دانلود مقالات ISI درباره Rxrα + ترجمه فارسی

مدولاسیون بازسازی همزمان با سولفورفان باعث کاهش دیابت و سندرم قلبی می شود

Concerted redox modulation by sulforaphane alleviates diabetes and cardiometabolic syndrome

Keywords: ACS; Acyl-CoA synthetase; ARE/EpRE; Antioxidant/electrophile response element; Bcl-2; B-cell lymphoma 2; BMI; Body mass index; BSP; Broccoli sprout powder; CAT; Catalase; C/EBP; CCAAT/enhancer-binding protein; CD36; CD36 molecule/thrombospondin receptor;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

قطبش ماکروفاژ و التهاب متعادلی

Macrophage polarization and meta-inflammation

Keywords: AGO; Argonaute; ARG1; arginase1; ATM; adipose tissue macrophage; BAT; brown adipose tissue; BMDM; bone marrow derived macrophage; C/EBP; CCAAT-enhancer-binding proteins; CCL2; C-C Motif Chemokine Ligand 2; CCR2; C-C Motif Chemokine Receptor 2; CLS; crown-

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

بازسازی کروماتین بیان بیانات کاتالاز را در طی انطباق سلول های سرطانی با استرس اکسیداتیو مزمن تنظیم می کند

Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress

Keywords: AP-1; activator protein 1; APEX1; , DNA-(apurinic or apyrimidinic site) lyase; AP-MS; , affinity purification followed by mass spectrometry; ARID3A; , AT-rich interactive domain-containing protein 3A; Asc/Men; , ascorbate/menadione; ATRA; , all-trans-Reti

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

مکانیزم های آلوستریک گیرنده های هسته ای: بینش از شبیه سازی های محاسباتی

Allosteric mechanisms of nuclear receptors: insights from computational simulations

Keywords: AF-2; activation function 2; AP; alternative pocket; AR; androgen receptor; BF-3; binding function 3; DBD; DNA-binding domain; ER; estrogen receptor; GP; genomic pocket; GR; glucocorticoid receptor; H12; helix 12; HDX; hydrogen/deuterium exchange; LBD; li

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2014 سفارش ترجمه

انسداد گیرنده پروژسترون به طور موثر زنده ماندن سلول بتای جزیره پانکراس را محافظت می کند

Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability

Keywords: PR; progesterone receptor; PIC; pro-inflammatory cytokines; P4; progesterone; Erk; extracellular-signal-regulated kinase 1/2; p53; protein 53; AKT; protein kinase B; TRAF2; tumor necrosis factor receptor-associated factor 2; PR-KO; PR knockout; Mif; mifep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

گیرنده های هورمون تیروئید و سرطان

Thyroid hormone receptors and cancer

Keywords: BM; basement membrane; ECM; extracellular membrane; EMT; epithelial mesenchymal transition; FAK; focal adhesion kinase; MAPK; mitogen-activated protein kinase; LOH; loss of heterozygosity; NCOR1; nuclear receptor co-repressor 1; MMP; matrix metalloprotein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Expression and clinical significance of retinoid X receptor α in esophageal carcinoma

Keywords: RXRα; Esophageal carcinoma; Biomarker; Expression; Prognosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

The Involvement of PPARs in the Selective Regulation of Brain CYP2D by Growth Hormone

Keywords: CYP2D; cytochrome P450 2D; DCN; deep cerebellar nuclei; GH; growth hormone; GHR; growth hormone receptor; PPARα; peroxisome proliferator activated receptors alpha; PPARβ; peroxisome proliferator activated receptors beta; PPARγ; peroxisome proliferator

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ

Keywords: Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice

Keywords: 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Development of a highly sensitive in vitro system to detect and discriminate between vitamin D receptor agonists and antagonists based on split-luciferase technique

Keywords: CYP27B1; 25-hydroxyvitamin D3 1α-hydroxylase; VDR; vitamin D receptor; LBD; ligand binding domain; LucN; N-terminal domain of luciferase; LucC; C-terminal domain of luciferase; SRC-1; steroid receptor coactivating factor 1; RXRα; retinoid X receptor α;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRα from Drugbank database

Keywords: RXRα; Old drug; Agonist; Antagonist; Virtual screening; QVVCZWKLXIGYPX-ZRYTXGOBSA-N; QMRFMKFSCAFNDM-BZCZYQESSA-N; KFJUEWQQCHWYIV-QPZJVCRCSA-N; HEILJUCIFZMCAH-QTDJRPCYSA-N;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists

Keywords: FXR; farnesoid X receptor; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; SHP; small heterodimer partner; RXRα; retinoid X receptor α; 9-cis-RA; 9-cis-retinoic acid; LBD; ligand binding domain; TR-FRET; time-resolved fluorescence reso

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor

Keywords: VDR; vitamin D receptor; RXRα; retinoid X receptor α; LBD; ligand binding domain; VDRE; vitamin D responsive element; LucN; N-terminal domain of luciferase; LucC; C-terminal domain of luciferase; Vitamin D receptor; Bioluminescent sensor; Split lucifera

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Identification and expression analysis of alternatively spliced new transcript isoform of Bax gene in mouse

Keywords: Bcl-2; B-cell lymphoma 2; BH; Bcl-2 homology; TM; transmembrane; MOM; mitochondrial outer membrane; ART; Apoptosis Regulating Target; qRT-PCR; quantitative real time PCR; DOPE; Discrete Optimized Protein Energy; GR; glucocorticoid receptor; Sp1; specifici

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Nrf2 signaling pathway: Pivotal roles in inflammation

Keywords: ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

The commonly used nonionic surfactant Span 80 has RXRα transactivation activity, which likely increases the obesogenic potential of oil dispersants and food emulsifiers

Keywords: DWH; Deepwater Horizon; CWAF; Corexit-enhanced Water Accommodated Fraction; DOSS; dioctyl sodium sulfosuccinate; EDCs; endocrine disrupting chemicals; RXRα; retinoid X receptor alpha; PPARγ; peroxisome proliferator-activated receptor gamma; TBT; tributy

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Cell-based and in silico evidence against quercetin and structurally-related flavonols as activators of vitamin D receptor

Keywords: CAS; chemical abstracts service; CYP24A1; cytochrome P450 24A1; DMSO; dimethyl sulfoxide; hRXRα; human retinoid X receptor alpha; hSRC-1; human steroid receptor coactivator-1; hVDR; human vitamin D receptor; mVDR; mouse vitamin D receptor; LBD; ligand-bi

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα

Keywords: PPARγ; Flightless-I (FLII); RXRα; Adipogenesis; Coregulators; Interaction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The epicardium as modulator of the cardiac autonomic response during early development

Keywords: β1AR; β1 adrenergic receptor; β2AR; β2 adrenergic receptor; cANS; cardiac autonomic nervous system; CTNI; cardiac Troponin I; E; embryonic day; EMT; epithelial-to-mesenchymal transition; HH; Hamburger and Hamilton; NCAM; Neural Cell Adhesion Molecule;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease

Keywords: 3-Hydroxyflavone (PubChem CID: 11349); Galangin (PubChem CID: 5281616); Datiscetin (PubChem CID: 5281610); Kaempferol (PubChem CID: 5280863); Morin (PubChem CID: 5281670); Quercetin dihydrate (PubChem CID: 5284452); Isorhamnetin (PubChem CID: 5281654); Ta

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of farnesoid X receptor induces RECK expression in mouse liver

Keywords: FXR; farnesoid X receptor; RXRα; retinoid X receptor α; SHP; small heterodimer partner; SREBP-1c; sterol regulatory element-binding protein-1c; PEPCK; phosphoenolpyruvate carboxykinase; RECK; reversion-inducing cysteine rich protein with Kazal motifs; M

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

Keywords: FXR; farnesoid X receptor; ALD; alcoholic liver disease; SHP; small heterodimer partner; BSEP; bile salt export pump; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; CYP2E1; c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of RAS/ERK alone is insufficient to inhibit RXRα function and deplete retinoic acid in hepatocytes

Keywords: H-ras12V; Hepatic tumor; RXRα; Retinoic acid;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleImpaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain

Keywords: RXRα; Retinoid X Receptor α; NR; Nuclear Receptors; DBD; DNA-Binding Domain; CA; cholic acid; BA; bile acids; Bile acids; Liver injury; Nuclear receptors; Retinoid x receptor; Apoptosis; DDC; Biliary fibrosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol

Keywords: Liver; Bile Acid; Farnesoid X Receptor; Transcriptional Regulation; Asbt; rodent apical sodium dependent bile acid transporter; CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation; Cyp7a1/CYP7A1; rodent/human cholesterol 7α-hydroxylase; 1,25

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Short CommunicationInsulin-like factor binding protein-3 promotes the G1 cell cycle arrest in several cancer cell lines

Keywords: IGFBP-3; insulin-like growth factor binding protein-3; IGF; insulin-like growth factor; IGFBPs; insulin-like growth factor binding proteins; TNF-α; tumor necrosis factor-α; RXRα; retinoid X rexeptorα; CDK; cyclin-dependent kinase; FCS; fetal calf seru

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic Variations of NR1I3 and NR2B1 in Asian Populations

Keywords: NR1I3; NR2B1; CAR; RXRα; pharmacogenetics; Asians; polymorphisms; tag-SNPs; in-silieo prediction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes

Keywords: LXRα/β; Liver X receptor α/β; miRs; MicroRNAs; SREBP-1c; sterol-regulatory element binding protein 1c; FAS; fatty acid synthase; ChREBP; carbohydrate responsive element-binding protein; ACC1; acetyl-CoA carboxylase 1; RXRα; retinoid X receptor α; LX

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The potential of microRNAs in liver fibrosis

Keywords: miRNA; microRNA; ECM; extracellular matrix; HSC; hepatic stellate cell; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; 3'UTR; 3'untranslated region; PDGF; platelet-derived growth factor; HCC; hepatocellular carcinoma; ACSL1; acyl-C

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Crosstalk between the peroxisome proliferator-activated receptor γ (PPARγ) and the vitamin D receptor (VDR) in human breast cancer cells: PPARγ binds to VDR and inhibits 1α,25-dihydroxyvitamin D3 mediated transactivation

Keywords: VDR; 1α,25(OH)2D3; PPARγ; RXRα; Crosstalk; Transrepression;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol inhibits genistein-induced multi-drug resistance protein 2 (MRP2) expression in HepG2 cells

Keywords: MRP2; Genistein; Resveratrol; Cancer chemopreventive phytochemical; RXRα;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Sensitive bioassay for detection of PPARα potentially hazardous ligands with gold nanoparticle probe

Keywords: GNP; gold nanoparticle; LC-MS; liquid chromatography/tandem mass spectrometry; PFOA; perfluorooctanoic acid; PFOS; perfluorooctane sulfonate; MEHP; mono-(2-ethylhexyl) phthalate; PPARα; peroxisome proliferator-activated receptor α; PPRE; PPARα-respon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Biological effects of marine contaminated sediments on Sparus aurata juveniles

Keywords: Sparus aurata; TRα; ERα; RXRα; GR; MTT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of RXRα gene silencing on the porcine adipocyte differentiation in vitro

Keywords: Porcine; Small interfering RNA; Retinoid X receptor α; RXRα; PPARγ; C/EBPα; Preadipocytes; Adipocyte differentiation; In vitro;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of porcine preadipocyte in vitro

Keywords: 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; Glut4; glucose transporter 4; GPDH; glycerol-3-phosphate dehydrogenase; LPL; lipoprotein lipase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PEPCK; phosphoenolpyruvate carboxykinase; PPARγ; pe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Convergent proliferative response and divergent morphogenic pathways induced by epicardial and endocardial signaling in fetal heart development

Keywords: Heart development; Epicardium; Compact zone; Ventricular chamber; Retinoic acid; RXRα;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway

Keywords: Proteasome inhibitor; PPARγ; RXRα; PKC; PPRE; Degradation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR)

Keywords: AR; androgen receptor; β-Gal; β-galactosidase; CYP3A; cytochrome P4503A; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DR3; direct repeat with 3 nucleotide spacer; EC50; effective concentration for half-maximal response; ER; estrogen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular chemoprevention by selenium: A genomic approach

Keywords: APO-E; apolipoprotein-E; AOM; azoxymethane; AR; androgen receptor; CYP450; cytochrome p450; DHFR; dihydrofolate reductase; DMBA; 7,12-dimethylbenz[a]anthracene; EGR1; early growth response gene 1; ER; estrogen receptor; FABP; fatty acid binding protein; G

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه