Keywords: زبان ها; Therapeutic genome editing; Non-viral delivery; Nuclease-mediated genome editing; Oligonucleotide-mediated genome editing; CRISPR/Cas9; Peptide nucleic acid; BBB; blood brain barrier; CMV; cell-derived membrane vesicle; CRISPR; Clustered Regularly Intersp
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: زبان ها; DNA; deoxyribonucleic acid; Ï3 LC; PUFA omega-3 long-chain polyunsaturated fatty acids; TNT; trinitrotoluene; DBTL; design/build/test/learn; TAG; triacylglycerol; ZFN; zinc finger nuclease; TALEN; transcription activator-like effector nucleases; RNA; rib
Keywords: زبان ها; Genome editing; ZFN; TALEN; CRISPR/Cas9; Fish; Teleosts;
Keywords: زبان ها; EB; epidermolysis bullosa; BMZ; basement membrane zone; EBS; epidermolysis bullosa simplex; JEB; junctional epidermolysis bullosa; DEB; dystrophic epidermolysis bullosa; KS; kindler syndrome; DEJ; dermal-epidermal junction; PTC; premature termination codo
Keywords: زبان ها; Breeding methods; Chrysanthemum morifolium; CRISPR/Cas9; Genome editing; Ornamental plants; Transgenic technologies; 4CL; 4-coumarate:coenzyme A ligase; C3H; coumarate 3-hydroxylase; C4H; cinnamate 4-hydroxylase; CCD4; carotenoid cleavage dioxygenase 4; C
Keywords: زبان ها; AA; alopecia areata; CRISPR/Cas9; clustered, regularly interspaced, short palindromic repeat/cas 9; HR; homologous recombination; iPSC; induced pluripotent stem cell; MSC; mesenchymal stromal cell; NHEJ; nonhomologous end-joining; RDEB; recessive dystroph
Keywords: زبان ها; Hematopoietic stem cell transplantation; gammaretroviral vector; lentiviral vector; gene editing; site-specific endonuclease; zinc finger nuclease; CRISPR/Cas9; ADA-SCID; Adenosine deaminase-deficient severe combined immunodeficiency; CGD; Chronic granu
Keywords: زبان ها; Recombinase-based gene circuits; CRISPR-based gene circuits; Cellular computing; ADC; analog-to-digital converter; att; attachment sites; BLADE; Boolean logic and arithmetic through DNA excision; Cas; CRISPR-associated nuclease; CRISPR; clustered regularl
Keywords: زبان ها; CRISPR-Cas9; Kluyveromyces lactis; Kluyveromyces marxianus; Scheffersomyces stipitis; Yarrowia lipolytica; Hansenula polymorpha; Pichia pastoris; HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; double strand break; CRISPR; Clustered re
Keywords: زبان ها; Secondary metabolism; Genome editing; TALEN; CRISPR-Cas9; Hybrid metabolites; Epigenome editing;
Keywords: زبان ها; Meganuclease; TALEN; Zinc finger nuclease; CRISPR/Cas9; Regulatory switch; Hammerhead ribozyme;
Keywords: زبان ها; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
Keywords: زبان ها; REM; RNA-guided endonuclease mediated; EEM; Engineered endonuclease mediated; CRISPR/Cas; Clustered regularly interspersed short palindromic repeats/ CRISPR associated sequence; TALE; Transcription Activator-like Effectors; TALEN; Transcription Activator-
Keywords: زبان ها; 11KT; 11-ketotestosterone; 17bhsd; 17β-hydroxysteroid dehydrogenase; 17P; 17α-hydroxyprogesterone; 17,20bP; 17,20β-dihydroxy-4-pregnen-3-one; 20b-HSD; 20β-hydroxysteroid dehydrogenase; 20βS; 17,20β,21-trihydroxy-4-pregnen-3-one; actRIIB; activin rec
Keywords: زبان ها; ZFN; TALEN; CRISPR/Cas9; Human pluripotent stem cells
Keywords: زبان ها; AAV; Adeno associated virus; ABC; ATP-binding cassette; ACMG; American College Medical Genetics; AH; Ancestral Haplotype; ASL; airway surface liquid; ATP; Adenosine triphosphate; cas; CRISPR associated; CF; Cystic fibrosis; CFTR; Cystic Fibrosis Transmemb
Keywords: زبان ها; CRISPR/Cas9; Clustered regularly interspaced short palindromic repeats/CRISPR-associated; GBS; genotyping by sequencing; GEBV; genomic estimated breeding values; GS; genomic selection; GWAS; genome-wide association studies; LD; linkage disequilibrium; MAG
Keywords: زبان ها; ARS; autonomously replicating sequence; CEN; centromere; CRISPR; Clustered, Regularly Interspaced, Short Palindromic Repeats; DSB; double strand break; GFP; green fluorescent protein; GRAS; Generally Regarded As Safe; gRNA; guide RNA (for CRISPR); HR; hom
Keywords: زبان ها; new plant breeding techniques; cisgenesis; intragenesis; TALEN; CRISPR-Cas9; early flowering
Keywords: زبان ها; Zebrafish; Next generation sequencing; Gene mutations; TALEN; CRISPR/Cas9
Keywords: زبان ها; Genome editing; ZFN; TALEN; CRISPR; Hematological disease;
Keywords: زبان ها; AAV4; adeno-associated virus serotype 4; BDNF; brain-derived neurotrophic factor; bFGF; fibroblast growth factor 2; BME; β-mercaptoethanol; BMP; bone morphogenetic protein; Cas9; CRISPR associated protein 9; Cla; claustrum; CN; caudate nucleus; CRISPR; c
Keywords: زبان ها; rewilding; reverse breeding; organic agriculture; TALEN; CRISPR-Cas9; cisgenesis
Keywords: زبان ها; synthetic biology; sequence-specific nuclease; zinc-finger nuclease; TALEN; CRISPR/Cas; genome engineering
Keywords: زبان ها; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator protein; CFTR2; Correctors; Potentiators; Trial end-points; Amil; Amiloride; AMP; Accelerating Medicine Partnership; ANO; anoctamins; AONs; antisense oligonucleotides; ASL; airway surfac
Keywords: زبان ها; 4CL; 4-coumaroyl CoA ligase; ADME/T; absorption, distribution, metabolism, excretion (and toxicity); BIA; benzylisoquinoline alkaloid; C4H; cinnamate 4-hydroxylase; CoA; coenzyme A; CRISPR/Cas9; clustered regulatory interspaced short palindromic repeat/CR
Keywords: زبان ها; Engineered nuclease; ZFN; TALEN; RGEN; NHEJ; Knockout mouse; Microinjection
Keywords: زبان ها; Transgenic; TALEN; Farm animal
Modified T-cells (using TCR and CTAs), chimeric antigen receptor (CAR) and other molecular tools in recent gene therapy
Keywords: زبان ها; Clinical trials; Disorders; Gene therapy; Molecular biology; Pharmacotherapy; Vector; PID; Primary immunodeficiencies; ADA; Adenosine deaminase; CAR; Chimeric antigen receptors; TCR; T cell receptor; CTAs; Cancer testis antigens; TALEN; Transcription acti
SKLPT imaging: Efficient in vivo pre-evaluation of genome-editing modules using fluorescent protein with peroxisome targeting signal
Keywords: زبان ها; CRISPR-Cas9; Fluorescent reporter; GFP; PTS1; TALEN; ZFN;
CRISPR/Cas9-mediated genome editing of the fatty acid desaturase 2 gene in Brassica napus
Keywords: زبان ها; Brassica napus; Breeding; Fatty acid desaturase 2 gene; Genome editing; Oleic acid; BC1; first generation of backcross; BC1S1; self-pollinated progenies of BC1; CAPSs; Cleaved amplified polymorphic sequences; CRISPR; Clustered regularly interspaced short
Generation of H1 PAX6WT/EGFP reporter cells to purify PAX6 positive neural stem/progenitor cells
Keywords: زبان ها; Neural stem cells; Human embryonic stem cells; TALEN;
Impaired mammary tumor formation and metastasis by the point mutation of a Smad3 linker phosphorylation site
Keywords: زبان ها; IVIS; in vivo imaging system; qPCR; quantitative polymerase chain reaction; TALEN; transcription activator-like effector nuclease; TNBC; triple negative breast cancer; FACS; fluorescence-activated cell sorting; ANOVA; analysis of variation; TGF-β; Smad3
Lipid productivity in TALEN-induced starchless mutants of the unicellular green alga Coccomyxa sp. strain Obi
Keywords: زبان ها; AGPase; ATP:α-d-glucose-1-phosphate adenylyltransferase; AGPL; the large subunit of ATP:α-d-glucose-1-phosphate adenylyltransferase; TALEN; transcription activator-like effector nuclease; Biofuel; Starch; Green alga; α-d-Glucose-1-phosphate adenylyltra
Precise immune tolerance for hPSC derivatives in clinical application
Keywords: زبان ها; AAV; adeno-associated virus; ATIIC; lung alveolar epithelial type II cell; B2M; b-2-microglobulin; BAC; bacterial artificial chromosome; CIITA; class-II MHC trans-activator; CP hESC; hESC lines constitutively expressing CTLA4Ig and programmed death-ligand
Application and development of genome editing technologies to the Solanaceae plants
Keywords: زبان ها; Genome editing; Nuclease; Targeted mutagenesis; AGL; agamous-like; AID; activation-induced cytidine deaminase; ALOG; Arabidopsis LSH1 and Oryza G1; ANT; anthocyanin mutant; ARF; auxin-response factor; Aux; auxin-induced; BAK; brassinosteroid kinase; BOP;
sox2 and sox3 cooperate to regulate otic/epibranchial placode induction in zebrafish
Keywords: زبان ها; SoxB1; Pluripotency; Progenitors; TALEN; CRISPR/Cas9;
Tripartite motif-containing (TRIM) 21 negatively regulates intestinal mucosal inflammation through inhibiting TH1/TH17Â cell differentiation in patients with inflammatory bowel diseases
Keywords: زبان ها; Tripartite motif-containing 21; inflammatory bowel disease; CD4+ T cells; mucosal inflammation; TH1; TH17; A-CD; Active Crohn disease; A-UC; Active ulcerative colitis; CD; Crohn disease; CDAI; Crohn's Disease Activity Index; HC; Healthy control subject; I
The potential and challenges of CRISPR-Cas in eradication of hepatitis B virus covalently closed circular DNA
Keywords: زبان ها; CHB; chronic hepatitis B; HBV; hepatitis B virus; NA; nucleos(t)ide analogue; cccDNA; covalently closed circular DNA; guide RNA; gRNA; NTCP; sodium taurocholate cotransporting polypeptide; RC-DNA; relaxed circular DNA; pgRNA; pregenomic RNAs; HBsAg; HBV s
Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway
Keywords: زبان ها; APAP; acetaminophen; Nrf2; nuclear factor erythroid 2-related factor 2; Andro; andrographolide; HSCs; hepatic stellate cells; ROS; reactive oxygen species; ECMs; extracellular matrix proteins; Egr1; early growth factor 1; Keap1; kelch-like ECH-associated
Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell
Keywords: زبان ها; NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate
Short CommunicationPtAUREO1a and PtAUREO1b knockout mutants of the diatom Phaeodactylum tricornutum are blocked in photoacclimation to blue light
Keywords: زبان ها; Aureochrome; Blue light; Red light; Light acclimation; TALEN; Diatoms;
Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview
Keywords: زبان ها; HEase; homing endonuclease; ZFN; zinc finger nuclease; TALEN; TAL-effector nuclease; DSB; double strand break; dCas9; catalytically inactive (dead) Cas9; RNP; ribonucleoprotein; Genome editing; CRISPR; Cas9; High-throughput methods; PAM library;
Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures
Keywords: زبان ها; Vegfa; TALEN; Arterial-venous specification; Zebrafish; AMCtA; anterior mesencephalic central artery; BA; basilar artery; CtAs; central arteries; BCA; basal communicating artery; DA; dorsal aorta; DLAV; dorsal longitudinal anastomotic vessels; DLV; dorsal
BIBAC-GW-based vectors for generating reporter lines for site-specific genome editing in planta
Keywords: زبان ها; BIBAC; Binary vector based on Bacterial artificial chromosomes; ChIP; Chromatin ImmunoPrecipitation; CRISPR; Clustered Regularly-Interspaced Short Palindromic Repeat; GW; Gateway; NLS; nuclear localization signal; Nos; Nopaline Synthase; ODM; Oligonucleot
Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells
Keywords: زبان ها; hiPS cell(s); human induced pluripotent stem cell(s); KI; knock-in; TAp63; transactivating p63; ÎNp63; N-terminally truncated p63; ZFNs; zinc-finger nucleases; TALENs; transcription activator-like effector nucleases; SEAM; self-formed ectodermal autonomo
A fast and reliable strategy to generate TALEN-mediated gene knockouts in the diatom Phaeodactylum tricornutum
Keywords: زبان ها; Phaeodactylum tricornutum; TALEN; PtAUREO1a knockout; Blue light-dependent transcription factor;
GATA5 SUMOylation is indispensable for zebrafish cardiac development
Keywords: زبان ها; WT; wild-type; UBC9; ubiquitin-conjugating enzyme E2I; SAE1/SAE2; SUMO-activating enzyme subunit 1 and 2; PML; promyelocytic leukemia protein; SENP2; sentrin-specific protease 2; SENP5; sentrin-specific protease 5; ASDs; atrial septal defects; VSDs; ventr
ReviewCell-penetrating peptides (CPPs): From delivery of nucleic acids and antigens to transduction of engineered nucleases for application in transgenesis
Keywords: زبان ها; Cre; (causes recombination) recombinase - a 35Â kDa integrase protein; loxP; (locus of crossing-over [x]) site - two symetrical 13âbp protein-binding regions separated by an 8-bp spacer region; ZFN; zinc-finger nucleases; TALEN; stranscription activator
The histone lysine methyltransferase Ezh2 is required for maintenance of the intestine integrity and for caudal fin regeneration in zebrafish
Keywords: زبان ها; bp; base pair; dpf; days post fertilization; dpa; days post amputation; ezh2; enhancer of zeste homolog 2 (polycomb repressive complex 2 subunit); hpf; hours post fertilization; gcga; glucagon a; ins; insulin; NMD; nonsense-mediated decay; nt; nucleotide;