Keywords: CtpS; cytidine 5â²-triphosphate synthetase (synthase); IMP; inosine monophosphate; IMPDH; inosine monophosphate dehydrogenase; ERES; endoplasmic reticulum exit sites; STORM; stochastic optical reconstruction microscopy; PRPP; phosphoribosyl pyrophosphate
مقالات ISI (ترجمه نشده)
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Keywords: Immunosuppression; Gestation; Solid organ transplantation; Vaccine; Immunization; NK; natural killer; BCG; bacille Calmette-Guérin; DTPw/Hib; combined diphtheria/tetanus/whole-cell pertussis and Haemophilus influenzae type b vaccine; IPV; inactivated t
Keywords: PRPP; LC–MS/MS; HPRT; Lesch–Nyhan disease
Keywords: NATs; natural antisense transcripts; IDC; intra erythrocytic developmental cycle; PFC; Plasmodium falciparum complicated samples; PFU; Plasmodium falciparum uncomplicated samples; HS-LAS; high sense and low antisense transcripts; HAS-LS; high antisense an
Keywords: Lesch-Nyhan disease; Variants; PRPP; Phenotype-genotype; HGprt; Molecular modeling;
Analysis of Exercise Capacity of Children with Kawasaki Disease by a Coronary Artery z Score Model (ZSP Version 4) Derived by the Lambda-Mu-Sigma Method
Keywords: Kawasaki disease; exercise capacity; cardiopulmonary exercise test; coronary artery z score; AT; Anaerobic threshold; AT MET; Metabolic equivalent at anaerobic threshold; CA; Coronary artery; CAA; Coronary artery aneurysm; CPET; Cardiopulmonary exercise t
Anthranilate phosphoribosyltransferase: Binding determinants for 5â²-phospho-alpha-d-ribosyl-1â²-pyrophosphate (PRPP) and the implications for inhibitor design
Keywords: AnPRT; anthranilate phosphoribosyltransferase; IC50; absolute IC50, that is the concentration of inhibitor which decreased enzyme activity by 50%; Km; Michaelis-Menten constant; Ki; inhibition constant; Mtb; Mycobacterium tuberculosis; PPi; pyrophosphate;
Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice
Keywords: Diabetic kidney disease; Fructose metabolism; Ketohexokinase; Tubular injury; Oxidative stress; NAD metabolism; AKR1B3; aldo-keto reductase family 1 member 3; COL4; collagen 4; CTGF; connective tissue growth factor; DAG; diacylglycerol; DHAP; dihydroxyace
Silencing of the pentose phosphate pathway genes influences DNA replication in human fibroblasts
Keywords: 2d-d-Rib; 2deoxy-d-ribose; 2d-d-Rib-1P; 2deoxy-d-ribose 1-phosphate; 2d-d-Rib-5P; 2deoxy-d-ribose 5-phosphate; 6PG; 6-phosphogluconate; 6PGL; 6-phosphogluconlactone; ALDO; aldolase; BrdU; bromodeoxyuridine; DERA; deoxyribose-phosphate aldolase; d-Rib; d-r
Genome-scale metabolic network of Cordyceps militaris useful for comparative analysis of entomopathogenic fungi
Keywords: AMP; adenosine monophosphate; CHOS; chito-oligosaccharides; GER; Gene-Enzyme-Reaction; IMP; inosine monophosphate; MOS; β-1,4-manno-oligosaccharides; PPP; pentose phosphate pathway; PRPP; phosphoribosyl pyrophosphate; RNRi; ribonucleotide reductase inhib
Corynebacterium glutamicum ATP-phosphoribosyl transferases suitable for l-histidine production - Strategies for the elimination of feedback inhibition
Keywords: 2-TA; β-(2-thiazolyl)-dl-alanine; AMP; adenosine monophosphate; ATP; adenosine triphosphate; ATP-PRT; phosphoribosyltransferase; PRPP; phosphoribosyl pyrophosphate; PR-AMP; phosphoribosyl-AMP; PR-ATP; phosphoribosyl-ATP; l-Histidine biosynthesis; ATP-pho
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues
Keywords: ADPR; ADP ribose; ARTs; ADP ribose transferases; ARTD1; poly-(ADP ribose) polymerase 1; NAADP; nicotinic acid adenine dinucleotide phosphate; CR; calorie restriction; PAR; poly-(ADP ribose); PGC-1; peroxisome proliferator-activated receptor-γ coactivator
MYC and metabolism on the path to cancer
Keywords: 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer
Keywords: Tumor metabolism; NAD; NAMPT; NAPRT1; Targeted agents; ATP; adenosine triphosphate; NA; nicotinic acid; NAD; nicotinamide adenine dinucleotide; (NAM); nicotinamide; NAMN; nicotinic acid mononucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NAPRT1
Metabolic flux analysis of recombinant Pichia pastoris growing on different glycerol/methanol mixtures by iterative fitting of NMR-derived 13C-labelling data from proteinogenic amino acids
Keywords: αKG; α-ketoglutarate; GA3P; Glyceraldehyde-3-phosphate; PG2; 2-phosphoglycerate; PG3; 3-phosphoglycerate; GA3Pper; Glyceraldehyde-3-phosphate peroxisome; DHA; Dihydroxyacetone; DHAP; Dihydroxyacetone phosphate; E4P; Eritrose-4-phosphate; Rib5P; Ribose-5
Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
Keywords: Gls; glutaminase; GDH; glutamate dehydrogenase; PC; pyruvate carboxylase; GFAT; fructose-6-phosphate amido-transferase; GSH; glutathione; GlcNAc; N-acetyl-d-glucosamine; PRPP; 5-phospho-α-d-ribosyl 1-pyrophosphate; AOA; aminooxyacetate; EAA; essential am
Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase
Keywords: Mycobacterium tuberculosis; Tuberculosis; Pyrimidine; Orotate phosphoribosyltransferase; Inhibitors; Pyrimidin-2(1H)-ones compounds; TB; tuberculosis; MTB; Mycobacterium tuberculosis; OPRT; orotate phosphoribosyltransferase; OA; orotate; PRPP; α-d-5-phos
Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis
Keywords: Human NaPRT; Enzyme kinetics; Homology modeling; Molecular docking; Site-directed mutagenesis; DHAP; dihydroxyacetone phosphate; G3P; glyceraldehyde 3-phosphate; IPTG; isopropyl β-d-1-thiogalactopyranoside; Na; nicotinic acid; Nam; nicotinamide; NamR; ni
Genetic and biochemical characterization of Corynebacterium glutamicum ATP phosphoribosyltransferase and its three mutants resistant to feedback inhibition by histidine
Keywords: ATP phosphoribosyltransferase; Corynebacterium glutamicum; Feedback inhibition; Histidine; Mutagenesis; HisGCg; ATP phosphoribosyltransferase from Corynebacterium glutamicum; ATP-PRT; ATP phosphoribosyltransferase; CD; circular dichroism; DTT; dithiothrei
Enhancement of riboflavin production with Bacillus subtilis by expression and site-directed mutagenesis of zwf and gnd gene from Corynebacterium glutamicum
Keywords: FMN; flavin mononucleotide; FAD; flavin adenine dinucleotide; PPP; pentose phosphate pathway; G6PD; glucose-6-phosphate dehydrogenase; 6GPD; 6-phosphogluconate dehydrogenase; Ru5P; ribulose-5P; FBP; fructose 1,6-bisphosphate; Gra3P; d-glyceraldehyde 3-pho
Phosphate levels and expression of phosphoribosylpyrophosphate synthetase isozymes in suspension-cultured Arabidopsis thaliana cells
Keywords: Arabidopsis thaliana; Brassicaceae; Cell culture; Phosphoribosylpyrophosphate; PRPP; Synthetase; Gene expression; Enzyme; Nucleotide biosynthesis;
Biosynthesis of trigonelline from nicotinate mononucleotide in mungbean seedlings
Keywords: IMP; inosine-5â²-mononucleotide; NaAD; nicotinate adenine nucleotide; NaMN; nicotinate mononucleotide; NaR; nicotinate riboside; NMN; nicotinamide mononucleotide; NR; nicotinamide riboside; PPi; pyrophosphate; PRPP; 5-phosphoribosyl-1-pyrophosphate; Mung
Conformational changes in ammonia-channeling glutamine amidotransferases
Keywords: AS; anthranilate synthase; AsnB; asparagine synthetase B; AT; amidotransferase; CPS; carbamoyl-phosphate synthetase; CTPS; CTP synthetase; DON; 6-diazo-5-oxo-l-nor-leucine; GltS; glutamate synthase; Gln; l-glutamine; GSA; glutamyl-γ-semialdehyde; Fru6P;
Metabolic regulation and chemotherapy
Keywords: GPRT; guanine phosphoribosyltransferase (EC 2.4.2.8); IMP DH; inosine 5'-monophosphate dehydrogenase (EC 1.1.1.205); IP3; inositol-1; 4; 5-trisphosphate; MTX; methotrexate; NCI; National Cancer Institute; R-5-P; ribose-5-phosphate; PI; 1-phosphatidylino
Effects of phosphate limitation on expression of genes involved in pyrimidine synthesis and salvaging in Arabidopsis
Keywords: Arabidopsis; Gene expression; Phosphate starvation; Pyrimidine nucleotide biosynthesis; ATCase; aspartate transcarbamoylase; CarAsp; carbamoyl aspartate; CPSase; carbamoyl phosphate synthetase; DHO; dihydroorotate; FOA; 5-fluoroorotic acid; OMP; orotate-5
Monitoring fluoropyrimidine metabolism in solid tumors with in vivo 19F magnetic resonance spectroscopy
Keywords: ACC; advanced colorectal cancer; ADEPT; antibody-directed enzyme-prodrug therapy; BAU; 5-benzylacyclouridine; B0; static magnetic field; Beff; effective magnetic field; CNDP; 3-cyano-2,6-dihydroxypyridine; 5â²-DFCR; 5â²-deoxy-5-fluorocytidine; 5â²-DFUR
The 5â²-nucleotidases as regulators of nucleotide and drug metabolism
Keywords: 2,3-BPG; 2,3-bisphosphoglycerate; 3TCMP; 2â²-deoxy-3â²-thiacytidine monophosphate; 5-EddU; 5-ethynyl-dideoxyuridine; 5â²-NT; 5â²-nucleotidase; ADA; adenosine deaminase; AK; adenosine kinase; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukem