Keywords: AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Arc; activity-regulated cytoskeletal-association protein; BDNF; bone-derived neurotrophic factor; CaMK; Ca2+/calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate;
مقالات ISI (ترجمه نشده)
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Keywords: Meiosis; Phosphorylation; Sumoylation; Ginkgolic acid; AURKs; PLK1; GA; ginkgolic acid; OA; okadaic acid; SUMO; Small Ubiquitin-like Modifiers;
Keywords: Nuclear thymidylate synthesis; Antifolate; Folate-mediated one-carbon metabolism; Sumoylation; Thymidylate synthase;
Keywords: Therapeutic hypothermia; Neuroprotection; Ischemia and reperfusion injury; Sumoylation; Unfolded protein response; Cold shock proteins;
Keywords: Intervertebral disc; Hypoxia; Sumoylation; Posttranslational modulation;
Keywords: Phosphorylation; Ubiquitination; SUMOylation; Post-translational modifications; DNA replication; Replisome;
Keywords: Progesterone receptor; Post-translational modification; SUMOylation; Phosphorylation; Transcriptional activity; Breast cancer;
Keywords: Progesterone receptor (PR); Phosphorylation; SUMOylation; Gene expression; Estrogen receptor (ER); AntiprogestinsAF, activation function; AP-1, activator protein 1; CD, common docking; CDK2, cyclin dependent kinase 2; CK2, casein kinase II; DUSP6/MKP3, du
Keywords: ARE; antioxidant response element; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; co-IP; coimmunoprecipitation; GCL; glutamate-cysteine ligase; Gclc; GCL catalytic subunit; Gclm; GCL modifier subunit; GSH; reduced glutathione; GS; GSH s
Keywords: GRIP1; glucocorticoid receptor-interacting protein 1; TIF2; translation initiation factor 2; SRC; steroid receptor coactivator; NR; nuclear receptor; AD; activation domain; CBP; CREB binding protein; APL; acute promyelocytic leukemia; RAR; retinoic acid r
9-cis-retinoic acid elevates MRP3 expression by inhibiting sumoylation of RXRα to alleviate cholestatic liver injury
Keywords: Cholestasis; Multidrug resistance-associated protein 3; Retinoid X receptor; Sumoylation;
SUMO1/sentrin/SMT3 specific peptidase 2 modulates target molecules and its corresponding functions
Keywords: SUMOylation; SENP2; Isopeptidase; De-SUMOylation;
A compendium of adenovirus genetic modifications for enhanced replication, oncolysis, and tumor immunosurveillance in cancer therapy
Keywords: Ad; adenovirus; ADP; adenovirus death protein; CAR; coxsackievirus and adenovirus receptor; KIR; killer inhibitory receptor; MHCI/HLA; major histocompatibility complex class I; MICA/MICB; MHC-I chain-related A and B proteins; MLP; major late promoter; MTT
Sumoylation of SMAD 4 ameliorates the oxidative stress-induced apoptosis in osteoblasts
Keywords: Apoptosis; Osteoblasts; Oxidative stress; SMAD4; SUMOylation;
Talin is a substrate for SUMOylation in migrating cancer cells
Keywords: Talin; SUMOylation; Focal adhesions; Cancer cell migration;
Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells
Keywords: Resveratrol; Inducible COX-2; Sumoylation; p53 and anti-proliferation;
The functional roles of PML nuclear bodies in genome maintenance
Keywords: PML-NB; promyelocytic leukemia nuclear body; DSBs; DNA double-strand breaks; HR; homologous recombination; APL; acute promyelocytic leukemia; ALT; alternative lengthening of telomere; APB; ALT-associated PML bodies; PML nuclear body; SUMOylation; DNA repa
Phosphorylation and SUMOylation of CRMP2 regulate the formation and maturation of dendritic spines
Keywords: CRMP2; Dendritic spine; Phosphorylation; SUMOylation; Neuron;
Toxoplasma ubiquitin-like protease 1, a key enzyme in sumoylation and desumoylation pathways, is under the control of non-coding RNAs
Keywords: Toxoplasma; Sumoylation; Ubiquitin-like protease 1; Regulatory RNA; Non-coding RNA; miRNA; Natural antisense transcript;
Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice
Keywords: Aging; Frailty; SUMOylation; Ubc9; SENP1; Cortex; Synaptosome; Blood plasma;
An overview of the possible therapeutic role of SUMOylation in the treatment of Alzheimer's disease
Keywords: SUMOylation; Alzheimer; Ginkgolic acid; Anacardic acid; Natural substances; Oxidative stress;
Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells
Keywords: PML; Arsenic; Solubility; SUMOylation; DAXX; MDM2;
Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy
Keywords: ANP; atrial natriuretic protein; ANG II; angiotensin II; ARB; angiotensin II receptor type I blocker; BNP; brain natriuretic protein; HSF2; heat shock transcription factor 2; IGF-IIR; insulin-like growth factor receptor II; NRVM; neonatal rat ventricular
A novel transcription factor Rwdd1 and its SUMOylation inhibit the expression of sqr, a key gene of mitochondrial sulfide metabolism in Urechis unicinctus
Keywords: Urechis unicinctus; Sulfide; Quinine oxidoreductase gene; RWD domain-containing 1; Transcription factor; Transcriptional regulation; SUMOylation;
ASC-J9® suppresses prostate cancer cell invasion via altering the sumoylation-phosphorylation of STAT3
Keywords: ASC-J9; Prostate cancer; Invasion; Sumoylation; STAT3;
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function
Keywords: Signal transducer and activator of transcription 1; gain of function; sumoylation; small ubiquitin-related modifier; IFN-γ; Rhodococcus species infection; CMC; Chronic mucocutaneous candidiasis; GFP; Green fluorescent protein; GOF; Gain of function; IP10
Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis
Keywords: Cell cycle; SUMOylation; Meiosis; Kinetochore; Centrosome; Spindle; MTOC;
SIZ1-mediated SUMOylation during phosphate homeostasis in plants: Looking beyond the tip of the iceberg
Keywords: Arabidopsis thaliana (Arabidopsis); Oryza sativa (rice); Phosphate (Pi) deficiency; Post-translation modifications; SUMOylation; AtSIZ1 orthologs; Phylogenetic analysis; SUMOylation targets;
Research articleSumoylation regulates the transcriptional activity of different human NFAT isoforms in neurons
Keywords: NFAT Ca2+-regulated transcription factor; Neuronal activity; Sumoylation; Transactivation; Neurons;
Detection of ORF6 protein associated with latent KHV infection
Keywords: KHV; ORF6 protein; B cell; Koi; Latent herpesvirus; Sumoylation;
SUMOylation of IQGAP1 promotes the development of colorectal cancer
Keywords: IQGAP1; Colorectal carcinoma; SUMOylation; SUMO1;
Phosphorylated eEF2 is SUMOylated and induces cardiomyocyte apoptosis during myocardial ischemia reperfusion
Keywords: Myocardial ischemia reperfusion; Cardiomyocyte apoptosis; eEF2; Phosphorylation; SUMOylation;
Archival ReportSumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development
Keywords: Cerebellum; FOXP2; Motor function; Purkinje cells; Sumoylation; Vocal communication;
GATA5 SUMOylation is indispensable for zebrafish cardiac development
Keywords: WT; wild-type; UBC9; ubiquitin-conjugating enzyme E2I; SAE1/SAE2; SUMO-activating enzyme subunit 1 and 2; PML; promyelocytic leukemia protein; SENP2; sentrin-specific protease 2; SENP5; sentrin-specific protease 5; ASDs; atrial septal defects; VSDs; ventr
Original ArticleSUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions
Keywords: SUMOylation; Lats1; Hippo signaling; Tumor suppressor; SUMO; Small ubiquitin-like modifier; Lats; large tumor suppressor; YAP; Yes-associated protein; TAZ; transcriptional co-activator with PDZ-binding motif; Tead; TEA domain transcription factor; CTGF; c
Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation
Keywords: Glucokinase; MIN6 cells; Pancreatic islets; Beta-cells; SUMOylation; Nuclear localization signal; Human islets; GK; glucokinase; hGK; human glucokinase; GKRP; glucokinase regulatory protein; MIN6; mouse insulinoma cells; NLS; nuclear localization signal;
ReviewUbiquitin-like modifications in the DNA damage response
Keywords: Ubiquitin-like modifiers (UBLs); DNA damage response; SUMOylation; NEDDylation; ISGylation; FATylation; UFMylation;
SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6
Keywords: ER stress; UPR; ATF6; SUMOylation; CFTR; Transcription;
Degradation of nuclear Ubc9 induced by listeriolysin O is dependent on K+ efflux
Keywords: Cholesterol-dependent cytolysin; SUMOylation; Protein degradation;
Proteomics analysis of the endogenous, constitutive, leaf SUMOylome
Keywords: 3D gel electrophoresis; Post translational modification; SUMOylation; Endogenous SUMO conjugates; Solanum tuberosum; IMAC; immobilized metal ion affinity chromatography; IAA; iodoacetamide; NEM; N-ethylmaleimide; PTM; post-translational modification; TCA;
Maternal SENP7 programs meiosis architecture and embryo survival in mouse
Keywords: meiosis I/II; the first/second meiotic division; MI/MII; metaphase I/II; MPF; M-phase promoting factor; Cdk1; Cyclin-dependent kinase 1; APC; anaphase promoting complex; BrdU; bromodeoxyuridine; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectas
Theobromine suppresses adipogenesis through enhancement of CCAAT-enhancer-binding protein β degradation by adenosine receptor A1
Keywords: AC; adenylate cyclase; AR; adenosine receptor; CCPA; 2-Chloro-N6-cyclopentyladenosine; C/EBP; CCAAT/enhancer-binding-protein; CRE; cAMP response elements; CREB; cAMP response element-binding protein; FAS; fatty acid synthase; IBMX; isobutylmethylxanthine;
Sub-cellular localization specific SUMOylation in the heart
Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d
Mitochondrial E3 ubiquitin ligase 1: A key enzyme in regulation of mitochondrial dynamics and functions
Keywords: Mitochondrial E3 ubiquitin ligase 1; Ubiquitination; SUMOylation; Mitochondrial dynamic; Apoptosis; NF-κB;
Identification of new SUMO activating enzyme 1 inhibitors using virtual screening and scaffold hopping
Keywords: Sumoylation; SUMO; SUMO E1 inhibitor; Virtual screening; Scaffold hopping
SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells
Keywords: Pregnane X receptor; SUMOylation; Transcriptional activity; CYP3A4; P-gpSUMO, small ubiquitin-related modifier; PXR, pregnane X receptor; RIF, rifampicin; CYP3A4, cytochrome P450 3A4; P-gp, p-glycoprotein; MDZ, midazolam; 1′-OHMDZ, 1′-Hydroxymidazolam; Rh
SUMOylation regulates nuclear localization and stability of TRAIP/RNF206
Keywords: TRAIP; SUMOylation; Subcellular localization; Protein degradation;
Pharmacological treats for SUMO addicts
Keywords: SUMOylation; Cancer; Personalized medicine; NOTCH1; MYC; KRAS; SUMOylation inhibitors;
Proteostasis and SUMO in the heart
Keywords: Heart diseases; PTMs; SUMOylation; Proteostasis;
DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission
Keywords: DJ-1; Myocardial ischemia; Mitochondrial fission; SUMOylation;