دانلود مقالات ISI درباره میانگین انحراف مربع ریشه + ترجمه فارسی

Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold

Keywords: میانگین انحراف مربع ریشه; 2-Arylbenzo[b]furan derivatives; Xanthine oxidase inhibitor; Antioxidant; Molecular docking; XO; xanthine oxidase; ROS; reactive oxygen species; SARs; structure-activity relationships; DPPH; 1,1-diphenyl-2-picrylhydrazyl; RMSD; root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment

Keywords: میانگین انحراف مربع ریشه; A2AAR; adenosine receptor A2A; AUC; area under curve; β2AR; beta 2 adrenergic receptor; D3R; dopamine receptor D3; δOR; delta-opioid receptor; ECL; extracellular loop; GPCR; G protein-coupled receptor; H1R; histamine receptor H1; ICL; intracellular loop

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

UvrB protein of Corynebacterium pseudotuberculosis complements the phenotype of knockout Escherichia coli and recognizes DNA damage caused by UV radiation but not 8-oxoguanine in vitro

Keywords: میانگین انحراف مربع ریشه; BER; base excision repair; BLAST; Basic Local Alignment Search Tool; DOPE; Discrete Optimized Protein Energy; NER; nucleotide excision repair; PDB; Protein Data Bank; Rg; radio of gyration; RMSD; root mean square deviation; RNS; reactive nitrogen species;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Intrinsic structural versatility of the highly conserved 412-423 epitope of the Hepatitis C Virus E2 protein

Keywords: میانگین انحراف مربع ریشه; HCV; Hepatitis C Virus; E2; envelope glycoprotein 2; CD81; Cluster of Differentiation 81; ThT; Thioflavin T; PDB; Protein Data Bank; mAb; monoclonal Antibodies; Fab; antigen-binding fragment; MD; molecular dynamics; RMSD; root mean square deviation; RMSIP

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of structure and function of mitochondrial alcohol dehydrogenase isozyme III from Komagataella phaffii GS115

Keywords: میانگین انحراف مربع ریشه; ADH; alcohol dehydrogenase; KpADH3; mitochondrial alcohol dehydrogenase isozyme III from Komagataella phaffii GS115; ACS1; the acetyl‑CoA synthetase; SGD; Saccharomyces Genome Database; ScADH1; alcohol dehydrogenase I from Saccharomyces cerevisiae; SsAD

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

αCGRP, another amyloidogenic member of the CGRP family

Keywords: میانگین انحراف مربع ریشه; CGRP; Calcitonin Gene Related Peptide; CT; calcitonin; IAPP; islet amyloid polypeptide; GPCR; G-Protein Coupled Receptor; RAMP; Receptor Activity Modifying Protein; T2D; Type 2 Diabetes; MTC; Medullary Thyroid Carcinoma; MD; Molecular Dynamics; CD; Circul

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection

Keywords: میانگین انحراف مربع ریشه; TmArgBP; wild-type Arginine Binding Protein isolated from Thermotoga maritima; TmArgBP20-233; residues 20-233 of TmArgBP; D1; domain 1 of TmArgBP; D2; domain 2 of TmArgBP; SBP; substrate binding protein; RMSD; root mean square deviation; RMSF; root me

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Lipid metabolism potential and mechanism of CPe-III from chickpea (Cicer arietinum L.)

Keywords: میانگین انحراف مربع ریشه; HFD; high-fat diet; HDL; high-density lipoprotein; LDL; low-density lipoprotein; VLDL; very low-density lipoprotein; CETP; cholesteryl ester transfer protein; CE; cholesteryl ester; RCT; reverse cholesterol transport; MD; molecular dynamics; TC; total cho

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms

Keywords: میانگین انحراف مربع ریشه; AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Presence of a consensus DNA motif at nearby DNA sequence of the mutation susceptible CG nucleotides

Keywords: میانگین انحراف مربع ریشه; TS; tumor suppressor; DNMT1; DNA methyltransferase 1; NTDs; nucleotides; AAs; amino acids; RMSD; root mean square deviation; MD; molecular dynamics; HB; hydrogen bond; PWM; position weight matrix; Mutation; Epigenetics; CpG islands; Tumor suppressors; Onc

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

The role of d-allo-isoleucine in the deposition of the anti-Leishmania peptide bombinin H4 as revealed by 31P solid-state NMR, VCD spectroscopy, and MD simulation

Keywords: میانگین انحراف مربع ریشه; H2; bombinin H2; H4; bombinin H4; d-allo-Ile; d-allo-isoleucine; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocholine; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DOPI; 1,2-dioleoyl-sn-glycero-3-phosphoinositol; DOPS; 1,2-dioleoyl-sn-glycero-3-phosphos

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

E7 oncoprotein of human papillomavirus: Structural dynamics and inhibitor screening study

Keywords: میانگین انحراف مربع ریشه; HPV; Human papillomavirus; pRB; Phosphorylated Retiboblastoma; 3D; Three dimensional; MoRFs; Molecular recognition features; DNA; Deoxyribo nucleic acid; CRs; Conserved regions; IDPs; Intrinsically disordered proteins; CD-HIT; Cluster database at high ide

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Modeling, dynamics and phosphoinositide binding of the pleckstrin homology domain of two novel PLCs: η1 and η2

Keywords: میانگین انحراف مربع ریشه; Pleckstrin homology domain; Phosphoinositide binding; Molecular modeling; Docking; MD simulation; PLC; Phospholipase C; PHη1; PH domain of PLCη1; PHη2; PH domain of PHη2; IP3; inositol-(1,4,5)-triphosphate; IP4; Inositol-(1,3,4,5)-tetrakisphosphate; u

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

The L530R variation associated with recurrent kidney stones impairs the structure and function of TRPV5

Keywords: میانگین انحراف مربع ریشه; TRPV5; Ca2+-selective channel; Kidney stone; L530R variation; Membrane interaction; TRPV5; transient receptor potential cation channel vanilloid subfamily member 5; TM; transmembrane; cRNA; capped complementary RNA; MD; molecular dynamics; RMSD; root mean

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

The ternary complex structure of d-mandelate dehydrogenase with NADH and anilino(oxo)acetate

Keywords: میانگین انحراف مربع ریشه; d-mandelate dehydrogenase; 2-Ketopantoate reductase; Domain motion; Substrate specificity; Crystal structure; AOA; anilino(oxo)acetate; d-2-HydDH; d-2-hydroxyacid dehydrogenase; KPR; 2-ketopantoate reductase; d-ManDH; d-mandelate dehydrogenase; MES; 2-(N-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Solution structure of human steroidogenic acute regulatory protein STARD1 studied by small-angle X-ray scattering

Keywords: میانگین انحراف مربع ریشه; Steroidogenic acute regulatory protein; Solution structure; Small-angle X-ray scattering; Hydrodynamic properties; Cholesterol; BSA; bovine serum albumin; CD; circular dichroism; EOM; ensemble optimization method; MBP; Maltose-Binding Protein; MD; molecul

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid

Keywords: میانگین انحراف مربع ریشه; Clostridium perfringens; Neuraminidase; NanI; CHES; Anti-neuraminidase agents; Crystal structure; CpNanI; Clostridium perfringens neuraminidase NanI; Neu5Ac; N-acetylneuraminic acid; CHES; 2-(cyclohexylamino)ethanesulfonic acid; SpNanB; Streptococcus pneu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations

Keywords: میانگین انحراف مربع ریشه; Molecular dynamics simulation; KCNH1 channel; Ion binding sites; Y464A mutant; Na+ binding sites; C-type inactivation; Cryo-EM; Cryo-electron microscopy; SF; selectivity filter; MD; molecular dynamics simulation; EAG; ether-à-go-go; TMD; transmembrane do

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Prediction of a highly deleterious mutation E17K in AKT-1 gene: An in silico approach

Keywords: میانگین انحراف مربع ریشه; SNP; Single nucleotide polymorphism; RMSD; Root mean square deviation; AKT1; Signaling pathways; SNP; in silico; Deleterious;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW

Keywords: میانگین انحراف مربع ریشه; M20 metallopeptidase; LysK; Amino-group carrier protein; Crystal structure; Thermus thermophilus; AAA; α-aminoadipate; PDB; Protein Data Bank; r.m.s.d.; root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Flaviviridae viruses use a common molecular mechanism to escape nucleoside analogue inhibitors

Keywords: میانگین انحراف مربع ریشه; Flaviviridae; Virus; Polymerase; Analogue; Interrogating; Water; CMA; 2'-C-methyladenosine; CMA-TP; 2'-C-methyladenosine Triphosphate; CPUs; Computer-Processing Units; HCV; Hepatitis C Virus; JEV; Japanese Encephalitis Virus; NTP; Nucleoside Triphosphate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A combined biochemical and computational studies of the rho-class glutathione s-transferase sll1545 of Synechocystis PCC 6803

Keywords: میانگین انحراف مربع ریشه; GST; glutathione S-transferase; GSH; reduced glutathione; CuOOH; cumene hydrogen peroxide; Non-Se-GPX; non-selenium dependent glutathione peroxidase; RMSD; root mean square deviation; RMSF; root mean square fluctuation; ED; essential dynamics; PCA; princi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Electron transfer pathways analysis of oxygen tolerant [NiFe]-hydrogenases for hydrogen production: A quantum mechanics/molecular mechanics - statistical coupled analysis

Keywords: میانگین انحراف مربع ریشه; [NiFe]-hydrogenase; QM/MM; Molecular dynamics; Statistical coupled analysis; MBed; Maxwell-Boltzmann energy distribution; MD; Molecular Dynamics; PCA; Principal Component Analysis; QM/MM; Quantum Mechanics/Molecular Mechanics; RMSD; Root Mean Square Devia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticlePharmacophore based 3D-QSAR modeling, virtual screening and docking for identification of potential inhibitors of β-secretase

Keywords: میانگین انحراف مربع ریشه; BACE1; β-secretase; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood brain barrier; PDB; protein data bank; rmsd; root mean square deviation; IC50; inhibitory concentration; β-secretase; Alzheimer's disease; Pharmacophore; Virtual screening; Doc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structure and biochemistry of phenylacetaldehyde dehydrogenase from the Pseudomonas putida S12 styrene catabolic pathway

Keywords: میانگین انحراف مربع ریشه; Styrene monooxygnease; Phenylacetaldehyde dehydrogenase; Structure; Kinetics; ALDH; aldehyde dehydrogenase; ALDH1; sheep liver cytosolic aldehyde dehydrogenase; ALDH2; bovine mitochondrial aldehyde dehydrogenase; BME; β-mercaptoethanol; CoA; coenzyme A;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Systematic prioritization of functional hotspot in RIG-1 domains using pattern based conventional molecular dynamic simulation

Keywords: میانگین انحراف مربع ریشه; RIG-1; Retinoic acid inducible gene 1; CARD; Caspase activation and recruitment domain; HEL; Helicase domain; RD; Repressor domain; DO; Distant ortholog; RMSD; Root mean square deviation; RMSF; Root mean square fluctuation; RIG-1; Motif; Distant ortholog;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Exploration of interaction zones of β-tubulin colchicine binding domain of helminths and binding mechanism of anthelmintics

Keywords: میانگین انحراف مربع ریشه; GTP; Guanosine triphosphate; RMSD; Root mean square deviation; RCSB; Research Collaboratory for Structural Bioinformatics; HBA; Hydrogen bond acceptor; Anthelmintics; β-tubulin; Colchicine; Structure-based model; Pharmacophore; Docking; Nematode;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

MODCSA-CA: A multi objective diversity controlled self adaptive cuckoo algorithm for protein structure prediction

Keywords: میانگین انحراف مربع ریشه; MODCSA; multi objective diversity controlled self adaptive; CA; cuckoo algorithm; CS; cuckoo search; PDB; Protein Data Bank; IMMALG; Immune Algorithm; I-PAES; inspired Pareto archived evolutionary strategy; HGA; Hybrid Genetic Algorithm; MODE-P; multi-obj

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

In silico characterization of TTHA0596: A potential Zn2 + binding protein of ATP-binding cassette transporter

Keywords: میانگین انحراف مربع ریشه; APBS; adaptive Poisson Boltzmann solver; ATP; ATP-binding cassette; Fe; iron; HP; hypothetical protein; Mn; manganese; MSA; multiple sequence alignment; NBD; nucleotide binding domain; ORF; open reading frame; PMBP; periplasmic metal binding protein; RMSD

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Performance of a docking/molecular dynamics protocol for virtual screening of nutlin-class inhibitors of Mdmx

Keywords: میانگین انحراف مربع ریشه; EF; enrichment factor; FP; fluorescence polarization; LIE; linearized interaction energy; MM/PBSA; molecular mechanics/poisson - Boltzmann surface area; NPT; number, pressure-temperature; NTD; N-terminal transactivation domain; RMSD; root mean square de

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors

Keywords: میانگین انحراف مربع ریشه; GK; guanylate kinase; VL; visceral leishmaniasis; GMPK; guanosine monophosphate kinase; 5GP; 5′-guanylic acid; GOLD; genetic optimization for ligand docking; CHARMM; chemistry of HARvard molecular mechanics; BLAST; basic local alignment search tool; PDB

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Insights into the molecular basis for substrate binding and specificity of the fungal cystine transporter CgCYN1

Keywords: میانگین انحراف مربع ریشه; TMD; transmembrane domain; APC; amino acid-polyamine-organocation; WT; wild type; S.D.; synthetic defined; RMSD; root mean square deviation; Cystine transporter; Yeast; xCT; Substrate binding; APC superfamily; Homology modeling;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring putative inhibitors of Death Associated Protein Kinase 1 (DAPK1) via targeting Gly-Glu-Leu (GEL) and Pro-Glu-Asn (PEN) substrate recognition motifs

Keywords: میانگین انحراف مربع ریشه; DAPK1; Death Associated Protein Kinase 1; NMDARs; N-methyl-D-aspartate receptors; NMDAR2A or NR2A; N-methyl-D-aspartate receptor subtype 2A; NMDAR2B or NR2B; N-methyl-D-aspartate receptor subtype 2B; NSC; neuronal survival-signaling complex; NDC; neuronal

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

RElative QUantitation Inferred by Evaluating Mixtures (REQUIEM)

Keywords: میانگین انحراف مربع ریشه; Relative quantitation; Precision; Accuracy; Mass spectrometry; RNA-Seq; ES; embryonic stem (cells); GC-FID; gas chromatography with flame ionization detection; HPAEC-PAD; high performance anion exchange chromatography with pulsed amperometric detection; R

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-proliferative effects of copper(II) complexes with hydroxyquinoline-thiosemicarbazone ligands

Keywords: میانگین انحراف مربع ریشه; Thiosemicarbazone; Copper(II) complex; 8-Hydroxyquinoline; Proliferation; ROS; Anticancer; ATCUN; amino-terminal copper and nickel binding; CD; circular dichroism; DMF; dimethylformamide; DMSO; dimethyl sulfoxide; Dien; diethylenetriamine; EDTA; ethylened

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin

Keywords: میانگین انحراف مربع ریشه; Lectin; Seleno-sugar; Fucose; Affinity; Phase determination; Crystal structure; AOL; fucose-specific lectin from Aspergillus oryzae; AAL; fucose-specific lectin from Aleuria aurantia; AFL; fucose-specific lectin from Aspergillus Fumigatus; α-Se-Fuc; α-s

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Production of a soluble single-chain variable fragment antibody against okadaic acid and exploration of its specific binding

Keywords: میانگین انحراف مربع ریشه; Okadaic acid; CLEIA; Single-chain variable fragment; Binding complex; OA; okadaic acid; DSP; diarrhetic shellfish poisoning; ELISA; enzyme-linked immunosorbent assay; scFv; single-chain variable fragment; CDR; complementarity-determining region; PDB; Prot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71

Keywords: میانگین انحراف مربع ریشه; HFMD; hand, foot and mouth disease; 3Cpro; 3C proteinase; EV71; enterovirus 71; HRV; human rhinovirus; NMR; nuclear magnetic resonance; RP-HPLC; reverse phase-high pressure liquid chromatography; TFA; trifluoroacetic acid; LC; liquid chromatography; MS; m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Bupropion and its photoreactive analog (±)-SADU-3-72 interact with luminal and non-luminal sites at human α4β2 nicotinic acetylcholine receptors

Keywords: میانگین انحراف مربع ریشه; Human α4β2 nicotinic acetylcholine receptor; Bupropion; (±)-SADU-3-72; Molecular docking; Luminal and non-luminal sites; Ca2+ influx; AChR; nicotinic acetylcholine receptor; NCA; noncompetitive antagonist; (±)-BP; (±)-bupropion [(±)-2-(tert-butylami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Gypsy moth pheromone-binding protein-ligand interactions: pH profiles and simulations as tools for detecting polar interactions

Keywords: میانگین انحراف مربع ریشه; Gypsy moth; Olfaction; Ligand interactions; Pheromone-binding protein; Homology modeling; pH profile of ligand binding; (−)-Dis; (−)-disparlure = (7S, 8R)-epoxy-2-methyloctadecane; (+)-Dis; (+)-disparlure = (7R, 8S)-epoxy-2-methyloctadecane; ANOVA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T

Keywords: میانگین انحراف مربع ریشه; Primary hyperoxaluria type I; Human alanine glyoxylate aminotransferase; Interface hot spots; Protein dimerization; Molecular dynamics; Protein mistargeting; AGT-Mi; minor allele of human alanine glyoxylate aminotransferase; PH1; Primary Hyperoxaluria typ

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors

Keywords: میانگین انحراف مربع ریشه; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; HPRT; hypoxanthine phosphoribosyltransferase; APRT; adenosine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; v

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Spatial patterns and cell surface clusters in perineuronal nets

Keywords: میانگین انحراف مربع ریشه; PNN; perineuronal nets; CNS; central nervous system; CSPG; chondroitin sulfate proteoglycans; AMPA receptor; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; WFA; Wisteria floribunda agglutinin; GalNAc; N-acetyl-galactosamine; CS; chondroit

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells

Keywords: میانگین انحراف مربع ریشه; Microtubule; βI-tubulin; Paclitaxel; Drug resistance; Molecular dynamics simulation; Free energy landscape; WT; wild type; MT; mutant type; Ptxl; paclitaxel; MD; molecular dynamics; PCA; principle component analysis; FEL; free energy landscape; RMSD; roo

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions

Keywords: میانگین انحراف مربع ریشه; ATP; adenosine triphosphate; β-ODAP; β-N-oxalyl-L-α,β-diaminopropionic acid; DMOG; dimethyloxalylglycine; 1,4 DPCA; 1,4-dihydrophenonthrolin-4-one-3-carboxylic acid; D-ODAP; β-N-oxalyl-D-α,β-diaminopropionic acid; DTT; dithiothreitol; EDTA; ethylen

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular interaction of δ-conopeptide EVIA with voltage-gated Na+ channels

Keywords: میانگین انحراف مربع ریشه; COSY; correlation spectroscopy; DG; distance geometry; DIEA; N,N-diisopropylethylamine; Fmoc; 9-fluorenylmethoxycarbonyl; GSH; glutathione reduced; GSSG; glutathione oxidized; HBTU; O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyl-uronium-hexafluorophospha

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights

Keywords: میانگین انحراف مربع ریشه; SDF-1; stromal cell-derived factor 1; GPCR; G protein-coupled receptor; CNS; central nervous system; NS; nervous system; DRG; dorsal root ganglion; OPC; oligodendrocyte precursor cell; MS; multiple sclerosis; PDB; Protein Data Bank; TM; transmembrane; EL;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

A multi-subunit based, thermodynamically stable model vaccine using combined immunoinformatics and protein structure based approach

Keywords: میانگین انحراف مربع ریشه; APC; antigen presenting cells; CTL; cytolytic T-lymphocytes; FASTA; FAST-ALL; HBHA; heparin-binding hemagglutinin; HTL; helper T-lymphocytes; IC50; inhibitory concentration; IEDB-AR; immune epitope database analysis resource; JCAT; Java Codon Adaptation T

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis

Keywords: میانگین انحراف مربع ریشه; OleP; 8.8a-deoxyoleandolide epoxigenase; P450; cytochrome P450; EpoK; Epothilone C-D monooxygenase; PimD; Pimaricin monooxygenase; MycG; Mycinamicin monooxygenase; CLT; clotrimazole; KC; ketoconazole; DMSO; dimethyl sulfoxide; DEO; 8.8a-deoxyoleandolide

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Structural and biochemical characterization of bacterial YpgQ protein reveals a metal-dependent nucleotide pyrophosphohydrolase

Keywords: میانگین انحراف مربع ریشه; HD; histidine-aspartate; (d)NTP; (deoxy)ribonucleoside triphosphate; bsYpgQ; Bacillus subtilis YpgQ; dNTP; deoxyribonucleoside triphosphate; NTP; ribonucleoside triphosphate; dNMP; deoxyribonucleoside monophosphate; Pi; inorganic monophosphate; PPi; inorg

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه