Perlecan signaling: Helping hedgehog stimulate prostate cancer growth
Keywords: صدای جیر جیر; Cancer; Sonic hedgehog; Perlecan; Medicine
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Sonic hedgehog mRNA expression by real-time quantitative PCR in normal and tumor tissues from colorectal cancer patients
Keywords: صدای جیر جیر; Sonic hedgehog; Real-time quantitative PCR; Colorectal cancer
Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration
Keywords: صدای جیر جیر; Sonic hedgehog; Gastric mucosal cells; Intracellular calcium; Cellular proliferation; Extracellular signal-regulated kinase
Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation
Keywords: صدای جیر جیر; PACAP; VIP; PAC1; VPAC1; VPAC2; Sonic hedgehog; Oligodendrocyte progenitors; Proliferation; Gene expression; CNPase; ptc1; gli1
Forced chondrocyte expression of sonic hedgehog impairs joint formation affecting proliferation and apoptosis
Keywords: صدای جیر جیر; Sonic hedgehog; Chondrocytes; Transgenic mice; Joint formation; Proliferation; Apoptosis
Intrinsic and extrinsic inhibition of oligodendrocyte development by rat retina
Keywords: صدای جیر جیر; Oligodendrocytes; Retina; Stem cells; BMP4; Sonic hedgehog
Hedgehog signaling in small-cell lung cancer: Frequent in vivo but a rare event in vitro
Keywords: صدای جیر جیر; Small-cell lung cancer; SCLC; Hedgehog signaling pathway; Cyclopamine; siRNA; HH; hedgehog; HHIP; hedgehog interacting protein; NSCLC; non-SCLC; PTCH; Patched; RNAi; RNA interference; SCLC; small-cell lung cancer; SHH; Sonic hedgehog; siRNA; small interfe
Regulation of Gremlin expression in the posterior limb bud
Keywords: صدای جیر جیر; Gremlin; Bmp; Shh; Fgf; Bone morphogenetic protein; Sonic hedgehog; Fibroblast growth factor; Limb bud; oligozeugodactyly
Hippi is essential for node cilia assembly and Sonic hedgehog signaling
Keywords: صدای جیر جیر; Cilia; Hippi; Huntington disease; Left–right patterning; Sonic hedgehog
Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function
Keywords: صدای جیر جیر; Indian hedgehog; Sonic hedgehog; Cranial base; Synchondrosis; Growth plate; Skeletogenesis; Extracellular matrix; Aggrecan; BMPs
Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud
Keywords: صدای جیر جیر; Blimp-1; Limb bud; Zebrafish; Pectoral fin; tbx5; fgf24; fgf10; Apical ectodermal ridge; Zone of polarizing activity; Sonic hedgehog;
The homeobox gene irx1a is required for the propagation of the neurogenic waves in the zebrafish retina
Keywords: صدای جیر جیر; Zebrafish; Retinogenesis; Wave propagation; Iroquois; Sonic hedgehog
Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2
Keywords: صدای جیر جیر; Fibroblast growth factor-2; Oligodendrocyte; Olig2; PDGFRα; Sonic hedgehog; Nkx2.1; Dlx2; Patched1; Myelin
Mouse Rab23 regulates Hedgehog signaling from Smoothened to Gli proteins
Keywords: صدای جیر جیر; Sonic Hedgehog; Rab23; Smoothened; Gli2; Gli3; Neural tube; Patterning
Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives
Keywords: صدای جیر جیر; Retinoids; Lung; Stomach; Liver; Fgf10; Sonic hedgehog; Hox genes; Tbx genes
Functional compensation in Hedgehog signaling during mouse prostate development
Keywords: صدای جیر جیر; Sonic Hedgehog; Indian Hedgehog; Prostate development; Gli1; Gli2; Gli3; Budding; Differentiation; UGS; Functional redundancy
Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling
Keywords: صدای جیر جیر; Gli1; Gli2; Gli3; Sonic Hedgehog; Transcription factors; Mouse embryonic fibroblasts
The presumptive floor plate (notoplate) induces behaviors associated with convergent extension in medial but not lateral neural plate cells of Xenopus
Keywords: صدای جیر جیر; Convergence and extension; Mediolateral intercalation; Cell behavior; Protrusive activity; Transgenesis; Specification; Notoplate; Floor plate; Sonic hedgehog; F-spondin; Xslug; Neural plate; Notoplate/Neural plate boundary; Xenopus laevis;
The role of megalin (LRP-2/Gp330) during development
Keywords: صدای جیر جیر; Megalin; Development; Sonic hedgehog; RAP; LDLR; Cholesterol; Endocytosis; HSPGs; Cubilin; Expression patterns
Regulated expression pattern of gremlin during zebrafish development
Keywords: صدای جیر جیر; Can domain; Zebra fish embryo; Dorsoventral axis; Somitogenesis; Fibroblast growth factor; Sonic hedgehog;
Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation
Keywords: صدای جیر جیر; Palate; Cleft palate; Epithelial-mesenchymal transformation; Fate-mapping; Sonic hedgehog;
Hedgehog signaling pathway as a therapeutic target in breast cancer
Keywords: صدای جیر جیر; Hedgehog ligands; Sonic hedgehog; Patched1; Smoothened; Glis; Cyclopamine; Mammary gland; 5-E1 antibody;
Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling
Keywords: صدای جیر جیر; Cadmium; Postaxial forelimb ectrodactyly; Sonic hedgehog; Polarizing activity; Gli/luciferase reporter; Patched; Fgf8; Gli3;
Identification of protogenin, a novel immunoglobulin superfamily gene expressed during early chick embryogenesis
Keywords: صدای جیر جیر; Chick; Protogenin; Immunoglobulin superfamily; Chromosomal localization; DCC (Deleted in Colorectal Cancer); Neogenin; Nope; Punc; Gene expression; Neural development; Sonic hedgehog; Ventricular zone;
Yolk sac cholesteryl ester secretion rates can be manipulated in the Golden Syrian hamster: Effect of yolk sac cholesterol concentrations
Keywords: صدای جیر جیر; Smith-Lemli-Opitz syndrome; SLOS; 3β-hydroxysteroid-delta7-reductase; Î7 reductase; apolipoprotein; apo; Eagle's Basal Media; EBM; lactate dehydrogenase; LDH; Sonic hedgehog; Shh; Fetus; Lipoprotein; Smith-Lemli-Opitz syndrome; Visceral endoderm
Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Keywords: صدای جیر جیر; sonic hedgehog; hair follicle; androgenetic alopecia;
Satellite cells, myoblasts and other occasional myogenic progenitors: Possible origin, phenotypic features and role in muscle regeneration
Keywords: صدای جیر جیر; BMP2; bone morphogenetic protein 2; GFP; green fluorescent protein; HSC; hematopoietic stem cell; MSC; mesoderm stem cell (referred to as non hematopoietic); PKC; protein kinase C; Shh; sonic hedgehog; SP; side population; TGFβ; transforming growth facto
Mesenchymal-epithelial interactions in the skin: Aiming for site-specific tissue regeneration
Keywords: صدای جیر جیر; GM-CSF; granulocyte macrophage colony stimulating factor; KGF; keratinocyte growth factor; bFGF; basic fibroblast growth factor; BMP; bone morphogenetic protein; TGF-β; transforming growth factor-β; TNF-α; tissue necrosis factor-α; RA; retinoic acid;
Sonic Hedgehog Induces Epidermal Growth Factor Dependent Matrix Infiltration in HaCaT Keratinocytes
Keywords: صدای جیر جیر; differentiation; epidermal growth factor; infiltration; keratinocytes; sonic hedgehog;
Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons
Keywords: صدای جیر جیر; Patched; Sonic hedgehog; Basal cell carcinoma; Medulloblastoma; Alternative splicing;
Highly conserved regulatory elements around the SHH gene may contribute to the maintenance of conserved synteny across human chromosome 7q36.3
Keywords: صدای جیر جیر; Regulatory elements; Enhancers; Fugu; Sonic Hedgehog; Shh; Zebrafish;
Gli1 is not required for Pdgfrα expression during mouse embryonic development
Keywords: صدای جیر جیر; Pdgf receptor α; PdgfA; Gli; sonic hedgehog; Indian hedgehog; patched; mRNA expression pattern; embryonic development;
Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors
Keywords: صدای جیر جیر; Adenovirus; Viral vectors; Animal model; Gene therapy; 6-OHDA; Parkinson's disease; Dopamine; Transplant; Sonic hedgehog;
Sonic Hedgehog and Retinoic Acid are not sufficient to induce motoneuron generation in the avian caudal neural tube
Keywords: صدای جیر جیر; Chick; Neural tube; Ventral patterning; Motoneurons; Sonic Hedgehog; Retinoic Acid;
Emerging roles for TGF-β1 in nervous system development
Keywords: صدای جیر جیر; APP; Alzheimer β amyloid precursor protein; BMPs; bone morphogenetic proteins; CNS; central nervous system; ECM; extracellular matrix molecules; EGF; epidermal growth factor; FGF; fibroblast growth factor; GFAP; glial fibrillary acidic protein; GDNF; gli
Sonic hedgehog signaling in basal cell carcinomas
Keywords: صدای جیر جیر; Basal cell carcinoma; Ultraviolet; Mutation; Sonic hedgehog; Patched; Smoothened; BCC, basal cell carcinoma; SHH, sonic hedgehog; PTCH, patched; SMO, smoothened; HIP, hedgehog interacting protein; NBCC, nevoid basal cell carcinoma; XP, xeroderma pigmentos
Function and regulation of Alx4 in limb development: Complex genetic interactions with Gli3 and Shh
Keywords: صدای جیر جیر; Limb development; Alx4; Gli3; Antero-posterior patterning; Gene regulation; Sonic hedgehog; FGF4; Polydactyly;
Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs
Keywords: صدای جیر جیر; Pharyngeal pouches; Pharyngeal arches; Endoderm; Parathyroid; Thymus; Sonic hedgehog; Bone morphogenetic protein 4; Homeobox transcription factors; Gcm2; Foxn1;
Thalamic development induced by Shh in the chick embryo
Keywords: صدای جیر جیر; Chick; Neural tube; Diencephalon; Zona limitans intrathalamica; Sonic hedgehog; Thalamus; Secondary organizer;
Prenatal protracted irradiation at very low dose rate induces severe neuronal loss in rat hippocampus and cerebellum
Keywords: صدای جیر جیر; brain; development; prenatal low-dose irradiation; stereology; ANOVA; analysis of variance; bFGF; basic fibroblast growth factor; BrdU; bromodeoxyuridine; E; embryonic day; IGF; insulin growth factor; P; postnatal day; Shh; sonic hedgehog; SRS; systematic
Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
Keywords: صدای جیر جیر; Oligodendrocyte; Wnt; Dorsal factor; Canonical Wnt/β-catenin pathway; Glial differentiation; Sonic hedgehog;
Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant
Keywords: صدای جیر جیر; Sonic Hedgehog; Midbrain; Spinal cord; Floor plate; Motor neurons; Dopaminergic neurons; Notochord;
The Hedgehog Signalling Pathway in the Gastrointestinal Tract: Implications for Development, Homeostasis, and Disease
Keywords: صدای جیر جیر; Dhh; Desert hedgehog; EA/TEF; esophageal atresia/tracheo-esophageal fistula; Hh; hedgehog; HIP; hedgehog-interacting protein; Ihh; Indian hedgehog; N-Hhp; processed hedgehog; Ptc; patched; Smo; smoothened; Shh; Sonic hedgehog;
Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development
Keywords: صدای جیر جیر; Gli3; Extra-toes; Sonic hedgehog; Polydactyly; Limb development; Microarray; Jagged1; Pax9; Cdo;
Neuroprotective properties of cultured neural progenitor cells are associated with the production of sonic hedgehog
Keywords: صدای جیر جیر; sonic hedgehog; stem cells; neuroprotection; dopaminergic neurons; apoptosis; Parkinson's disease; AP; anteroposterior; bFGF; basic fibroblast growth factor; BrdU; bromodeoxyuridine; DIV; days in vitro; Dkk-1; Dick-kopf-1; DMEM; Delbeco's minimum esse
The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens
Keywords: صدای جیر جیر; Fgf10; FgfR2iiib; Bmp4; Bmp7; Sonic hedgehog; Patched; Prostate; Estrogen; Estradiol;
Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling
Keywords: صدای جیر جیر; Sonic hedgehog; Gli; Morphogen; Retinal ganglion cells; C17 cell line; Cyclopamine; Morpholino;
Pancreatic Cancer: Basic and Clinical Aspects
Keywords: صدای جیر جیر; CK; cytokeratin; COX; cyclooxygenase; DISC; death-inducing signaling complex; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FDR; fixed dose rate; 5-FU; 5-fluorouracil; GemOx; gemcitabine and oxaliplatin; MMP; matrix metalloproteina