دانلود مقالات ISI درباره میانگین انحراف مربع ریشه + ترجمه فارسی

Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis

Keywords: میانگین انحراف مربع ریشه; OleP; 8.8a-deoxyoleandolide epoxigenase; P450; cytochrome P450; EpoK; Epothilone C-D monooxygenase; PimD; Pimaricin monooxygenase; MycG; Mycinamicin monooxygenase; CLT; clotrimazole; KC; ketoconazole; DMSO; dimethyl sulfoxide; DEO; 8.8a-deoxyoleandolide

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages

Keywords: میانگین انحراف مربع ریشه; ADME; absorption, distribution, metabolism, and excretion; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EMSA; Electrophoretic Mobility Shift Assay; Erk; extracellular-signal-related kinase; FBS; foetal bovine serum; GAPDH; glyce

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Structural insight into activation of homoserine dehydrogenase from the archaeon Sulfolobus tokodaii via reduction

Keywords: میانگین انحراف مربع ریشه; HSD; homoserine dehydrogenase; Tris; tris(hydroxymethyl)aminomethane; PDB; Protein Data Bank; Tricine; N-[tris(hydroxymethyl)methyl]glycine; Bis-tris; 2,2-bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol; HEPES; [4-(2-hydroxyethyl)-1-piperazinyl] ethanesu

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the reliability of the maximum entropy method for reconstructing 3D and 4D NOESY-type NMR spectra of proteins

Keywords: میانگین انحراف مربع ریشه; CS; compressed sensing; FT; Fourier transform; IRLS; iteratively reweighted least-squares; IST; iterative soft thresholding; MaxEnt; maximum entropy; MDD; multi-dimensional decomposition; QME; quantitative maximum entropy; RMSE; root mean square error; RM

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Structural alterations by five disease-causing mutations in the low-pH conformation of human dihydrolipoamide dehydrogenase (hLADH) analyzed by molecular dynamics - Implications in functional loss and modulation of reactive oxygen species generation by pa

Keywords: میانگین انحراف مربع ریشه; LADH; (dihydro)lipoamide dehydrogenase; PDHc; pyruvate dehydrogenase complex; α-KGDHc; alpha-ketoglutarate dehydrogenase complex; ROS; reactive oxygen species; RMSD; root mean square deviation; FAD; flavin adenine dinucleotide; NAD+/NADH; nicotinamide ad

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

High-resolution structures of the d-alanyl carrier protein (Dcp) DltC from Bacillus subtilis reveal equivalent conformations of apo- and holo-forms

Keywords: میانگین انحراف مربع ریشه; CP; carrier protein; Dcp; d-alanyl CP; ACP; acyl CP; PCP; peptidyl CP; ArCP; aryl CP; ppant; 4′-phosphopantetheine; FA; fatty acid; PK; polyketide; NRP; non-ribosomal peptide; SeMet; selenomethionine; rmsd; root mean square deviation; Carrier protein; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research paperMolecular principles behind Boceprevir resistance due to mutations in hepatitis C NS3/4A protease

Keywords: میانگین انحراف مربع ریشه; HCV; hepatitis C virus; MD; molecular dynamics; RMSD; root mean square deviation; RMSF; root mean square fluctuation; Rg; radius of gyration; VMD; visual molecular dynamics; HCV; Molecular dynamics; Simulations; Boceprevir; Resistance; Mutants;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A structural model for FOXRED1, an FAD-dependent oxidoreductase necessary for NADH: Ubiquinone oxidoreductase (complex I) assembly

Keywords: میانگین انحراف مربع ریشه; CPS; carbamoyl phosphate synthase; DAO; d-amino acid oxidase; DMGDH; dimethylglycine dehydrogenase; DMGO; dimethylglycine oxidase; FOXRED; FAD-dependent oxidoreductase; HADHA; hydroxyacyl dehydrogenase; MDH; malate dehydrogenase; MSOX; monomeric sarcosine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

β-Lactoglobulin interactions with local anaesthetic drugs - Crystallographic and calorimetric studies

Keywords: میانگین انحراف مربع ریشه; LA; local anaesthetic; TET; tetracaine; PRM; pramocaine (pramoxine); LG; lactoglobulin; BLG; bovine β-lactoglobulin; GLG; goat β-lactoglobulin; rmsd; root mean square deviation; Lactoglobulin; Tetracaine; Pramocaine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Thermostable chitinase II from Thermomyces lanuginosus SSBP: Cloning, structure prediction and molecular dynamics simulations

Keywords: میانگین انحراف مربع ریشه; LB; Luria Bertani; SSBP; Suren Singh Bernard Prior; cDNA; complementary deoxyribonucleic acid; RMSD; root mean square deviation; SignalP; signal peptide; MD; molecular dynamics; GROMACS; GROningen MAchine for Chemical Simulations; OPLS-AA/L; optimized pot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular dynamics simulation study reveals potential substrate entry path into γ-secretase/presenilin-1

Keywords: میانگین انحراف مربع ریشه; PS1; presenilin 1; APP; amyloid precursor protein; AD; Alzheimer's disease; NTF; N-terminal Fragment; CTF; C-terminal Fragment; TM; transmembrane domain; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPE; 1-palmitoyl-2-oleoyl-sn-glycero-3-pho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies

Keywords: میانگین انحراف مربع ریشه; AA; arachidonic acid; a.m.u.; atomic mass unit; a.u.; arbitrary units; CYP; cytochrome P450; Deb; debrisoquine; 1- 3-, 4-, 5-, 6-, 7- and 8-OH-Deb; 1-, 3-, 4-, 5-, 6-, 7-, and 8-hydroxy-debrisoquine, respectively; N-OH-Deb; N-hydroxy-debrisoquine; Deb-ure

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Structural and functional analysis of two universal stress proteins YdaA and YnaF from Salmonella typhimurium: possible roles in microbial stress tolerance

Keywords: میانگین انحراف مربع ریشه; USP; Universal Stress Protein; ATP; adenosine triphosphate; RMSD; root mean square deviation; Universal stress proteins; ATPase; Chloride ion binding; Zinc binding; Fatty acid metabolism;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures

Keywords: میانگین انحراف مربع ریشه; ACSF; artificial cerebrospinal fluid; AMPA; 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid; BDNF; brain-derived neurotrophic factor; CA1; cornu ammonis area 1; CTZ; cyclothiazide; DEPC; diethylpyrocarbonate; DMSO; dimethyl sulfoxide; fEPSP; fie

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Flupyradifurone (Sivanto™) and its novel butenolide pharmacophore: Structural considerations

Keywords: میانگین انحراف مربع ریشه; ACh; acetylcholine; BgTx; bungarotoxin; CNS; central nervous system; DFT; density functional theory; FPF; flupyradifurone; IMD; imidacloprid; IRM; insect resistance management; IRAC; Insecticide Resistance Action Committee; nAChR; nicotinic acetylcholine

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Homology modeling, functional annotation and comparative genomics of outer membrane protein H of Pasteurella multocida

Keywords: میانگین انحراف مربع ریشه; 3D; Three dimensional; BLAST; Basic Local Alignment Search Tool; BLASTp; Protein-BLAST; CDD; Conserved Domains Database; Da; Dalton; DEG; Database of Essential Genes; GO; Gene Ontology; GRAVY; Grand Average of Hydropathy; KAAS; KEGG automatic annotation s

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Structure and antimicrobial activity of platypus 'intermediate' defensin-like peptide

Keywords: میانگین انحراف مربع ریشه; DLP; defensin like-peptide; Int-DLP; intermediate defensin-like peptide; Int-DLPa; intermediate defensin-like peptide analogue; OvCNP; Ornithorhyncus venom C-type natriuretic peptide; DQF-COSY; double-quantum filtered correlation spectroscopy; NOESY; nucl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The crystal structure of the amidohydrolase VinJ shows a unique hydrophobic tunnel for its interaction with polyketide substrates

Keywords: میانگین انحراف مربع ریشه; ACP; acyl carrier protein; pNA; p-nitroanilide; r.m.s.d.; root mean square deviation; F1; tricon-interacting peptidase F1; PIP; proline iminopeptidase; PAP; prolyl aminopeptidase; Crystal structure; Amidohydrolase; Biosynthesis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Keywords: میانگین انحراف مربع ریشه; BmMTAN; Brucella melitensis MTAN; INT; 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride; MTA; 5′-methylthioadenosine; MTAN; MTA/SAH nucleosidase; NP-1; nucleoside phosphorylase-1; PDB; Protein Data Bank; PEG; polyethylene glycol; r.m.s.d.

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The crystal structure of arginyl-tRNA synthetase from Homo sapiens

Keywords: میانگین انحراف مربع ریشه; aaRS; aminoacyl-tRNA synthetase; hArgRS; free isoform of human ArgRS; PBD; Protein Data Bank; Nd; N-terminal domain; Ins1; insertion domain 1; Ins2; insertion domain 2; Cd; C-terminal domain; RMSD; root mean square deviation; Arginyl-tRNA synthetase; l-Ca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Structural and mutagenetic analyses of a 1,3-1,4-β-glucanase from Paecilomyces thermophila

Keywords: میانگین انحراف مربع ریشه; CBI; cellobiose; CTT; cellotetraose; DEAE; diethylaminoethyl; GLC; glucose; GTI; 1,3-1,4-β-glucotriose; MR; molecular replacement; PEG; polyethyleneglycol; RMSD; root mean square deviation; Tris; tris (hydroxymethyl) aminomethane; 1,3-1,4-β-Glucanas

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention

Keywords: میانگین انحراف مربع ریشه; RXR; retinoid X receptor; RAR; retinoic acid receptor; RA; retinoic acid; LBD; ligand binding domain; IBX; 2-iodoxybenzoic acid; RKE; rat kidney epithelial; SCC; squamous cell carcinoma; TG; triglycerides; LBP; ligand binding pocket; THF; tetrahydrofuran;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics

Keywords: میانگین انحراف مربع ریشه; HNL; hydroxynitrile lyase; S-HNL; S-selective hydroxynitrile lyase; (R)-Man; (R)-mandelonitrile; (S)-Man; (S)-mandelonitrile; rac-Man; racemic mandelonitrile; MD; molecular dynamics; RMSD; root mean square deviation; RMSF; root mean square fluctuation; Me

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications

Keywords: میانگین انحراف مربع ریشه; wHTH; winged helix-turn-helix; CT; cholera toxin; IPTG; Isopropyl β-d-1-thiogalactopyranoside; Ni-NTA; nickel-nitrilotriacetic acid; PEG; polyethylene glycol; TCEP; (tris(2-carboxyethyl)phosphine); RMSD; root mean square deviation; SDM; structural di

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Ensemble docking and molecular dynamics identify knoevenagel curcumin derivatives with potent anti-EGFR activity

Keywords: میانگین انحراف مربع ریشه; EGFR; epidermal growth factor receptor; TK; tyrosine kinases; NSCLC; non-small-cell lung carcinoma; NCEs; new chemical entities; MD; molecular dynamics; RMSD; root mean square deviation; EGFR; Tyrosine kinase; Curcumin; Ensemble docking; Molecular dynamic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties

Keywords: میانگین انحراف مربع ریشه; CA; carbonic anhydrase; hCA; human carbonic anhydrase; CAI; carbonic anhydrase inhibitor; SAR; structure-activity relationship; Zn; zinc; AZM; acetazolamide; MZA; methazolamide; EZA; ethoxzolamide; DCP; dibromophenamide; DZA; dorzolamide; BRZ; brinzolam

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4

Keywords: میانگین انحراف مربع ریشه; ECT2; the epithelial cell transforming protein 2; DH-PH; Dbl homology domain and Pleckstrin homology domain; Plk1; Polo-like kinase 1; MKLP1; mitotic kinesin-like protein 1; ITC; isothermal titration calorimetry; TEV; tobacco etch virus; IPTG; isopropyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Structure-function studies on jaburetox, a recombinant insecticidal peptide derived from jack bean (Canavalia ensiformis) urease

Keywords: میانگین انحراف مربع ریشه; Jbtx; jaburetox; JbtxΔ-β; β-hairpin deleted version of Jbtx; Jbtx N-ter; N-terminal domain of Jbtx; Jbtx C-ter; C-terminal domain of Jbtx; Jbtx-2Ec; a version of Jbtx containing a V5 epitope; LUV; large unilamellar vesicle; MD; molecular dynamics; RMSD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

G-quadruplex DNA recognition by nucleophosmin: New insights from protein dissection

Keywords: میانگین انحراف مربع ریشه; TIS; Triisopropylsilane; TFA; Trifluoroacetic acid; DMF; Dimethylformamide; DCM; Dichloromethane; HBTU; 1-H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-hexafluorophosphate(1-), 3 oxide; HOBt; N-hydroxybenzotriazole; DIEA; Di-isopropylethylamine; Fmoc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular modeling and molecular dynamics simulations of GPI 14 in Leishmania major: Insight into the catalytic site for active site directed drug design

Keywords: میانگین انحراف مربع ریشه; CL; cutaneous leishmaniasis; MCL; mucocutaneous leishmaniasis; VL; visceral leishmaniasis; LPG; lipophosphoglycan; GIPLs; glycoinositolphospholipids; GPI; glycosylphosphatidylinositol; iNOS; inducible nitric oxide synthase; NO; nitric oxide; PPG; proteoph

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Love-Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interaction

Keywords: میانگین انحراف مربع ریشه; D, Dead; non-binding streptavidin mutant; EC50; half-maximal effective concentration; L3/4; loop connecting β-strands 3 and 4; LH; Love-Hate ligand; rmsd; root mean square deviation; SA; wild-type core streptavidin; SAe; core streptavidin with C-termin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

Keywords: میانگین انحراف مربع ریشه; SARS-CoV; Severe Acute Respiratory Syndrome coronavirus; 3CLpro; 3 Chymotrypsin-like cysteine protease; MD; molecular dynamics; VS; virtual screening; CSM; computational solvent mapping; ROC; receiver operating characteristic; RMSD; root mean square devia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The C-terminal extension of bacterial flavodoxin-reductases: Involvement in the hydride transfer mechanism from the coenzyme

Keywords: میانگین انحراف مربع ریشه; FAD and FADH−; oxidised and two-electron reduced forms of the flavin adenine dinucleotide; WT; wild-type; CTC; charge transfer complex; HT; hydride transfer; ITC; isothermal titration calorimetry; FNR/FPR; plastidic/bacterial ferredoxin-NADP+ reductase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

X-ray vs. NMR structure of N-terminal domain of δ-subunit of RNA polymerase

Keywords: میانگین انحراف مربع ریشه; RNAP; RNA polymerase; Nδ; N-terminal domain of the δ subunit of RNAP; SAD; single wavelength anomalous dispersion; RMSD; root mean square deviation; Ni-NTA column; nickel-nitrilotriacetic acid column; RDC; residual dipolar coupling; NOE; nuclear Overhau

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity

Keywords: میانگین انحراف مربع ریشه; p53; Ubiquitylation; Oligomerization; Transcription; Proteasome; OD; Oligomerization Domain; Bax; Bcl2-associated X protein; Bcl-XL; B-cell lymphoma-extralarge; PUMA; p5pregulated Modulator of Apoptosis; Noxa; Noxious stress induced protein; Bid; BH3 inte

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

A DFT study of the applicability of the charge balance model in two-metal enzymes: The case of cAMP-dependent protein kinase

Keywords: میانگین انحراف مربع ریشه; TSA; transition state analogues; PKA; protein kinase A; RMSD; root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: Implications for epigenetic regulation

Keywords: میانگین انحراف مربع ریشه; CD; circular dichroism; FRET; fluorescence resonance energy transfer; PCR; reverse transcription-polymerase chain reaction; RMSD; root mean square deviation; FAM; 6-carboxyfluorescein; TAMRA; tetramethylrhodamine; Cytosine; DNA methylation; Bcl-2; G-quadr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Conserved hydrogen bonds and water molecules in MDR HIV-1 protease substrate complexes

Keywords: میانگین انحراف مربع ریشه; MDR; multi-drug resistant; HIV; human immunodeficiency virus; WT; wild type; HAART; highly active antiretroviral therapy; PR; protease; MA; matrix; CA; capsid; NC; nucleocapsid; RT; reverse transcriptase; IN; integrase; RH; rNase H; RMSD; root mean square

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: Virtual screening and activity assays

Keywords: میانگین انحراف مربع ریشه; HIV-1 Integrase; LEDGF/p75; Protein-protein interaction inhibitors; LEDGINs; Natural products; Virtual screening; AIDS; acquired immunodeficiency syndrome; CCD; catalytic core domain; HIV-1; human immunodeficiency virus type 1; IBD; integrase binding do

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

NMR structure of 2′-O-(2-methoxyethyl) modified and C5-methylated RNA dodecamer duplex

Keywords: میانگین انحراف مربع ریشه; MOE; Methylation; RNA interference; NMR; 2′-MOE; 2′-O-(2-methoxyethly); NMR; nuclear magnetic resonance; NOESY; nuclear Overhauser effect spectroscopy; DQF-COSY; double-quantum filtered correlation spectroscopy; Tm; melting temperature; r.m.s.d.; root

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The variability of the large genomic segment of Ťahyňa orthobunyavirus and an all-atom exploration of its anti-viral drug resistance

Keywords: میانگین انحراف مربع ریشه; AKAV; Akabane virus; BUNV; Bunyamwera virus; CAL; California complex; CHATV; Chatanga virus; DPBA; 2,4-dioxo-4-phenylbutanoic acid; dS; synonymous nucleotide substitution rate; dN; non-synonymous nucleotide substitution rate; ED; endonuclease domain; INKV

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

(−)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites

Keywords: میانگین انحراف مربع ریشه; AChR; nicotinic acetylcholine receptor; NSRI; norepinephrine selective reuptake inhibitor; TCAs; tricyclic antidepressants; NCA; non-competitive antagonist; (−)-reboxetine; (−)-R,R-([2-[α[2-ethoxyphenoxy]benzyl]-morpholine); PCP; phencyclidine; [3H]T

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

NMR and molecular modelling studies on elastase inhibitor-peptides for wound management

Keywords: میانگین انحراف مربع ریشه; MMPs; matrix metalloproteinases; PPE; porcine pancreatic elastase; SLPI; secretory leukocyte protease inhibitor; Pep4; KRCCPDTCGIKCL; Pep4(P); Pep4 phosphorylated; Pep4M; KRMMPDTMGIKML; Pep4M(P); Pep4M phosphorylated; PepBBI (Bowman-Birk inhibitor); WCTAS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety

Keywords: میانگین انحراف مربع ریشه; CA; carbonic anhydrase; hCA; human carbonic anhydrase; CAI; carbonic anhydrase inhibitor; SAR; structure-activity relationship; Zn; zinc; AZM; acetazolamide; MZA; methazolamide; EZA; ethoxzolamide; DCP; dibromophenamide; DZA; dorzolamide; BRZ; brinzolam

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors

Keywords: میانگین انحراف مربع ریشه; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; AD; Alzheimer's disease; AChEI; acetylcholinesterase inhibitors; Aβ; β-amyloid; PAS; peripheral anionic site; eeAChE; Electrophorus electricus AChE; TcAChE; Torpedo californica AChE; hAChE; hum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms

Keywords: میانگین انحراف مربع ریشه; nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; CCh; carbamylcholine; [3H]MLA; [3H]methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activation); Ki; inhibition constan

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands

Keywords: میانگین انحراف مربع ریشه; Purinergic receptors; Adenosine receptors; Adenosine receptor antagonists; Adenine derivatives; Purine derivatives; Molecular modelling; AR; adenosine receptor; GPCR; G protein-coupled receptor; CNS; central nervous system; DMF; dimethylformamide; NBS; N-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking

Keywords: میانگین انحراف مربع ریشه; AR; apelin receptor; AR55; residues 1-55 of AR; BSA; bovine serum albumin; CSI; chemical shift index; DMEM; Dulbecco's modified eagle medium; DPC; dodecylphosphocholine; DPPC; dipalmitoylphosphatidylcholine; DSS; sodium 2,2-dimethyl-2-silapentane-5-sulf

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

The compact conformation of the Plasmodium knowlesi myosin tail interacting protein MTIP in complex with the C-terminal helix of myosin A

Keywords: میانگین انحراف مربع ریشه; D2; domain 2 of MTIP; D3; domain 3 of MTIP; GAP; glideosome-associated protein; MTIP; myosin-tail interacting protein; PknoMTIP; Plasmodium knowlesi MTIP; PfalMTIP; Plasmodium falciparum MTIP; rmsd; root mean square deviation; TRAP; thrombospondin-related

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody

Keywords: میانگین انحراف مربع ریشه; CDR; complementarity defining region; D1; N-terminal domain 1 of MTIP; D2; domain 2 of MTIP; D3; domain 3 of MTIP; GAP; glideosome-associated protein; MTIP; myosin-tail interacting protein; PknoMTIP; Plasmodium knowlesi MTIP; PfalMTIP; Plasmodium falcipar

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه