Keywords: Obesity; Polyphenol; Adipogenesis; PPARγ; Lipid; Rice; ABTS; 2,2â²-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid; ACO; acyl-CoA oxidase; CYP4A10; cytochrome P450; AMPK; AMP-activated protein kinase; AT; adipose tissue; C/EBPâ; CAAT/enhancer-bindin
مقالات ISI (ترجمه نشده)
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Keywords: ACACA; acetyl-coenzyme A carboxylase α; ADF; acid detergent fibre; ADG; average daily gain; BCVFA; branched chain volatile fatty acids; BHBA; beta-hydroxybutyrate; BW; body weight; CP; crude protein; DM; dry matter; CPT1; carnitine palmitoyl transferase-
Keywords: AHR; aryl hydrocarbon receptor; ALD; alcoholic liver disease; BAs; bile acids; CAR; constitutive androstane receptor; CARM1; coactivator associated arginine methyltransferases 1; CBP/P300; CREB-binding protein/p300; CYP27A1/Cyp27a1; sterol 27α-hydroxylas
Keywords: Butein (PubChem CID: 5281222); Cardamonin (PubChem CID: 641785); 2â²,4â²-Dihydroxy-6â²-methoxy-3â²,5â²-dimethylchalcone (PubChem CID: 10424762); Flavokawain B (PubChem CID: 5356121); Hydroxysafflor Yellow A (PubChem CID: 6443665); Naringenin Chalcone
Keywords: Brimonidine; Phospholipidosis; α2 adrenergic agonist; α2 adrenergic antagonist; Meibomian gland dysfunction; Dry eye disease; phosphoinositide 3-kinase-protein kinase B; AKT; bovine pituitary extract; BPE; cationic amphiphilic drug; CAD; adenosine 3,5-c
Keywords: ACC; acetyl-CoA carboxylase; ACE; angiotensin-converting enzyme; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ALDH2; aldehyde dehydrogenase 2; AMPK; 5' AMP-activated protein kinase; ATP; adenosine triphosphate; Bax; Bcl-2-like protein 4; BNIP3; B
Keywords: NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; SREBP-1; sterol regulatory element-binding protein-1; TG; triglyceride; TC; total cholesterol; ipGTT; intraperitoneal glucose tolerance test; IRS; insulin receptor substrate; Non-alcoholic fatt
Keywords: Type 1 diabetes; Gluconeogenesis; Glucokinase; Biotin; FOXO1; SREBP-1;
Keywords: ACADM; medium chain acyl-CoA dehydrogenase; ACADVL; very long chain acyl-CoA dehydrogenase; ACC; acetyl-coenzyme A carboxylase alpha; ACSL1; acyl-CoA synthetase long-chain family member 1; ADIPOR2; adiponectin receptor 2; Akt; protein kinase B; AK2; Adeny
Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: AMPK; AMP-activated protein kinase; Angptl-4; Angiopoietin-like protein 4; D55; Inject animals with 55Â mg/kg through tail vein; D100; Inject animals with 100Â mg/kg through tail vein; EC; Endothelial cell; ECCM; Endothelial cell conditioned medium; ER; E
Keywords: Omega-6:omega-3; Nonalcoholic fatty-liver disease; High-fat diet; α-Linolenic acid; Colitis; Murine model; 4-HNE; 4-hydroxy-2-nonenal; AA; arachidonic acid; ALA; alpha-linolenic acid; ATF6; activating transcription factor 6; BiP; binding immunoglobulin p
Keywords: AA; arachidonic acid; ALP; alkaline phosphatase; ALX; G protein-coupled lipoxin A(4) receptor; AMP; adenosine monophosphate; BAT; brown adipose tissue; BMC; bone mineral content; BMD; bone mineral density; BMI; body mass index; CKD; chronic kidney disease
Keywords: FADS2; SCD; SREBP-1; Desaturase; Dry-cured ham;
β3-adrenergic receptor activation induces TGFβ1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway
Keywords: β3-adrenergic receptor; Transforming growth factor β1; Protein kinase G; c-Jun N-Terminal kinase; c-Jun; Cardiomyocyte; AP-1; activator protein 1; β-AR; β-adrenergic receptor; cGMP; cyclic guanosine monophosphate; GRK; G protein-coupled receptor kinas
Fluvastatin activates sirtuin 6 to regulate sterol regulatory element-binding proteins and AMP-activated protein kinase in HepG2 cells
Keywords: SIRT6; Fluvastatin; SREBP-1; AMP-Activated protein kinaseα; Nonalcoholic fatty liver disease;
An important role of SREBP-1 in HBV and HCV co-replication inhibition by PTEN
Keywords: HBV; HCV; Co-replication; PTEN; SREBP-1;
CGplus, a standardized herbal composition ameliorates non-alcoholic steatohepatitis in a tunicamycin-induced mouse model
Keywords: Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Hepatotherapeutic; Herbal medicine; ACADL; acyl-CoA dehydrogenase long chain; AMPK; AMP-activated protein kinase; ANOVA; analysis of variance; ALT; alanine transaminase; AST; aspartate tran
CREB element is essential for unfolded protein response (UPR) mediating the Cu-induced changes of hepatic lipogenic metabolism in Chinese yellow catfish (Pelteobagrus fulvidraco)
Keywords: ACC; Acetyl-CoA carboxylase; CREB; cAMP-response element binding protein; ATF6; Activating transcription factor 6; ER; endoplasmic reticulum; ERSE; ER stress response element; FAS; Fatty acid synthase; GRP78/BiP; 78-kDa glucose-regulated protein; IRE1; In
Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway
Keywords: ASC; apoptosis-associated speck-like protein; CPT-1; carnitine palmitoyl transferase-1; GST; glutathione S-transferase; HO-1; hemeoxygenase-1; H2O2; hydrogen peroxide; IL; interleukin; Keap1; Kelch-like ECH-associated protein 1; MDA; malondialdehyde; miR-
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways
Keywords: Arctigenin; Lipotoxicity; Steatosis; Inflammation; Nonalcoholic fatty liver disease; ACC1; acetylcoenzyme A carboxylase 1; ACO; acyl-CoA oxidase; ATG; arctigenin; CPT-1; carnitine palmitoyltransferase 1; FAS; fatty acid synthase; MDA; malondialdehyde; NAF
DNA methylation signatures at endoplasmic reticulum stress genes are associated with adiposity and insulin resistance
Keywords: Endoplasmic reticulum; Epigenetics; Obesity; Triglycerides; Insulin resistance; BMI; body mass index; CASP12; caspase 12; CpG; cytosine-phosphate-guanine site; DBP; diastolic blood pressure; DiOGenes; diet obesity and genes dietary trial; DNAJC1; dnaJ hea
Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress
Keywords: AA; arachidonic acid; AMPK; AMP-dependent protein kinase; ATGL; adipose triglyceride lipase; cPLA2α; cytosolic group IVA PLA2; CPT1; carnitine O-palmitoyltransferase 1; CPT1A; the liver isoform of CPT1; DGAT1; diacylglycerol acyltransferase 1; DHA; docos
CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes
Keywords: Alcohol liver disease; Ethanol; α-Tocopherol; CYP4F2; PPAR-γ; SREBP-1;
Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion
Keywords: TGF-β1; transforming growth factor beta 1; SREBP-1; sterol regulatory element binding protein-1; TβRI; TGF-β receptor I; Exosome; Transforming growth factor β; Kidney; SREBP-1; TβRI;
Acanthoic acid protectsagainst ethanol-induced liver injury: Possible role of AMPK activation and IRAK4 inhibition
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; TG; triglyceride; IL1α; interleukin-1α; IL-1β; interleukin-1β; IL-6; interleukin-6; IL-18; interleukin-18; TNF-α; tumor necrosis factor-α; SREBP-1; sterol regulatory element binding pro
Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids
Keywords: ACC; acetyl-CoA carboxylase; ATF6; activating transcription factor6; AB-PAS; alcian blue-periodic acidschiff; ACC; acetyl-CoA carboxylase; ACSL; long-chain acyl-CoA synthetase; Bad; Bcl-2-associated death promoter; Bax; Bcl-2-like protein 4; Bcl-2; B-cell
Regulation of growth, antioxidant capacity, fatty acid profiles, hematological characteristics and expression of lipid related genes by different dietary n-3 highly unsaturated fatty acids in juvenile black seabream (Acanthopagrus schlegelii)
Keywords: accα; acetyl-CoA carboxylase alpha; atgl; adipose triglyceride lipase; cpt1a; carnitine palmitoyltransferase 1A; elovl5; elongase 5; fas; fatty acid synthase; g6pd; glucose 6-phosphate dehydrogenase; hsl; hormone-sensitive lipase; lpl; lipoprotein lipase
Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6
Keywords: HCC; Cancer Stem Cells; HuR; Hepatocarcinogenesis; ACTA2; α-smooth muscle actin; Ad; adenovirus; aHSC; activated hepatic stellate cell; AKT; AKT serine/threonine kinase 1; ARE; AU-rich element; BDL; bile duct ligation; BSC; BDL-derived aHSC cell line; CC
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth
Keywords: miR-29; SCAP; SREBP-1; EGFR; lipid metabolism; glioblastoma
Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease
Keywords: Diabetic nephropathy; TXNIP; Lipid accumulation; Akt/mTOR; SREBP-1; PPARα;
A multispecies Lactobacillus- and Bifidobacterium-containing probiotic mixture attenuates body weight gain and insulin resistance after a short-term challenge with a high-fat diet in C57/BL6J mice
Keywords: CLAs; conjugated linoleic acids; CT; control diet; FIAF; fasting-induced adipocyte factor; GLP-1; glucagon-like peptide-1; HF; high-fat diet; HF-Pb; high-fat diet with probiotic mixture; 5-HPETE; 5-hydroperoxyeicosatetraenoic acid; IBS; inflammatory bowel
AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells
Keywords: TNF-α; AMPK; Lipid accumulation; Metformin; SREBP-1; mTOR
Regulation and mechanism of leptin on lipid metabolism in ovarian follicle cells from yellow catfish Pelteobagrus fulvidraco
Keywords: ACC; acetyl-CoA carboxylase; CPT I; carnitine palmitoyl transferase-I; DMSO; dimethyl sulphoxide; FAS; Fatty acid synthase; G6PD; glucose-6-phosphate dehydrogenase; IRS-PI3K; insulin receptor substrate (IRS)-phosphatidylinositol-3-OH-kinase; JAK-STA
Different effects of dietary Zn deficiency and excess on lipid metabolism in yellow catfish Pelteobagrus fulvidraco
Keywords: ACC; acetyl-CoA carboxylase; ATGL; adipose triglyceride lipase; CPT; carnitine palmitoyltransferase; FAS; fatty acid synthase; FI; feed intake; FBW; final mean body weight; G6PD; glucose-6-phosphate dehydrogenase; HSI; hepatosomatic index; HSL; hormone-se
Co-regulation of SREBP-1 and mTOR ameliorates lipid accumulation in kidney of diabetic mice
Keywords: SREBP-1; MTOR; Diabetic mice; Renal tubular cells; Lipid metabolism;
Cloning and characterization of SREBP-1 and PPAR-α in Japanese seabass Lateolabrax japonicus, and their gene expressions in response to different dietary fatty acid profiles
Keywords: Japanese seabass; SREBP-1; PPAR-α; Gene expression; Dietary fatty acids;
Inhibitory effect of anthocyanin-rich black soybean testa (Glycine max (L.) Merr.) on the inflammation-induced adipogenesis in a DIO mouse model
Keywords: ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPKα; 5Ⲡadenosine monophosphate-activated protein kinase alpha; ANOVA; analysis of variance; AST; aspartate aminotransferase; ATGL; adipose triacylglycerol lipase; BBC; ethanol extracts of b
Stable SREBP-1a knockdown decreases the cell proliferation rate in human preadipocyte cells without inducing senescence
Keywords: CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2B; cyclin-dependent kinase inhibitor 2B; CDKN3; cyclin-dependent kinase inhibitor 3; H3K9me3; histone H3 lysine 9 trimethylation; MTT; 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide; RRBP8;
Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway
Keywords: ACC; acetyl-CoA carboxylase; ALA; alpha-lipoic acid; ALT; alanine aminotransferase; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMPK; AMP-activated protein kinase; AST; aspartate aminostransferase; ATGL; adipose triacylglycerol lipase; CaMKK; Ca2+/cal
Accumulation of lipids and oxidatively damaged DNA in hepatocytes exposed to particles
Keywords: ABCG5; ATP-binding cassette, sub-family G (WHITE), member 5; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; CB; carbon black; DEP; diesel exhaust particles; FASN; fatty acid synthase; FFA; free fatty acids; FPG; formamidopyrimidine DNA glyco
Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21
Keywords: Liver-Specific Disruption of Sirt1; Hepatocyte-Derived Hormone; Metabolic Homeostasis; Obesity; Ad; adenovirus; BAT; brown adipose tissue; CPT1α; carnitine palmitoyltransferase 1α; FAS; fatty acid synthase; FGF21; fibroblast growth factor 21; MCAD; medi
Identification and functional characterization of novel MATE1 genetic variations in Koreans
Keywords: MATE1; Haplotype; Promoter; Nkx-2.5; SREBP-1; USF-1;
Fisetin regulates obesity by targeting mTORC1 signaling
Keywords: mTORC1; mammalian target of rapamycin complex 1; S6K1; 70-kDa ribosomal protein S6 kinase 1; TSC2; tuberous sclerosis protein 2; HFD; high-fat diet; PPAR-γ; peroxisome proliferator-activated receptor γ; SREBP-1; sterol regulatory element-binding protein
Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells
Keywords: AKT; protein kinase B; FAS; fatty acid synthase; HER2; human epidermal growth factor receptor 2; MAPKs; mitogen-activated protein kinases; MMP-2/-9; matrix metalloproteinase (MMP)-2/-9; EGF; epidermal growth factor; PARP; poly-ADPribose polymerase; SREBP-
Lipopolysaccharide downregulates CD91/low-density lipoprotein receptor-related protein 1 expression through SREBP-1 overexpression in human macrophages
Keywords: Lipopolysaccharide; Aggregated LDL; Human macrophages; LRP1; LDLR; SREBP-1; SREBP-2;
3,5-Diiodo-l-thyronine induces SREBP-1 proteolytic cleavage block and apoptosis in human hepatoma (Hepg2) cells
Keywords: DAPI; 4,6-diamidino-2-phenylindole; ERK; extracellular signal-regulated kinase; FASN; fatty acid synthase; FL; firefly luciferase; IRES; internal ribosome entry site; mTOR-C1; mammalian target of rapamycin complex 1; MAPK; mitogen activated protein kinase
Phospho-mTOR: A novel target in regulation of renal lipid metabolism abnormality of diabetes
Keywords: mTOR; SREBP-1; Lipogenesis; Diabetic nephropathy; Akt;
Cholesterol suppresses adipocytic differentiation of mouse adipose-derived stromal cells via PPARγ2 signaling
Keywords: Cholesterol; Mouse adipose-derived stromal cells (mASCs); Adipocytic differentiation; SREBP-1; PPARγ2