دانلود مقالات ISI درباره Sa-Β-Gal + ترجمه فارسی

Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus

Keywords: PcG; polycomb group; EZH2; enhancer of zeste homolog 2; shRNA; short hairpin RNA; Rb; retinoblastoma; MDM2; murine double minute 2; CDKIs; cyclin-dependent kinase inhibitors; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; H3K27m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Dehydroepiandrosterone prevents linoleic acid-induced endothelial cell senescence by increasing autophagy

Keywords: ANOVA; one-way analysis of variance; AMPK; AMP-activated protein kinase; ATG; autophagy related genes; CVD; cardiovascular disease; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone sulfate; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric ox

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

Keywords: TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labelling; EdU; 5-ethynyl-2′-deoxyuridine; PI; Propidium iodide; DAPI; 4′,6-diamidino-2-phenylindole; HR; Homologous recombination; NHEJ; Non homologous end joining; SA-β-gal; Senescence asso

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Stable SREBP-1a knockdown decreases the cell proliferation rate in human preadipocyte cells without inducing senescence

Keywords: CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2B; cyclin-dependent kinase inhibitor 2B; CDKN3; cyclin-dependent kinase inhibitor 3; H3K9me3; histone H3 lysine 9 trimethylation; MTT; 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide; RRBP8;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mussel oligopeptides protect human fibroblasts from hydrogen peroxide (H2O2)-induced premature senescence

Keywords: CK; control experiment; DMSO; dimethylsulfoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; NAMPT; nicotinamide phosphoribosyltransferase; Prx1; peroxiredoxin 1; PSC; premature senescence control; SA-β-gal; senescence-associated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase

Keywords: Rb; retinoblastoma; SV40; Simian vacuolating virus 40; hTERT; human telomerase reverse transcriptase; CDK4; cyclin-dependent kinase 4; BFFs; bovine fetal fibroblasts; PEFs; pig embryonic fibroblasts; CMV; cytomegalovirus; VSV-G; vesicular stomatitis virus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways

Keywords: EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; mTOR; mammalian target of rapamycin; mTORC2; mTOR complex 2; RMAECs; rat mesenteric arterial endothelial cells; rTERT; rat telomerase reverse transcriptase; SA-β-gal; senescence-as

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Hyperosmolarity induced by high glucose promotes senescence in human glomerular mesangial cells

Keywords: SA-β-gal; senescence associated-β-galactosidase; NAC; N-acetyl-cysteine; BSA; bovine serum albumin; C12FDG; 5-dodecanoylaminofluorescein di-β-d-galactopyranoside; H2DCFDA; di chloro-di-hydrofluorescein diacetate; STZ; streptozotocin; HMC; human mesangi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

5-aza-2′-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic Myeloid Leukemia

Keywords: C12FDG; fluorogenic substrate 5-dodecanoylaminofluorescein di-β-D-galactopyranoside; CDKN; cyclin-dependent kinase inhibitor; ChIP; chromatin immunoprecipitation; CML; chronic myeloid leukemia; CTCF; CCCTC-binding factor; DAC; 5-aza-2'-deoxycytidine; D

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Senescent stroma promotes prostate cancer progression: The role of miR-210

Keywords: Senescence; Prostate cancer; Tumor microenvironment; miR-210; CAF; cancer associated fibroblast; CM; conditioned medium; COX; cyclooxygenase; EPC; endothelial progenitor cell; HIF; hypoxia-inducible factor; HPF; human prostate fibroblasts; HUVEC; human um

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells

Keywords: CRC; colorectal cancer; CPT; camptothecin; DSBs; double-strand breaks; DDR; DNA damage response; γ-H2AX; phosphorylated histone H2AX; ATM; ataxia telangiectasia mutated; Chk2; check-point kinase; AMPK; AMP-activated protein kinase; TSC2; tuberous scleros

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2014 سفارش ترجمه

Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction

Keywords: SMP30; senescence marker protein 30; IVS; intraventricular septal thickness; PW; posterior wall thickness; LVEDD; left ventricular end-diastolic dimension; LVESD; left ventricular end-systolic dimension; FS; left ventricular fractional shortening; E; peak

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Downregulation of the small GTPase Ras-related nuclear protein accelerates cellular ageing

Keywords: HDF; human diploid fibroblast; HGPS; Hutchinson-Gilford progeria syndrome; MEF; mouse embryonic fibroblast; MnSOD; manganese superoxide dismutase; Ran; Ras-related nuclear protein; ROS; reactive oxygen species; SA-β-gal; senescence-associated β-galact

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence

Keywords: OIS; oncogene-induced senescence; MEF; mouse embryonic fibroblast; ERK; extracellular signal-regulated kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphatidylinositol 3-kinase; pRb; retinoblastoma tumor suppressor protein; SA-β-Gal; sene

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts

Keywords: ROS; reactive oxygen species; PGE2; prostaglandin E2; mPGES; prostaglandin E synthase; COX-2; cyclooxygenase 2; EP; prostaglandin E receptor; NHDFs; normal human dermal fibroblasts; SA-β-Gal; senescence associated-β-galactosidase; HUVECs; human umbilica

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells

Keywords: [Ca2+]i; intracellular Ca2+ concentrations; CDK2; Cyclin-dependent kinase 2; DHP; dihydropyridine; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethylsulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetra-acetic acid; ELISA; en

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The effect of overexpression of PGC-1α on the mtDNA4834 common deletion in a rat cochlear marginal cell senescence model

Keywords: AHL; age-related hearing loss; PGC-1α; peroxisome proliferator-activated receptor-gamma coactivator 1α; MCs; marginal cells; EP; endocochlear potential; CD; common deletion; NRF-1; nuclear respiratory factor-1; Tfam; mitochondrial transcription factor A

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response

Keywords: ATM; ataxia-telangiectasia mutated; CM-H2DCFDA; 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester; DAPI; 4,6-diamidino-2-phenylindole; DNA-PKcs; the catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand bre

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation

Keywords: microRNA; miRNA; HEKn; human epidermal keratinocytes neonatal; SA-β-gal; senescence-associated beta-galactosidase; HAT; Histone Acetyl Transferase; Keratinocytes; Senescence; Proliferation; MicroRNA-191; CDK6; SATB1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis

Keywords: AdipoR; adiponectin receptor; AMPK; 5′-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence

Keywords: CKII; protein kinase CKII (also known as casein kinase II); DRB; 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole; HDAC; histone deacetylase; MBP; maltose binding protein; NOX; NADPH oxidase; PBS; phosphate-buffered saline; ROS; reactive oxygen species; SA-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation of Skp2

Keywords: ADT; androgen deprivation therapy; AIPC; androgen-independent prostate cancer; AR; androgen receptor; CS; charcoal-stripped fetal bovine serum; EMT; epithelial-to-mesenchymal transition; HP1β; heterochromatin protein 1β; IL-8; interleukin-8; IGFBP3; ins

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

Keywords: Cancer; Chemotherapy; Resistance; Polyploidy; Endoreduplication; Mitotic catastrophe; BrdU; bromodeoxyuridine; SA-β-gal; senescence-associated β-galactosidase; FBS; fetal bovine serum; PBS; phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562

Keywords: Ara-C; cytarabine, cytosine arabinoside; Bcl-XL(B-cell leukemia/lymphoma extra long); anti-apoptotic protein; CML; chronic myelogenous leukemia; DAPI; 4,6-diamidino-2-phenylidole; ΔΨm; mitochondrial transmembrane potential; DMSO; dimethyl sulfoxide; DOX

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Senescent phenotypes of skin fibroblasts from patients with Tangier disease

Keywords: ABCA1; Cdc42; SA-β-gal; Senescence; Tangier disease; Telomere;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Apoptotic cell death increases with senescence in normal human dermal fibroblast cultures

Keywords: Apoptosis; Human dermal fibroblasts; Senescence; FACScan; flow cytometry cell sorting; MMP; mitochondrial membrane potential; PI; propidium iodide; PT; permeability transition pore; ROS; reactive oxygen species; SA-β-gal; senescence-associated-β-galacto

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

The Identification of Senescence-Specific Genes during the Induction of Senescence in Prostate Cancer Cells

Keywords: Senescence; cancer; differentiation; cancer therapy; prostate; SA-β-gal; senescence-associated P-galactosidase; HPEC; human prostate epithelial cell; QPCR; quantitative reverse transcriptase polymerase chain reaction; FACS; fluorescence-activated cell so

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle

Keywords: ROS; Reactive oxygen species; DSB; Double strand break; BrdU; 5-bromo-2′-deoxyuridine; SA-β-gal; Senescence-associated β-galactosidase; PBS; Phosphate-buffered saline; Oxidative stress; DNA damage; DNA repair; S-phase; Senescence; Ageing;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation

Keywords: Actg2; actin, gamma 2, smooth muscle; bFGF; basic fibroblast growth factor; Cdk; cycline-dependent kinase; Cks1; Cdc28 protein kinase 1; Comp; cartilage oligomeric matrix protein; Ctgf; connective tissue growth factor; Dkk3; dickkopf3; Elf1a; elongation f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening

Keywords: SIPS; stress-induced premature senescence; HDF; human diploid fibroblast; PD; population doublings; SA-β-gal; senescence-associated β-galactosidase; SCGE; single cell gel electrophoresis; MV-MDD; mean value of migration distance of DNA; UDS; unscheduled

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه