Keywords: Infections; Autoimmune disease; CD40; PTPN22; Genetic factor;
مقالات ISI (ترجمه نشده)
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Keywords: 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABHD4; α/β-hydrolase domain-containing protein 4; ABHD6; α/β-hydrolase domain-containing protein 6; ABHD12; α/β-hydrolase domain-containing protein 12; AEA; arachidonoylethanolamine; CB1; cannabino
Keywords: outcome; pathogenesis; signaling; treatment; ACS; acute coronary syndrome; APC; antigen-presenting cell; CREB; cyclic adenosine monophosphate response element-binding protein; IFN; interferon; Ig; immunoglobulin; IL; interleukin; ITIM; immunoreceptor tyro
Keywords: AAs; autoantibodies; AAT; alpha-1 antitrypsin; BB; biobreeding rat strain; BBDP; biobreeding diabetes prone; BBDR; biobreeding diabetes resistant; ELISA; enzyme-linked immunosorbent assay; GI; gastrointestinal; HLA; human leukocyte antigen; HRS; high-risk
Keywords: Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: Macrophage activation; Lipid phosphatase; SHIP; PTEN; Protein tyrosine phosphatase; Shp2; PTPN22; PTP1B; SHP-1; Protein phosphatase; MKP-1
Polymorphism rs2476601 in the PTPN22 gene is associated with type 1 diabetes in children from the South Region of Brazil
Keywords: PTPN22; SNPs; Case-control study; Type 1 diabetes mellitus; Genetic variability;
Human Leukocyte Antigen class II polymorphisms among Croatian patients with type 1 diabetes and autoimmune polyglandular syndrome type 3 variant
Keywords: AITD; autoimmune thyroid disease; APS3v; autoimmune polyglandular syndrome type 3 variant; AT; autoimmune thyroiditis; CTLA4; cytotoxic T lymphocyte antigen 4; ELISA; enzyme immunoassay; FOXP3; forehead box P3; GAD; glutamic acid decarboxylase; GD; Graves
The rs2292239 polymorphism in ERBB3 gene is associated with risk for type 1 diabetes mellitus in a Brazilian population
Keywords: T1DM; type 1 diabetes mellitus; HLA; human leukocyte antigen; GWAS; genome-wide association study; ERBB3; Erb-b2 receptor tyrosine kinase 3; SNP; single nucleotide polymorphism; EGFR; epidermal growth factor receptor; PI3K; phosphatidylinositide 3-kinase;
Clinical variables and ethnicity may influenced by polymorphism of CAT â262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications
Keywords: T1D; type1 diabetes; CAT; Catalase; MnSOD; manganese superoxide dismutase; SOD; superoxide dismutase; WHO; World Health Organization; TAHINA; survey Transition And Health Impact in North Africa; INSP; National Institute of Public Health; ROS; Reactive oxy
Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review
Keywords: AAV; antineutrophil cytoplasmic antibody associated vasculitis; ACE; angiotensin-converting enzyme; Agt; angiotensin; ANCA; antineutrophil cytoplasmic antibody; AT1R; angiotensin II receptor type 1; AT2R; angiotensin II receptor type 2; CCL2; chemokine C-
Associations of single nucleotide polymorphisms of PTPN22 and Ctla4 genes with the risk of allergic rhinitis in a Chinese Han population
Keywords: PTPN22; CTLA-4; Allergic rhinitis; SNP;
Polimorfismo â1123G>C en el gen PTPN22 y anticuerpos antipéptido citrulinado cÃclico en la artritis reumatoide
Keywords: Artritis reumatoide; PTPN22; ProteÃna linfoide tirosina fosfatasa (Lyp); Anticuerpos antipéptido citrulinado cÃclico; Rheumatoid arthritis; PTPN22; Lymphoid-specific phosphatase (Lyp); Anti-cyclic citrullinated protein antibodies;
Identification of pathogenic genes related to rheumatoid arthritis through integrated analysis of DNA methylation and gene expression profiling
Keywords: RA; rheumatoid arthritis; GEO; Gene Expression Omnibus; DEGs; differentially expressed genes; OA; osteoarthritis; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; HLA-DR; histocompatibility complex, class II, DR; PTPN22; protein tyrosine
HLA-DRB1 alleles and juvenile idiopathic arthritis: Diagnostic clues emerging from a meta-analysis
Keywords: JIA; Juvenile Idiopathic Arthritis; RF; Rheumatoid Factor; ACR; American College of Rheumatology; EULAR; European League Against Rheumatism; ILAR; International League of Associations for Rheumatology; OR; Odds Ratio; HLA; Human Leukocyte Antigens; GWAS;
N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation
Keywords: ABHD4; α/β-hydrolase domain 4; AEA; N-arachidonoylethanolamine; DHEA; N-docosahexaenoylethanolamine; DTEA; N-docosatetraenoylethanolamine; FAAH; fatty acid amide hydrolase; GDE1; glycerophosphodiester phosphodiesterase 1; NAAA; N-acylethanolamine-hydrol
Increased frequency of the PTPN22W* variant in primary Sjogren's Syndrome: Association with low type I IFN scores
Keywords: Sjogren's Syndrome; Type I Interferon; Autoimmunity; Gene polymorphisms; PTPN22;
Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene polymorphism in pulmonary tuberculosis in the Indian population
Keywords: PTPN22; Pulmonary tuberculosis; Single-nucleotide polymorphism;
The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children
Keywords: IL2RA; Polymorphism; PTPN22; T1D;
Association of PTPN22 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population
Keywords: Chronic hepatitis B virus infection; PTPN22; Polymorphism; Susceptibility
Association between KIR gene polymorphisms and rheumatoid arthritis susceptibility: A meta-analysis
Keywords: AS; ankylosing spondylitis; BH; Ben-jamini-Hochberg; 95%CI; 95% confidence interval; CBM; Chinese Biomedical Database; CNKI; Chinese National Knowledge Infrastructure; CTLA4; cytotoxic T-lymphocyte antigen 4; FDR; false discovery rate; HLA-DRB1; human l
Dissecting the role of the foxp3 gene in the joint genetic susceptibility to autoimmune thyroiditis and diabetes: A genetic and functional analysis
Keywords: APS3v; autoimmune polyglandular syndrome type 3; AIRE; autoimmune regulator; AITD; autoimmune thyroiditis; bp; base pair(s); CTLA-4; cytotoxic T-lymphocyte antigen; Î; deletion; dNTP; deoxyribonucleoside triphosphate; FOXP3; Forkhead Box Protein 3; GAPDH
The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus
Keywords: Systemic lupus erythematosus; PTPN22; Tolerance; T follicular helper cells; Autoantibodies; BXSB;
PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner
Keywords: Ptpn22; protein tyrosine phosphatase non-receptor type 22; RIP; rat insulin promoter; LCMV; lymphocytic choriomeningitis virus; CTL; cytotoxic lymphocyte; Treg; T regulatory; WT; wild-type; KO; knockout; T1D; type 1 diabetes; pancLN; pancreatic lymph node
Association of PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with rheumatoid arthritis: A meta-analysis update
Keywords: Meta-analysis; Rheumatoid arthritis; Polymorphism; PTPN22; STAT4; RF; Anti-CCP;
Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease
Keywords: Graves' disease (GD); Histone modifications; Histone acetylation; Peripheral blood mononuclear cells (PBMCs); AS; ankylosing spondylitis; CD40; Cluster of Differentiation 40; CTLA4; CTLcytotoxic T lymphocyte-associated antigen-4; CREBBP; CREB binding prot
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) +1858 C>T gene polymorphism in Egyptian cases with rheumatoid arthritis
Keywords: Rheumatoid arthritis; Polymorphism; PTPN22; Anti-CCP; Gene
Analysis of PTPN22 C1858T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran
Keywords: Type 1 diabetes; PTPN22; Gene polymorphism; Hashimoto’s thyroiditis
A Review of the Genetics of Hypoadrenocorticism
Keywords: hypoadrenocorticism; Addison; genetics; MHC class II; DLA; CTLA4; PTPN22; autoimmunity; adrenal; canine
Contribution of PTPN22, CD28, CTLA-4 and ZAP-70 variants to the risk of type 1 diabetes in Tunisians
Keywords: T1D, Type 1 diabetes; HWE, Hardy–Weinberg equilibrium; OR, odds ratios; LD, linkage disequilibrium, haplotypetype 1 diabetes; ZAP-70; CD28; PTPN22; CTLA-4 genes; Tunisia
Association between the PTPN22 1858C/T gene polymorphism and tuberculosis resistance
Keywords: PTPN22; Polymorphism; Tuberculosis; Brazilian Amazon;
PTPN22 gene polymorphism in Egyptian alopecia areata patients and its impact on response to diphencyprone immunotherapy
Keywords: AA; alopecia areata; PTPN22; protein tyrosine phosphatase N22; DPC; diphenylcyclopropenone; TCR; T cell receptor; SNP; single-nucleotide polymorphism; PCR-RFLP; Polymerase chain reaction Restricted Fragment Length Polymorphism; PTPN22 1858C>T polymorphism
ReviewRoles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity
Keywords: PTPN22; Autoimmunity; Genetic predisposition; Immune tolerance; T regulatory cells (Treg); Autoreactive cells;
The association of PTPN22 polymorphism with endometriosis: effect of genetic and clinical factors
Keywords: PTPN22; ACP1; p53; Endometriosis
Measuring the specific activity of the protein tyrosine phosphatase Lyp
Keywords: PTPN22; Lyp; CD45; Phosphatase activity; Oxidation
Loss of Protein Tyrosine Phosphatase Nonreceptor Type 22 Regulates Interferon-γ-Induced Signaling in Human Monocytes
Keywords: SOCS1; ICAM1; MCP1; Th17; CD; Crohn's disease; ERK; extracellular signal-regulated kinase; IBD; inflammatory bowel disease; ICAM; intracellular adhesion molecule; IFN-γ; interferon γ; IκB; inhibitor of κB; IL; interleukin; Jak; Janus kinase; JNK; c-
Association of the PTPN22 gene (+1858C/T, −1123G/C) polymorphisms with type 1 diabetes mellitus: A systematic review and meta-analysis
Keywords: PTPN22; Polymorphism; Type 1 diabetes mellitus; Meta-analysis
Association of cytotoxic T-lymphocyte associated antigen 4 gene polymorphism with type 1 diabetes mellitus: A meta-analysis
Keywords: CTLA-4; costimulatory molecule cytotoxic T-lymphocyte-associated antigen-4; T1DM; type 1 diabetes mellitus; OR; odds ratio; CI; confidence interval; PTPN22; protein tyrosine phosphatase non-receptor type 22; APC; antigen-presenting cells; HWE; Hardy-Wei
Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?
Keywords: PTPN22; Lyp; Autoimmunity; Phosphatase; Genetics;
Cellular immunity and immunopathology in autoimmune Addison's disease
Keywords: 17OH; steroid cytochrome P450 17-alpha-hydroxylase; 21OH; steroid cytochrome P450 21-hydroxylase; AAD; autoimmune Addison's disease; ACA; adrenal cortex autoantibodies; ADCC; antibody dependent cellular cytotoxicity; AIRE; autoimmune regulator; APC; antig
Association of PTPN22 haplotypes with type 1 diabetes in the Japanese population
Keywords: Type 1 diabetes; PTPN22; Haplotype; Genetic susceptibility
PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy
Keywords: Rheumatoid arthritis; Treatment response; Methotrexate; Genetics; PTPN22
T-cell protein tyrosine phosphatase: A role in inflammation and autoimmunity
Keywords: Cytokine expression; General autoimmunity; Inflammation; PTPN22; Susceptibility; T-cell protein tyrosine phosphate
Genetic regulation of serum cytokines in systemic lupus erythematosus
Keywords: ELISA; enzyme-linked immunosorbent assay; HLA; human leukocyte antigen; IFN-α; interferon-α; MHC; major histocompatibility; mRNA; messenger RNA; OPN; osteopontin; PTPN22; protein tyrosine phosphatase nonreceptor type 22; SLE; systemic lupus erythematosu
Association of PTPN22 C1858T and CTLA-4 A49G polymorphisms with type 1 diabetes in Croatians
Keywords: PTPN22; CTLA-4; Polymorphism; Type 1 diabetes
Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes
Keywords: Autoantibody appearance; Cow's milk formula exposure; Interaction; PTPN22; Type 1 diabetesCM, cow's milk; EIA, enzyme immunoassay; GADA, antibodies to the 65 kD isoform of glutamic acid decarboxylase; IA-2A, antibodies to the protein tyrosine phosphatase-
PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis
Keywords: Acetylcholine receptor; Myasthesia; Gravis; PTPN22
Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant
Keywords: Autoimmunity; LYP; PTPN22; T cell activation; Type 1 diabetes
Genetic polymorphisms in susceptibility to Type 1 Diabetes
Keywords: Type 1 Diabetes; Genetic epidemiology; HLA, INS; CTLA4; PTPN22
Smoking and inflammatory diseases
Keywords: anti-CCP; extra-articular manifestations; lupus; PTPN22; rheumatoid arthritis; shared epitope; smoking