Synthesis, anticancer activity and DNA-binding properties of novel 4-pyrazolyl-1,8-naphthalimide derivatives
Keywords: پریازول; Naphthalimides; Pyrazole; Anticancer; DNA-binding;
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Bis(3,5-dimethylpyrazole) copper(II) and zinc(II) complexes as efficient initiators for the ring opening polymerization of ε-caprolactone and d,l-lactide
Keywords: پریازول; Pyrazole; Copper; Zinc; Initiators; Ring opening polymerization; ε-Caprolactone; d,l-Lactide
Bimetallic thiocyanate bridged Co(II)-Hg(II) polymers with pyrazole and imidazole ligands
Keywords: پریازول; Cobalt(II)-mercury(II) coordination polymers; Magnetism; Pyrazole; Imidazole; Thiocyanate bridge; Crystal structure;
Chromium coordination compounds with bis(3,5-dimethylpyrazol-1-yl)acetic acid or its anion
Keywords: پریازول; Chromium(III); Pyrazole; Crystal structures; Spectroscopy; Catalysis
The synthesis, characterization and optical properties of novel 5-(3-aryl-1H-pyrazol-5-yl)-2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-1,3,4-oxadiazole
Keywords: پریازول; Pyrazole; Imidazo[1,5-a]pyridine; 1,3,4-Oxadiazole; UV absorption; Fluorescence
Synthesis and biological evaluation of substituted 4,6-diarylpyrimidines and 3,5-diphenyl-4,5-dihydro-1H-pyrazoles as anti-tubercular agents
Keywords: پریازول; RMQMOLWJHBKCMT-UHFFFAOYSA-N; IJBAMVNXGVZYBH-UHFFFAOYSA-N; AHTKDKYBUCQTQU-UHFFFAOYSA-N; FQMJWSOFFQQFQC-UHFFFAOYSA-N; TZQLXLCIFOMNNS-UHFFFAOYSA-N; RALBUVBQCKDLJV-UHFFFAOYSA-N; WGJJESJWIXHLCU-UHFFFAOYSA-N; UUYFUJGLGVGZIP-UHFFFAOYSA-N; CHMAODGGPCMYPS-UHFFFAOY
4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII
Keywords: پریازول; Pyrazole; Benzenesulfonamide; Carbonic anhydrase isoforms I, II, IX, XII; Acetazolamide
Synthesis, characterization and DFT study of a new family of pyrazole derivatives
Keywords: پریازول; β-Diketohydrazone; Pyrazole; X-ray; DFT; Ligand
Substituent’s size in pyrazole derivative ligands as determining factor on nuclearity in Cu(II) complexes
Keywords: پریازول; Copper(II) complexes; Thiazoline; Pyrazole; Crystal structures; Nuclearity
Pyrrole pincers containing imidazole, pyrazole and 1,2,4-triazole groups
Keywords: پریازول; Pincer; Pyrrolyl; Imidazole; Pyrazole; 1,2,4-Triazole; Palladium;
Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents
Keywords: پریازول; Pyrazole; COX-2 inhibitors; Inflammation; Drug design; Molecular modeling
Synthesis and antimicrobial activity of amine linked bis- and tris-heterocycles
Keywords: پریازول; Oxazole; Thiazole; Imidazole; Pyrazole; Antimicrobial activity
Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity
Keywords: پریازول; Pyrazole; 1,3,4-Oxadiazole; COX-2; Anti-inflammatory; Analgesic; Molecular docking analysis
Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl)pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes
Keywords: پریازول; Heteroleptic iridium(III) complex; Polymer light-emitting diode; Ancillary ligand; Carbazole; Pyrazole
Theoretical study on the acidity behavior of some N-methylpyrazole derivatives: CBS-Q method and United Atom (UA) molecular cavity effect
Keywords: پریازول; Pyrazole; CBS-Q; Acidity; Molecular cavity; Atomic radii;
Vapour pressures of 1-methyl derivatives of benzimidazole, pyrazole and indole. The energy of the intermolecular hydrogen bond NH⋯N
Keywords: پریازول; Vapour pressures; 1-Methylbenzimidazole; 1-Methylpyrazole; 1-Methylindole; Imidazole; Benzimidazole; Pyrazole; Enthalpy of sublimation; Entropy of sublimation; Enthalpy of vaporisation; Entropy of vaporisation; Temperature of fusion; Enthalpy of fusion; E
Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAFV600E inhibitors
Keywords: پریازول; BRAFV600E inhibitor; Pyrazole; Niacinamide; Molecular docking; 3D-QSAR;
1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents
Keywords: پریازول; Pyrazole; 1,3,4-Thiadiazole; Thiazolidinone; Thiazole; Anti-inflammatory activity; COX-1 and COX-2; Molecular docking
Antinociceptive effect of 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole. A Celecoxib structural analog in models of pathological pain
Keywords: پریازول; Antinociception; Arthritis; Hyperalgesia; Neuropathy; Pyrazole; Surgery;
Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo[2,1-b]thiazole derivatives bearing pyrazole moieties
Keywords: پریازول; Aminothiazole; Imidazo[2,1-b]thiazole; Pyrazole; Anticancer evaluation; In silico studiesOZSGMUVOGHBQRB-UHFFFAOYSA-N; QESUYMZFVJOPIF-UHFFFAOYSA-N; QGRBTTWTPQCNCG-UHFFFAOYSA-N; PYSJLPAOBIGQPK-UHFFFAOYSA-N; SQRZBYOXRVIMFX-UHFFFAOYSA-N; KIOAMNGRYHTQMH-UHFFFA
Biological activities of novel pyrazolyl hydroxamic acid derivatives against human lung cancer cell line A549
Keywords: پریازول; Pyrazole; Hydroxamic acid; Lung cancer cell; Cell cycle; Autophagy
Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits
Keywords: پریازول; Colitis; Inflammatory bowel disease; Inflammation; Rhizophora apiculata; Anti-oxidant; Pyrazole;
An expeditious and atom-economic synthesis of lead-like, medicinally important 4,5-dihydropyrazolo[1,5-a]pyrazin-6-ones
Keywords: پریازول; Propargylamine; Sonogashira coupling; Ynone; Pyrazole; Intramolecular alkylation; Atom efficiency; Lead-likeness; Privileged structure;
2-(1H-Pyrazol-1-yl)acetic acids as chemoattractant receptor-homologous molecule expressed on Th2 lymphocytes (CRTh2) antagonists
Keywords: پریازول; Pyrazole; CRTh2 antagonists; Structure–activity relationship (SAR)
Novel fluorescent 1,8-naphthalimide derivatives containing thiophene and pyrazole moieties: Synthesis by direct C-H arylation and evaluation of photophysical and electrochemical properties
Keywords: پریازول; Naphthalimide; Thiophene; Pyrazole; C-H arylation; Fluorescence;
Two pyrazolylborate dysprosium(III) and neodymium(III) single ion magnets modeled by a Radial Effective Charge approach
Keywords: پریازول; Single-ion magnets; Lanthanide; Crystal field; Pyrazole; Molecular Magnetism; Single molecule magnets;
Studies on substituted benzo[h]quinazolines, benzo[g]indazoles, pyrazoles, 2,6-diarylpyridines as anti-tubercular agents
Keywords: پریازول; LFUDVFOVNMIIIB-UHFFFAOYSA-N; CTEHHBOBZOCAIT-UHFFFAOYSA-N; JADFRCNEVYMOAL-UHFFFAOYSA-N; AKKATVMDHBEASX-UHFFFAOYSA-N; AYZGFAJCOVMXLA-UHFFFAOYSA-N; YWQRMQADBLJRKZ-UHFFFAOYSA-N; QLIZWGWIQMJGMB-UHFFFAOYSA-N; DSLIJABHAVBSDV-UHFFFAOYSA-N; HJBWBXRSRQEPRF-UHFFFAOY
Identification of a series of 1,3,4-trisubstituted pyrazoles as novel hepatitis C virus entry inhibitors
Keywords: پریازول; Hepatitis C virus; Phenotypic high-throughput screening; Infectious cell culture system; Pyrazole; Entry inhibitor;
SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists
Keywords: پریازول; EP1 antagonist; Pyrazole; Thiazole; Solubility; Optimization;
Catalyst free Michael addition of 3-methyl-2-pyrazolin-5-one to β-nitrostyrenes 'on water': a green protocol for facile synthesis of 4-(1-aryl-2-nitroethyl)-3-methyl-1H-pyrazol-5-ol
Keywords: پریازول; β-Nitrostyrene; pyrazole; 3-Methyl-2-pyrazolin-5-one; Michael addition; Water;
Synthesis of novel pyrazoles incorporating a phenothiazine moiety: unambiguous structural characterization of the regioselectivity in the 1,3-dipolar cycloaddition reaction using 2D HMBC NMR spectroscopy
Keywords: پریازول; Microwave irradiation; Phenothiazine; Pyrazole; Hydrazonyl halides; HMBC; Regioselectivity;
Discovery of pyrazole as C-terminus of selective BACE1 inhibitors
Keywords: پریازول; Alzheimer's disease; BACE1; C-terminus; Click chemistry; In situ screening assay; Pyrazole; EDCl; N-(3-dimethylaminopropyl)-Nâ²-ethylcarbodiimide hydrochloride; HOBt; N-hydroxybenzotriazole; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; E
Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase
Keywords: پریازول; Arylamine N-acetyltransferase; Mycobacterium marinum; Mycobacterium tuberculosis; Pyrazole; Enzyme inhibition; Drug discovery;
Synthesis and bioactivities of some new 1H-pyrazole derivatives containing an aryl sulfonate moiety
Keywords: پریازول; Pyrazole; Enaminone; p-Toluene sulfonyl chloride; Anti-inflammatory activity; COX-2 inhibitors
Structure of bis(nitrato)tetrakis(pyrazole)cobalt(II): Fine tuning in the stabilization of coordination entities by using intramolecular hydrogen bonding
Keywords: پریازول; Cobalt; Copper; Nitrate; Pyrazole; Hydrogen bonding
Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists
Keywords: پریازول; EP1 receptor antagonist; Pyrazole; Thiazole; Overactive bladder; HTS
Rh(III)-catalyzed oxidative synthesis of pyrazoles from azomethines and acrylamides
Keywords: پریازول; Rhodium(III); C-H bond activation; Acrylamide; Azomethine; C-N coupling; Pyrazole
Antifungal activities of amino acid ester functional pyrazolyl compounds against Fusarium oxysporum f.sp. albedinis and Saccharomyces cerevisiae yeast
Keywords: پریازول; Multidentate ligands; Pyrazole; Amino acid ester hydrochlorides; Antifungal activities
Steric hindrance at metal centre quenches green phosphorescence of cationic iridium(III) complexes with 1-(2-pyridyl)-pyrazoles
Keywords: پریازول; Pyrazole; Ligand; Iridium; Complex; Cyclometalation; Phosphorescence
2-(1H-Pyrazol-4-yl)acetic acids as CRTh2 antagonists
Keywords: پریازول; CRTh2; Prostaglandin D2; Antagonist; Pyrazole; Plasma protein binding
Design, synthesis, characterization and biological evaluation of novel pyrazole integrated benzophenones
Keywords: پریازول; Benzophenones; Pyrazole; HMBC; HSQC; COSY; Anti-inflammatory; Antioxidant activity;
Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands
Keywords: پریازول; Heart fatty acid binding protein; FABP3; Pyrazole; Structural design
Pyrazole-based arylalkyne Cathepsin S inhibitors. Part III: Modification of P4 region
Keywords: پریازول; Cathepsin S; Pyrazole; Autoimmune; Alkyne
Synthesis and characterisation of dinuclear Co(II), Ni(II) and Cu(II) unsaturated helical complexes from a novel dipyridyl-bispyrazole ligand
Keywords: پریازول; Helicate; Pyrazole; Dipyridyl; bis-Bidentate ligand; Dinuclear; Co(II); Ni(II); Cu(II)
Novel N-substituted-5-phenyl-1H-pyrazole-4-ethyl carboxylates as potential NLO materials
Keywords: پریازول; Nonlinear optics; Pyrazole; z-Scan
New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents
Keywords: پریازول; 1,2,4-Triazole; Benzoxazole; Pyrazole; Analgesic study; Antimicrobial study
Catecholase activity investigations using in situ copper complexes with pyrazole and pyridine based ligands
Keywords: پریازول; Pyrazole; Catechol; Pyridylpyrazole; Nitrogen heterocycles; Copper; Oxidation reaction
Synthesis and characterization of blue-to-green electrophosphorescence emitter based on pyrazole iridium complexes
Keywords: پریازول; Iridium complex; Triazol; Pyrazole; Electrophosphorescent; Blue-light emitting; Roll-off efficiency
Facile synthesis and characterization of novel pyrazole-sulfonamides and their inhibition effects on human carbonic anhydrase isoenzymes
Keywords: پریازول; Pyrazole; Sulfonamide; Diazonium; Carbonic anhydrase; Inhibition
Mononuclear thiocyanate containing nickel(II) and binuclear azido bridged nickel(II) complexes of N4-coordinate pyrazole based ligand: Syntheses, structures and magnetic properties
Keywords: پریازول; Tetradentate; Pyrazole; Mononuclear; Binuclear; Nickel(II); Structure