Keywords: بازرسی مونتاژ اسپیندل; Mitosis; Kinetochore; Spindle assembly checkpoint; Kinase and phosphatase regulaton; Cancer;
مقالات ISI بازرسی مونتاژ اسپیندل (ترجمه نشده)
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Keywords: بازرسی مونتاژ اسپیندل; Cell cycle; Bistability; Restriction point; Spindle assembly checkpoint; Mitotic transitions;
Keywords: بازرسی مونتاژ اسپیندل; Spindly; Paclitaxel; Cancer cells; Spindle assembly checkpoint; Apoptosis; Cell cycle;
Keywords: بازرسی مونتاژ اسپیندل; ATM; ataxia-telangiectasia mutated; BCL2L1; BCL2 like 1; CGH; comparative genomic hybridization; CHK; checkpoint kinase 1; CIN; chromosomal instability; CNVs; copy number variations; DNMT3B; DNA methyltransferase 3B; DPPA3; developmental pluripotency asso
Keywords: بازرسی مونتاژ اسپیندل; AE; adverse event; AML; acute myeloid leukemia; APC; anaphase promoting complex; CLL; chronic lymphocytic leukemia; CPC; chromosomal passenger complex; CR; complete response; CRi; complete remission with incomplete blood count recovery; FDA; Food and Drug
Keywords: بازرسی مونتاژ اسپیندل; Systems biology; Kinetochore; Spindle assembly checkpoint; Spindle position checkpoint;
Keywords: بازرسی مونتاژ اسپیندل; chromokinesins; kinetochore; mitosis; mitosis with unreplicated genomes; spindle assembly checkpoint
LMO7 exerts an effect on mitosis progression and the spindle assembly checkpoint
Keywords: بازرسی مونتاژ اسپیندل; LMO7; MAD1; Actin filament; Mitosis; Spindle assembly checkpoint;
The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells
Keywords: بازرسی مونتاژ اسپیندل; CS1; Mitotic arrest; Spindle assembly checkpoint; Sister chromatid resolution; Microtubule inhibitor; Histone phosphorylation;
Mutational game changer: Chromothripsis and its emerging relevance to cancer
Keywords: بازرسی مونتاژ اسپیندل; SAC; spindle assembly checkpoint; APOBEC; apolipoprotein B mRNA-editing catalytic subunit; SNP; single-nucleotide polymorphism; array-CGH; comparative genomic hybridization; CLTP; chromothripsis-like pattern; SKY; spectral karyotyping; FISH; fluorescent i
The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential
Keywords: بازرسی مونتاژ اسپیندل; APC/C; anaphase-promoting complex/cyclosome; ASF1; antisilencing function 1; BRAF35; BRCA2-associated factor 35; BRCA2; breast cancer 2 protein; CAF-1; chromatin assembly factor 1; CR; cysteine rich; DCIS; ductal carcinoma in situ; DNMT3B; DNA methyltrans
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition
Keywords: بازرسی مونتاژ اسپیندل; Aurora kinase inhibitor; Anticancer agents; Docking study; SAC; spindle assembly checkpoint; CPC; chromosomal passenger complex; pHH3Ser10; phosphorylation on serine 10 of histone H3; MI; mitotic index;
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position
Keywords: بازرسی مونتاژ اسپیندل; Thieno[2,3-d]pyrimidine; Dithiocarbamate; Cytotoxicity; Probe; Target identification; Tubulin; Boc; tert-butyloxycarbonyl; CPT; camptothecin; DMF; N,N-dimethylformamide; DMSO; dimethyl sulphoxide; DSB; DNA double-strand break; EDCI; 1-ethyl-3-(3-dimethyla
Regular ArticlesLocation and functional analysis of the Aspergillus nidulans Aurora kinase confirm mitotic functions and suggest non-mitotic roles
Keywords: بازرسی مونتاژ اسپیندل; Aspergillus nidulans; Aurora kinase; Septation; Septal pore; Spindle assembly checkpoint; Spindle independent mitotic exit;
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity
Keywords: بازرسی مونتاژ اسپیندل; TTK; threonine tyrosine kinase; SAC; spindle assembly checkpoint; TNBC; triple-negative breast cancer; SPR; surface plasmon resonance; PDB; Protein Data Bank; PEG; polyethylene glycol; DMSO; dimethylsulfoxide; ATCC; American Type Culture Collection; targe
Transcriptional and post-transcriptional regulation of Cdc20 during the spindle assembly checkpoint in S. cerevisiae
Keywords: بازرسی مونتاژ اسپیندل; APC/C; the anaphase-promoting complex/cyclosome; SCF; the Skp1-cullin-F-box protein complex; SAC; the spindle assembly checkpoint; MCCs; mitotic checkpoint complexes; Protein degradation; Spindle assembly checkpoint; Cdc20; Post-transcriptional regulation
Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation
Keywords: بازرسی مونتاژ اسپیندل; CIN; chromosomal instability; CKIs; CDK inhibitors; DDC; sodium diethyldithiocarbamate trihydrate; GSK-3; glycogen synthase kinase 3; NAC; N-acetyl-L-cysteine; PCM; pericentriolar material; PCNT; pericentrin; ROS; reactive oxygen species; SAC; spindle ass
Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities
Keywords: بازرسی مونتاژ اسپیندل; Nek2 inhibitors; Imidazo[1,2-a]pyridine; Antitumor activity; Selectivity; Nek2; NIMA-related kinase 2; Nlp; ninein-like protein; SAC; spindle assembly checkpoint; Mad1/2; mitotic arrest deficient 1/2; Hec1; highly expressed in cancer 1; CIN; chromosome in
c-Rel in Epidermal Homeostasis: A Spotlight on c-Rel in Cell Cycle Regulation
Keywords: بازرسی مونتاژ اسپیندل; CDK; cyclin-dependent kinase; IKK; inhibitor of κB kinase; MCC; mitotic checkpoint complex; SAC; spindle assembly checkpoint; TNF; tumor necrosis factor;
Positive feedback promotes mitotic exit via the APC/C-Cdh1-separase-Cdc14 axis in budding yeast
Keywords: بازرسی مونتاژ اسپیندل; APC/C; anaphase-promoting complex or cyclosome; FEAR; Cdc14 early anaphase release; DAPI; 4â²,6-diamidino-2-phenylindole; GFP; green fluorescent protein; MEN; mitotic exit network; RFP; red fluorescent protein; SAC; spindle assembly checkpoint; SCF; Skp1
Fin1-PP1 Helps Clear Spindle Assembly Checkpoint Protein Bub1 from Kinetochores in Anaphase
Keywords: بازرسی مونتاژ اسپیندل; spindle assembly checkpoint; Bmh1; Fin1; PP1; FEAR pathway
Research paperAbsence of a conventional spindle mitotic checkpoint in the binucleated single-celled parasite Giardia intestinalis
Keywords: بازرسی مونتاژ اسپیندل; Giardia; Single-celled eukaryote; Spindle assembly checkpoint; Kinetochore; Mad2; Albendazole;
In silico analysis of deleterious single nucleotide polymorphisms in human BUB1 mitotic checkpoint serine/threonine kinase B gene
Keywords: بازرسی مونتاژ اسپیندل; Single nucleotide polymorphism (SNP); Pathogenic variants; Spindle assembly checkpoint; BUB1B gene;
Spindle assembly checkpoint is sufficient for complete Cdc20 sequestering in mitotic control
Keywords: بازرسی مونتاژ اسپیندل; Spindle assembly checkpoint; Anaphase promoting complex; MCC; Cdc20; Systems biology
The Tumor Suppressor Cdkn3 Is Required for Maintaining the Proper Number of Centrosomes by Regulating the Centrosomal Stability of Mps1
Keywords: بازرسی مونتاژ اسپیندل; Mps1; Cdkn3; centrosome duplication; spindle assembly checkpoint; mitosis
Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells
Keywords: بازرسی مونتاژ اسپیندل; PLK1, Polo-like kinase 1; NSCLC, non-small cell lung cancer; SAC, spindle assembly checkpoint; MCC, mitotic checkpoint complexPLK1; BI2536; Non-small cell lung cancer; Mitosis; Spindle assembly checkpoint; Mitotic catastrophe
Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy
Keywords: بازرسی مونتاژ اسپیندل; Mps1; Overexpression; Spindle assembly checkpoint; Tumorigenesis; Aneuploidy;
Cdh1 is an antagonist of the spindle assembly checkpoint
Keywords: بازرسی مونتاژ اسپیندل; APC/C; anaphase-promoting complex or cyclosome; MCC; mitotic checkpoint complex; SAC; spindle assembly checkpoint; Anaphase-promoting complex or cyclosome (APC/C); Cdc20; Cdh1; Spindle assembly checkpoint (SAC); Saccharomyces cerevisiae;
Deacetylation of the mitotic checkpoint protein BubR1 at lysine 250 by SIRT2 and subsequent effects on BubR1 degradation during the prometaphase/anaphase transition
Keywords: بازرسی مونتاژ اسپیندل; APC/C, anaphase promoting complex/cyclosome; SAC, spindle assembly checkpointSIRT2; Spindle assembly checkpoint; Microtubule inhibitors; BubR1; Acetylation/deacetylation
Sirt3 controls chromosome alignment by regulating spindle dynamics during mitosis
Keywords: بازرسی مونتاژ اسپیندل; Sirt3; Spindle assembly checkpoint; Chromosome alignment; Spindle dynamics;
Withaferin A modulates the Spindle Assembly Checkpoint by degradation of Mad2–Cdc20 complex in colorectal cancer cell lines
Keywords: بازرسی مونتاژ اسپیندل; Withaferin A; Spindle assembly checkpoint; Mad2; Cdc20; Chromosome instability
The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas
Keywords: بازرسی مونتاژ اسپیندل; Cervical squamous cell carcinomas; PinX1; Paclitaxel; Telomere dysfunction; Spindle assembly checkpoint
Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
Keywords: بازرسی مونتاژ اسپیندل; APC/C; Anaphase Promoting Complex/Cyclosome; AOM; azoxymethane; Bub3; budding uninhibited by benzimidazole protein 3; BubR1; bub1-related protein; Cdc20; cell division cycle 20; Cdh1; Cdc20 homologue protein 1; DMBA; 7,12-dimethylbenz-α-anthracene; Emi1;
Germline Mutations in the Spindle Assembly Checkpoint Genes BUB1 and BUB3 Are Risk Factors for Colorectal Cancer
Keywords: بازرسی مونتاژ اسپیندل; Cancer Predisposition; Spindle Assembly Checkpoint; Mosaic Variegated AneuploidyCRC, colorectal cancer; MVA, mosaic variegated aneuploidy; SAC, spindle assembly checkpoint
Chromosomal, metabolic, environmental, and hormonal origins of aneuploidy in mammalian oocytes
Keywords: بازرسی مونتاژ اسپیندل; Aneuploidy; Spindle assembly checkpoint; Meiosis; Oocyte; Aging; Cell cycle;
Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint
Keywords: بازرسی مونتاژ اسپیندل; Human papillomaviruses; E7 oncoprotein; Mitosis; Spindle assembly checkpoint; Cervical cancer; Cyclin B;
Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves
Keywords: بازرسی مونتاژ اسپیندل; AIF; apoptosis inducing factor; CDK; cyclin-dependent kinase; EGFR; epidermal growth factor receptor; HUVEC; human umbilical vein endothelial cells; PARP; poly(ADP-ribose)polymerase; PDGFR; platelet derived growth factor receptor; pH3Ser10; phosphorylated
The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint
Keywords: بازرسی مونتاژ اسپیندل; PARK2; Mitosis; Centrosome; Spindle assembly checkpoint; Self-interaction
Nucleoporins: Leaving the nuclear pore complex for a successful mitosis
Keywords: بازرسی مونتاژ اسپیندل; Nuclear pore complex; Nucleoporin; Spindle assembly checkpoint; Mitosis; Kinetochore; Cytokinesis
Nocodazole induces mitotic cell death with apoptotic-like features in Saccharomyces cerevisiae
Keywords: بازرسی مونتاژ اسپیندل; ROS; reactive oxygen species; APC/C; anaphase-promoting complex/cyclosome; SAC; spindle assembly checkpoint; PI; propidium iodide; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling; GFP; green fluorescent protein; Budding yeast;
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis
Keywords: بازرسی مونتاژ اسپیندل; Arecoline; Betel quid; Chromosomal aberrations; Genomic instability; Mitotic arrest; Spindle assembly checkpoint
SUMO Modification of DNA topoisomerase II: Trying to get a CENse of it all
Keywords: بازرسی مونتاژ اسپیندل; DNA topoisomerase II; SUMO; Sumoylation; Mitosis; Centromere; Kinetochore; Spindle assembly checkpoint; Aurora B/Ipl1; Chromosome segregation; Chromosome dynamics
The Ndc80 complex: Hub of kinetochore activity
Keywords: بازرسی مونتاژ اسپیندل; Kintochore; Centromere; Cancer; Aneuploidy; Hec1; Ndc80; Nuf2; Spc24; Spc25; Spindle assembly checkpoint; Microtubule
The spindle assembly checkpoint: Preventing chromosome mis-segregation during mitosis and meiosis
Keywords: بازرسی مونتاژ اسپیندل; Mitosis; Meiosis; Aneuploidy; Non-disjunction; Spindle assembly checkpoint
Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1
Keywords: بازرسی مونتاژ اسپیندل; APC, Anaphase promoting complex; MCC, Mitotic checkpoint complexBubR1; Cdc20; Mad2; Bub1; Bub3; HeLa cell; Mitotic checkpoint; Spindle assembly checkpoint; MCC; Mitotic checkpoint complex