Keywords: پیرووات کربوکسیلاز; aPKC; atypical protein kinase C; CBP; CREB binding protein; ChREBP; carbohydrate response element-binding protein; CREB; cAMP response element-binding protein; CRTC2; CREB-regulated transcription coactivator 2; FA; fatty acid; GIPR; glucose-dependent insu
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Keywords: پیرووات کربوکسیلاز; GHSR; Ghrelin; Exercise; Treadmill; Endurance; Food intake; ACC; acetyl coA carboxylase; AMP 5â²; adenosine monophosphate; AMPK; AMP-activated protein kinase; CNS; central nervous system; COX IV; cytochrome c oxidase subunit 4; G6P; glucose-6-phosphatase
Keywords: پیرووات کربوکسیلاز; Pyruvate carboxylase; Diazonium salt; Fast violet B; Oxaloacetate; High throughput screening;
Keywords: پیرووات کربوکسیلاز; Cancer metabolism; Combinatory therapy; Glutaminase isoenzymes; Glutamine; Glutaminase inhibitors; Metabolic reprogramming; DON; 6-diazo-5-oxy-L-norleucine; EATC; Ehrlich ascites tumour cells; ERK; extracellular signal-regulated kinases; GA; glutaminase;
Keywords: پیرووات کربوکسیلاز; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; HLCS; holocarboxylase synthetase; MCD; multiple carboxylase deficiency; CPT1; carnitine palmitoyltransferase 1; ACC2; acetyl-CoA carboxylase 2; PC; pyruvate carboxylase; CPT1R123Cmut; C36
Keywords: پیرووات کربوکسیلاز; ACC; acetyl-CoA carboxylase; CHO; carbohydrates; ChoE; cholesterol esters; DAG; diacylglycerols; G3P; glyceraldehyde 3-phosphate; GL; glycemic load; 11-HETE; 11-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid; 12-HETE; 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraeno
Keywords: پیرووات کربوکسیلاز; aKG; α-ketoglutarate; AA; amino acid; BM; biomass; CCM; central carbon metabolism; CDW; cell dry weight; DNT; Developmental neurotoxicity; ECAR; extracellular acidification rate; ESI; Electrospray ionization; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)ph
Keywords: پیرووات کربوکسیلاز; PC; pyruvate carboxylase; MS; mass spectrometry; Gene knockout; Pyruvate carboxylase (PC); Breast cancer; Cell proliferation rate; Mitochondrial biosynthesis; Cancer biology; Anaplerosis; Mitochondrial metabolism;
Keywords: پیرووات کربوکسیلاز; FBE; Actin free barbed ends; ASC; Apoptosis-associated Speck protein with CARD domain; CT; citrate transporter; ME; cytosolic NADP-dependent malic enzyme; DCF-DA; 2;7-dihydrodichloro-fluorescein diacetate; FAK; focal adhesion kinase; ER; endoplasmic retic
Keywords: پیرووات کربوکسیلاز; Medium-chain triglyceides; Glucose-6-phosphatase; Glutamic alanine transaminase; Pyruvate carboxylase; Arginase
Keywords: پیرووات کربوکسیلاز; ACSS; acetyl-CoA synthetase; ADI; arginine deiminase; AML; acute myeloid leukaemia; AMPK; AMP-activated protein kinase; ALL; acute lymphoblastic leukaemia; ASS; argininosuccinate synthase; BCAAs; branched-chain amino acids; BPTES; bis-2-(5-phenylacetamido
Keywords: پیرووات کربوکسیلاز; Enzyme; Decarboxylation; Biotin; Oxaloacetate decarboxylase; Pyruvate carboxylase
Keywords: پیرووات کربوکسیلاز; Protein biomarker; Pyruvate carboxylase; Exogenous steroid chemicals; Rare minnow;
Keywords: پیرووات کربوکسیلاز; APS; advanced photon source; BC; biotin carboxylase; BCCP; biotin carboxyl carrier protein; BisTris; 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol; CT; carboxyl transferase; LS-CAT; Life Sciences Collaborative Access Team; PC; pyruvate ca
Keywords: پیرووات کربوکسیلاز; RC; respiratory chain; PDH; pyruvate dehydrogenase; BCAAs; branched chain amino acids; CK; creatine kinase; PC; pyruvate carboxylase; PDHc; pyruvate dehydrogenase complex; Primary human mitochondrial disease; Pyruvate dehydrogenase deficiency; Metabolites
Keywords: پیرووات کربوکسیلاز; Ac-CoA; acetyl coenzyme A; GLC; glucose; GLU; glutamate; GLY; glyoxylate; ICIT; isocitrate; MAL; malate; OAA; oxaloacetate; PYR; pyruvate; SUC; succinate; α-KG; α-oxoglutarate; GDH; glutamate dehydrogenase; ICDH; isocitrate dehydrogenase; ICL; isocitrat
Keywords: پیرووات کربوکسیلاز; ACC; acetyl-CoA carboxylase; ACL; ATP:citrate lyase; ACP; acyl-carrier protein; AGPase; ADP-glucose pyrophosphate; AOX; acyl-CoA oxidase; ARA; arachidonic acid; BE; branching enzymes; CDP-DAG; CDP-diacylglycerol; DAG; diacylglycerol; DGAT; diacylglycerol
Double silencing of relevant genes suggests the existence of the direct link between DNA replication/repair and central carbon metabolism in human fibroblasts
Keywords: پیرووات کربوکسیلاز; P; primase (product of the PRIM gene); D; DNA polymerase ι (product of the POLI gene); L; ligase IV (product of the LIG4 gene); T; topoisomerase (DNA) IIIβ (product of the TOP3B gene); ACO; aconitase; ALDO; fructose-bisphosphate aldolase; CS; citrate sy
Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
Keywords: پیرووات کربوکسیلاز; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho
Artesunate-induced mitophagy alters cellular redox status
Keywords: پیرووات کربوکسیلاز; ACADVL; very long-chain specific acyl-CoA dehydrogenase; ACC; acetyl-CoA carboxylase 1; ATP; adenosine triphosphate, vacuolar-type H+-ATPase (V-ATPase); COX â
£; cytochrome c oxidase IV; CPS; carbamoyl-phosphate synthase; CQ; chloroquine; GSH; glutathione
Kaempferol ameliorates hyperglycemia through suppressing hepatic gluconeogenesis and enhancing hepatic insulin sensitivity in diet-induced obese mice
Keywords: پیرووات کربوکسیلاز; Kaempferol; Flavonoid; Insulin resistance; Type 2 diabetes; Gluconeogenesis; Pyruvate carboxylase;
Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction
Keywords: پیرووات کربوکسیلاز; ACMG; American College of Medical Genetics and Genomics; ALT; Alanine aminotransferase; CADD; Combined Annotation Dependent Depletion; MAF; Minor allele frequency; OAA; Oxaloacetate; PC; Pyruvate carboxylase; PEP; Phosphoenolpyruvate; PEPCK; Phosphoenolpy
Regular articleSite-saturation engineering of proline 474 in pyruvate carboxylase from Rhizopus oryzae to elevate fumaric acid production in engineered Saccharomyces cerevisiae cells
Keywords: پیرووات کربوکسیلاز; Pyruvate carboxylase; Fumaric acid; Saccharomyces cerevisiae; Site-saturation engineering;
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors
Keywords: پیرووات کربوکسیلاز; 3-NPA; 3-nitropropionic acid; Co; complex; FH; fumarate hydratase; PC; pyruvate carboxylase; TCA cycle; tricarboxylic acid cycle; SDH; succinate dehydrogenase; 3-nitropropionic acid (PubChem CID: 1678); Atpenin A5 (PubChem CID: 54676868); rotenone (PubChe
Inhibition of pyruvate carboxylase by 1α,25-dihydroxyvitamin D promotes oxidative stress in early breast cancer progression
Keywords: پیرووات کربوکسیلاز; 1α,25-dihydroxyvitamin D; Breast cancer; Prevention; Oxidative stress; Metabolism; Pyruvate carboxylase;
Cloning and characterization of pyruvate carboxylase gene responsible for calcium malate overproduction in Penicillium viticola 152 and its expression analysis
Keywords: پیرووات کربوکسیلاز; Amp; ampicillin; bp; base pair; TCA; tricarboxylic acid cycle; rRNA; ribosomal ribonucleic acid; rDNA; ribosomal deoxyribonucleic acid; ITS; the internal transcribed spacer; gDNA; genomic deoxyribonucleic acid; CSL; corn steep liquor; kb; kilobase; MS; ma
28-Homocastasterone down regulates blood glucose, cholesterol, triglycerides, SREBP1c and activates LxR expression in normal & diabetic male rat
Keywords: پیرووات کربوکسیلاز; 28-Homocastasterone; Blood glucose; Cholesterol; Triglyceride; Liver x Receptor; 28-HC; 28-homocastasterone; LxR; Liver x Receptor; ABCT; ATP-binding cassette transporters; SREBP1c; sterol regulatory element binding protein-1c; TNF-α; Tumor necrosis fact
Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling
Keywords: پیرووات کربوکسیلاز; ACC; Acetyl-coA carboxylase; ACOX1; Acyl-CoA oxidase1; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; DTSSP; 3,3â²-Dithiobis (sulfosuccinimidylpropionate); FABP1; Fatty acid binding protein 1; FASN; Fatty acid synthase; FCCP; Carbonyl c
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle
Keywords: پیرووات کربوکسیلاز; CAT; catalase; COX; cytochrome c oxidase; DJ7; Parkinson 7; DNM1L; dynamin-1-like protein; FIS1; mitochondrial fission protein 1; MFF; mitochondrial fission factor; MFN1; mitofusin-1; MFN2; mitofusin-2; mtDNA; mitochondrial DNA; mtNOD; C57BL/6NTac-mtNODLt
Reconstruction of a genome-scale metabolic model and in silico analysis of the polymalic acid producer Aureobasidium pullulans CCTCC M2012223
Keywords: پیرووات کربوکسیلاز; Biopolymers; Metabolic engineering; Pyruvate carboxylase; Reducing equivalents;
Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance
Keywords: پیرووات کربوکسیلاز; StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine
Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence
Keywords: پیرووات کربوکسیلاز; IGF1; insulin like growth factor 1; IR; insulin resistance; MCP; monocrotophos; OPI; organophosphorus insecticide; GSIS; glucose sensitive insulin secretion; PC; pyruvate carboxylase; mG3PDH; mitochondrial glycerol-3-phosphate dehydrogenase; MDH; malate d
Metabolic engineering of CHO cells to alter lactate metabolism during fed-batch cultures
Keywords: پیرووات کربوکسیلاز; CHO cells; Pyruvate carboxylase; Metabolic engineering; Fed-batch; Monoclonal antibody;
Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis
Keywords: پیرووات کربوکسیلاز; Multiple sclerosis; Biotin; Promyelinogenic agent; Virtual hypoxia; ACC; acetyl-CoA carboxylase; AMN; adrenomyeloneuropathy; BBB; blood-brain barrier; BTBGD; biotin-thiamine responsive basal ganglia disease; EDSS; Expanded Disability Status Scale; HLCS;
Candidate biomarkers for mosquito age-grading identified by label-free quantitative analysis of protein expression in Aedes albopictus females
Keywords: پیرووات کربوکسیلاز; Longevity; Proteomics; Hexamerin; Glutathione-S transferase; Pyruvate carboxylase; Insect cuticle protein;
Cod liver oil ameliorates sodium nitrite-induced insulin resistance and degradation of rat hepatic glycogen through inhibition of cAMP/PKA pathway
Keywords: پیرووات کربوکسیلاز; Food additives; Fructose 1,6-diphosphatase; Glycogen phosphorylase; Glycogen synthase; Phosphodiesterase; Pyruvate carboxylase;
Metabolic engineering of Propionibacterium freudenreichii subsp. shermanii for enhanced propionic acid fermentation: Effects of overexpressing three biotin-dependent carboxylases
Keywords: پیرووات کربوکسیلاز; Propionic acid fermentation; Propionibacteria; Metabolic engineering; Methylmalonyl-CoA carboxyltransferase; Methylmalonyl-CoA decarboxylase; Pyruvate carboxylase
Exploiting the metabolism of PYC expressing HEK293 cells in fed-batch cultures
Keywords: پیرووات کربوکسیلاز; HEK293 cells; Pyruvate carboxylase; Fed-batch; Recombinant protein
Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells
Keywords: پیرووات کربوکسیلاز; AMPK; AMP-activated protein kinase; CHOP; C/EBP homologous protein; CPT-1; Carnitine palmitate transferase-1; DAG; diacylglycerol; ER; endoplasmic reticulum; Eto; etomoxir; FAO; fatty acid oxidation; HG/PA; high glucose/palmitate; JNK; C-Jun N-terminal ki
Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes
Keywords: پیرووات کربوکسیلاز; HMG-CoA synthase; hydroxymethylglutaryl-CoA synthase; IBMX; isobutylmethylxanthine; IGFR; insulin-like growth factor receptor; IPS 1; inositol-3-phosphate synthase 1; IRS; insulin receptor substrate; myo-inositol; 1D-myo-inositol 3-phosphate; PCB; pyruvat
Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity
Keywords: پیرووات کربوکسیلاز; Enzyme; Biotin; Decarboxylation; Pyruvate carboxylase; Transcarboxylase; Oxaloacetate decarboxylase
The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: Has it been overlooked?
Keywords: پیرووات کربوکسیلاز; AAT; aspartate aminotransferase; ANT; adenine nucleotide transporter; Asp; aspartate; Asp/Glu; aspartate glutamate transporter; αKG; alpha-ketoglutarate; αKGT; alpha-ketoglutarate transporter; CIC; citrate isocitrate transporter; cytAAT; cytosolic aspar
Fumaric acid production in Saccharomyces cerevisiae by simultaneous use of oxidative and reductive routes
Keywords: پیرووات کربوکسیلاز; Saccharomyces cerevisiae; Fumaric acid; Oxidative and reductive routes; Pyruvate carboxylase; Carbon/nitrogen ratio;
Hepatocyte nuclear factor 4α regulates the expression of the murine pyruvate carboxylase gene through the HNF4-specific binding motif in its proximal promoter
Keywords: پیرووات کربوکسیلاز; ChIP; chromatin immunoprecipitation; DR1; direct repeat 1; EMSA; electrophoretic mobility shift assay; FBPase; fructose-1,6-bisphosphatase; G6Pase; glucose-6-phosphatase; HIP1; housekeeping initiator protein 1; HNF4α; hepatocyte nuclear factor 4 alpha; M
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases
Keywords: پیرووات کربوکسیلاز; Sirtuins; SIRT4; C. elegans; Biotin-dependent carboxylase; Pyruvate carboxylase; Protein acetylation;
Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype
Keywords: پیرووات کربوکسیلاز; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; aP2-Ucp1 mice; transgenic mice expressing UCP1 gene from the aP2 gene promoter; AA; arachidonic acid; ATM; adipose tissue macrophages; BAT; brown adipose tissue; BCAA; branched-chain amino a
Metabolic engineering of Lactobacillus plantarum for succinic acid production through activation of the reductive branch of the tricarboxylic acid cycle
Keywords: پیرووات کربوکسیلاز; Succinic acid; Lactobacillus plantarum; Metabolic engineering; Pyruvate carboxylase; Phosphoenolpyruvate carboxykinase; Malic enzyme
Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells
Keywords: پیرووات کربوکسیلاز; Insulinoma cells; shRNA; Pyruvate carboxylase; Fatty acid synthase; Phospholipids; Cholesterol esters; Lipid remodeling
Short communication: Genetic differences between New Zealand and North American dairy cows alter milk production and gluconeogenic enzyme expression1
Keywords: پیرووات کربوکسیلاز; pyruvate carboxylase; genetic selection; concentrate supplementation;
Metabolic profiling of a Rhizopus oryzae fumaric acid production mutant generated by femtosecond laser irradiation
Keywords: پیرووات کربوکسیلاز; 3PG; 3-phosphoglyceric acid; 5-ALA; 5-aminolevulinic acid; AcCoA; acetyl-CoA; ALA; alanine; ASN; asparagine; ASP; aspartic acid; ATP; adenosine triphosphate; CIT; citric acid; CYS; cysteine; DCW; dry cell weight; EMP; Embden-Meyerhof-Parnas; FUM; fuma