دانلود مقالات ISI درباره پروتئین کیناز B + ترجمه فارسی

The anti-apoptotic activity associated with phosphatidylinositol transfer protein α activates the MAPK and Akt/PKB pathway

Keywords: پروتئین کیناز B; PI-TP; phosphatidylinositol transfer protein; PI; phosphatidylinositol; PC; phosphatidylcholine; PLA; phospholipase A; MAPK; mitogen-activated protein kinase; ERK; extracellular signalling related kinase; IAP; inhibitor of apoptosis protein; PKB; protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Linker region of Akt1/protein kinase Bα mediates platelet-derived growth factor-induced translocation and cell migration

Keywords: پروتئین کیناز B; PDGF; platelet-derived growth factor; PKB; protein kinase B; PI3K; phosphatidylinositol 3-kinase; MEF; mouse embryo fibroblast; P-Rex1; PIP3-dependent Rac exchanger1; Girdin; girders of actin filaments; Migration; PI3K; Akt/PKB; Linker region; PDGF;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo

Keywords: پروتئین کیناز B; AKT; protein kinase B; EC; endothelial cell; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal regulated kinase; HE; hematoxyline eosine; HCC; hepatocellular carcinoma; LDH; lactat dehydrogenase; p38 MAPK; mitogen activated protein kinas

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of Akt during hibernation in Richardson's ground squirrels

Keywords: پروتئین کیناز B; PKA; cAMP-dependent protein kinase A; PKC; Ca2+-activated, phospholipid-dependent protein kinase C; GSK; glycogen synthase kinase; PP; protein phosphatase; PMSF; phenylmethylsulfonyl fluoride; DTT; dithiothreitol; IGF; insulin-like growth factor; PH; plec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Extracellular signal-regulated kinase (ERK) and protein kinase B (AKT) pathways involved in spinal cord stimulation (SCS)-induced vasodilation

Keywords: پروتئین کیناز B; Spinal cord stimulation; Extracellular signal-regulated kinase; Protein kinase B; Vasodilation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Preconditioning by inhaled nitric oxide prevents hyperoxic and ischemia/reperfusion injury in rat lungs

Keywords: پروتئین کیناز B; Glycogen synthase kinase; Hyperoxia; Lung permeability; Mitogen-activated protein kinases; Nitric oxide; Preconditioning; Protein kinase B;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Dexamethasone and GLP-2 administered to rat dams during pregnancy and lactation have late effects on intestinal sugar transport in their postweanling offspring

Keywords: پروتئین کیناز B; Akt/PKB; Protein kinase B; BBM; brush border membrane; BLM; basolateral membrane; DEX; dexamethasone; EGF; epidermal growth factor; GC; glucocorticosteroids; GLP-2; glucagon-like peptide-2; GLUT; glucose transporter; GSK-3; glycogen synthase kinase 3; IGF

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

A cell-permeable peptide inhibitor TAT-JBD reduces the MPP+-induced caspase-9 activation but does not prevent the dopaminergic degeneration in substantia nigra of rats

Keywords: پروتئین کیناز B; Akt/PKB; protein kinase B; Apaf-1; apoptotic protease activating factor-1; JNK; c-Jun N-terminal kinase; LEHD; Leu-Glu-His-Asp acid; MAPK; mitogen-activated protein kinase; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrop

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

A cell model system to study regulation of phosphotidylinositol 3-kinase and protein kinase B activity by cytokines/growth factors produced by type I collagen stimulated immune cells from patients with systemic sclerosis

Keywords: پروتئین کیناز B; Systemic sclerosis; platelet; nitrotyrosylation of protein; nitric oxide synthase; collagen; protein kinase B;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

SB203580 enhances interleukin-1 receptor antagonist gene expression in IFN-γ-stimulated BV2 microglial cells through a composite nuclear factor-κB/PU.1 binding site

Keywords: پروتئین کیناز B; IL-1 receptor antagonist; Microglia; IFN-γ; SB203580; Protein kinase B; NF-κB/PU.1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Modifications of the GSK3β substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics

Keywords: پروتئین کیناز B; Protein kinase B; Akt; Cancer; Peptidomimetics; Substrate-mimetic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Pirfenidone inhibits TGF-β expression in malignant glioma cells

Keywords: پروتئین کیناز B; boc-RVRR-amc; butoxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarine; dec-RVKR-cmk; decanoyl-Arg-Val-Lys-Arg-chloromethylketone; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; LDH; lactate dehydrogenase; LAP; latency associated pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Protein kinase C-dependent antilipolysis by insulin in rat adipocytes

Keywords: پروتئین کیناز B; β-AR; β-adrenergic receptor; α-AR; α-adrenergic receptor; PKA; protein kinase A; PKC; protein kinase C; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase; PI3K; phosphatidylinositol 3-kinase; PIP3; phosphatidylinositol 3,4,5-tripho

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Insulin signaling in hypertension

Keywords: پروتئین کیناز B; Glucose uptake; Protein kinase B; Adrenergic receptors; Angiotensin II; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: Mechanisms and consequences

Keywords: پروتئین کیناز B; Copper; Zinc; Insulin signaling; Akt; Protein kinase B; FoxO; Protein tyrosine phosphatases; Reactive oxygen species; C. elegans

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase

Keywords: پروتئین کیناز B; PD; Parkinson's disease; ROS; reactive oxygen species; PI3K; phosphatidylinositol 3-kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PKB; protein kinase B; COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; CM; conditioned media

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Apoptosis in the pathophysiology of diabetes mellitus

Keywords: پروتئین کیناز B; Akt; protein kinase B; Bad; Bcl-2 antagonist of cell death; Bax; Bcl-2 antagonist X; Bcl; B-cell leukaemia/lymphoma; FADD; Fas-associated death domain containing protein; FFA; free fatty acid; IAPP; islet amyloid polypeptide; JNK; c-Jun N-terminal kinase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

Keywords: پروتئین کیناز B; Inhibitors of Akt; Akt1; Akt2; Akt3; PKA; PKB; protein kinase B; GSK3; FL5.12-Akt1; X-ray; Anticancer; Apoptosis; Antitumor; Pharmacokinetics; Kinase inhibitors; Structure-based design

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia

Keywords: پروتئین کیناز B; brain ischemia; Akt; vanadyl compound; FOXO; neuronal death; Fas-ligand; Akt; protein kinase B; DTT; dithiothreitol; FADD; Fas-associated death domain; FBDP; fodrin breakdown product; FOXO; forkhead box transcription factor, class O; MCA; middle cerebral

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCα

Keywords: پروتئین کیناز B; PI 3-kinase; phosphoinositide 3-kinase; PKB; protein kinase B; PDK-1; phosphoinositide-dependent kinase-1; PKC; protein kinase C; mTOR; mammalian target of rapamycin; c48/80; compound 48/80; BAPTA; bis-(o-aminophemoxy)-ethane-N,N,N′,N′-tetraacetic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of Protein Kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines

Keywords: پروتئین کیناز B; Protein Kinase B; PTEN; SHIP2; Phosphatidylinositol 3-kinase; Prostate; Cancer; Cell line

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3β signaling

Keywords: پروتئین کیناز B; Zinc; Neuronal cell death; Akt; Protein kinase B; Phosphatidylinositol-3-kinase; Glycogen synthase kinase-3β; Tau; β-catenin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts

Keywords: پروتئین کیناز B; Focal Adhesion Kinase; Protein kinase B; SMAD proteins; p38 MAPK; Transforming growth factor-beta; Apoptosis; Anoikis; Fibroblasts

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1α and promotes cell viability

Keywords: پروتئین کیناز B; Hypoxia; Protein kinase B; Hypoxia-inducible factor-1α; Kidney; Fibrosis; Insulin; Cell viability

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Design and synthesis of pyridine–pyrazolopyridine-based inhibitors of protein kinase B/Akt

Keywords: پروتئین کیناز B; Protein kinase B; Akt inhibitor; Serine/threonine kinase; Pyrazolopyridine

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Involvement of the ERK/MAP kinase signalling pathway in milli-calpain activation and myogenic cell migration

Keywords: پروتئین کیناز B; BCA; bicinchoninic acid; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DTT; DL-dithiothreitol; EGF; epidermal growth factor; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid; ERK; extracellular-signal regulat

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

The 47 kDa Akt substrate associates with phosphodiesterase 3B and regulates its level in adipocytes

Keywords: پروتئین کیناز B; Adipocyte; Akt; Insulin; Lipolysis; Phosphodiesterase 3B; Protein kinase B; gi74193400

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Ras: The stress and the strain

Keywords: پروتئین کیناز B; ERK; extracellular signal-regulated kinase; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; GqPCR; Gq protein-coupled receptor; GSH; glutathione; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PI3K; phosphoi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Keywords: پروتئین کیناز B; Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Keywords: پروتئین کیناز B; Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Atypical protein kinase C in glucose metabolism

Keywords: پروتئین کیناز B; PKC; protein kinase C; aPKC; atypical isoforms of PKC; Par6; partitioning-defective protein 6; Par3; partitioning-defective protein 3; PDK-1; 3-phosphoinositide-dependent protein kinase 1; PI3K; phosphatidylinositol 3-kinase; EGFP; enhanced greenfluoresce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells

Keywords: پروتئین کیناز B; Platelet-derived growth factor; ATP-binding cassette transporter A1; Smooth muscle cell; Protein kinase B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

Keywords: پروتئین کیناز B; Akt inhibitors; Akt; PKB; Protein kinase B; GSK3; FL5.12-Akt1; Anticancer; Apoptosis; X-ray

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions

Keywords: پروتئین کیناز B; Stress signaling; Phosphoinositide 3-kinase (PI3K); Akt; Protein kinase B; Glucose 6-phosphatase; Insulin; C. elegans; DAF-16

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Increased cytotoxicity of ionizing radiation in combination with membrane-targeted apoptosis modulators involves downregulation of protein kinase B/Akt-mediated survival-signaling

Keywords: پروتئین کیناز B; Erucylphosphocholine; Erufosine; Apoptosis; Protein kinase B; FOXO3A; Bcl-2 proteins

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

A hypopharyngeal gland protein of the worker honeybee Apis mellifera L. enhances proliferation of primary-cultured rat hepatocytes and suppresses apoptosis in the absence of serum

Keywords: پروتئین کیناز B; Apis mellifera L.; Hypopharyngeal gland; 56-kDa protein; Royalactin; Hepatocyte proliferation; Growth factor; MAP kinase; Protein kinase B; Drosophila; Yellow protein;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Protein kinase Cδ participates in insulin-induced activation of PKB via PDK1

Keywords: پروتئین کیناز B; Protein kinase Cδ; Protein kinase B; PDK1; Insulin; Insulin signaling; Skeletal muscle; Glycogenesis; Glucose uptake

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Glutamate-dependent translational regulation in cultured Bergmann glia cells: Involvement of p70S6K

Keywords: پروتئین کیناز B; p70S6K; glutamate receptors; Bergmann glia; mTOR; translational control; Akt I; 1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate; AMPA; amino α-3-hydroxy-5-methyl-4-isoaxazolepropionate; ANOVA; analysis of variance; BAPTA-AM; 1,2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Luteolin inhibits lipopolysaccharide actions on human gingival fibroblasts

Keywords: پروتئین کیناز B; Protein kinase B; Human gingival fibroblast; Mitogen-activated protein; Lipopolysaccharide; Luteolin; Nitric oxide; Nitric oxide synthase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3

Keywords: پروتئین کیناز B; Akt; Protein kinase B; AMPK; AMP-activated kinase; GSK3; AICAR; Phenformin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The very C-terminus of protein kinase Cɛ is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1

Keywords: پروتئین کیناز B; aPKC; atypical PKC; cPKC; classic PKC; MD; molecular dynamics; nPKC; novel PKC; PAGE; polyacrylamide gel electrophoresis; PDK-1; 3-phosphoinositide-dependent kinase-1; PKA; cAMP-dependent protein kinase; PKB; protein kinase B; PKC; protein kinase C; RMSD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

Keywords: پروتئین کیناز B; Akt; Protein kinase B; Serine/threonine kinase; Indazole

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Mitochondrial contact sites: Their role in energy metabolism and apoptosis

Keywords: پروتئین کیناز B; Adenine nucleotide translocator (ANT); Voltage-dependent anion channel (VDAC); Hexokinase; Creatine kinase; Permeability transition pore; Protein kinase A; Protein kinase B; AMP Kinase; Chronic heart failure;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Differential and Epigenetic Gene Expression Profiling Identifies Frequent Disruption of the RELN Pathway in Pancreatic Cancers

Keywords: پروتئین کیناز B; ApoER2; apolipoprotein E receptor 2; COBRA; combined bisulfite restriction analysis; 5Aza-dC; 5-aza-2′-deoxycytidine; HDAC; histone deacetylase; IPMN; intraductal papillary mucinous neoplasm of the pancreas; MSP; methylation-specific polymerase chain re

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2006 سفارش ترجمه

Ceramides in insulin resistance and lipotoxicity

Keywords: پروتئین کیناز B; Ceramide; Lipotoxicity; Akt; Protein kinase B; Diabetes; Lipid; Sphingolipids; Metabolism; Metabolic syndrome; Nutrient

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2006 سفارش ترجمه

SHARP-2/Stra13/DEC1 as a potential repressor of phosphoenolpyruvate carboxykinase gene expression

Keywords: پروتئین کیناز B; 36B4; ribosomal protein 36B4; SHARP-2; enhancer of split- and hairy-related protein-2; Stra13; stimulation of retinoic acid 13; PI 3-K; phosphoinositide 3-kinase; PEPCK; phosphoenolpyruvate carboxykinase; Dex; dexamethasone; EGCG; (−)-epigallocatechin g

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of obesity on insulin signaling through JAK2 in rat aorta

Keywords: پروتئین کیناز B; Akt; protein kinase B; α PY; antibody against phosphotyrosine; eNOS; endothelial cell-nitric oxide synthase; ERK; extracellular signal-related kinase; IR; insulin receptor; IRS; insulin receptor substrate; JAK2; Janus kinase 2; MAP; mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Organo-vanadium compounds are potent activators of the protein kinase B signaling pathway and protein tyrosine phosphorylation: Mechanism of insulinomimesis

Keywords: پروتئین کیناز B; Diabetes; Insulin; Vanadium; Protein kinase B; Protein tyrosine phosphatase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Differential responsiveness of early- and late-passage endothelial cells to shear stress

Keywords: پروتئین کیناز B; Aging; Apoptosis; Endothelium; Protein kinase B; Senescence; Shear stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Cross-talk between the calcium-sensing receptor and the epidermal growth factor receptor in Rat-1 fibroblasts

Keywords: پروتئین کیناز B; Cao2+; extracellular calcium; OSE; ovarian surface epithelial; GPCR; G-protein-coupled receptor; CaR; calcium-sensing receptor; IP3; inositol triphosphate; Cai2+; intracellular calcium; ERK; extracellular signal regulated cascade; MAP kinase; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه