Keywords: AFib; atrial fibrillation; TSG; tumor suppressor gene; CM; cardiomyocytes; GWAS; genome-wide association studies; SR; sinus rhythm; SNP; small nucleotide polymorphism; ECRG4; esophageal cancer related gene-4; ZFHX3; zinc finger homeobox protein-3; Cx; con
مقالات ISI (ترجمه نشده)
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Keywords: APD; action potential duration; ARI; activation recovery interval; AS; arrhythmia score; CAVB; chronic atrioventricular block; DAD; delayed afterdepolarization; dP/dt+; left ventricular maximal contraction pressure gradient; dP/dtâ; left ventricular max
Keywords: Connexin-43; Heart; IFM; Methods; Mitochondria isolation; Mitofusin; Nagarse; SSM; Subtilisin BPN'; ADP; adenosine diphosphate; ATP5A; ATP synthase subunit alpha; BNIP3; bcl-2/adenovirus E1B 19Â kDa protein-interacting protein 3; COX4; cytochrome c oxidas
Keywords: Gene therapy; Heart failure; Adeno-associated virus; SERCA2a;
Keywords: hypertension; pulmonary; left ventricle; cardiac contractility; SERCA2a;
Keywords: AP; action potential; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CaT; Ca2+ transient; dF/dtmax; rate of contraction force rise; dF/dtmin; rate of contraction force fall; dP/dtmax; LV pressure rise; dP/dtmin; LV pressure fall; DPP-4; dipeptidyl p
Keywords: gene therapy; fibrosis; TGFbeta; myocardial infarction; AAV1; adeno-associated viral vector, serotype 1; AT1R; angiotensin II receptor 1; BZ; border zone; Ca2+; calcium ion; DAB; 3,3â²-diaminobenzidine; IZ; infarct zone; MCARD; molecular cardiac surgery
Keywords: cardiomyopathy; catecholamine; gene therapy; heart failure; AAV; adeno-associated virus; AC; adenylyl cyclase; AC6mut; AC6 mutant, contains an amino acid substitution that reduces its catalytic activity; Ad5; adenovirus-5; AKAP; A-kinase-anchoring protein
Keywords: 2D12; anti-PLB monoclonal antibody; CaMKII; Ca2Â +/calmodulin-dependent protein kinase; CPVT; catecholaminergic polymorphic ventricular tachycardia; DAD; delay afterdepolarizations; Fab; fab fragment of 2D12; KCa; Ca concentration for half-maximal effect;
Keywords: Hypoxia; Trimetazidine; Cardioprotection; RyR2; SERCA2a; NCX
Keywords: Heart; Tissue engineering; Myocardium; Biophysical properties; Force of contraction; Force frequency relationship; Calcium handling; T-tubulation; Maturation; AAV; adenovirus-associated virus; CSQ2; Calsequestrin 2; DMS; dynamic mechanical stimulation; EH
Keywords: AKAPs; A-kinase anchoring proteins; AKT; protein kinase b; Ang-II; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BH4; tetrahydrobiopterin; CaMKII; Ca/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CHF; chronic heart fa
Keywords: CaMKII; Ca2Â +/calmodulin dependent protein kinase II; cAMP; cyclic adenosine monophosphate; cTn; cardiac Troponin; DAD; delayed afterdepolarization; EAD; early afterdepolarization; ECC; excitation-contraction coupling; H2O2; hydrogen peroxide; HNO; Nit
Keywords: SERCA2a; Phospholamban; Protein phosphatase 1; Decoy; Peptide;
Keywords: AF; atrial fibrillation; AKAP; A-kinase-anchoring protein; AP; action potential; β-AR; β-adrenoceptor; CaMKII; Ca2 +/calmodulin-dependent protein kinase type-II; CKIP-1; casein kinase-2 interacting protein-1; cMyBP-C; cardiac myosin-binding protein-C;
Inotropes
Keywords: acute heart failure; cardiogenic shock; inotrope; ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; LV; left ventricle; LVEDP; left ventricular end-diastolic pressure; NE; norepinephrine; PDE; phosphodiesterase; SERCA2a; sarco/endoplasmic
Designer Approaches for G Protein-Coupled Receptor Modulation for Cardiovascular Disease
Keywords: biased ligands; G protein-coupled receptor kinases; G protein-coupled receptors; AR; adrenergic receptor; AT1R; angiotensin II type 1A receptor; CRF; corticotropin-releasing factor; EGFR; epidermal growth factor receptor; ERK1/2; extracellular signal-
Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II
Keywords: CaMKII; Ca2+/calmodulin-dependent protein kinase II; CSE; cystathionine γ-lyase; H2O2; hydrogen peroxide; H2S; hydrogen sulfide; ISO; isoprenaline; mPTP; mitochondrial permeability transition pore; NaHS; sodium hydrogen sulfide; NO; nitric oxide; PAG; D,
Phospholamban regulates nuclear Ca2+ stores and inositol 1,4,5-trisphosphate mediated nuclear Ca2+ cycling in cardiomyocytes
Keywords: Phospholamban; Calcium signaling; Cardiomyocyte; Nuclear membranes; 1,4,5-Trisphosphate receptor; Sarcoplasmic reticulum Ca2+ cycling; Nuclear Ca2+ dynamics; CM; cardiomyocyte; ER; endoplasmic reticulum; Fab; the Fab fragment of the monoclonal anti-PLB an
HAX-1 regulates SERCA2a oxidation and degradation
Keywords: Heart; HAX-1; SERCA2a; NOX4; Oxidative modification; Ischemia reperfusion; Proteolysis;
SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction
Keywords: Intracellular calcium; Ischemic ventricular arrhythmia; SNX17; SERCA2a;
Impaired Ca2+ cycling of nonischemic myocytes contributes to sarcomere dysfunction early after myocardial infarction
Keywords: Myocardial infarction; Remote myocardium; SERCA2a; Phospholamban; Myocyte calcium cycling; Sarcomere function;
The chemical biology of HNO signaling
Keywords: Nitroxyl; Azanone; Thiols; Nitrogen oxides; RSSH; hydropersulfides; DTT; dithiothreitol; GPx; glutathione peroxidase; BDE; bond dissociation energy; NHE; normal hydrogen electrode; metmyoglobin; MbFe3+; methemoglobin; HbFe3+; ferrous myoglobin; MbFe2+; sG
The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury
Keywords: DIAPH1; diaphanous 1; EGR1; early growth response 1; F actin; filamentous (F) actin; Fos; gene for c-Fos; G actin; globular (G) actin; GSK3B; glycogen synthase kinase 3 beta; Ex vivo I/R; ex vivo ischemia/reperfusion; H/R; hypoxia/reoxygenation; I/R; isch
SERCA2a: A potential non-invasive biomarker of cardiac allograft rejection
Keywords: SERCA2a; cardiac rejection; endomyocardial biopsies; non-invasive; transplant;
Sub-cellular localization specific SUMOylation in the heart
Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d
Post-translational Modifications in Heart Failure: Small Changes, Big Impact
Keywords: Heart failure; Post-translational modifications; SUMO; SERCA2a
Serca2a and Na+/Ca2 + exchanger are involved in left ventricular function following cardiac remodelling of female rats treated with anabolic androgenic steroid
Keywords: Nandrolone decanoate; Resistive exercise; Left ventricular hypertrophy; Cardiac function; SERCA2a; NCX
Mesenchymal stem cells suppress cardiac alternans by activation of PI3K mediated nitroso-redox pathway
Keywords: Mesenchymal stem cells; Alternans; Oxidative stress; Arrhythmia; SERCA2a;
Association of cardiac injury with iron-increased oxidative and nitrative modifications of the SERCA2a isoform of sarcoplasmic reticulum Ca2+-ATPase in diabetic rats
Keywords: Iron; Diabetic heart complications; Tyrosine nitration; SERCA2a; DFO; deferoxamine; DNP; dinitrophenol; DTT; dithiothreitol; HFD; high-fat diet; iNOS; inducible nitric oxide synthase; i.p.; intraperitoneally; NO; nitric oxide; NPD; normal pellet diet; ONO
Phospholamban pentamers attenuate PKA-dependent phosphorylation of monomers
Keywords: Phospholamban; SERCA2a; Protein kinase A; Sarcoplasmic reticulum;
Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction
Keywords: Apo; apolipoprotein; CKD; chronic kidney disease; EDPVR; end-diastolic pressure-volume relationship; ESPVR; end-systolic pressure-volume relationship; HDL; high-density lipoprotein; LDL; low-density lipoprotein; LOX-1; lectin-like oxidized LDL recepto
Left ventricular diastolic dysfunction in Nrf2 knock out mice is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function
Keywords: BP; blood pressure; CO; cardiac output; DP; developed pressure; DT; deceleration time; FMD; flow-mediated dilation; GC; guanylyl cyclase; IVRT; isovolumic relaxation time; KO; knock out; LV; left ventricular; MVET; mitral valve ejection time; Nrf2; nuclea
Exendin-4 improves cardiac function in mice overexpressing monocyte chemoattractant protein-1 in cardiomyocytes
Keywords: Glp1; Glucagon-like peptide-1; Glp1r; Glp1 receptor; Ex4; Exendin-4; MCP1; monocyte chemoattractant protein-1; MCPIP; MCP1-induced protein; ER; endoplasmic reticulum; GRP78; glucose-regulated protein 78Â kDa; CHOP; CCAAT/-enhancer-binding protein homologo
S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death
Keywords: BIAM; Biotin iodoacetamide; DMEM; Dulbecco's modified eagle medium; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GFP; Green fluorescent protein; GSNO; S-nitrosoglutathione; HEK-293; Homo sapiens embryonic kidney; H2O2; Hydrogen peroxide; IPC; Ischemic
p38α regulates SERCA2a function
Keywords: Phospholamban; SERCA2a; p38; Cardiac contractilityAMVM, adult mouse ventricular myocyte; ARVM, adult rat ventricular myocyte; dn, dominant negative; ET-1, endothelin-1; GRK, G protein coupled receptor kinase; I-1, inhibitor-1; MAPK, mitogen-activated prot
A cell-penetrating phospholamban-specific RNA aptamer enhances Ca2Â + transients and contractile function in cardiomyocytes
Keywords: SR; sarcoplasmic reticulum; SERCA2a; sarco(endo)plasmic reticulum Ca2Â +-ATPase 2a; PLN; phospholamban; PKA; cAMP-dependent protein kinase; SELEX; systematic evolution of ligands by exponential enrichment; Aptamer; Calcium signaling; Cardiac sarcoplasmic
Differential effects of S100 proteins A2 and A6 on cardiac Ca2Â + cycling and contractile performance
Keywords: HF; heart failure; Ca2Â +; calcium; SERCA2a; sarcoplasmic reticulum Ca2Â + ATPase 2a; RyR; ryanodine receptor Ca2Â + release channel; CSQ; calsequestrin; PLN; phospholamban; NCX; Na+/Ca2Â + exchanger; SL; sarcomere length; LAD; left anterior descending ar
MicroRNA-328 as a regulator of cardiac hypertrophy
Keywords: Cardiac hypertrophy; miR-328; SERCA2a; Calcineurin; NFATc3;
CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury
Keywords: AC3-I; Ca2+-calmodulin kinase II-inhibitory peptide; Ca2+; Calcium; CaMKII; Ca2+-calmodulin kinase II; GAPDH; Glyceraldehyde 3-phosphate dehydrogenase; I/R; Ischemia/reperfusion; LAD; Left anterior descending; LDH; Lactodehydrogenase; MI; Myocardial infar
Safety and efficacy of high-dose adeno-associated virus 9 encoding sarcoplasmic reticulum Ca2+ adenosine triphosphatase delivered by molecular cardiac surgery with recirculating delivery in ovine ischemic cardiomyopathy
Keywords: 18; 22; 29; 30; AAV; adeno-associated virus; HF; heart failure; LV; left ventricular; MCARD; molecular cardiac surgery with recirculating delivery; MRI; magnetic resonance imaging; NAb; neutralizing antibody; ROS; reactive oxygen species; SERCA2a; sarcopl
TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis
Keywords: Remodeling; esophagus; eosinophils; smooth muscle; TGF-β; phospholamban; EMF; Esophageal myofibroblast; EoE; Eosinophilic esophagitis; ESM; Esophageal smooth muscle; FACS; Fluorescence-activated cell sorting; hpf; High-power field; PLN; Phospholamban; Se
CaV1.2 signaling complexes in the heart
Keywords: LTCC; L-type Ca2 + channel; βAR; β-adrenergic receptor; EPR; E type prostaglandin receptor; RyR2; type 2 ryanodine receptor; AC; adenylyl cyclase; PDE; phosphodiesterase; PP; protein phosphatase; AKAP; A kinase anchoring protein; PKA; protein kinase A;
Gestational exposure to diethylstilbestrol alters cardiac structure/function, protein expression and DNA methylation in adult male mice progeny
Keywords: Diethylstilbestrol; Calsequestrin 2; SERCA2a; Echocardiography; DNA methylation; CpG island
The novel compound liguzinediol exerts positive inotropic effects in isolated rat heart via sarcoplasmic reticulum Ca2Â + ATPase-dependent mechanism
Keywords: Liguzinediol; SERCA2a; Ryanodine receptor; L-type calcium channel; Calcium transient;
Cardiac mechanoenergetics for understanding isoproterenol-induced rat heart failure
Keywords: Mechanoenergetics; ESPVR and EDPVR; VO2–PVA relation; PVA-independent VO2-eEmax relation; Basal metabolism; Isoproterenol-induced hypertrophy model; SERCA2a
Cardiovascular effects and molecular targets of resveratrol
Keywords: 4-HNE; 4-hydroxy-2-nonenal; ADMA; asymmetric dimethylarginine; AMPK; AMP-activated protein kinase; ApoE; apolipoprotein E; ARE; antioxidant response element; BH4; tetrahydrobiopterin; Cav-1; caveolin-1; COX-1; cyclooxygenase 1; CREB; cAMP response element
The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase
Keywords: SR; sarcoplasmic reticulum; SERCA2a; Cardiac sarcoplasmic reticulum Ca2 +-ATPase; PLN; phospholamban; βAR; β-adrenergic receptor; DCM; dilated cardiomyopathy; NKA; Na/K ATPase; Heart failure; Mutation; Calcium cycling; Phospholamban; SERCA;
Compatibility art of traditional Chinese medicine: From the perspective of herb pairs
Keywords: ADME; absorption, distribution, metabolism and excretion; APL; acute promyelocytic leukemia; CHM; Chinese herbal medicine; CYP2E1; Cytochrome P450 2E1; dl-THP; dl-tetrahydropalmatine; HIF1α; hypoxia-inducible factor-1alpha; HUVECs; human umbilical vascul
CaMKII regulation of phospholamban and SR Ca2+ load
Keywords: CaMKII; Phospholamban phosphorylation; Sarcoplasmic reticulum; Ryanodine receptors; Acidosis; Ischemia/reperfusion; β-ARS; β1-adrenergic receptor stimulation; CaMKII; Ca2+-calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate; Epac