Keywords: Coronaviridae; Coronavirus; NL63; Lyophilization; Stability; HCoV-NL63; CoVs; coronaviruses; HBS; HEPES Buffered Saline; HCoV; human coronavirus; IBV; Infectious Bronchitis Virus; MERS-CoV; Middle East respiratory syndrome coronavirus; PBS; phosphate buff
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Keywords: PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; DAMP; danger-associated molecular pattern; NLRP3; NOD-, LRR- and pyrin domain-containing 3; TLR; toll-like receptor; CLR; C-type lectin receptor; NLR; NOD-like receptor; RIG-I
Keywords: A(H1N1)pdm09; A(H5N1); A(H7N9); emerging; influenza; MERS-CoV; MRCP; outbreak; respiratory; SARS-CoV; virus;
Keywords: SARS-CoV; MERS-CoV; Respiratory tract infections; Clinical features; Pathogenesis; Treatment;
Keywords: AMA; amantadine; BFM; bond fluctuation method; BST-2; bone marrow stromal cell antigen 2; CD; circular dichroism; CGMD; coarse-grained molecular dynamics; ClyA; cytolysin A; DHPC; dihexanoylphosphocholine; DPC; dodecylphosphocholine; E. coli; Escherichia
Keywords: SARS-CoV; MERS-CoV; Entry inhibitors; Replicase inhibitors; Antivirals; pGlo
Keywords: MERS-CoV; SARS-CoV; Viral replication; Pathogenesis; Cytokine and chemokine response; Antigen-presentation;
The coronavirus nucleocapsid protein is ADP-ribosylated
Keywords: Coronavirus; Mouse hepatitis virus; Nucleocapsid; ADP-ribosylation; Macrodomain; PEDV; MERS-CoV; SARS-CoV;
SARS-CoV related Betacoronavirus and diverse Alphacoronavirus members found in western old-world
Keywords: Coronavirus; Bats; Europe; Emergence; SARS-CoV; MERS-CoV; Chiroptera; Evolution; Phylogenetics; Diversity;
Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3
Keywords: IFN antagonist; IRF3; SARS-CoV; ORF8; Ubiquitin-dependent degradation;
Antiviral activity of K22 against members of the order Nidovirales
Keywords: CAVV; Cavally virus; CM; convoluted membrane; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DMV; double membrane vesicles; DNA; deoxyribonucleic acid; dsRNA; double-stranded RNA; EAV; equine arteritis virus; EToV; equine toroviru
Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein
Keywords: S; Spike protein; HR; Heptad repeat; HIV-1; Human immunodeficiency virus type I; SARS-CoV; Severe acute respiratory syndrome associated coronavirus; RBD; Receptor binding domain; FP; Fusion peptide; 6-HB; Six-helix bundle; MPER; Membrane proximal external
NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion
Keywords: CoVs; Coronaviruses; SARS-CoV; Severe acute respiratory syndrome-associated coronavirus; FPs; fusion peptides; LFP; long fusion peptide; NMR; nuclear magnetic resonance; DPC; dodecyl phosphocholine; PRE; paramagnetic relaxation enhancement; SARS-CoV; Cell
Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents
Keywords: Teicoplanin; Lipoglycopeptide; Maleimide; Sulfonamide; Influenza virus inhibitor; Coronavirus; DCM; dichloromethane; DMF; dimethylformamide; CPE; cytopathic effect; Et3N; triethylamine; Galp; galactopyranose; HA; hemagglutinin; HIV; human immunodeficiency
Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference
Keywords: Influenza; RSV; Antivirals; Vaccines; Isirv-AVG; ARDS; Acute respiratory distress syndrome; AUC; Area under the curve; CAP; Community acquired pneumonia; HA; hemagglutinin; HPAI; Highly pathogenic avian influenza; LPM; Live poultry markets; MERS-CoV; Midd
Identification and evaluation of potent Middle East respiratory syndrome coronavirus (MERS-CoV) 3CLPro inhibitors
Keywords: MERS-CoV; SARS-CoV; 3C-like protease; Peptidomimetic inhibitor; Coronavirus; Picornavirus;
The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis
Keywords: Wound healing; SARS-CoV; EGFR; Fibrosis;
Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism
Keywords: IFN antagonism; NPIPB3; ORF6; phage display; SARS-CoV;
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
Keywords: SARS-CoV; MERS-CoV; Vaccine; T-cell; Epitope; Cross-reactivity;
Prophylactic and therapeutic intranasal administration with an immunomodulator, Hiltonol® (Poly IC:LC), in a lethal SARS-CoV-infected BALB/c mouse model
Keywords: BALB/c mouse; Hiltonol®; SARS-CoV; MERS-CoV;
SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling
Keywords: SARS-CoV; Papain-like protease; TGF-β1; Collagen; STAT6;
Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors
Keywords: MERS-CoV; SARS-Cov; 3CLpro; Coronavirus; Pyrazolone
Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination
Keywords: Healthcare-associated infection; Influenza virus; MERS-CoV; SARS-CoV; Surface contamination; Transmission;
Lactogenic immunity and vaccines for porcine epidemic diarrhea virus (PEDV): Historical and current concepts
Keywords: ASC; antibody secreting cells; CCL; chemokine ligand; CCR; chemokine receptor; M; membrane; MERS-CoV; Middle East respiratory syndrome coronavirus; MAdCAM-1; mucosal addressin cellular adhesion molecule 1; N; nucleocapsid; ORF; open reading frames; OLVE;
VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability
Keywords: VHL; SARS-CoV; nsp16; Replication; Ubiquitination;
The hepatitis E virus ORF1 'X-domain' residues form a putative macrodomain protein/Appr-1â³-pase catalytic-site, critical for viral RNA replication
Keywords: AA; Amino acid; Appr-1â³-pase; ADP-ribose-1â³-monophosphatase; Asn; Asparagine; CoV; Coronavirus; FACS; Fluorescence activated cell sorting; GFP; Green fluorescent protein; Gly; Glycine; HEV; Hepatitis E virus; His; Histidine; ORF; Open reading frame; P
Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
Keywords: SARS-CoV; Coronavirus; E protein; Ion channel; Viroporin; Calcium; Inflammasome; Pathogenesis;
NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV: Implications in membrane fusion
Keywords: SARS-CoV; severe acute respiratory syndrome-associated coronavirus AMPs; FP; fusion peptide; NMR; nuclear magnetic resonance; NOESY; nuclear Overhauser effect spectroscopy; TOCSY; total correlation spectroscopy; DPC; dodecyl phosphocholine; SARS-CoV; Cell
Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics
Keywords: 3D lrECM; three-dimensional cultures of laminin-rich extracellular matrix; ACs; adenylyl cyclases; AKAP; A-kinase anchoring protein; ATP; adenosine triphosphate; β-AR; β adrenergic receptor; β-arr2; β-arrestin 2; BnT; benzylthio group; cAB; cAMP-bindi
Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus
Keywords: Coronaviruses; SARS-CoV; MERS-CoV; Animal models; Receptor;
The SARS Coronavirus 3a protein binds calcium in its cytoplasmic domain
Keywords: SARS-CoV; Severe Acute Respiratory Syndrome Coronavirus; orf; open reading frame; SARS-CoV; Cyto3a protein; Calcium; Ion channel; Protein conformation;
Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins
Keywords: Antibody-dependent enhancement; Anti-spike antibody; Fc receptors; HL-CZ; SARS-CoV;
Travel implications of emerging coronaviruses: SARS and MERS-CoV
Keywords: MERS-CoV; SARS-CoV; Hajj: zoonosis; Travel
SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets
Keywords: Coronavirus; SARS-CoV; Replication; Transcription; Nonstructural proteins
Coronavirus non-structural protein 16: Evasion, attenuation, and possible treatments
Keywords: CoV; SARS-CoV; 2â²O-Methyl-transferase; 2â²O-MTase; NSP16; MDA5;
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings
Keywords: SARS-CoV; Severe Acute Respiratory Syndrome coronavirus; 3CLpro; 3 Chymotrypsin-like cysteine protease; MD; molecular dynamics; VS; virtual screening; CSM; computational solvent mapping; ROC; receiver operating characteristic; RMSD; root mean square devia
Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus
Keywords: SARS-CoV; B cells; CD4+ T cells; Antibody; Phagocytic cells; Elimination;
Accessory proteins of SARS-CoV and other coronaviruses
Keywords: SARS-CoV; Other coronaviruses; Accessory proteins; Structure and function;
Coronavirus virulence genes with main focus on SARS-CoV envelope gene
Keywords: Coronavirus; SARS-CoV; MERS-CoV; Innate immunity; Inflammation; Envelope protein;
Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread
Keywords: Coronavirus; MERS-CoV; SARS-CoV; Source; Vaccine; Therapeutics;
Quantitative and sensitive detection of the SARS-CoV spike protein using bispecific monoclonal antibody-based enzyme-linked immunoassay
Keywords: SARS-CoV; Spike protein; Bi-specific monoclonal antibodies; Quadroma; ELISA;
Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP
Keywords: SARS-CoV; severe acute respiratory syndrome coronavirus; nsp; nonstructural protein; MTase; methyltransferase; AdoMet; S-adenosyl-l-methionine; RTC; replication and transcription complex; SARS; Coronavirus; nsp14; GTP methylation; Translation;
Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava
Keywords: SARS; severe acute respiratory syndrome; CoV; coronavirus; IC50; the inhibitor concentration leading to 50% activity loss; Ki; inhibition constant; KD; dissociation constant; NMR; nuclear magnetic resonance; SPR; surface plasmon resonance; Luc; luciferase
Phages bearing affinity peptides to severe acute respiratory syndromes-associated coronavirus differentiate this virus from other viruses
Keywords: SARS-CoV; Phage display; S protein; ELISA
Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506
Keywords: EC50; 50% effective inhibitory concentration; RLU; relative light units; SARS-CoV; HCoV-NL63; HCoV-229E; FK506; Tacrolimus; Immunophilins; FKBP1A (FKBP12); FKBP1B (FKBP12.6); Inhibition of viral replication;
Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2â²-O-methyltransferase activity of nsp10/nsp16 complex
Keywords: SARS-CoV; severe acute respiratory syndrome coronavirus; nsp; nonstructural protein; RTC; replication and transcription complex; aa; amino acid; SARS; Coronavirus; nsp10; nsp16; 2â²-O-methyltransferase; Peptides;
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases
Keywords: IC50; the inhibitor concentration leading to 50% activity loss; Ki; inhibition constant; Kiapp; apparent Ki; k; rate constant; Vmax; maximum velocity; Km; Michaelis-Menten constant; kobs; apparent first-order rate constant for the transition from vi to vs
ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations
Keywords: SARS-CoV; ORF8a; Ion channel; Molecular dynamics; Bilayer recording
Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses
Keywords: Mucroporin-M1; Scorpion venom; Measles; SARS-CoV; H5N1; Antiviral;
Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication
Keywords: SARS-CoV; Frameshifting; Peptide nucleic acids; RNA replication