Keywords: S-adenosyl-L-metionine; Histone methylation; Histone demethylation; Lung cancer; Histone methyltransferase; Histone demethylase; Inhibitors; ALK; anaplastic lymphoma kinase; DUSP3; dual-specificity phosphatase 3; Elk1; ETS-domain containing protein; EMT; epithelial-to-mesenchyma
مقالات ISI S-adenosyl-L-metionine (ترجمه نشده)
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Keywords: S-adenosyl-L-metionine; Arsenic; Inorganic arsenic; Carcinogenesis; Epidemiology; Methylation; Signal transduction; As3MT; arsenic-3-methyl transferase enzyme; BER; base excision repair; CA; chromosomal aberration; DAPK; death-associated protein kinase; DMA; dimethylarsinous aci
Keywords: S-adenosyl-L-metionine; ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a
Keywords: S-adenosyl-L-metionine; Jasminum sambac; Phenylalanine ammonia-lyase; Acetyl-coenzyme A: benzylalcohol acetyltransferase; Benzylacetate; S-Adenosyl-l-methionine; Benzoic acid carboxyl methyl transferase; Methylbenzoate; S-Adenosyl-l-methionine; Salicylic acid carboxyl methyltran
Keywords: S-adenosyl-L-metionine; ETC; electron transport complexes; ROS/RNS; reactive oxygen or nitrogen spices; âÏm; mitochondrial inner membrane potential; TCA; TriCarboxylic acid cycle; MPTP; mitochondrial permeability transition pore; mtDNA; mitochondrial DNA; ND5; NADH dehydrogen
Keywords: S-adenosyl-L-metionine; Ala; alanine; Arg; arginine; Asn; asparagine; Asp; aspartic acid; Cys; cysteine; Gln; glutamine; Glu; glutamic acid; Gly; glycine; His; histidine; Ile; isoleucine; Leu; leucine; Lys; lysine; Met; methionine; Phe; phenylalanine; Pro; proline; Ser; serine;
Keywords: S-adenosyl-L-metionine; AdoMet; S-adenosyl-l-methionine; AMI-1; arginine N-methyltransferase inhibitor-1; AMI-5; arginine(lysine) N-methyltransferase inhibitor-5; DAPI; 4â²,6-diamidino-2-phenylindole; DNMTs; DNA methyltransferases; FDA; Food and Drug Administration; HDACs; hist
Keywords: S-adenosyl-L-metionine; PRMT; protein arginine methyltransferase; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; SFG; sinefungin; PDB; Protein Data Bank; rmsd; root square mean deviation; ESI-MS; electrospray ionization mass spectrometry; LC-MS/MS; liquid chroma
Keywords: S-adenosyl-L-metionine; NAFLD; Non-alcoholic fatty liver disease; dG-TAM; (E)-α-(deoxyguanosin-N2-yl)-tamoxifen; dG-DesMeTAM; (E)-α-(deoxyguanosin-N2-yl)-N-desmethyltamoxifen; ALT; alanine transaminase; AST; aspartate transaminase; LDH; lactate dehydrogenase; α-SMA; α-smooth
Keywords: S-adenosyl-L-metionine; DENV; Dengue virus; NS; non-structural protein; MTase; methyltransferase; Hel; helicase; AdoMet; S-adenosyl-l-methionine; AdoHcy; S-adenosyl-l-homocysteine; FBDD; fragment-based drug discovery; FBS; fragment-based screening; FBS-X; FBS by X-ray crystallog
Keywords: S-adenosyl-L-metionine; Aβ; amyloid beta; AD; Alzheimer's disease; AICD; APP intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APP; amyloid β precursor protein; Apo E; apolipoprotein E; BACE1; β-site APP converting enzyme 1; BDNF; brain derive
Keywords: S-adenosyl-L-metionine; BChl; bacteriochlorophyll; BPhe; bacteriopheophytin; Cba.; Chlorobaculum; DLS; dynamic light scattering; ELSD; evaporative light scattering detector; ESI; electrospray ionization; MGDG; monogalactosyldiacylglyceride; PAGE; polyacrylamide gel electrophores
Keywords: S-adenosyl-L-metionine; Cyclopropane fatty acid synthase; Mycolic acid methyltransferase; Fatty acid methyl ester; Enzyme mechanism; AdoHcy; S-adenosyl-l-homocysteine; AdoMet; S-adenosyl-l-methionine; CS; cyclopropane synthase; CFAS; cyclopropane fatty acid synthase; CMAS; cyclo
HSP70 Copurifies with Zika Virus Particles
Keywords: S-adenosyl-L-metionine; AHI; allosteric HSP70 inhibitor; DAA; direct acting antiviral; DGC; density-gradient centrifugation; HCV; hepatitis C virus; HSP; heat shock protein; MOI; multiplicity of infection; MTase; methyltransferase; NBD; nucleotide binding domain; NCR; non-coding
Dimethylsulfoniopropionate biosynthesis in a diatom Thalassiosira pseudonana: Identification of a gene encoding MTHB-methyltransferase
Keywords: S-adenosyl-L-metionine; Algae; Diatom; Dimethylsulfoniopropionate; Compatible solute; MTHB methyltransferase; Thalassiosira pseudonana; ASW; artificial sea water; DMSHB; 4-dimethylsulfonio-2-hydroxy-butyrate; DMSP; dimethylsulfoniopropionate; GB; glycine betaine; IPTG; isopropyl
Biosynthetic pathways of glycinebetaine in Thalassiosira pseudonana; functional characterization of enzyme catalyzing three-step methylation of glycine
Keywords: S-adenosyl-L-metionine; Betaine; Betaine synthetic pathway; Choline dehydrogenase; GSDMT; Thalassiosira pseudonana; AdoMet; S-adenosyl-L-methionine; ASW; artificial sea water; CDH; choline dehydrogenase; CMO; choline monooxygenase; DMSP; dimethyl surfoniopropionate; MT; methyltr
Differential metabolism of L-phenylalanine in the formation of aromatic volatiles in melon (Cucumis melo L.) fruit
Keywords: S-adenosyl-L-metionine; Cucumis melo L.; Cucurbitaceae; Melon; L-phenylalanine metabolism; Phenylpropanoid aroma volatiles; (E)-cinnamic acid:coenzyme A ligase; Benzoic acid:S-adenosyl-L-methionine carboxyl methyltransferase; (E)-cinnamaldehyde; Methyl benzoate; AAT; alcohol acy
Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle
Keywords: S-adenosyl-L-metionine; K; lysine; R; arginine; H3K4me1; monomethylated histone H3 lysine 4; H3K27me1; monomethylated histone H3 lysine 27; H3K9me3; trimethylated histone H3 lysine 9; HP1; heterochromatin protein 1; HKMT; histone lysine methyltransferases; SAM; S-adenosyl-L-meth
Crystal structure of cystathionine β-synthase from honeybee Apis mellifera
Keywords: S-adenosyl-L-metionine; CBS; cystathionine β-synthase; CBSDH; (CBS)-deficient homocystinuria; AdoMet; S-adenosyl-l-methionine; PLP; pyridoxal-5â²-phosphate; AmCBS; cystathionine β-synthase from Apis mellifera; dCBS; cystathionine β-synthase from Drosophila melanogaster CBS;
H2S and polysulfide metabolism: Conventional and unconventional pathways
Keywords: S-adenosyl-L-metionine; α-KB; α-ketobutyrate; α-KG; α-ketoglutarate; AdoMet; S-adenosyl-l-methionine; AOX; alternative oxidase; AOA; Aminooxyacetate; BCA; β-cyanoalanine; BKCa; large-conductance Ca2+-dependent K+ channels; BPA; bovine pulmonary arteries; CBS; cystathionine
Impact of obesity and overweight on DNA stability: Few facts and many hypotheses
Keywords: S-adenosyl-L-metionine; AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL
Germination and growth of Atriplex prostrata and Plantago coronopus: Two strategies to survive in saline habitats
Keywords: S-adenosyl-L-metionine; PAs; Polyamines; SAM; S-adenosyl-l-methionine; Put; Putrescine; Spd; Spermidine; Spm; Spermine; Proline; Putrescine; Salt stress; Seedlings; Spermidine; Spermine;
Synthesis and evaluation of analogs of 5â²-(((Z)-4-amino-2-butenyl)methylamino)-5â²-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity
Keywords: S-adenosyl-L-metionine; AdoMet; S-adenosyl-l-methionine; AdoMetDC; S-adenosylmethionine decarboxylase; BBB; bloodbrain barrier; Boc; tert-butoxycarbonyl; BSA; N,O-bis(trimethylsilyl)acetamide; CNS; central nervous system; DEAD; diethyl azodicarboxylate; DIAD; diisopropyl azodica
Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS)
Keywords: S-adenosyl-L-metionine; Cys; Cysteine; FGly; Formylglycine; GALNS; N-acetylgalactosamine-6-sulfate sulfatase; GALNSSer; GALNS cDNA containing mutation C79S; IDS; iduronate-2-sulfate sulfatase; MPS; Mucopolysaccharidoses; anSMEs; Anaerobic sulfatase maturating enzymes; SUMF1; Sul
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies
Keywords: S-adenosyl-L-metionine; DNMT; DNA methyltransferase; 5azadC; 5-aza-2â²-deoxycytidine; 5azaC; 5-azacytidine; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; DNMTi; DNMT inhibitors; HDACi; histone deacetylase inhibitors; CpGs; 5â²-CpG-3â² dinucleotides; CGis; CpG
S-Adenosyl-l-methionine production by Saccharomyces cerevisiae SAM 0801 using dl-methionine mixture: From laboratory to pilot scale
Keywords: S-adenosyl-L-metionine; S-Adenosyl-l-methionine; Fermentation; Saccharomyces cerevisiae; dl-Methionine;
Homocysteine upregulates interleukin-17A expression via NSun2-mediated RNA methylation in T lymphocytes
Keywords: S-adenosyl-L-metionine; Homocysteine (Hcy); Interleukin-17A (IL-17A); NOP2/Sun domain family; Member 2 (NSun2); Methylation; IL-17A; interleukin-17A; Hcy; homocysteine; NSun2; NOP2/Sun domain family, member 2; HHcy; hyperhomocysteinemia; CR; coding region; UTR; untranslated regi
A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus
Keywords: S-adenosyl-L-metionine; BVDV; Bovine viral diarrhea virus; C; capsid; cHP; capsid region hairpin; DENV; Dengue virus; DB; dumbbell; E; envelope; EC; elongation complex; EV71; Enterovirus 71; HCV; Hepatitis C virus; HIV-1; Human immunodeficiency virus 1; IC; initiation complex; I
Determination of thiopurine S-methyltransferase activity by hydrophilic interaction liquid chromatography hyphenated with mass spectrometry
Keywords: S-adenosyl-L-metionine; 6-MMP; 6-methylmercaptopurine; 6-MP; 6-mercaptopurine; 6-TG; 6-thioguanine; AZA; azathioprine; Cl-P; 6-chloropurine; DTT; dithiothreitol; IBD; inflammatory bowel diseases; RBC; red blood cells; SAM; S-adenosyl-l-methionine; TGN; thioguanine nucleotides; T
S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies
Keywords: S-adenosyl-L-metionine; Ado; adenosine; ADP; atomic displacement parameter; AMP; adenosine 5â²-monophosphate; Hcy; L-homocysteine; DLS; dynamic light scattering; FPLC; fast protein liquid chromatography; HEPES; (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid); iTmSAHase; in
Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design
Keywords: S-adenosyl-L-metionine; Phenyl [(phenylcarbamoyl)amino]benzene-1-sulfonate derivatives; N-Phenyl-[(phenylcarbamoyl)amino]benzene-1-sulfonamide derivatives; Fragment-linking strategy; Dengue virus; NS5 methyltransferase inhibitors; Antiviral activity; DENV; dengue virus; NS; non-
Metabolic engineering of Corynebacterium glutamicum ATCC13032 to produce S-adenosyl-l-methionine
Keywords: S-adenosyl-L-metionine; ATCC13032; S-adenosyl-l-methionine; l-Methionine; Metabolic engineering
A highly selective fluorescent probe for sensing activities of catechol-O-methyltransferase in complex biological samples
Keywords: S-adenosyl-L-metionine; COMT; catechol-O-methyltransferase; SAM; S-adenosyl-l-methionine; DHMC; 7,8-dihydroxy-4-methylcoumarin; HMMC; 7-hydroxy-8-methoxy-4-methylcoumarin; 7-MHMC; 7-methoxy-8-hydroxy-4-methylcoumarin; hLS9; human liver S9; Catechol-O-methyltransferase; Fluoresce
Elevated intracellular acetyl-CoA availability by acs2 overexpression and mls1 deletion combined with metK1 introduction enhanced SAM accumulation in Saccharomyces cerevisiae
Keywords: S-adenosyl-L-metionine; S-Adenosyl-l-methionine; Biosynthesis; Intracellular acetyl-CoA levels; Recombinant DNA; Yeast; Metabolite over production
Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase
Keywords: S-adenosyl-L-metionine; MTase; methyltransferase; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; SFG; sinefungin; r.m.s.; root mean square; TB; tuberculosis; Rv2258c; Mycobacterium tuberculosis; Small-molecule methyltransferase; Sinefungin; S-adenosyl-l-homocystei
ReviewFlavin-Dependent Methylation of RNAs: Complex Chemistry for a Simple Modification
Keywords: S-adenosyl-L-metionine; SAM; S-adenosyl-L-methionine; m5U; 5-methyluridine; tmRNA; transfer-mRNA; CH2Â =Â THF; N5,N10-methylenetetrahydrofolate; FAD; flavin adenine dinucleotide; ThyA; thymidylate synthase; dUMP; desoxyuridine monophosphate; THF; tetrahydrofolate; ThyX; thymidyl
N-methyltetrahydropyridines and pyridinium cations as toxins and comparison with naturally-occurring alkaloids
Keywords: S-adenosyl-L-metionine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP); 1-methyl-4-phenylpyridinium cation (MPP+); Paraquat; β-carboline; Tetrahydroisoquinoline; Neurotoxins; Neuroprotectants; Parkinson's disease; BBB; blood-brain barrier; βCs; β-carbolines; βC+s; β-ca
Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase
Keywords: S-adenosyl-L-metionine; H2S; hydrogen sulfide; NO; nitric oxide; CO; carbon monoxide; CcOX; cytochrome c oxidase; CBS; cystathionine β-synthase; AdoMet; S-adenosyl-l-methionine; CGL; cystathionine γ-lyase; PLP; pyridoxal 5â²-phosphate; MST; 3-mercaptopyruvate sulfurtransferas
Aromatic l-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma
Keywords: S-adenosyl-L-metionine; 3-MT; 3-methoxytyrosine; M-MTS; 3-methoxytyramine sulfate; 3-O-MD; 3-O-methyldopa; 5-HTP; 5-hydroxytryptophan; AADC; aromatic l-amino acid decarboxylase deficiency; COMT; catechol-O-methyl transferase; CSF; cerebrospinal fluid; HVA; homovanillic acid; 5-H
Enzymatic diagnosis of homocystinuria by determination of cystathionine-Ã-synthase activity in plasma using LC-MS/MS
Keywords: S-adenosyl-L-metionine; CBS; Cystathionine Ã-synthase; EDTA; Ethylenediaminetetracetic acid; DTT; Dithiothreitol; IEM; Inborn errors of metabolism; IS; Internal standard; LC-MS/MS; Liquid chromatography-tandem spectrometry; MoM; Multiples of median; PLP; Pyridoxal 5â²-phosphat
Letter to EditorFrom the RNA world to the RNA/protein world: Contribution of some riboswitch-binding species?
Keywords: S-adenosyl-L-metionine; Origin of life; l-lysine; S-adenosyl-L-methionine; Early aminoacylation; Ribonucleosyl peptides;
Co-production of S-adenosyl-L-methionine and L-isoleucine in Corynebacterium glutamicum
Keywords: S-adenosyl-L-metionine; Corynebacterium glutamicum; S-adenosyl-L-methionine; Methionine adenosyltransferase; L-methionine; L-isoleucine
Functional roles in S-adenosyl-l-methionine binding and catalysis for active site residues of the thiostrepton resistance methyltransferase
Keywords: S-adenosyl-L-metionine; Ala; alanine; Arg; arginine; Asn; asparagine; Asp; aspartic acid; ESI-MS; electrospray ionization mass spectrometry; IMAC; immobilized metal ion affinity chromatography; IPTG; isopropyl β-D-1-thiogalactopyranoside; ITC; isothermal titration calorimetry;
Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4
Keywords: S-adenosyl-L-metionine; SET domain; Ankyrin repeat; Legionella pneumophila; LegAS4; RomA; H3K4me; H3 lysine 4 monomethylation; H3K14me3; H3 lysine 14 trimethylation; SAM; S-adenosyl-l-methionine;
Expression of potato S-adenosyl-l-methionine synthase (SbSAMS) gene altered developmental characteristics and stress responses in transgenic Arabidopsis plants
Keywords: S-adenosyl-L-metionine; S-Adenosyl-l-methionine; Ethylene; Abiotic stress; SAM synthase
Proteomic analysis of protein methylation in the yeast Saccharomyces cerevisiae
Keywords: S-adenosyl-L-metionine; SAM; S-adenosyl-l-methionine; PTM; post-translational modification; HPLC-MS/MS; high performance liquid chromatography tandem mass spectrometry; FDR; false discovery rate.; Saccharomyces cerevisiae; Methylation; Proteomics; LC/MS/MS;
Are PrPCs involved in some human myelin diseases? Relating experimental studies to human pathology
Keywords: S-adenosyl-L-metionine; Abs; antibodies; Akt; cytoplasmic serine-threonine kinase from Ak mouse strain thymoma; AT; anti-TNF-α; Cbl; cobalamin; Cbl-D; Cbl-deficient; CNS; central nervous system; CoA; coenzyme A; CSF; cerebrospinal fluid; EGF; epidermal growth factor; GFAP; gl
A catalytic triad - Lys-Asn-Asp - Is essential for the catalysis of the methyl transfer in plant cation-dependent O-methyltransferases
Keywords: S-adenosyl-L-metionine; SAM; S-adenosyl-l-methionine; CCoAOMT; caffeoyl-coenzyme A dependent O-methyltransferase; OMT; O-methyltransferase; queg; quercetagetin; Ice plant; Mesembryanthemum crystallinum; Aizoaceae; Methyltransferase; Catalytic triad; Molecular modelling; Site-dir
1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells
Keywords: S-adenosyl-L-metionine; BSA; bovine serum albumin; Enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3; ESRD; end stage renal disease; FFA; free fatty acid; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxigenase-1; MCP-1; monocyte chemoattractant protein-1; 1-MNA; 1-methylnicoti
Calcineurin B-like 3 calcium sensor associates with and inhibits 5â²-methylthioadenosine nucleosidase 2 in Arabidopsis
Keywords: S-adenosyl-L-metionine; CBLs; calcineurin B-like proteins; CIPKs; CBL-interacting protein kinases; MTANs; 5â²-methylthioadenosine nucleosidases; CaMs; calmodulins; CMLs; CaM-like proteins; CDPKs; Ca2+-dependent protein kinases; YFP; yellow fluorescence protein; CFP; cyan fluore