progranulin; Atherosclerosis; Macrophage; Exophagy; Lysosome; Aggregated LDL;
Keywords: پروژانولین; Gaucher disease; Beta-glucocerebrosidase; LIMP-2; Saposin C; Progranulin; Heat shock proteins;
Keywords: پروژانولین; Frontotemporal lobar degeneration; Neuronal ceroid lipofuscinosis; Progranulin; Conditional knockout mice; Neuropathology; Nestin;
Keywords: پروژانولین; Cre; Cre-recombinase; DAVID; Database for Annotation, Visualization and Integrated Discovery; EPM; elevated plus maze; DRL; delayed response learning; FTLD; frontotemporal lobar degeneration; GO; gene ontology; Grn; gene name for progranulin; NOR; novel o
Keywords: پروژانولین; Progranulin; β-Glucocerebrosidase; Gaucher disease; Lysosomal storage diseases;
Keywords: پروژانولین; Progranulin; Endotoxemia; Acute kidney injury; Apoptosis; Inflammation;
Keywords: پروژانولین; Pain; Nerve injury; Sensory neuron; Autophagy; Progranulin; Dorsal root ganglia;
Keywords: پروژانولین; Frontotemporal Lobar degeneration; Progranulin; Interleukin-6; Biomarkers;
Keywords: پروژانولین; Logopenic; Primary progressive aphasia; Pittsburgh compound B; Magnetic resonance imaging; FDG-PET; Progranulin; Beta-amyloid;
Keywords: پروژانولین; Progranulin; TNFR1&2; DR3; Hyperphosphorylation of Ser81; Alternative conversion; Neoantigen; Proinflammatory autoantibody; PP1; PKCβ1
Keywords: پروژانولین; acute kidney injury; hypoxia; inflammation; pattern-recognition receptors; progranulin;
Keywords: پروژانولین; Progranulin; Bipolar disorder; Inflammation; Biomarker; Neurodegeneration; Genetic variants
Keywords: پروژانولین; NCL, neuronal ceroid lipofuscinosis; CLN11, neuronal ceroid lipofuscinosis-11; ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layerNeurodegeneration; Progranulin; Autofluorescent storage material; Neuronal ceroid lipofuscinosis
Keywords: پروژانولین; FTLD; Progranulin; Magnetic resonance imaging; Cortical thickness; Diffusion tensor; Resting-state functional MRI;
Keywords: پروژانولین; 2-DE; two-dimensional gel electrophoresis; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; FPPS; farnesyl pyrophosphate synthase; IPP; isopentyl diphosphate; LC; liquid chromatography; MALDI-ToF; matrix-assisted laser desorption/ionization-time
Keywords: پروژانولین; Progranulin; Granulin; Frontotemporal dementia; Frontotemporal lobar degeneration; MRI; Cortical thickness; Preclinical;
Keywords: پروژانولین; Granulin; Progranulin; Mutations; Gene expression; Frontotemporal lobar degeneration; Frontotemporal dementia; Inflammation;
Keywords: پروژانولین; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ANOVA; Analysis of variance; Aβ; amyloid β; bHLH; basic Helix-Loop-Helix; C4; complement C4; CLEAR; coordinated lysosomal expression and regulation; Cyba; cytochrome b-245 light chain; DW; d
Keywords: پروژانولین; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; EDTA; ethylenediaminetetraacetic acid; FTLD; frontotemporal lobar degeneration; GFAP; glial fibrillary acidic protein; HE; hematoxylin and eosin; HPRT; hypoxanthine phosphoribosyltransferase;
Keywords: پروژانولین; Frontotemporal degeneration; Treatment; Tau; Progranulin; TDP-43;
Progranulin: A key player in autoimmune diseases
Keywords: پروژانولین; Progranulin; TNF; TNFR; Autoimmune diseases;
Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI
Keywords: پروژانولین; Frontotemporal dementia; MAPT protein, human; GRN protein, human; C9orf72, human; Diffusion Tensor Imaging; Resting-state functional MRI; Multimodal MRI; classification; machine learning; 3DT1w; 3-dimensional T1-weighted; AUC; Area under the receiver oper
Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers
Keywords: پروژانولین; PGRN; Progranulin; EC; esophageal cancer; IHC; immunohistochemistry; LMVD; lymph microvessel density; LVSI; lymph vessel space invasion; PFS; progression-free survival; OS; overall survival; Progranulin; VEGF-C; Lymphangiogenesis; Esophageal cancer; Nomog
Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers
Keywords: پروژانولین; GRN; progranulin; pGRN+; presymptomatic progranulin mutation carriers; GRN+; symptomatic progranulin mutation carriers; yCTL; young healthy controls; eCTL; elderly healthy controls; FTD; frontotemporal degeneration; GM; gray matter; WM; white matter; GMD;
Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease
Keywords: پروژانولین; Progranulin; Gaucher disease; Chitinase-3-like-1; Lysosomal storage diseases;
A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity
Keywords: پروژانولین; Tilapia; Progranulin; Granulin; Innate immunity; Vibrio; Transgenic zebrafish; Alternative splicing;
NG2/CSPG4 and progranulin in the posttraumatic glial scar
Keywords: پروژانولین; Traumatic brain injury; Glial scar; Astrocytes; Chondroitin sulfate proteoglycan; Perlecan; Progranulin; Microglia; ADAM10; Receptor protein phosphatase; Growth factor;
CSF pro-orexin and amyloid-β38 expression in Alzheimer's disease and frontotemporal dementia
Keywords: پروژانولین; Alzheimer's disease; Frontotemporal dementia; Orexin; Progranulin; C9orf72; Amyloid β-38;
Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disorders
Keywords: پروژانولین; GRN; Progranulin; Parkinsonism;
Missense mutation in GRN gene affecting RNA splicing and plasma progranulin level in a family affected by frontotemporal lobar degeneration
Keywords: پروژانولین; Frontotemporal lobar degeneration; GRN; Mutation; Progranulin; RNA; Splicing;
An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations
Keywords: پروژانولین; Frontotemporal dementia; Progranulin; Genetics; Nimodipine; Dementia;
Increased expression of PGRN protein in follicular fluid and mRNA in granulosa cells in overweight patients with polycystic ovary syndrome
Keywords: پروژانولین; BMI; Body mass index; CRP; C-reactive protein; E2; Estradiol; ELISA; The enzyme-linked immunosorbent assay; FBG; Fasting plasma glucose; FF; Follicular fluid; FIN; Fasting blood insulin; FSH; Follicle-stimulating hormone; GCs; Granulosa cells; GnRHant; Go
C5a/C5aR pathway accelerates renal ischemia-reperfusion injury by downregulating PGRN expression
Keywords: پروژانولین; C5a/C5aR pathway; Ischemic-reperfusion injury; Progranulin; NF-κB;
Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model
Keywords: پروژانولین; Progranulin; Monoclonal antibody; Hybridoma; Prokaryotic expression; Eukaryotic expression;
Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas
Keywords: پروژانولین; GP88; Progranulin; Lymphoid malignancies; Prognosis, DLBCL;
Rapprochement entre neurologie et psychiatrie : le cas prototypique de la dégénérescence frontotemporale
Keywords: پروژانولین; Dégénérescence frontotemporale; Psychiatrie; Psychose; Génétique; Progranuline; Frontotemporal dementia; Psychiatry; Psychosis; Genetics; Progranulin;
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases
Keywords: پروژانولین; Progranulin; Frontotemporal dementia; Phenotype;
CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN
Keywords: پروژانولین; Proteomics; Granulin; Progranulin; Clusterin; Neuroinflammation; Biomarkers;
Serum progranulin levels are elevated in patients with chronic hepatitis B virus infection, reflecting viral load
Keywords: پروژانولین; Progranulin; HBV; Growth factor; Infection; Patients;
Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals
Keywords: پروژانولین; Frontotemporal lobar degeneration; Progranulin; Sortilin; Single nucleotide polymorphism; ELISA; Decoy receptor; Biomarker; Aging;
Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients
Keywords: پروژانولین; Frontotemporal dementia; iPSCs; Microarray; Neurons; Progranulin; SAHA;
Progranulin is increased in human and murine lipodystrophy
Keywords: پروژانولین; Adipokine; Adipose tissue; Leptin treatment; Lipodystrophy; Progranulin
Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features
Keywords: پروژانولین; Progranulin; GRN; Mutation; Frontotemporal lobar degeneration; Pathogenetic; Functional analysis;
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin
Keywords: پروژانولین; Progranulin; Granulin; Frontotemporal dementia; Missense mutation; Protein processing;
Loss of exosomes in progranulin-associated frontotemporal dementia
Keywords: پروژانولین; Progranulin; GRN; Null mutations; Human primary fibroblasts; Exosomes; Extracellular vesicles;
Increasing progranulin levels and blockade of the ERK1/2 pathway: Upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia
Keywords: پروژانولین; FTLD-TDP; Lymphocytes; Cell proliferation; Progranulin; ERK1/2; CDK6;
Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice
Keywords: پروژانولین; Progranulin; Osteoclast; Osteoblast; TNF-α; Bone metabolism; ERK1/2;
Clinical and MRI correlates of disease progression in a case of nonfluent/agrammatic variant of primary progressive aphasia due to progranulin (GRN) Cys157LysfsX97 mutation
Keywords: پروژانولین; Nonfluent/agrammatic variant of primary progressive aphasia; Progranulin; Voxel-based morphometry; Tensor-based morphometry; Diffusion tensor MRI; White matter damage;
Growth factor progranulin contributes to cervical cancer cell proliferation and transformation in vivo and in vitro
Keywords: پروژانولین; Cervical cancer; Progranulin; Cell proliferation; Transformation