
An overview of the preclinical toxicity and potential carcinogenicity of sitaxentan (Thelin®), a potent endothelin receptor antagonist developed for pulmonary arterial hypertension
Keywords: فشار خون شریانی ریوی; ALP; alkaline phosphatase; ALT; alanaine aminotransferase; APTT; activated partial thromboplastin time; AST; aspartate aminotransferase; AUC; area under the curve; BID; twice daily; BSEP; bile salt export pump; CMC; carboxymethylcellulose; DILI; drug-indu