Keywords: اسپراگ داولی; CCK-8; cell counting kit-8; DAPI; 4,6-diamidino-2-phenylindole; DMEM; dulbecco's modified Eagle's medium; D-MTJ; decellularized myotendinous junction; ECM; extracellular matrix; EGF; epidermal growth factor; EM; elastic modulus; FBS; fetal bovine seru
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Keywords: اسپراگ داولی; CTA; conditioned taste aversion; CPP; conditioned place preference; MA; methamphetamine; NAcc; nucleus accumbens; hr; hours; mins; minutes; SD; Sprague Dawley; Addiction; Aversion; Reward; Nucleus accumbens; Methamphetamine; Brain; Behavior;
Keywords: اسپراگ داولی; PNI; Rat; Sprague Dawley; Wistar; Fischer; Long Evans; Lewis; SFI; DigiGait; Proprioception; Sensorimotor; Sciatic nerve;
Keywords: اسپراگ داولی; Honokiol microemulsion; Cerebral ischemia protection; Embryo-fetal development toxicity; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; GD; gestation day; GLP; Good Laboratory Practice; ICH; International Conference on Har
Keywords: اسپراگ داولی; FDR; False Discovery Rate; GO; Gene Ontology; SD; Sprague Dawley; CTA; Computed Tomography Angiography; MRA; Magnetic Resonance Angiography; DSA; Digital Subtraction Angiography; lnc-RNA; Long non-coding RNA; CXCL; Chemokine ligang; Atherosclerosis; Trans
Keywords: اسپراگ داولی; CsA; cyclosporine; PLGA; poly(lactide-co-glycolide); nCsA; CsA encapsulated nanoparticles; mCsA; CsA encapsulated microparticles; SD; Sprague Dawley; CPC; eruloplasmin; LDL; low-density lipoprotein; BUN; blood urea nitrogen; PC; plasma creatinine; FBG; fi
Keywords: اسپراگ داولی; GFs; growth factors; ALG; alginate; HA; hyaluronic acid; HEP; heparin; PEI; polyethyleneimine; PHEMA; poly(2-hydroxyethyl methacrylate); PEG; poly(ethylene glycol); PEO; poly(ethylene oxide); DEX; dextran; PPO; poly(propylene oxide); PPG; poly(propylene g
Keywords: اسپراگ داولی; Pelvic plexus; Urine storage; Rats; Sprague Dawley; Urinary bladder
Retina Compatible Interactions and Effective Modulation of Blood Ocular Barrier P-gp Activity by Third-Generation Inhibitors Improve the Ocular Penetration of Loperamide
Keywords: اسپراگ داولی; P-gp inhibitors; electroretinography; elacridar; tariquidar; blood aqueous barrier (BAB); blood retinal barrier (BRB); ABC; adenosine tri-phosphate-binding cassette; AH; aqueous humor; BAB; blood aqueous barrier; BM; Bruch's membrane; BOB; blood ocular
Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
Keywords: اسپراگ داولی; δ-OR; delta-opioid receptor; DPN; diabetic polyneuropathy; ED50; half-effective drug dose; Emax; maximally effective drug dose; HPT; hot plate threshold; κ-OR; kappa opioid receptor; M6S; morphine-6-O-sulfate; MPE; maximum possible effect; μ-OR; mu-opi
A dabigatran etexilate phospholipid complex nanoemulsion system for further oral bioavailability by reducing drug-leakage in the gastrointestinal tract
Keywords: اسپراگ داولی; Dabigatran etexillate; Nanoemulsions; Phospholipid complex; pH-dependent solubility; Bioavailability; DE; dabigatran etexilate; DE-PC; dabigatran etexilate-phospholipid complex; SGIF; simulated gastrointestinal fluids; GI; gastrointestinal; SGF; simulated
Euphorbia kansui fry-baked with vinegar modulates gut microbiota and reduces intestinal toxicity in rats
Keywords: اسپراگ داولی; EK; Euphorbia kansui; VEK; EK fry-baked with vinegar; TCM; traditional Chinese medicine; SD; Sprague Dawley; TIC; total ion-current; RT; retention time; ALT; alanine aminotransferase; AST; aspartate aminotransferase; SOD; superoxide dismutase; GSH; glutat
Pleiotropic neuropathological and biochemical alterations associated with Myo5a mutation in a rat Model
Keywords: اسپراگ داولی; α-Syn-P; α-synuclein phosphorylated; Tau-P; tau phosphorylated; mutant; homozygous mutant BD-IV rats; BD-IV; Berlin Druckrey; SD; Sprague Dawley; Myo5a; Myosin5a gene; DA; dopamine; DOPAL; 3,4-dyhydroxyphenyl-acetaldehyde; DOPAC; dihydroxyphenylacetic a
NMDA receptors inhibit axonal outgrowth by inactivating Akt and activating GSK-3β via calcineurin in cultured immature hippocampal neurons
Keywords: اسپراگ داولی; NMDA; N-methyl-D-aspartate; APV; DL-2-amino-5-phosphonovalerate; SD; Sprague Dawley; CsA; Cyclosporine; PFA; paraformaldehyde; RT-PCR; reverse transcription PCR; GSK-3; Glycogen synthase kinase-3; T/D-CRMP-2; collapsin response mediator protein 2; OKA; ok
Network pharmacology study reveals energy metabolism and apoptosis pathways-mediated cardioprotective effects of Shenqi Fuzheng
Keywords: اسپراگ داولی; SQ; Shenqi Fuzheng; I/R; Ischemia-reperfusion; TCM; traditional Chinese medicine; NTRA; Network topology and Transcriptomics based Approach; NRIODN; Network Recovery Index for Organism Disturbed Network; MOA; Mechanism of action; HPLC; High performance li
aPKC-Mediated Persistent Increase in AMPA/NMDA Ratio in the VTA Participates in the Neuroadaptive Signal Necessary to Induce NAc Synaptic Plasticity After Cocaine Administration
Keywords: اسپراگ داولی; VTA plasticity; NAc plasticity; PKM-ζ; ZIP; Sprague Dawley;
Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1
Keywords: اسپراگ داولی; Angiotensin II; Vascular smooth muscle cell (VSMC); Sphingosine-1-phosphate receptor (S1PR); APE/Ref-1; Vascular neointima; DCF-DA; 6-carboxy-2â²,7â²-dichlorofluoroscein diacetate; Ang II; angiotensin II; AT; Ang II receptor; APE/Ref-1; apurinic/apyrimi
Evidence-based adverse outcome pathway approach for the identification of BPA as en endocrine disruptor in relation to its effect on the estrous cycle
Keywords: اسپراگ داولی; Bisphenol A; Endocrine disruption; Female reproduction; Estrogen; â; increase; â; decrease; 2G; 2-generation study; 3G; 3-generation study; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail, (French Ag
ANGPTL-4 induces diabetic retinal inflammation by activating Profilin-1
Keywords: اسپراگ داولی; Diabetic retinopathy (DR); Angiopoietin-like protein-4 (ANGPTL-4); Profilin-1; Hypoxia inducible factor-1 alpha (HIF-1α); Inflammation; Adipocytokine; T2DM; type 2 diabetes mellitus; DR; diabetic retinopathy; PDR; proliferative diabetic retinopathy; HG;
Critical role for Annexin A7 in secondary brain injury mediated by its phosphorylation after experimental intracerebral hemorrhage in rats
Keywords: اسپراگ داولی; ANXA7; Annexin A7; FJB; fluoro-jade B; ICH; intracerebral hemorrhage; NMDA receptor; N-methyl-d-aspartate receptor; PSD95; postsynaptic density protein 95; SBI; secondary brain injury; SD; Sprague Dawley; SNAP23; Synaptosome associated protein 23; SNAP25;
Divergent brain changes in two audiogenic rat strains: A voxel-based morphometry and diffusion tensor imaging comparison of the genetically epilepsy prone rat (GEPR-3) and the Wistar Audiogenic Rat (WAR)
Keywords: اسپراگ داولی; SD; Sprague Dawley; GEPR-3; Genetically Epilepsy Prone Rat 3; WIS; Wistar; WAR; Wistar Audiogenic Rat; VBM; Voxel based morphometry; DTI; diffusion tensor imaging; FA; fractional anisotropy; SC; superior colliculus; IC; inferior colliculus; AGS; audiogeni
Comprehensive characterization of in vitro and in vivo metabolites of 2â²,3â²,5â²âtriâOâacetylâN6â(3âhydroxyphenyl) adenosine and study of the metabolites distribution in rats by combined methods of HPLC-DAD, off-line cryoNMR, and HPLC-QTOF
Keywords: اسپراگ داولی; RLMs; rat liver microsomes; HPLC-DAD; high-performance liquid chromatography coupled to a diode array detector; cryoNMR; cryogenically cooled probe nuclear magnetic resonance; UPLC-QTOFMS; ultra-performance LC-quadrupole TOF MS; AMPK; AMP-activated protei
Simultaneous determination of ten bioactive constituents of Sanjie Zhentong Capsule in rat plasma by ultra-high-performance liquid chromatography tandem mass spectrometry and its application to a pharmacokinetic study
Keywords: اسپراگ داولی; IS; internal standard; MRM; multiple reaction monitoring mode; SD; Sprague Dawley; SIM; selected ion monitoring; SZC; Sanjie Zhentong Capsule; TCMP; traditional Chinese medicine prescription; LC-MS; MS; Non-compartment model; Pharmacokinetics; Sanjie zh
Chiral resolution of serial potent and selective Ï1 ligands and biological evaluation of (â)-[18F]TZ3108 in rodent and the nonhuman primate brain
Keywords: اسپراگ داولی; calcd; calculated; CH2Cl2; dichloromethane; CNS; central nervous system; DMSO; dimethyl sulfoxide; [3H]DTG; [3H]ditolylguanidine; DTTA; di-p-toluoyl tartaric acid; EBP; emopamil binding protein; ee; enantiomeric excess; EOB; end of bombardment; EtOH; etha
Research PaperRaphe gene expression changes implicate immune-related functions in ventilatory plasticity following carotid body denervation in rats
Keywords: اسپراگ داولی; CBD; carotid body denervation; SD; Sprague Dawley; VE; minute ventilation; VT; tidal volume; 5-HT; serotonin; Respiratory plasticity; Carotid body denervation (CBD); Medullary raphe; Neural control of breathing; Serotonin; RNA Sequencing; Neuro-immune res
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway
Keywords: اسپراگ داولی; BCA; bicinchoninic acid; bFGF; basic fibroblast growth factor; BSA; bovine serum albumin; caspase; cysteine-aspartic acid protease; DCFH-DA; 2â², 7â²-dichloroflurescin- diacetate; DMEM; dulbecco's modified eagle medium; ECM; extracellular matrix; E. col
The lateral habenula and alcohol: Role of glutamate and M-type potassium channels
Keywords: اسپراگ داولی; AUD; alcohol use disorder; BK; big potassium; BNST; bed nucleus of the stria terminalis; CAMKII; calcium/calmodulin dependent kinase II; CeA; Central Amygdala; CTA; conditioned taste aversion; DA; dopaminergic; DAR; dopamine receptors; D1R; dopamine recep
Effects of testosterone on mean arterial pressure and aquaporin (AQP)-1, 2, 3, 4, 6 and 7 expressions in the kidney of orchidectomized, adult male Sprague-Dawley rats
Keywords: اسپراگ داولی; Testosterone; Blood pressure; Aquaporins; Kidneys; AQP; aquaporin; CD; collecting duct; cDNA; complementary deoxyribonucleic acid; DBP; diastolic blood pressure; DCT; distal convoluted tubule; DHT; dihydrotestosterone; G; glomerulus; H2O; water; HRP; hors
Acute and sub-acute toxicological evaluation of lyophilized Nymphaea x rubra Roxb. ex Andrews rhizome extract
Keywords: اسپراگ داولی; N. rubra; Extraction; Lyophillization; RP-HPLC analysis; Acute and sub-acute toxicity study; Hippocratic screening; Hematology; N. rubra; Nymphaea x rubra Roxb. ex Andrews; RBC; Red Blood Cells; RP-HPLC; Reverse Phase High Performance Liquid Chromatogra
Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation
Keywords: اسپراگ داولی; 4-MDM; 4-methoxydiphenylmethane; ACN; acetonitrile; APPI; atmospheric pressure photoionization; BCS; biopharmaceutical classification system; CAD; collision activated dissociation; CE; collision energy; COPD; chronic obstructive pulmonary disease; CEP; co
Anti-TNF-α and anti-arthritic effect of patuletin: A rare flavonoid from Tagetes patula
Keywords: اسپراگ داولی; RA; rheumatoid arthritis; TNF; tumor necrosis factor; NO; nitric oxide; IL; interleukin; ROS; reactive oxygen species; AIA; adjuvant induced arthritis; MMP; matrix metalloproteinase; PMNs; polymorphonuclear cells; PO; peroxide; RF; rheumatoid factor; SD;
Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-β activated kinase-1 binding protein-1 signaling pathway
Keywords: اسپراگ داولی; COX-2; cyclooxygenase-2; DAPI; 4,6-diamino-2-phenyl indole; DHA; docosahexaenoic acid; EBI; early brain injury; EMSA; electrophoretic mobility shift assays; EPA; eicosapentaenoic acid; FJB; Fluoro-Jade B; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G
Fluorocitrate induced the alterations of memory-related proteins and tau hyperphosphorylation in SD rats
Keywords: اسپراگ داولی; FC; fluorocitrate; GSK-3β; glycogen synthase kinase-3β; pS9; phosphorylated GSK-3β at serine 9; PP2A; protein phosphatase-2A; PP2AC; PP2A catalytic subunit; pY307; phosphorylated PP2A catalytic subunit at tyrosine-307; CREB; cAMP response element bindi
Telmisartan mediates anti-inflammatory and not cognitive function through PPAR-γ agonism via SARM and MyD88 signaling
Keywords: اسپراگ داولی; AP-1; activator protein-1; ANOVA; analysis of variance; AT1; angiotensin II receptor 1; BBB; blood brain barrier; C; control; CaCl2; calcium chloride; CMC; carboxy methyl cellulose; CSF; cerebrospinal fluid; JNK/c-Jun; c-Jun N-terminal kinases; COX-2; cyc
Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatum
Keywords: اسپراگ داولی; Basal ganglia; Schizophrenia; Parkinson's disease; Huntington's disease; ANOVA; Analysis of Variance; BAC; bacterial artificial chromosome; c-Fos(+); c-Fos immunopositive nuclei; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate;
Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats
Keywords: اسپراگ داولی; AD; Alzheimer's disease; Aβ; amyloid β; ANOVA; analysis of variance; BBB; blood-brain barrier; DPPIV; DPPIV dipeptidyl peptidase IV; fEPSPs; Field excitatory postsynaptic potentials; GLP-1; glucagon-like peptide-1; GLP-1R; GLP-1 receptor; GSK3β; gl
Acute and sub-chronic toxicity studies of the extract of Thunberg Fritillary Bulb
Keywords: اسپراگ داولی; ALB; albumin; ALT; alanine aminotransferase; ALP; alkaline phosphatase; AST; aspartate aminotransferase; APTT; activated partial thromboplastin time; BW; body weight; BUN; urea nitrogen; CK; creatine kinase; CMC; carboxyl methyl cellulose; CNS; central ne
Toxicologic assessment of Paecilomyces tenuipes in rats: Renal toxicity and mutagenic potential
Keywords: اسپراگ داولی; SD; Sprague Dawley; OECD; Organization for Economic Co-operation and Development; WBC; white blood cell; RBC; red blood cell; HGB; hemoglobin; HCT; hematocrit; PLT; platelet; MCV; mean corpuscular volume; MCH; mean corpuscular hemoglobin; MCHC; mean corpu
mTOR pathway is involved in ADP-evoked astrocyte activation and ATP release in the spinal dorsal horn in a rat neuropathic pain model
Keywords: اسپراگ داولی; AMPK; AMP-activated protein kinase; CCI; chronic constriction injury model; CSF; cerebrospinal fluid; GFAP; glial fibrillary acidic protein; mTOR; mammalian target of rapamycin; SD; Sprague Dawley; vFh; Von Frey hairs; adenosine triphosphate; adenosine di
A comparative study of the bone metabolic response to dried plum supplementation and PTH treatment in adult, osteopenic ovariectomized rat
Keywords: اسپراگ داولی; AIN; American Institute of Nutrition; Alp; alkaline phosphatase; BAP; bone-specific alkaline phosphatase; BFR; bone formation rate; BMD; bone mineral density; BMP; bone morphogenetic protein; BV/TV; bone volume per total volume; Conn Density; connectivity
Isolation and cultivation of metabolically competent alveolar epithelial cells from A/J mice
Keywords: اسپراگ داولی; AECs; alveolar epithelial cells; AP; alkaline phosphatase; B[a]P; benzo[a]pyrene; CYP; cytochrome P; DMEM; Dulbecco's modified Eagle Medium; EROD; ethoxyresorufin-O-deethylase; FCS; Fetal Calf Serum; FITC; fluorescein isothiocyanate; FMO; flavine monoox
Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells
Keywords: اسپراگ داولی; AMPK; AMP-activated protein kinase; CHOP; C/EBP homologous protein; CPT-1; Carnitine palmitate transferase-1; DAG; diacylglycerol; ER; endoplasmic reticulum; Eto; etomoxir; FAO; fatty acid oxidation; HG/PA; high glucose/palmitate; JNK; C-Jun N-terminal ki
Waxholm Space atlas of the Sprague Dawley rat brain
Keywords: اسپراگ داولی; Digital brain atlas; Waxholm Space; Sprague Dawley; Rat brain template; Segmentation; Magnetic resonance imaging; Diffusion tensor imaging; Neuroinformatics;
Research reportActivation of extracellular signal-regulated kinase (ERK) and ÎFosB in emotion-associated neural circuitry after asymptotic levels of active avoidance behavior are attained
Keywords: اسپراگ داولی; Wistar Kyoto; Sprague Dawley; Anxiety; Prefrontal cortex; Dorsal striatum; Amygdala;
Anti-diabetic activities of Gegen Qinlian Decoction in high-fat diet combined with streptozotocin-induced diabetic rats and in 3T3-L1 adipocytes
Keywords: اسپراگ داولی; DM; diabetes mellitus; GGQLD; Gegen Qinlian Decoction; GGQLD-CS; Gegen Qinlian Decoction-containing serum; TCM; traditional Chinese medicine; TG; triglyceride; HFD; high-fat diet; STZ; streptozotocin; SD; Sprague Dawley; HbA1c; glycosylated hemoglobin; DM
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway
Keywords: اسپراگ داولی; AGE; Advanced glycation end product; AP-1; Activator protein 1; BUN; Blood urea nitrogen; Cr; Serum creatinine; Cur; Curcumin; DN; Diabetic nephropathy; ECM; Extracellular matrix; FBG; Fasting blood glucose; FN; Fibronectin; GBM; Glomerular basement membr
Radio-decontamination efficacy and safety studies on optimized decontamination lotion formulation
Keywords: اسپراگ داولی; Decontamination; Technetium-99m; Iodine-131; Thallium-201; Sprague Dawley; Human tissue equivalent;
The effect of thermopreference on circadian thermoregulation in sprague-dawley and fisher 344 rats
Keywords: اسپراگ داولی; Behavioral thermoregulation; Core temperature; Selected ambient temperature; Circadian temperature; Sprague Dawley; Fisher 344;
Assessing learned associations between conditioned cocaine reward and environmental stimuli in the Wistar Kyoto rat
Keywords: اسپراگ داولی; Wistar Kyoto; Cocaine; Conditioned place preference; Extinction; Reinstatement; Sprague Dawley
Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABAA-benzodiazepine receptors
Keywords: اسپراگ داولی; BBB; blood-brain barrier, BZD, benzodiazepine; c.c.; column chromatography; CHCl3; chloroform; CMC; carboxymethyl cellulose; CNS; Central nervous system; CON; control group; DPM; disintegrations per minute; DW; distilled water; DZP; diazepam; EtOAc; ethyl