Phospho-GSK-3β is involved in the high-glucose-mediated lipid deposition in renal tubular cells in diabetes
Keywords: Bad; GSK-3β; PI3K/Akt pathway; SREBP-1; Lipid metabolism;
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Effect of different dietary fats on protein expression of sterol regulatory element-binding protein 1 (SREBP-1) in mammary gland tissue of lactating cows
Keywords: CEBPs; CCAAT/enhancer-binding proteins; CLA; conjugated linoleic acid; DM; dry matter; FA; fatty acids; FAS; fatty acid synthase; LINA; linseed oil/DHA rich algae supplemented group; LSM; least squares mean; pSREBP-1; SREBP-1 precursor; mSREBP-1; mature S
Lipid metabolism in mammalian tissues and its control by retinoic acid
Keywords: ACC; acetyl-coA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; atRA; all-trans retinoic acid; BAT; brown adipose tissue; BCMO1; β,β-carotene monooxygenase 1; C/EBP; CCAAT-enhancer binding protein; CAC; carnitine/acylcarnitine c
Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis
Keywords: 7α-OH; 7α-hydroxycholesterol; 7-K; 7-ketocholesterol; 9-ONC; 9-oxononanoyl cholesterol; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; α-EPOX; 5α,6α-epoxycholesterol; AP-1; activator protein-1; ARE; antioxidant-responsive element; ATF; activating trans
Silk protein hydrolysate increases glucose uptake through up-regulation of GLUT 4 and reduces the expression of leptin in 3T3-L1 fibroblast
Keywords: 2-DG; 2-deoxy-d-[1,2-3H] glucose; DMEM; Dulbecco's modified Eagle's medium; FAS; fatty acid synthase; FBS; fetal bovine serum; GLUT; glucose transporter; IBMX; isobutylmethylxanthine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PG;
Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose
Keywords: HNF4; IRS-2; Fatty acid oxidation; SREBP-1
PTEN ameliorates high glucose-induced lipid deposits through regulating SREBP-1/FASN/ACC pathway in renal proximal tubular cells
Keywords: PTEN; SREBP-1; High glucose; Lipogenesis; Renal proximal tubular cells; TGF-β1
High density lipoprotein inhibits the activation of sterol regulatory element-binding protein-1 in cultured cells
Keywords: HDL(-c); high density lipoprotein (-cholesterol); RCT; reverse cholesterol transport; NAFLD; non-alcoholic fatty liver disease; SRBI; scavenger receptor class BI; SREBP-1; sterol regulatory element-binding protein-1; nSREBP-1 or pSREBP-1; nuclear form or
The gene expression of the myocardial lipid droplet protein is highly regulated by PPARγ in adipocytes differentiated from MEFs or SVCs
Keywords: MEF; SVC; MLDP; Adipocyte; SREBP-1; PPARγ;
Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway
Keywords: Akt; Curcumin; HCV; NS5A; SREBP-1
Cide-a and Cide-c are induced in the progression of hepatic steatosis and inhibited by eicosapentaenoic acid
Keywords: Cide-a; Cide-c; SREBP-1; EPA; Steatosis
Effect of Chinese prescription Kangen-karyu on lipid metabolism in type 2 diabetic db/db mice
Keywords: Type 2 diabetes; db/db mice; Kangen-karyu; SREBP-1; Hyperlipidemia
Dietary polyunsaturated fatty acids slow the progression of diabetic nephropathy in streptozotocin-induced diabetic rats
Keywords: Alb; albumin; DML; diabetic rats fed a lard diet containing saturated fatty acids; DMR; diabetic rats fed 1a rapeseed oil diet containing polyunsaturated fatty acid; FA; fatty acid; FFA; free fatty acid; Glc; glucose; NL; nontreated rats fed a lard diet;
A Mutant of Hepatitis B Virus X Protein (HBxÎ127) Promotes Cell Growth through A Positive Feedback Loop Involving 5-Lipoxygenase and Fatty Acid Synthase
Keywords: 5-LOX; 5-lipoxygenase; COX; cyclooxygenase; FAS; fatty acid synthase; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; Indo; indomethacin; LTB4; leukotriene B4; p-ERK1/2; phosphorylated extracellular signal-regulated protein kinases 1/2; S
Transcriptional regulation of 17β-hydroxysteroid dehydrogenase type 12 by SREBP-1
Keywords: Fatty acid; SREBP-1; 17β-Hydroxysteroid dehydrogenase type 12
Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice
Keywords: Pten KO; Pten-deficient; EPA; eicosapentaenoic acid; ROS; reactive oxygen species; HCC; hepatocellular carcinoma; NASH; non-alcoholic steatohepatitis; NAFLD; non-alcoholic fatty liver disease; TG; triglyceride; PUFA; polyunsaturated fatty acid; SREBP-1; s
Transport of fatty acids across the human placenta: A review
Keywords: Placenta; Fatty acids; Plasma membrane fatty acid-binding proteins; Fatty acid transporter protein; Fatty acid translocase; Long chain polyunsaturated fatty acids; Fetus; Brain; Trophoblast; Human placenta; EFA; Nuclear transcription factors; ACSBG; acylC
Identification of cis-acting promoter sequences required for expression of the glycerol-3-phosphate acyltransferase 1 gene in mice
Keywords: GPAT1; glycerol-3-phosphate acyltransferase 1; USF-1; upstream stimulatory factor-1; SREBP-1; sterol regulatory element-binding protein-1; ORF; open reading frame; 5â²-RACE; 5â²-Rapid amplification of cDNA ends; siRNA; small interfering RNA; EMSA; Elect
Regulation of hepatic PPARγ2 and lipogenic gene expression by melanocortin
Keywords: Fatty liver; Obesity; Melanocortin; Lipogenesis; PPARγ; SREBP-1
Adipogenesis of bovine perimuscular preadipocytes
Keywords: Adipocyte; Bovine; Differentiation; Fat development; Gene expression; PPAR-γ; SREBP-1; Transcription factor;
Sp1: Emerging roles-Beyond constitutive activation of TATA-less housekeeping genes
Keywords: Sp1; Transcription factor; TAF4; Mediator; Synergism; SREBP-1; p53; Smad; Cell proliferation; Tumorigenesis;
Olanzapine induces SREBP-1-related adipogenesis in 3T3-L1 cells
Keywords: Olanzapine; Adipogenesis; 3T3-L1; SREBP-1; Fatty acid synthase
Isomer specific effects of Conjugated Linoleic Acid on macrophage ABCG1 transcription by a SREBP-1c dependent mechanism
Keywords: Conjugated Linoleic Acid; Macrophages; Microarrays; SREBP-1; SREBP-1c; ABCG1CLA, Conjugated Linoleic Acid; c9,t11, cis-9,trans-11; FC, fold change; LXR, liver X receptor; MCSF, macrophage colony stimulating factor; nSREBP, nuclear SREBP; PMA, phorbol 12-m
Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling
Keywords: Fatty acid synthase; Theanaphthoquinone; SREBP-1; EGFR; ErbB-2
Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders
Keywords: Diabetes; Kidney; Lipotoxicity; Lipogenesis; Obesity; SREBP-1
LDL receptor gene transcription is selectively induced by t10c12-CLA but not by c9t11-CLA in the human hepatoma cell line HepG2
Keywords: CLA, conjugated linoleic acid; LA, linoleic acid; SREBP, sterol regulatory element binding protein; HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductaseConjugated linoleic acid; LDL receptor; Atherosclerosis; SREBP-2; SREBP-1
Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP
Keywords: SREBP-1; Insulin; cAMP; Hepatocyte; Insig; Ubiquitin;
A novel SREBP-1 splice variant: Tissue abundance and transactivation potency
Keywords: SREBP; sterol regulatory element binding protein; LDLR; low density lipoprotein receptor; bHLH-LZ; basic helix-loop-helix-leucine zipper; UCP2; uncoupling protein 2; SREBP-1; Alternative splicing; Transcriptional regulation;
Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line
Keywords: LXR; Placenta; Lipid synthesis; hCG; SREBP-1; BeWo cells;