Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation
Keywords: توسعه سلول T; Foxa1; Foxa2; T-cell development; TEC; Thymus; Treg;
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Epigenetic mechanisms regulating T-cell responses
Keywords: توسعه سلول T; Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo
Immune deficiencies, infection, and systemic immune disordersIdentification of checkpoints in human T-cell development using severe combined immunodeficiency stem cells
Keywords: توسعه سلول T; SCID; thymus; NSG; IL2RG; IL7RA; adenosine deaminase; Artemis; T-cell development; B-cell development; ADA; Adenosine deaminase; BM; Bone marrow; DN; Double negative; HSPC; Hematopoietic stem and progenitor cell; IGH; Immunoglobulin heavy chain; IL2RG; IL
SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine
Keywords: توسعه سلول T; Immune Regulation; Intestinal Epithelium; T-Cell Development; Immunity; APC; allophycocyanin; CX3CR1; CX3CL chemokine receptor 1; EAT; Ewing's sarcoma-associated transcript; FACS; fluorescence-activated cell sorting; FITC; fluorescein isothiocyanate; GF
Partial defects of T-cell development associated with poor T-cell function
Keywords: توسعه سلول T; Immunodeficiency; T-cell development; thymus; autoimmunity; toleranceAIRE, Autoimmune regulator; CMV, Cytomegalovirus; CRAC, Calcium release–activated channel; DOCK8, Dedicator of cytokinesis 8; InsP3, Inositol 1,4,5-trisphosphate; ITK, IL-2–inducible tyr
Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ageing
Keywords: توسعه سلول T; TREC; T-cell development; T-cell proliferation; Ageing
Regulatory role of mouse epidermal growth factor-like protein 8 in thymic epithelial cells
Keywords: توسعه سلول T; EGFL8; Intercellular adhesion molecule-1; T-cell development; Thymopoietic factors;
T-helper 17 and Interleukin-17–Producing Lymphoid Tissue Inducer-Like Cells Make Different Contributions to Colitis in Mice
Keywords: توسعه سلول T; Immune Regulation; T-Cell Development; Mouse Model; Inflammatory Bowel DiseaseBM, bone marrow; GALT, gut-associated lymphoid tissue; GFP, green fluorescent protein; GITR, glucocorticoid-induced tumour necrosis factor receptor; IFN, interferon; IL, interle
Dysregulation of CD1d-Restricted Type II Natural Killer T Cells Leads to Spontaneous Development of Colitis in Mice
Keywords: توسعه سلول T; IBD; Crohn's Disease; Immune Regulation; T-Cell Development; α-GalCer; α-galactosylceramide; DSS; dextran sulfate sodium; HBSS; Hank's balanced salt solution; IFN; interferon; IL; interleukin; NK; natural killer; TCR; T-cell receptor;
Inhibition of Interleukin-17 Promotes Differentiation of CD25- Cells Into Stable T Regulatory Cells in Patients With Autoimmune Hepatitis
Keywords: توسعه سلول T; Immunotherapy; Liver Inflammation; Immune Regulation; T-Cell Development; AIH; autoimmune hepatitis; ANA; anti-nuclear antibody; HS; healthy subjects; IFN; interferon; IL; interleukin; MFI; mean fluorescence intensity; ngTreg; newly generated T regulatory
Cytokines and culture medium have a major impact on human in vitro T-cell differentiation
Keywords: توسعه سلول T; T-cell development; Thymopoiesis; Lymphopoiesis; Notch; OP9-Delta1
Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases
Keywords: توسعه سلول T; Immune System; T-Cell Development; TGF-β; Immune SuppressionIFN, interferon; IL, interleukin; LP, lamina propria; MLN, mesenteric lymph node; PB, peripheral blood; TCR, T-cell receptor; TGF, transforming growth factor; Th17, T-helper interleukin-17–produc
Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells
Keywords: توسعه سلول T; Inflammatory Bowel Disease; Mouse Model; T-Cell Development; Immune ResponseCTLA, cytotoxic T lymphocyte−associated antigen; GFP, green fluorescent protein; Gr, Group; IBD, inflammatory bowel disease; IFN, interferon; LP, lamina propria; mRNA, messenger R
Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
Keywords: توسعه سلول T; Gfi1; Mouse; B-cell development; T-cell development; Il-7R; Transcription factor; CD4; CD8; Th2; Treg; Th17
Expression of T-cell markers during Atlantic halibut (Hippoglossus hippoglossus L.) ontogenesis
Keywords: توسعه سلول T; Teleost; T-cell receptor; Recombination activation gene; CD3; CD4; CD8; Lck; ZAP-70; T-cell development; T-cell maturation
Characterization of ζ-associated protein, 70 kd (ZAP70)-deficient human lymphocytes
Keywords: توسعه سلول T; T-cell development; TH2 response; T cells; thymopoiesis; T-cell receptor exclusion circle; T-cell rearrangement; ZAP70; ADA; Adenosine deaminase; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4; DP; Double positive; DN; Double negative; FITC; fluore
Age-associated plasticity of α1-adrenoceptor-mediated tuning of T-cell development
Keywords: توسعه سلول T; Ageing; Noradrenaline; α1-adrenoceptors; Rat thymus; T-cell development;
Transcription factor expression dynamics of early T-lymphocyte specification and commitment
Keywords: توسعه سلول T; T-cell development; Notch; Thymus; Lineage commitment; Hematopoiesis
An in vivo functional genetic screen for suppressors of the Rag1â/â T-cell defect
Keywords: توسعه سلول T; DN; double negative CD4âCD8â; DP; double positive CD4+CD8+; FTOC; fetal thymic organ culture; GFP; green fluorescent protein; TCR; T-cell receptor; TCRβ; T-cell receptor β chain; Rag; recombinase activating gene; T-cell development; T-cell leukaemia
Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination
Keywords: توسعه سلول T; T-cell development; Lineage commitment; Mast cells; Dendritic cells; Transcription factor
Graft-versus-host-like disease complicating thymoma: Lack of AIRE expression as a cause of non-hereditary autoimmunity?
Keywords: توسعه سلول T; Thymoma; Graft-versus-host-disease; Autoimmunity; Microsatellite; AIRE; FOXP3; T-cell development
The glycosylation of thymic microenvironments: A microscopic study using plant lectins
Keywords: توسعه سلول T; Plant; Plant lectin; Lectin; Thymus; T-cell development; T-cell; T-cell differentiation; Thymocyte; C-type lectin; DC-SIGN; DEC-205; Mannose receptor; Perivascular space (PVS); Glycosylation; Carbohydrate; Immature; Mature; Thymic microenvironment; Glycoc
Subversion of T lineage commitment by PU.1 in a clonal cell line system
Keywords: توسعه سلول T; T-cell development; Hematopoiesis; Transcription factors; Thymocyte; Gene regulatory networks; Myeloid cells;