Keywords: Encapsulin nanocompartments; Surface display; Cargo encapsulation; Protein-based nanoparticle carrier; Rational vaccine design; T. maritima; Thermotoga maritima; E. coli; Escherichia coli; GFP; Green Fluorescence Protein; M2e; Matrix2 protein ectodomain;
مقالات ISI (ترجمه نشده)
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Keywords: CFU; colony forming unit; fMLF; N-formylmethionine-leucyl-phenylalanine; GFP; Green Fluorescent Protein; MOI; multiplicity of infection; PI; propidium iodide; PMN; polymorphonuclear leukocyte; RFU; relative fluorescence units; SA; Staphylococcus aureus; S
Keywords: Whey protein; In vitro digestion; Bioactive peptide; Glucagon-like peptide-1; Dipeptidyl peptidase IV inhibitor; Antioxidant activity; α-LA; α-lactalbumin; β-LG; β-lactoglobulin; ABAP; 2,2â²-azobis(2-methylpropionamidine) dihydrochloride; AMC; H-Gly-
Keywords: α-MEM; (alpha-modified Eagle's minimum essential medium); Ail; (attachment-invasion locus); BPW; (buffered peptone water); E-64; (L-trans-epoxysuccinyl-L-leucylamido(4-guanidino)butane); LC-MS/MS; (liquid chromatography coupled to tandem mass spectrome
Keywords: ccpA; catabolite control protein A; celA; cellobiose-specific phosphor-β-glucosidase; cre; catabolite-responsive element; ELISA; enzyme-linked immunosorbent assay; GFP; green fluorescent protein; LAB; lactic acid bacteria; LB; Luria-Bertani media; noxE;
Keywords: CA; caprylic acid; mAb; monoclonal antibody; Ig; immunoglobulin; HCP; host cell protein; CHO; Chinese hamster ovary; LC; light chain; HC; heavy chain; MCBS; multi-component buffer system; TCID50; 50% tissue culture infectious dose; MuLV; murine leukemia v
Keywords: CV; cell viability; DLS; dynamic light scattering; DOPE; 1,2-dioleyl-sn-glycero-3-phosphoethanolamine; DPPE; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; eGFP; enhanced green fluorescent protein; EtBr; ethidium bromide; FBS; fetal bovine serum; GAGs;
Keywords: PolyQ; Polyglutamine; Htt; Huntingtin; Httex1; Htt Exon 1; HD; Huntington's disease; PulSA; Pulse Shape Analysis; i; Cells With Inclusions; ni; Cells With Diffuse Httex1; RFU; Relative Fluorescence Units; IPA; Ingenuity Pathway Analysis; FDR; False Discov
Keywords: Cell viability assay; Calcein AM; Sytox Orange; Retinal cell line; Fluorescence assay; Plate reader; 7kCHOL; 7-ketocholesterol; ABCB1; ATP-binding cassette sub-family B member 1 (P-glycoprotein); ABCC1; ATP-binding cassette sub-family C member 1 (Multidru
Keywords: CM; conditioned medium; OCCs; ovarian cancer cells; CPD; cumulative number of population doublings; Cx43; connexin 43; H2O2; hydrogen peroxide; HGF; hepatocyte growth factor; HPMCs; human peritoneal mesothelial cells; JC-1; 5,5',6,6'-tetrachloro-1,1',3,3'
Keywords: Piperazine derivatives; MTT assay; α1A blocking activity; Pharmacokinetics; BPH; Benign prostatic hyperplasia; T; testosterone; DHT; dihydrotestosterone; SARM; selective androgen receptor modulator; PSA; prostate specific antigen; MTT; 3-(4, 5-dimethylth
Keywords: DNA damage; Elimination reactions; Abasic site; Artificial nuclease; High-throughput screen; AP; Apurinic/Apyrimidinic Site; APE1; Apurinic/Apyrimidinic Endonuclease 1; BER; Base Excision Repair; Fpg; Formamidopyrimidine DNA glycosylase; FITC; Fluorescein
Keywords: BAC; benzalkonium chloride; MGHS40; macrogolglycerol hydroxystearate; PS80; polysorbate 80; HCE-T; human corneal epithelial cell line; HBSS; Hank⿿s balanced salt solution; DPBS; Dulbecco⿿s phosphate buffered saline; DAPI; 4⿲,6-Diamidino-2-phenylindo
Keywords: BBB; blood-brain barrier; CNS; central nervous system; hPSCs; human pluripotent stem cells; BMECs; brain microvascular endothelial cells; P-gp; P-glycoprotein; RA; retinoic acid; UM; unconditioned medium; EC; endothelial cell; ECÂ +Â RA medium; EC mediu
Keywords: PA; palmitic acid; TNF-α; tumor necrosis factor alpha; NFκB; nuclear factor-kappa B; OXA; orexin A/hypocretin 1; OX1R; orexin receptor 1; OX2R; orexin receptor 2; IL-6; interleukin 6; LPS; lipopolysaccharide; TLR-4; toll like receptor 4; RT-PCR; real ti
Keywords: AIF; apoptosis-inducing factor; BSO; Buthionine sulfoximine; CAM; chorioallantoic membrane; cIAP; cellular inhibitor of apoptosis; DR5; death receptor-5; ENDOG; endonuclease G; ER; endoplasmatic reticulum; FCS; fetal calf serum; HBV; hepatitis B virus; HC
Keywords: a.u.; arbitrary units; CC; point of charge compensation; Chol; cholesterol; CLSM; confocal laser scanning microscopy; CV; cell viability; DLS; dynamic light scattering; DOPC; 1,2-di-[(9Z)-octadec-9-enoyl]-sn-glycero-3-phosphocholine; DOPE; 1,2-dioleoyl-sn
Keywords: DMEM; Dulbecco's Modified Eagle's Medium; MEM; Minimum Essential Medium; FBS; fetal bovine serum; RFU; relative fluorescence units; RM-ANOVA; repeated measures analysis of variance; NADPH; nicotinamide adenine dinucleotide phosphate (reduced form); NADH;
Keywords: TTFL; transcriptional/translational feedback loops; PRDX1-6; Peroxiredoxins 1-6; HaCaT; human adult low calcium temperature keratinocytes; L2N; Lists Two Network Software; nHPLC-MS/MS; nano liquid chromatography and mass spectrometry proteomic analysi
Keywords: DMPC; dimyristoylphosphatidylcholine; DMPE; dimyristoylphosphatidylethanolamine; DMPS; dimyristoylphosphatidylserine; SEM; scanning electron microscopy; DSC; differential scanning calorimetry; MLVs; multilamellar vesicles; LUVs; large unilamellar vesicles
Keywords: AbX; antibody with mostly fucosylated glycans; AbX-AF; antibody with completely afucosylated glycans; ADCC; antibody-dependent cell-mediated cytotoxicity; AICC; antibody-independent cell-mediated cytotoxicity; CV; coefficient of variation; EC50; half maxi
Keywords: EV; extracellular vesicle; LC-MS; liquid chromatography coupled to mass spectrometry; MP; microparticle; ALT; alanine transaminase; CES; carboxylesterase; MVB; multivesicular body; LPS; lipopolysaccharide; galN; d-galactosamine; AMRT; accurate mass meas
Keywords: αVβ3; alphaV beta3; αVβ5; alphaV beta5; AA; allylamine; β-APN; β-aminoproprionitrile; DAPI; diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagle's Medium; DPBS; Dulbecco's phosphate buffered saline; EC; endothelial cells; ECGS; endothelia
Keywords: ABC; ATP-binding cassette; ANPs; acyclic nucleoside phosphonates; BCRP/ABCG2; breast cancer resistance protein; CNTs; concentrative nucleoside transporters; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; hCNT2; human con
Hypericin affects cancer side populations via competitive inhibition of BCRP
Keywords: ABC transporters; ATP-binding cassette transporters; ALDH; aldehyde dehydrogenase; BCRP; breast carcinoma resistance protein; CDH1; cadherin 1 gene encoding E-cadherin; CSLCs; cancer stem-like cells; DEAB; N,N-diethylaminobenzaldehyde; EDTA; ethylenediami
Trichomonas vaginalis cathepsin D-like aspartic proteinase (Tv-CatD) is positively regulated by glucose and degrades human hemoglobin
Keywords: AP; aspartic proteinase; CatD; cathepsin D; GR; glucose restriction; Hb; hemoglobin; HG; high glucose; HIBS; heat inactivated bovine serum; PREs; protease-resistant extracts; RFU; relative fluorescence unit; SEPs; secretion/excretion products; TCA; trichl
Novel indanone derivatives as MAO B/H3R dual-targeting ligands for treatment of Parkinson's disease
Keywords: Multi-targeting; Neurodegenerative diseases; Histamine H3 receptor antagonist; Monoamine oxidase inhibitor; Neurotransmitter dysregulation; Parkinson's disease; AChE; acetylcholinesterase; anal. calc.; elementary analysis calculated; BuChE; butyrylcholine
Impact of calcium-sensitive dyes on the beating properties and pharmacological responses of human iPS-derived cardiomyocytes using the calcium transient assay
Keywords: Human stem cell cardiomyocytes; Calcium fluorescent dye; Calcium transient; Preclinical cardiac safety; Amp; amplitude; bpm; beats per minute; BR; beat rate; CiPA; Comprehensive in Vitro Proarrhythmia Assay; CTD; calcium transient duration; DMSO; dimethyl
Duplex recombinase polymerase amplification assays incorporating competitive internal controls for bacterial meningitis detection
Keywords: Bacterial meningitis; Recombinase polymerase amplification; Duplex; CSF; cerebrospinal fluid; PCR; polymerase chain reaction; POC; point-of-care; LAMP; loop-mediated isothermal amplification; HDA; helicase dependant amplification; RPA; recombinase polymer
Culture of human neurospheres in 3D scaffolds for developmental neurotoxicity testing
Keywords: CD-Link; crosslinker; DNT; developmental neurotoxicity; EGF; epidermal growth factor; FGF; fibroblast growth factor; G'; storage modulus; G"; loss modulus; Maleimide-PVA; maleimide-polyvinylalcohol; MeHgCl; methylmercury chloride; NPCs; neural progenitor
In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairment
Keywords: Aβ; amyloid beta; AChE; acetyl cholinesterase; AD; Alzheimer's disease; AG; aminoguanidine; AGEs; advanced glycation end products; ANOVA; analysis of variance; AU; arbitrary units; BSA; bovine serum albumin; d-gal; d-galactose; DNP; Donepezil; GSH; red
Chikungunya virus inhibition by peptidomimetic inhibitors targeting virus-specific cysteine protease
Keywords: Chikungunya virus; nsP2 protease; Protease inhibitor; FRET assay; Peptidomimetic compounds; Antiviral assay; CHIKV-Specific inhibitor; CHIKV; Chikungunya virus; CHIKF; Chikungunya fever; CHIKV nsP2pro; Chikungunya nsP2 protease; ORF; Open reading frame; M
Muscle-protective effects of Schisandrae Fructus extracts in old mice after chronic forced exercise
Keywords: ANOVA; analysis of variance; A1R; adenosine A1 receptor; CAT; Catalase; DEXA; dual energy X-ray absorptiometry; DW; distilled water; GSH; Glutathione; HE; haematoxylin and eosin; HNE; hydroxynonenal; iNOS; inducible nitric oxide synthase; LDH; lactate deh
Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease
Keywords: PK; pharmacokinetics; DMF; N,N,-dimethylfornamide; DCM; dichloromethane; CDI; carbonyl diimidazole; TLC; thin layer chromatography; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; N-hydroxybenzotriazole; DIEA; diisopropylethylamine; DTT; dithio
Valorization of the whole grains of Triticum aestivum L. and Triticum vulgare L. through the investigation of their biochemical composition and in vitro antioxidant, anti-inflammatory, anticancer and anticalpain activities
Keywords: Wheat species; Phytochemical composition; Antioxidant activities; Anti-calpain activity; EMEM; Eagle's Minimal Essential Medium.; FBS; Fetal Bovine Serum.; MTT; Methylthiazolyldiphenyl-tetrazolium bromide.; RRLC; Rapid Resolution Liquid Chromatography.;
Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10
Keywords: Aβ; amyloid-beta peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; CoQ10; Coenzyme Q10; DCF; 2â²,7â²-dichlorofluorescein; DIC; differential interference contrast; H2DCFDA; 2â²-7â²-dichlorofluorescin diacetate; HBSS; Hank's Balanced Sa
AmTAR2: Functional characterization of a honeybee tyramine receptor stimulating adenylyl cyclase activity
Keywords: Behavior; Biogenic amines; Cellular signaling; GPCR; Honeybee; Second messenger; HA; hemagglutinin A; GPCR; G protein-coupled receptor; n.a.; not applicable; RFU; relative fluorescence units; TM; transmembrane;
EphB2 signaling-mediated Sirt3 expression reduces MSC senescence by maintaining mitochondrial ROS homeostasis
Keywords: Eph; Ephrin receptor; Sirt; sirtuin; MnSOD; mitochondrial localized superoxide dismutase 2; UCB-MSC; umbilical cord blood derived mesenchymal stem cell; mtROS; mitochondrial reactive oxygen species; NT; non-targeting; siRNA; small interference ribose nucl
Cyanobacteria as source of marine bioactive compounds: Molecular specific detection based on Î9 desaturase gene
Keywords: DW; dry weight; ELISA; Enzyme Linked Immunosorbent Assay; DNA; Desoxyribonucleic acid; UV; Ultraviolet; BLAST; Basic Local Alignment Search Tool; NCBI; National Center for Biotechnology Information; DPPH; 2,2-diphenyl-1-picrylhydrazyl; BHT; Butylated hydr
Measuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay
Keywords: Dopamine transporter; Norepinephrine transporter; Serotonin transporter; Fluorescent monoamine substrate; Designer drugs; Drug screening; 2C-B; 2,5-dimethoxy-4-bromophenethylamine; 4-FA; 4-fluoroamphetamine; 5-APB; 5-(2-aminopropyl)benzofuran; 25B-NBOMe;
The ABCG2 efflux transporter from rabbit placenta: Cloning and functional characterization
Keywords: ABCG2/BCRP efflux transporter; Placenta barrier; Rabbit; developmental toxicity testing; Active drug transport; MDCKII in vitro model; ABCG2; ATP-binding cassette sub-family G member 2; cDNA; complementary DNA; DMEM; Dulbecco's modified Eagle's medium; d
Evaluation of in vitro storage characteristics of cold stored platelet concentrates with N acetylcysteine (NAC)
Keywords: CD62P expression; Refrigerated concentrates; N acetylcysteine; Sialidase activity; Storage; 4-MU-NeuAc; 2'-(4-methylumbelliferyl)- N-acetylneuraminic acid; GSH; glutathione; MoAb; monoclonal antibodies; NAC; N acetyl-L-cysteine; NO; nitric oxide; PCs; pla
Gamma-irradiation produces active chlorine species (ACS) in physiological solutions: Secoisolariciresinol diglucoside (SDG) scavenges ACS - A novel mechanism of DNA radioprotection
Keywords: 2-AP; 2-aminopurine; ACS; active chlorine species; ANOVA; analysis of variance; APF; 3â²-(p-aminophenyl) fluorescein; Cl; chlorine atom; Clâ; Â chloride anion; Cl2; chlorine; Cl2â; Â dichloro radical anion; ClOâ; Â hypochlorite ion; H2O2; hydrogen
Characterization of Cimex lectularius (bedbug) defensin peptide and its antimicrobial activity against human skin microflora
Keywords: Bed bug; Defensin; Antimicrobial peptide; Insect antimicrobial peptides; Skin microflora; Antibacterial assay; Circular dichroism; DiSC(3)5 assay; EC50 assay; EC50; half maximal effective concentration; MIC; minimum inhibitory concentration; CFU; colony f
Antimicrobial activity of mosquito cecropin peptides against Francisella
Keywords: Tularemia; Francisella; Mosquitoes; Antimicrobial peptides; Innate immunity; Depolarization; EC50; half maximal effective concentration; MIC; minimum inhibitory concentration; CFU; colony forming units; RFU; Relative fluorescence units; DiSC3(5); 3, 3â²-
Ability of the marine bacterium Pseudomonas fluorescens BA3SM1 to counteract the toxicity of CdSe nanoparticles
Keywords: NPs; nanoparticles; CdSe NPs; cadmium-selenium colloidal nanocrystals; NP3; cadmium-selenium colloidal nanocrystals of 3Â nm in diameter; NP8; cadmium-selenium colloidal nanocrystals of 8Â nm in diameter; TOPO; trioctylphosphine oxide; ODPA; octadecylphos
Ischemic conditions and β-secretase activation: The impact of membrane cholesterol enrichment as triggering factor in rat brain endothelial cells
Keywords: CNS; central nervous system; AD; Alzheimer's disease; RBE4; rat brain endothelial cell line; OGD; oxygen and glucose deprivation; ogR; oxygen and glucose Restoration; BACE1; amyloid precursor protein (APP) β-secretase; PSEN1; presenilin-1; Aβ; amyloid p
Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets
Keywords: Phytochemicals; Cancer prevention; Reactive oxygen species; DNA damage; DNA adduct; Heterocyclic amines; AOPI; acridine orange/propidium iodide; BRCA-1; breast cancer 1 early onset; CAT; catalase; DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DEP
Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B
Keywords: VWBVATUTVWMVIR-LJAQVGFWSA-N; ATG4B; autophagin 1; FRET; fluorescence resonance energy transfer; HTS; high throughput screening; LC3B; microtubule-associated protein 1 A/B light chain 3B; NEM; N-ethylmaleimide; LC-MS; liquid chromatography coupled mass s
Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1
Keywords: 4-Di-1-ASP; 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide; CsA; Cyclosporine A; primary hPT; human primary proximal tubule cells; MATE; multidrug and toxin extrusion proteins; OAT; organic anion transporter; OATP; organic anion polypeptide transpo