کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8751925 1594311 2018 19 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antiviral activity of K22 against members of the order Nidovirales
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
پیش نمایش صفحه اول مقاله
Antiviral activity of K22 against members of the order Nidovirales
چکیده انگلیسی
Possible effects of K22 on nidovirus replication were studied in suitable cell lines. K22 concentrations significantly decreasing infectious titres of the viruses included in this study ranged from 25 to 50 μM. Reduction of double-stranded RNA intermediates of viral replication in nidovirus-infected cells treated with K22 confirmed the anti-viral potential of K22. Collectively, the data show that K22 has antiviral activity against diverse lineages of nidoviruses, suggesting that the inhibitor targets a critical and conserved step during nidovirus replication.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 246, 15 February 2018, Pages 28-34
نویسندگان
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