دانلود مقالات ISI درباره Rapa + ترجمه فارسی

اثر دوزهای بالینی مرتبط با داروهای ضد سرطان بر سلول های بنیادی مزانشیمی انسانی

The effect of clinically relevant doses of immunosuppressive drugs on human mesenchymal stem cells

Keywords: AT; adipose tissue; BM; bone marrow; CsA; cyclosporine A; COX-2; cyclooxygenase-2; DEX; dexamethasone; DMEM; Dulbeccós modified Eaglés medium; DMSO; dimethyl sulfoxide; ELISA; enzyme-linked immunosorbent assay; FasL; Fas ligand; HGF; hepatocyte growth f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

تأثیر برنامه ریزی متابولیکی بر عملکرد سلولی دندریتیک

The impact of metabolic reprogramming on dendritic cell function

Keywords: AGE; advanced glycation end products; AICAR; 5-Aminoimidazole-4-carboxamide ribonucleotide; AMPK; 5′ adenosine monophosphate-activated protein kinase; APC; antigen-presenting cell; Atg7; autophagy-related gene 7; ATP; adenosine triphosphate; ATRA; all-t

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

یک کارآزمایی کنترل تصادفی برای ایجاد امکان پذیری و ایمنی درمان رپامایسین در گروه انسانی انسانی: عملکرد ایمنی، عملکرد فیزیکی و اثرات شناختی

A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects

Keywords: ALK PHOS; alkaline phosphatase; ALT; alanine aminotransferase (serum glutamate-pyruvate transaminase (SGPT)); AST; aspartate aminotransferase (serum glutamic oxaloacetic transaminase (SGOT)); BUN; blood urea nitrogen; CA; calcium; CI; confidence interval;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

مهار رامامیسین هدف پستانداران آسیب زودرس مغز را از طریق مدولاسیون قطبش میکروگلالیال پس از خونریزی سواراخنووییدی تجربی در موش صحرایی

Inhibition of mammalian target of rapamycin attenuates early brain injury through modulating microglial polarization after experimental subarachnoid hemorrhage in rats

Keywords: mTOR; mammalian target of rapamycin; EBI; early brain injury; SAH; subarachnoid hemorrhage; SD; Sprague-Dawley; BBB; blood-brain barrier; aSAH; aneurysmal subarachnoid hemorrhage; ICP; increasing intracranial pressure; CBF; cerebral blood flow; PI3K; phos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

داربست عصب محیطی بیونیک با پوشش آهسته با رپامایسین موجب بازسازی عصب سیاتیک موش پس از آسیب می شود

Slow-releasing rapamycin-coated bionic peripheral nerve scaffold promotes the regeneration of rat sciatic nerve after injury

Keywords: Tissue engineering; Scaffold; RAPA; Peripheral nerve; PLGA; Slow-releasing

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ارزیابی گزارش فعالیت بدنی در برنامه های مداخله شیوه زندگی پیشگیری از دیابت در جامعه: یک بررسی منظم

Evaluation of physical activity reporting in community Diabetes Prevention Program lifestyle intervention efforts: A systematic review

Keywords: CDC; Centers for Disease Control and Prevention; CHAMPS; Community Healthy Activities Model Program for Seniors; CVD; Cardiovascular Disease; DPP; Diabetes Prevention Program; DPRP; Diabetes Prevention Recognition Program; DVD; digital versatile disk; IPA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

قرار گرفتن در معرض اسید فورفوروکاتنیک سبب استرس تناسلی اندوپلاسمی در کبد می شود و اثرات آن توسط 4-فنیل بوتیرات بهبود می یابد

Perfluorooctanoic acid exposure induces endoplasmic reticulum stress in the liver and its effects are ameliorated by 4-phenylbutyrate

Keywords: PFOA; perfluorooctanoic acid; ER stress; endoplasmic reticulum stress; 4-PBA; sodium 4-phenylbutyrate; ROS; reactive oxygen species; Cat; catalase; Sod1; superoxide dismutase 1; Sod2; superoxide dismutase 2; Sesn1; sestrin 1; LC3; microtubule-associated p

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

تنظیم کراتین 8/18 متابولیسم گلوکز در سلول های کبدی عادی و سرطانی با استفاده از مداخله دیفرانسیلی از وضعیت هگزوکیناز و سیگنالینگ انسولین

Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling

Keywords: HCC; hepatocellular carcinoma; K; keratin; IF; intermediate filament; G6P; glucose-6-phosphate; HK; hexokinase; GK; glucokinase; VDAC; voltage-dependent anion channel; GS; glycogen synthase; PI3K; phosphatidylinositol-3 kinase; GSK-3β; glycogen synthase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

d-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions

Keywords: d-gal; d-galactose; LECs; lens epithelial cells; HCQ; hydroxychloroquine; ROS; reactive oxygen species; VADC; voltage dependent anion channel; mPTP; mitochondria permeability transition pore; MMP; mitochondrial membrane potential; NAC; N-acetylcysteine; G

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Maternal exposure to di-n-butyl phthalate (DBP) promotes epithelial-mesenchymal transition via regulation of autophagy in uroepithelial cell

Keywords: DBP; di-n-butyl phthalate; EEDs; environmental endocrine disruptors; PND; postnatal day; BW; body weight; EMT; epithelial-mesenchymal transition; AR; androgen receptor; PUECs; primary urethral epithelial cells; T; testosterone; SD; standard deviation; ATG

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells

Keywords: PF; paeoniflorin; OA; okadaic acid; 3-MA; 3-methyladenine; Rapa; rapamycin; LiCl; lithium chloride; AD; Alzhiemer's disease; CAST; Ac-calpastain; CQ; chloroquine; NFTs; neurofibrillary tangles; CaMKII; calcium/calmodulin protein kinase II; MAP2; microtu

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1

Keywords: Thermogenesis; UCP1; Kinases; βAR; β-adrenergic receptor; 8-Br-cAMP; 8-Bromoadenosine 3′,5′-cyclic monophosphate; 8-Br-cGMP; 8-Bromoguanosine 3′,5′-cyclic monophosphate; Akt; protein kinase B; ANP; Atrial natriuretic peptide; BNP; B-type natriur

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells

Keywords: 3-MA; 3-methyladenine; CQ; Chloroquine; Rapa; Rapamycin; EBSS; Dulbecco's Phosphate-Buffered Saline; ATG5; Autophagy-related 5; MAP1LC3/LC3; Microtubule-associated protein 1 light chain 3; mTOR; Mammalian (or mechanistic) Target of Rapamycin; SQSTM1; sequ

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Acrolein induces NLRP3 inflammasome-mediated pyroptosis and suppresses migration via ROS-dependent autophagy in vascular endothelial cells

Keywords: AS; atherosclerosis; CVD; cardiovascular diseases; ROS; reactive oxygen species; HUVECs; human umbilical vein endothelial cells; LPS; lipopolysaccharide; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazo- lium bromide; DMSO; dimethyl sulfoxide; NAC;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy contributes to 4-Amino-2-Trifluoromethyl-Phenyl Retinate-induced differentiation in human acute promyelocytic leukemia NB4 cells

Keywords: AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; ATPR; 4-Amino-2-Trifluoromethyl-Phenyl Retinate; 3-MA; 3-methyladenine; RAPA; rapamycin; ATO; arsenic trioxide; siRNA; small interfering RNA; MDC; monodansylcad

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

OP16, a novel ent-kaurene diterpenoid, potentiates the antitumor effect of rapamycin by inhibiting rapamycin-induced feedback activation of Akt signaling in esophageal squamous cell carcinoma

Keywords: Akt; protein kinase B; DMSO; dimethyl sulfoxide; ESCC; esophageal squamous cell carcinoma; FBS; fetal bovine serum; IC50; half maximal inhibitory concentration; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol 3 kinase; Rapa; rapamycin; Rap

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription

Keywords:  + S; With serum;  − S; Without serum; CHX; Cycloheximide; DMEM; Dulbecco's modified Eagle's medium; ECL; Enhanced chemiluminescence; ETS; Externally transcribed spacer; Exp; Exponentially growing cells; FBS; Fetal bovine serum; h; Hour; LY; LY29400

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation

Keywords: AMPK; 5′ adenosine monophosphate-activated protein kinase; BSA; bovine serum albumin; CQ; chloroquine; EC; endothelial cell; eIF2α; eukaryotic translation initiation factor 2α; ER; endoplasmic reticulum; Erk1/2; extracellular signal-regulated kinase;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Modulating angiogenesis with integrin-targeted nanomedicines

Keywords: (RGD)m; RGD mimetics; 4-NQO; 4-nitroquinoline 1-oxide; AAA; Abdominal Aortic Aneurysms; ADA; 8-Amino-3,6-Dioxaoctonoic Acid; AH-GDM; Aminohexyl-Geldanamycin; ami; Amide; AP-2α; Activating Protein 2α; ARMS; Alveolar Rhabdomyosarcoma; ATO; Arsenic Trioxid

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Triggering autophagic cell death with a di-manganese(II) developmental therapeutic

Keywords: γH2AX; phosphorylated H2AX histone; caspase; cysteine-dependent asparate-specific proteases CAT, catalase; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; Dox; doxorubicin; DSB; double strand breaks; LC-3; microtubule associated protein 1 light weight c

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages

Keywords: AAPH; 2,2′-azobis (2-amidinopropane) dihydrochloride; AMPK; AMP-activated protein kinase; ComC; compound C; Edar; edaravone; 3-MA; 3-methyladenine; MMP; mitochondrial membrane potential; Rapa; rapamycin; Resv; trans-resveratrol; VitC; vitamin C; Autopha

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Interplay between mTOR and STAT5 signaling modulates the balance between regulatory and effective T cells

Keywords: Tregs; regulatory T cells; Teffs; effective T cells; Rapa; Rapamycin; miR-155; micro-RNA 155; Regulatory T cell; mTOR signaling; STAT5 signaling; MicroRNA-155; Immune balance; Rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagic flux determination in vivo and ex vivo

Keywords: ATP; adenosine triphosphate; BBB; blood brain barrier; BRB; blood retinal barrier; BGT; BSA/glycine/Triton X-100; BSA; bovine serum albumin; CNS; central nervous system; DABCO; 1,4-diazabicyclo[2.2.2]octane; DAPI; 4,6-diamidino-2-phenylindole dihydrochlor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Clinically-relevant cyclosporin and rapamycin concentrations enhance regulatory T cell function to a similar extent but with different mechanisms: An in-vitro study in healthy humans

Keywords: Tregs; regulatory T cells; CsA; cyclosporin A; RAPA; rapamycin; MPA; mycophenolic acid; PBMCs; peripheral blood mononuclear cells; FoxP3; forkhead box protein 3; MLR; mixed lymphocyte reaction; MFI; mean fluorescence intensity.; Cyclosporine; FoxP3; Immun

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Chronic obstructive pulmonary disease self-management activation research trial (COPD-SMART): Results of recruitment and baseline patient characteristics

Keywords: COPD; chronic obstructive pulmonary disease; SMART; self-management activation research trial; UC; usual care; PASM; physical activity self-management; CRQ; Chronic Respiratory Questionnaire; 6MWD; six-minute walk distance; 6MWT; six-minute walk test; SD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Identification, sequencing and comparative analysis of pBp15.S plasmid from the newly described entomopathogen Bacillus pumilus 15.1

Keywords: Bacillus pumilus plasmid; Virulence factors; Rep; RapA; RapAB; Small rolling circle plasmid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Keywords: Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive companion of mTOR; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; m-TORC2; mTOR complex 2; Sp1; specific protein 1; MTH; mithramycin; RAPA; rapamycin; ChIP; chromat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Regular ArticleNMDA receptor blockade in the developing cortex induces autophagy-mediated death of immature cortical GABAergic interneurons: An ex vivo and in vivo study in Gad67-GFP mice

Keywords: aCSF; artificial cerebrospinal fluid; EGFP; enhanced green fluorescent protein; FITC; fluoroisothiocyanate; LDH; lactate dehydrogenase; NADH; β-nicotinamide adenine dinucleotide; MFI; mean fluorescence intensity; PFA; paraformaldehyde; RAPA; rapamycin; R

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo

Keywords: Rapa; rapamycin; ELPs; elastin-like polypeptides; FKBP; FK506 binding protein 12; mTOR; mammalian target of rapamycin; ITC; inverse transition cycling; CMT; critical micelle temperature; CMC; critical micelle concentration; DLS; dynamic light scattering;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase

Keywords: TERT; telomerase reverse transcriptase; mTOR; mechanistic target of rapamycin; S6K; p70 S6 kinase; 4E-BP1; 4E-binding protein 1; eIF4; eukaryotic initiation factor 4; PI3K; phosphoinositide 3-kinase; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-l-propane

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells

Keywords: Cyps; cyclophilins; FKBPs; immunophilin; FKBP52; FK506 binding protein (52); ER; rough endoplasmic reticulum; SERCA2b; sarco-endoplasmic Ca2 +-ATPase isotype 2b; IP3R II; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potential channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome

Keywords: Rapa; rapamycin; SjS; Sjögren's syndrome; ELP; Elastin like-Polypeptide; FSI; FKBP-S48I48; CATS; cathepsin S; NOD; Non obese diabetic mouse; LG; lacrimal gland; mTOR; mammalian target of Rapamycin; SG; salivary gland; CMT; critical micelle temperature; T

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Structure and function of RapA: A bacterial Swi2/Snf2 protein required for RNA polymerase recycling in transcription

Keywords: RapA; Bacterial Swi2/Snf2; RNA polymerase recycling; Structure of Swi2/Snf2; Transcription complex remodeling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Vascular Profile Characterization of Liver Tumors by Magnetic Resonance Imaging Using Hemodynamic Response Imaging in Mice

Keywords: CE-MRI; contrast-enhanced MRI; CRLM; colorectal liver metastasis; fMRI; functional MRI; Gd-DTPA; gadolinium-diethylene-triaminepenta-acetate; HCC; hepatocellular carcinoma; HPF; high-power microscopic fields; HRI; hemodynamic response imaging; MRI; magnet

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of gastric hormones by systemic rapamycin

Keywords: GI; gastrointestinal tract; mTOR; mammalian target of rapamycin; Rapa; rapamycin; S6; ribosomal protein S6; Gastric mTOR; Gastric endocrine cells; Gastric hormones;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

Keywords: HCC; Hepatocellular carcinoma; VEGF; vascular endothelial growth factor; BEV; Bevacizumab; mTOR; mammalian target-of-rapamycin; p70S6K; p70S6 kinase; RPS6; ribosomal S6 protein; 4EBP1; eukaryotic initiation factor 4E-binding protein 1; RAPA; rapamycin; IP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Baohuoside-1 inhibits activated T cell proliferation at G1-S phase transition

Keywords: APCs; antigen presenting cells; B1; baohuoside-1; CsA; cyclosporin A; Con A; concanavalin A; cdks; cyclin-dependent kinases; EBV; Epstein-Barr virus; IC50; 50% inhibitory concentration; FK506; tacrolimus; FACS; fluorescence activated cell sorting; Ig; i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Estrogen receptor α and β subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells

Keywords: AP-1; activating protein 1; CsA; cyclosporin A; CYP40; cyclophilin of 40 kDa; DMEM; Dulbecco's modified eagle medium; E2; estradiol; ER; estrogen receptor; ERE; estrogen responsive element; ERKO; Estogen Receptor Knock-Out; FCS; fetal calf serum; FK; FK5

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Desensitization protocols improving access and outcome in transplantation

Keywords: ABO incompatible transplantation; Desensitization; Double filtration plasmapheresis; HLA-specific antibody; Intravenous immunoglobulin (IVIg); Plasmapheresis; Sensitization; Transplantation; ABO-DSA; antibody to donor ABO antigens; ABOi; ABO incompatible;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2005 سفارش ترجمه