دانلود مقالات ISI درباره Sb203580 + ترجمه فارسی

Reduced nicotinamide adenine dinucleotide phosphate inhibits rat platelet aggregation and p38 phosphorylation

Keywords: Pharmacology; NADPH; Platelet; Thrombosis; p38 MAPK; SB203580;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

SB203580 inhibits epithelial-mesenchymal transition and pulmonary fibrosis in a rat silicosis model

Keywords: p38 MAPK; p38 mitogen-activated protein kinase; EMT; epithelial-mesenchymal transition; TGF-β; transforming growth factor beta; MK-2; MAPKAPK-2; p38 MAPK; SB203580; EMT; Pulmonary fibrosis; Silica;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

BAG2 expression dictates a functional intracellular switch between the p38-dependent effects of nicotine on tau phosphorylation levels via the α7 nicotinic receptor

Keywords: CHRNA7; SH-SY5Y; Primary cell culture; Hippocampus; Methyllycaconitine; Mecamylamine; SB203580; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Oestrogen exerts anti-inflammation via p38 MAPK/NF-κB cascade in adipocytes

Keywords: LPS; lipopolysaccharides; MCP-1; monocyte chemoattractant protein-1; E2; 17β-estradiol; ERoestrogen; receptor; SB; SB203580; PDTC; pyrrolidine dithiocarbamate; PTX; pertussis toxin; WM; wortmannin; PPT; trisphenol; DPN; 2,3-bis-(4-hydroxyphenyl)-propioni

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human

Keywords: P2X7 receptor; Adenosine triphosphate; AZ11645373; KN62; SB203580;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharide

Keywords: COX-2; cyclooxygenase-2; DN; desoxo-narchinol-A; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; EtOAc; ethyl acetate; FBS; fetal bovine serum; H&E; hematoxylin and eosin; HPRT; hypoxanthine guanine phosphoribosyl-tra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatitis C virus core protein enhances HIV-1 replication in human macrophages through TLR2, JNK, and MEK1/2-dependent upregulation of TNF-α and IL-6

Keywords: APCs; antigen-presenting cells; ERK; extracellular signal-regulated protein kinase 1/2; HKLM; heat killed Listeria monocytogenes; IL-6; interleukin 6; JNK; c-Jun amino-terminal kinase; MDMs; primary monocyte derived macrophages; p38; p38 MAP kinase; PD980

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Map2k4δ - Identification and functional characterization of a novel Map2k4 splice variant

Keywords: AKT; protein kinase B; ATF-2; activating transcription factor 2; BrdU; 5-bromo-2-deoxyuridine; DVD; domain of versatile docking; E; embryonic day; ERK; extracellular signal-regulated kinase; Fas-L; Fas ligand; ID; immunodepletion; IP; immunoprecipitation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells

Keywords: ASK-1; apoptosis signal-regulating kinase 1; dexa; dexamethasone; eIF2α; eukaryotic translation initiation factor 2α; GC; glucocorticoid; GR; glucocorticoid receptor; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PP5; serine/thre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells

Keywords: DAPI; 2-(4-amidinophenyl)-6-indolecarbamidine dihydrochloride; HepG2 cells; human hepatoblastoma cancer cell line; ISO; isoorientin; MAPK; mitogen-activated protein kinases; NAC; N-acetylcystein; ROS; reactive oxygen species; SB203580; 4-(4-fluorophenyl)-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2

Keywords: P2X7R; P2X7 receptor channels; LPS; lipopolysaccharide; IL-1β; interleukin-1β; TNFα; tumor necrosis factor α; ROS; reactive oxygen species; JNK; c-Jun N-terminal kinase; ERK1/2; extracellular regulated kinases 1 and 2; MAPKs; mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Increase of oxidative stress by a novel PINK1 mutation, P209A

Keywords: AD; Alzheimer disease; ERK; extracellular signal-regulated kinase; MTT; 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolum bromide; HO-1; heme oxygenase-1; LDH; lactate dehydrogenase; LY294002; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; MEM; mini

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells

Keywords: MOR; mu opioid receptor; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein/extracellular signal-regulated kinase; NF-κB; nuclear factor-kappaB; DP; distal promoter; PP; proximal promoter; Oct-1; octame

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α

Keywords: Cerebral vasospasm; p38 Mitogen-activated protein kinase; SB203580; Subarachnoid hemorrhage; Tumor-necrosis factor-α

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Abrogation of the p38 MAPK α signaling pathway does not promote radioresistance but its activity is required for 5-Fluorouracil-associated radiosensitivity

Keywords: p38 MAPK; Radioresistance; SB203580; 5-Fluorouracil

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

Keywords: BK; large (big) conductance Ca2+-activated K+ channels; DPCPX; 1,3-dipropyl-8-cyclopentylxanthine; GUO; guanosine; GSK-3β; glycogen synthase kinase 3β; H2DCFDA; 2′,7′-dichlorofluorescein diacetate; HO-1; heme oxygenase-1; LY294002; 2-(4-morpholinyl)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway

Keywords: LPS; lipopolysaccharide; NS; normal saline; HCE1; human carboxylesterases 1; HCE2; human carboxylesterases 2; mCE1; mouse carboxylesterases 1; mCE2; mouse carboxylesterases 2; CYP450; cytochrome P450; DMEs; drug metabolism enzymes; PXR; pregnane X recepto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

The selective p38 mitogen-activated protein kinase inhibitor, SB203580, improves renal disease in MRL/lpr mouse model of systemic lupus

Keywords: MAPK; Mitogen-activated protein kinase; BUN; blood urea nitrogen; Ig; immunoglobulin; MCP; monocyte chemoattractant protein; ERK; extracellular signal-regulated kinase; JNK; c-Jun NH2-terminal protein kinase; IBD; inflammatory bowel disease; ALT; alanine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons

Keywords: K25; high potassium; K5; potassium deprivation; CGN; cerebellar granule neurons; Kmp; kaempferol; CAT; catalase; SOD; superoxide dismutase; SB; SB203580; DHEt; dihydroethidium; FDA; flourescein diacetate; PI; propidium iodide; DIV; days in vitro; MAPKs; m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning

Keywords: βKO; p38β knock-out; I/R%; myocardial infarction as a percentage of myocardium at risk of infarction; DRα; drug-resistant p38α; DRβ; drug-resistant p38β; HSP27; heat stress protein of 27 kDa; MAPK; mitogen-activated protein kinase; MAPKK; mitogen-a

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Treatment with a p38 MAPK inhibitor attenuates cisplatin nephrotoxicity starting after the beginning of renal damage

Keywords: Cisplatin; p38 mitogen activated protein kinases; SB203580; Acute renal failure; Inflammation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

p38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog

Keywords: Acrolein; Airway mucus production; MMP-9; p38 MAPK; SB203580

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes

Keywords: Human hepatocyte; p38 MAPK kinase; Extracellular-regulated kinase ERK; c-Jun-N-terminal kinase; SB203580; Cross-talk

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

SB203580, a p38 mitogen-activated protein kinase inhibitor, fails to improve functional outcome following a moderate spinal cord injury in rat

Keywords: p38 MAPK; spinal cord injury; SB203580; microglia; macrophages; neuroprotectionBBB, Basso, Beattie, Bresnahan; BSA, bovine serum albumin; EC, eriochrome cyanine; MAPK, mitogen-activated protein kinase; NO, nitric oxide; PBS, phosphate-buffered saline; SCI

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Hypoxia modulates lipopolysaccharide induced TNF-α expression in murine macrophages

Keywords: p38 MAPK; SB203580; Lipopolysaccharide; TNF-α; Hypoxia; HIF-1α; Macrophages

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of p38 MAPK induced peroxynitrite generation in LPS plus IFN-γ-stimulated rat primary astrocytes via activation of iNOS and NADPH oxidase

Keywords: Astrocyte; p38 MAPK; iNOS; NADPH oxidase; Peroxynitrite; SB203580; Dominant negative vector of p38α

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of microglia and p38 mitogen-activated protein kinase in the dorsal column nucleus contributes to tactile allodynia following peripheral nerve injury

Keywords: neuropathic pain; spinal nerve ligation; gracile nucleus; spinal cord; immunohistochemistry; behavior; ABC; avidin-biotin complex; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; ERK; extracellular signal-regulated kinase; GFAP; glial fibrillary a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

TNF-α mediates pseudorabies virus-induced apoptosis via the activation of p38 MAPK and JNK/SAPK signaling

Keywords: Pseudorabies virus; p38; JNK/SAPK; SB203580; SP600125; NF-κB; Apoptosis; TNF-α

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

SB203580 enhances interleukin-1 receptor antagonist gene expression in IFN-γ-stimulated BV2 microglial cells through a composite nuclear factor-κB/PU.1 binding site

Keywords: IL-1 receptor antagonist; Microglia; IFN-γ; SB203580; Protein kinase B; NF-κB/PU.1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn)

Keywords: Glia; Trigeminal caudalis; Central sensitization; Pain; SB203580; Fluoroacetate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA1, p42 and p38α

Keywords: LPA; lysophosphatidic acid; MAPK; mitogen-activated protein kinases; siRNA; small interfering RNA; PTX; pertussis toxin; PD; PD98059; SB; SB203580; U0; U0126; ERK; extracellular signal-regulated kinase; JNK; c-Jun/N terminal kinases; IGF; insulin-like gro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells

Keywords: caspase; cysteine-aspartate-directed proteases; cPLA2; cytosolic phospholipase A2; DD; death domain; ERK; extracellular signal-regulated kinase; hr-GFP; humanised renilla green fluorescent protein; HUVEC; human umbilical endothelial cells; ICAM; intracell

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway

Keywords: CYP2E1; Hsp90; Geldanamycin; p38 MAPK; SB203580

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Posttranscriptional regulation of TNFα expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages

Keywords: CGP57380; Mnk; mRNA translation; SB203580; U0126

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of C/EBPβ isoforms by MAPK pathways in HL60 cells induced to differentiate by 1,25-dihydroxyvitamin D3

Keywords: Vitamin D; Monocytic differentiation; C/EBP transcription factors; MEK1-ERK MAP kinase pathway; Subcellular localization; PD98059; SB203580

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells

Keywords: Hypertrophy; Leptin; p38 MAP kinase; Vascular smooth muscle cells; SB203580;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Inactivation of p38 kinase delays the onset of senescence in rabbit articuilar chondrocytes

Keywords: Chondrocyte; Senescence; p38 Kinase; SB203580;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Geniposide activates GSH S-transferase by the induction of GST M1 and GST M2 subunits involving the transcription and phosphorylation of MEK-1 signaling in rat hepatocytes

Keywords: GST; GSH S-transferase; MEK-1; extracellular-regulated kinase kinase-1; PI 3-K; phosphotidyl inositol 3-kinase; PD; PD98059; SP; SP600125; SB; SB203580; Wt; wortmannin; ARE; antioxidant-responsive element; CDNB; 1-chloro-2, 4-dinitrobenzene; GAPDH; glycer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Involvement of p38 MAP kinase-mediated cytochrome c release on sphingosine-1-phosphate (S1P)- and N-monomethyl-S1P-induced cell death of PC12 cells

Keywords: S1P; d-erythro-Sphingosine-1-phosphate; MM-S1P; d-erythro-N-Monomethyl-S1P; MAPK; mitogen-activated protein kinase; ERK1/2; extracellular regulated protein kinase 1/2; NGF; nerve growth factor; PTX; pertussis toxin; SB203580; 4-(4-fluorophenyl)-2-(4-methy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Antimycin A induced cardioprotection is dependent on pre-ischemic p38-MAPK activation but independent of MKK3

Keywords: p38-MAPK; Antimycin A; SB203580; Hsp27;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The conditional kinase ΔMEKK1:ER* selectively activates the JNK pathway and protects against serum withdrawal-induced cell death

Keywords: Bad; Bcl-2 antagonist of cell death; BH; Bcl-2 homology domain; Bim; Bcl-2 interacting modulator; BimEL; Bim extra long; ERK; Extracellular signal-regulated kinase; FBS; Fetal bovine serum; JNK; c-Jun N-terminal kinase; MAPK; Mitogen-activated protein kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Blockade of p38 map kinase inhibits complement-induced acute lung injury in a murine model

Keywords: Acute respiratory distress syndrome; ARDS; Neutrophil; Permeability; C5a; SB203580; Mouse;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Role of p38 in nitric oxide synthase and cyclooxygenase expression, and nitric oxide and PGE2 synthesis in human gingival fibroblasts stimulated with lipopolysaccharides

Keywords: Cyclooxygenase; Human gingival fibroblasts; Lipopolysaccharides; Nitric oxide synthase; p38; SB203580;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه