دانلود مقالات ISI درباره siRNA، RNA تداخل کوچک + ترجمه فارسی

تحویل درمان هدفمند با استفاده از اکسیوزون های مهندسی و کاربرد آن در بیماری های قلبی عروقی

Targeted therapeutic delivery using engineered exosomes and its applications in cardiovascular diseases

Keywords: siRNA، RNA تداخل کوچک; miRNA, microRNA; siRNA, small interference RNA; lncRNA, long non-coding RNA; ILVs, intraluminal vesicles; MVBs, multivesicular bodies; CD, cluster of differentiation; HSP, heat shock protein; SDCBP, syndecan binding protein; EBV, Epstein–Barr virus; RVG,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Downregulation of miR-18a induces CTGF and promotes proliferation and migration of sodium hyaluronate treated human corneal epithelial cells

Keywords: siRNA، RNA تداخل کوچک; miRNA, microRNA; siRNA, small interference RNA; CTGF, connective tissue growth factor; SH, sodium hyaluronate; HCECs, human corneal epithelial cells; KGM, keratinocyte growth medium; PBS, phosphate-buffered saline; Arf6, ADP-ribosylation factor 6; CDC42,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cytotoxicity mechanism of α-MMC in normal liver cells through LRP1 mediated endocytosis and JNK activation

Keywords: siRNA، RNA تداخل کوچک; α-MMC, α-momorcharin; α2-M, α2-macroglobulin; LRP-1, low-density lipoprotein receptor-related protein-1; siRNA, small interference RNA; TCS, trichosanthin; JNK, Jun N-terminal kinase; RIPs, ribosome inactivating proteins; FITC, fluorescein isothiocyanate;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53

Keywords: siRNA، RNA تداخل کوچک; WWP1, WW domain containing E3 ubiquitin protein ligase 1; HCC, hepatocellular carcinoma; FBS, fetal bovine serum; AFP, α-fetoprotein; 18S rRNA, 18S ribosomal ribonucleic acid; siRNA, small interference RNA; GAPDH, glyceraldehyde-3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Transient expression of siRNA targeted against the TYLCV AV1, AC1 and AC3 genes for high resistance in tomato

Keywords: siRNA، RNA تداخل کوچک; TYLCV, tomato yellow leaf curl virus; RNAi, RNA interference; NCBI, National Center for Biotechnology Information; siRNA, small interference RNA; ORF, open reading frames; PDS, phytoene desaturaseRNA silencing; Tomato yellow leaf curl virus; Transient exp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6

Keywords: siRNA، RNA تداخل کوچک; USP, ubiquitin-specific protease; DUB, deubiquitinating enzyme; ER, endoplasmic reticulum; ERAD, ER-associated degradation; E3, E3 ubiquitin ligase; NPT II, neomycin phosphotransferase II; FBS, fetal bovine serum; siRNA, small interference RNA; NEM, N-eth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway

Keywords: siRNA، RNA تداخل کوچک; Cdk, Cyclin-dependent kinase; DN, Diabetic nephropathy; Egr, Early growth response; ERK, Extracellular signal-regulated kinase; MEK, Mitogen-activated protein kinase/ERK kinase; siRNA, Small interference RNA; TGF-β1, Transforming growth factor-β1.Cdk5; TG

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Celecoxib antagonizes the cytotoxic effect of cisplatin in human gastric cancer cells by decreasing intracellular cisplatin accumulation

Keywords: siRNA، RNA تداخل کوچک; COX, cyclooxygenase; CTR1, copper transporter 1; NSAIDs, nonsteroidal anti-inflammatory drugs; PGE2, Prostaglandin E2; PARP, poly (ADP-ribose) polymerase; siRNA, small interference RNA; SC-236, 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]ben

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

RNA interference targeting E637K mutation rescues hERG channel currents and restores its kinetic properties

Keywords: siRNA، RNA تداخل کوچک; hERG, human ether-a-go-go-related gene; IKr, rapidly activating delayed rectifier potassium current; LQTS, long QT syndrome; LQT2, long QT syndrome type 2; RNAi, RNA interference; siRNA, small interference RNA; V1/2, half-maximal voltage valueGene therapy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation

Keywords: siRNA، RNA تداخل کوچک; miRNAs, microRNAs; siRNA, small interference RNA; SOC, serious ovarian cancer; OSE, ovarian surface epithelium; Ob, obesity gene; OB-R, leptin receptor; STAT5, signal transducers and activators of transcription-5; ECL, enhanced chemiluminescence; JAK, Jan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of Drosophila-virus interaction

Keywords: siRNA، RNA تداخل کوچک; miRNA, microRNA; siRNA, small interference RNA; piRNA, piwi-interacting RNA; mRNA, messenger RNA; AMP, antimicrobial peptide; NF-κB, nuclear factor-kappa B; VSR, viral suppressor of RNA; IκB, inhibitor kappa BMicroRNA; Virus; Innate immunity; Drosophila m

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

UTF1 deficiency promotes retinoic acid-induced neuronal differentiation in P19 embryonal carcinoma cells

Keywords: siRNA، RNA تداخل کوچک; BrdU, 5′-bromo-doxy-uridine; DMSO, dimethyl sulfoxide; EBs, embryoid bodies; EC, embryonal carcinoma; ES, embryonic stem; IF, immuno-fluorescence; RA, retinoic acid; shRNA, small hairpin RNA; siRNA, small interference RNA; UTF1, undifferentiated embryonic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Genistein enhances the effect of trichostatin A on inhibition of A549 cell growth by increasing expression of TNF receptor-1

Keywords: siRNA، RNA تداخل کوچک; DMSO, Dimethyl sulfoxide; RT-PCR, Reverse transcription PCR; siRNA, small interference RNA; TNFR-1, TNF receptor-1; TSA, Trichostatin AGenistein; Trichostatin A; TNF receptor-1; A549 cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice

Keywords: siRNA، RNA تداخل کوچک; OGG-1, 8-oxoguanine-DNA glycosylase; ROS, reactive oxygen species; KO, knockout mice; WT, wild type; OVA, ovalbumin; TBARS, thiobarbituric acid-reactive substances; siRNA, small interference RNA; H2DCF-DA, dichlorodihydrofluorescein diacetate; HDM, house

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic Variants, Cardiovascular Risk and Genome-Wide Association Studies

Keywords: siRNA، RNA تداخل کوچک; CAD, coronary artery disease; CNV, copy number variation; CRF, cardiovascular risk factor; GWAS, genome-wide association studies; MI, myocardial infarction; RR, risk ratio; SiRNA, small interference RNA; SNPs, single nucleotide polymorphismCardiovascular

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes

Keywords: siRNA، RNA تداخل کوچک; Shh, Sonic hedgehog; Runx2, Runt related transcription factor 2; BMP, bone morphogenic protein; GAG, glycosaminoglycan; RNAi, RNA interference; siRNA, small interference RNA; Hif-1, hypoxia-inducible factor 1; SMMD, spondylo-megaepiphysial-metaphysial dys

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Evidence for Recycling of External Guide Sequences during Cleavage of Bipartite Substrates In vitro by Reconstituted Archaeal RNase P

Keywords: siRNA، RNA تداخل کوچک; targeted RNA cleavage; turnoverEGS, external guide sequence; pre-tRNA, precursor tRNA; RPR, RNase P RNA; RPP, RNase P protein; siRNA, small interference RNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Toll-like receptor 2-mediated sequential activation of MyD88 and MAPKs contributes to lipopolysaccharide-induced sp-a gene expression in human alveolar epithelial cells

Keywords: siRNA، RNA تداخل کوچک; AP-1, activator protein-1; EMSA, electrophoretic morbility shift assay; LPS, lipopolysaccharide; JNK1, c-Jun NH2 terminal kinase 1; MEK4, mitogen-activated protein kinase 4; MyD88, myeloid differentiation factor 88; siRNA, small interference RNA; SPs, sur

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

MiR-101 regulates HSV-1 replication by targeting ATP5B

Keywords: siRNA، RNA تداخل کوچک; miRNA, microRNA; HSV-1, herpes simplex virus-1; UTR, untranslated region; ATP5B, ATP synthase subunit beta; ASO, antisense oligonucleotide; CPE, cytopathogenic effect; MOI, multiplicity of infection; siRNA, small interference RNA; EGFP, enhanced green flu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Post-transcriptional gene silencing by RNA interference in non-mammalian vertebrate systems: Where do we stand?

Keywords: siRNA، RNA تداخل کوچک; RNAi, RNA interference; TGS, transciptional gene silencing; PTGS, post-transcriptional gene silencing; ODN, oligodeoxyribonucleic acids; siRNA, small interference RNA; miRNA, microRNA; esiRNA, endoribonuclease-digested RNA; IFN, interferon; RISC, RNAi-ind

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells

Keywords: siRNA، RNA تداخل کوچک; CT, threshold of cycle; DMMB, 1,9-dimethylmethylene blue; ECM, extracellular matrix; HA, hyaluronic acid; GAG, glycosaminoglycans; qPCR, quantitative real-time PCR; RHAMM, receptor of HA mediated motility; siRNA, small interference RNA; UGDH, UDP-glucose

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Lipoteichoic acid enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, PKCδ and c-Src dependent pathways

Keywords: siRNA، RNA تداخل کوچک; LTA, lipoteichoic acid; PGN, peptidoglycan; siRNA, small interference RNA; LPS, lipopolysaccharide; IL, interleukin; TNF, tumor necrosis factor; RA, rheumatoid arthritis; RASF, rheumatoid arthritis synovial fibroblasts; TLR, Toll-like receptor; ODN, oligo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Multiple shRNAs driven by U6 and CMV promoter enhances efficiency of antiviral effects against foot-and-mouth disease virus

Keywords: siRNA، RNA تداخل کوچک; FMD, foot-and-mouth disease; FMDV, foot-and-mouth disease virus; GFP, green fluorescent protein; siRNA, small interference RNA; shRNA, short hairpin RNA; RNAi, RNA interference; miRNA, microRNA; mRNA, messenger RNAs; Pol II, RNA polymerase II; Pol III, RN

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Enhancement of dendritic cell-based vaccine potency by anti-apoptotic siRNAs targeting key pro-apoptotic proteins in cytotoxic CD8+ T cell-mediated cell death

Keywords: siRNA، RNA تداخل کوچک; siRNA, small interference RNA; DC, dendritic cell; LAMP-1, lysosome-associated membrane protein type 1; HPV-16, human papilloma virus-16; CTL, cytotoxic T lymphocyte; RNAi, RNA interference; FITC, fluorescein isothiocyanate; PE, Phycoerythrin; MHC, major

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells

Keywords: siRNA، RNA تداخل کوچک; 5-Fluorouracil (5-Fu), 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors; PI3K, phosphatidylinositol 3-kinase; GSK3β, glycogen synthase kinase 3 beta; siRNA, small interference RNA; pAkt Ser473, phosphorylation of Akt on residue Ser473; pAkt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

TMEM74, a lysosome and autophagosome protein, regulates autophagy

Keywords: siRNA، RNA تداخل کوچک; MDC, monodansylcadaverine; siRNA, small interference RNA; LC3, microtubule-associated protein 1 light chain 3; GFP, green fluorescent protein; FCS, fetal bovine serum; TEM, transmission electron microscopy; EST, expressed sequence tag; PCR, polymerase cha

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Targeting alpha-fetoprotein represses the proliferation of hepatoma cells via regulation of the cell cycle

Keywords: siRNA، RNA تداخل کوچک; Adv, Adenovirus; AFP, Alpha-fetoprotein; ASO, antisense oligonucleotide; MOI, multiplicity of infection; siRNA, small interference RNA; shRNA, short hairpin RNA; SCID, Severe Combined ImmunodeficiencyLiver cancer; siRNA; Cell cycle; Recombinant adenovirus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-κB pathways

Keywords: siRNA، RNA تداخل کوچک; DCs, dendritic cells; BMDCs, bone marrow-derived DCs; BMMs, bone marrow-derived macrophages; siRNA, small interference RNA; NGF, nerve growth factor; p75NTR, p75 neurotrophin receptor; p140TrkA, p140 tyrosine protein kinase receptorDendritic cells; Nerve

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling

Keywords: siRNA، RNA تداخل کوچک; MSCs, mesenchymal stem cells; SCID, severe combined immunodeficiency; siRNA, small interference RNA; Dkk-1, dickkopf-1; hTERT, human telomerase reverse transcriptase; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideBreast cancer; Mesenchy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet

Keywords: siRNA، RNA تداخل کوچک; EMSA, electrophoretic mobility shift assay; hnRNPG, heterogeneous nuclear ribonucleoprotein G; RBMX, RNA-binding motif protein on the X chromosome; RBMY, RNA-binding motif protein on the Y chromosome; RNAi, RNA interference; siRNA, small interference RNA;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Apoptosis induced by BIK was decreased with RNA interference of caspase-12

Keywords: siRNA، RNA تداخل کوچک; siRNA, small interference RNA; ER, endoplasmic reticulum; MMP, mitochondrial membrane potential; RNAi, RNA interferenceBIK; Caspase-12; Apoptosis; RNAi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Targeted deletion of the osteoclast protein-tyrosine phosphatase (PTP-oc) promoter prevents RANKL-mediated osteoclastic differentiation of RAW264.7 cells

Keywords: siRNA، RNA تداخل کوچک; PTP, protein-tyrosine phosphatase; TRACP, tartrate-resistant acid phosphatase; PD-, phosphatase-deficient-; siRNA, small interference RNA; DMEM, Dulbecco’s modified Eagle’s medium; RANK, receptor activator of NFκB; RANKL, RANK ligand; FBS, fetal bovine se

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth

Keywords: siRNA، RNA تداخل کوچک; CP, cortical plate; IZ, intermediate zone; LIM, specific double zinc finger motif; PCP, planar cell polarity; PCR, polymerase chain reaction; RT, reverse transcription; siRNA, small interference RNA; SP, subplate; VZ, ventricular zoneCortical neuron; Neur

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Chromosomal position, structure, expression, and requirement of genes for chicken transcription factor IIA

Keywords: siRNA، RNA تداخل کوچک; GTF, general transcription factor; TFIIA, transcription factor IIA; TBP, TATA-binding protein; CRS, cleavage recognition site; AA, amino acid; FISH, fluorescence in situ hybridization; RNAi, RNA interference; siRNA, small interference RNA; GAPDH, glyceral

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

RNA interference as a novel and powerful tool in immunopharmacological research

Keywords: siRNA، RNA تداخل کوچک; RNAi, RNA interference; siRNA, Small interference RNA; miRNA, microRNA; dsRNA, Double-stranded RNA; RISC, RNA-induced silencing complex; shRNA, Short hairpin RNA; MREs, miRNA recognition elements; PILs, Pegylated immunoliposomes; PEG, PolyethyleneglycolRN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Subcellular localization of Daxx determines its opposing functions in ischemic cell death

Keywords: siRNA، RNA تداخل کوچک; ASK1, apoptosis signal-regulating kinase 1; CH, chemical hypoxia; JNK, c-Jun N-terminal kinase; LMB, leptomycin B; siRNA, small interference RNA; PML-NB, promyelocytic leukemia protein-nuclear body; RASSF1C, Ras-associated domain family 1C protein; scRNA,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-κB-dependent pathway in human lung cancer cells

Keywords: siRNA، RNA تداخل کوچک; SDF-1, stromal-derived factor-1; ERK, extracellular signal regulated kinase; IKKα/β, IκB kinase α/β; NSCLCs, non-small cell lung cancers; ECM, extracellular matrix; siRNA, small interference RNA; RT-PCR, mRNA analysis by reverse transcriptase-polymerase c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Cellular knock-down of quinone reductase 2: A laborious road to successful inhibition by RNA interference

Keywords: siRNA، RNA تداخل کوچک; Quinone reductase 2; RNA interference; Short hairpin RNA; HT22; TransfectionRNAi, RNA interference; siRNA, small interference RNA; QR2, NRH:quinone oxidoreductase 2; BNAH, dihydrobenzylnicotinamide; NRH, dihydronicotinamide riboside; NQO1, NAD(P)H:quinone

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه