Effect of different dietary fats on protein expression of sterol regulatory element-binding protein 1 (SREBP-1) in mammary gland tissue of lactating cows

Upon a ten-week feeding intervention, significantly reduced milk fat contents, total saturated fatty acid amounts and single saturated fatty acid concentrations (C10:0, C12:0, C14:0, C16:0) were obtained in LINA and SUNA group, whereas milk yields did not substantially differ between feeding groups. The assumption that the effects of plant oil/DHA rich algae supplementation on milk fat composition were mediated by shifted SREBP-1 protein expression were only confirmed in regard to slightly reduced protein expression levels of pSREBP-1 in SUNA group tissue samples (P = 0.087), whereas similar protein expression levels of transcriptionally active mSREBP-1 were found in SAT, LINA and SUNA group.