دانلود مقالات ISI درباره هدف از رپامایسین + ترجمه فارسی

Genome-wide identification and analysis of FK506-binding protein family gene family in strawberry (Fragaria Ã— ananassa)

Keywords: هدف از رپامایسین; FKBPs; FK506-binding proteins; FKBd; FK506-binding domain; PPIase; peptidyl-prolylcis-trans isomerase; TPR; tetratricopeptide repeat; CaM-BDs; calmodulin-binding domains; SD; single-domain; MD; multidomain; TOR; target of rapamycin; HSP90; heat streak pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

To divide or not to divide: A key role of Rim15 in calorie-restricted yeast cultures

Keywords: هدف از رپامایسین; CFU; colony forming units; EDGE; empirical analysis of digital gene expression data in R v 1.1.291; MIPS; Munich Information Centre for Protein Sequences; PDS; post-diauxic shift; PHO; Pho80-Pho85 kinase; PKA; cAMP-dependent protein kinase; qs; specific

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Create and preserve: Proteostasis in development and aging is governed by Cdc48/p97/VCP

Keywords: هدف از رپامایسین; AAA; ATPase associated with diverse cellular activities; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; adenosine monophosphate activated kinase; Cdc48/CDC-48; cell division cycle protein 48; DUB; de-ubiquitylating enzyme; ERAD; endopl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy

Keywords: هدف از رپامایسین; CMC; critical micelle concentration; DihepPC; 1,2-diheptanoyl-sn-glycero-3-phosphocholine; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DPC; dodecylphosphocholine; FAT(C); FRAP, ATM, TRRAP (C-terminal); GB1; B1 immunoglobulin binding domain of strep

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: Cloning and tissue expression of mTOR, Akt, Rheb, and p70 S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis

Keywords: هدف از رپامایسین; Target of rapamycin; Rheb; Akt; p70 S6 kinase; Molting; Crustacea; Y-organ; Ecdysteroid

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Honeybees and cell lines as models of DNA methylation and aging in response to diet

Keywords: هدف از رپامایسین; DNMT; DNA methyltransferase; TOR; target of rapamycin; IGF1/insulin; insulin-like growth factor 1/insulin; AMPK; AMP-dependent protein kinase; SIRT; sirtuin; 10-HDA; 10-hydroxydecanoic acid; PGC-1α; peroxisome proliferator-activated receptor gamma coacti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions

Keywords: هدف از رپامایسین; AED; after egg deposition; CC; corpora cardiac; Dilp; Drosophila insulin-like peptide; IGF; insulin-like growth factors; IGFBP; insulin-like growth factor binding proteins; IIS; insulin/insulin-like growth factor signaling; Imp-L2; Imaginal morphogenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy, polyphenols and healthy ageing

Keywords: هدف از رپامایسین; AD; Alzheimer's disease; AMP; adenosine monophosphate; AMPK; adenosine monophosphate activated protein kinase; APP; amyloid beta precursor protein; Atg; autophagy (related gene); ATP; adenosine triphosphate; AV; autophagic vacuoles; Aβ; amyloid beta; Bcl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

The role of MAP4K3 in lifespan regulation of Caenorhabditiselegans

Keywords: هدف از رپامایسین; MAP4K3; Target of rapamycin; mTOR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Target of rapamycin (TOR) controls vitellogenesis via activation of the S6 kinase in the fat body of the tick, Haemaphysalis longicornis

Keywords: هدف از رپامایسین; Tick; Fat body; Vitellogenin; Target of rapamycin; S6K; GATA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SLC7 amino acid transporters of the yellow fever mosquito Aedes aegypti and their role in fat body TOR signaling and reproduction

Keywords: هدف از رپامایسین; AA, amino acids; CAT, cationic amino acid transporter; FBCM, fat body culture media; HAT, heterodimeric amino acid transporter; SLC7, solute carrier 7 family; TOR, target of rapamycinSLC7 transporter; Mosquito; Target of rapamycin; Amino acid; Aedes aegyp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Gender and the regulation of longevity: Implications for autoimmunity

Keywords: هدف از رپامایسین; Gender; Aging; Longevity; Immune response; Autoimmunity; Sex chromosome; Telomere; Mitochondria; Oxidative stress; Target of Rapamycin; Insulin/IGF-1; p53; Reactive oxygen species

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Keywords: هدف از رپامایسین; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindolacetic acid; AD; Alzheimer's disease; DA; Dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; EPI; Epinephrine; HPLC; high performance liquid chromatography; HVA; homovanillic acid; LTD; long-term depression

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation

Keywords: هدف از رپامایسین; Tor1; Target of rapamycin; RNAPII; RNA polymerase II; CTD; C-terminal domain; Rrd1; resistant to rapamycin deletion 1; Elc1; Elongin C; 4-NQO; 4-nitroquinoline-1-oxide; Rapamycin; RNA polymerase II degradation; Ubiquitylation; Peptidyl prolyl isomerase; R

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Mitochondria, reactive oxygen species, and chronological aging: A message from yeast

Keywords: هدف از رپامایسین; Chronological lifespan; Mitochondrial theory of aging; Mitohormesis; Hormetic ROS; Oxidative phosphorylation; Target of rapamycin; Reactive oxygen species; Saccharomyces cerevisiae

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The controversial links among calorie restriction, SIRT1, and resveratrol

Keywords: هدف از رپامایسین; Ac; acetate; AMPK; AMP-activated kinase; CAECs; coronary arterial endothelial cells; CR; calorie restriction; CSE; cigarette smoke extract; eNOS; endothelial nitric oxide synthase; EX-527; 6-chloro-2,3,4,9-tetrahydro-1-H-carbazole-1-carboxamide; F⁎; flu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The localisation of PtdIns3P in Drosophila fat responds to nutrients but not insulin: a role for Class III but not Class II phosphoinositide 3-kinases

Keywords: هدف از رپامایسین; AEL; after egg lay; eL3; early third larval instar; hVps15; mammalian vacuolar protein sorting 15 homologue; hVps34; mammalian vacuolar protein sorting 34 homologue; L3; third larval instar; MTM; myotubularin; PI3K; phosphoinositide 3-kinase; S6K1; S6 kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of dietary choline on growth, intestinal enzyme activities and relative expressions of target of rapamycin and eIF4E-binding protein2 gene in muscle, hepatopancreas and intestine of juvenile Jian carp (Cyprinus carpio var. Jian)

Keywords: هدف از رپامایسین; Body composition; Choline; Cyprinus carpio var. Jian; Gene expression; Intestinal enzyme activity; Target of rapamycin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Nectarine promotes longevity in Drosophila melanogaster

Keywords: هدف از رپامایسین; DR; dietary restriction; sod1; superoxide dismutase 1; TOR; target of rapamycin; JNK; Jun kinase; 8-oxoG; 8-oxoguanine; SY; sugar-yeast extract; RNAi; RNA interference; UAS-sod1IR; UAS-sod1 inverted repeat; da-Gal4; daughterless-Gal4; DAMS; Drosophila A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Keywords: هدف از رپامایسین; 4E-BP1; 4E binding protein 1; 5′UTR; 5′ untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5′-AMP-activated protein kinase; AMPK α1−/−; AMPK α1 subunit knockout; AMPKα1−/−α2−/−; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Signal-transduction networks and the regulation of muscle protein degradation

Keywords: هدف از رپامایسین; 15(S)-HETE; 15(S)-hydroxyeicosatetraenoic acid; ACh; acetylcholine; Akt; protein kinase B; CNTF; ciliary neurotrophic factor; EGF; epidermal growth factor; FGF; fibroblast growth factor; FOXO; forkhead transcription factor; Grb2; growth factor receptor bo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Relationship of electrophilic stress to aging

Keywords: هدف از رپامایسین; 4-HNE; 4-hydroxynon-2-enal; GST; glutathione transferase; Hsp; heat shock protein; I/R; ischemia/reperfusion; IIS; insulin/insulin-like signaling; MUFA; monounsaturated fatty acid; PI3K; phosphatidylinositol 3-kinase; PUFA; polyunsaturated fatty acid; RNA

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: Role of Ca2+/calmodulin and receptor tyrosine kinase

Keywords: هدف از رپامایسین; PTTH; prothoracicotropic hormone; ERK; extracellular signal-regulated kinase; PKC; protein kinase C; PMA; phorbol 12-myristate acetate; MAPK; mitogen-activated protein kinase; TBS; Tris-buffered saline; MW; molecular weight; TOR; target of rapamycin; PVDF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Autophagy: A lysosomal degradation pathway with a central role in health and disease

Keywords: هدف از رپامایسین; Aβ; amyloid β; ER; endoplasmic reticulum; HOPS; homotypic vacuole fusion and protein sorting; LAMP; lysosome associated membrane protein; MHC; major histocompatibility complex; MVB; multivesicular body; NSF; N-ethylmaleimide-sensitive fusion protein; PA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

A fast and simple method to prepare the FKBP-rapamycin binding domain of human target of rapamycin for NMR binding assays

Keywords: هدف از رپامایسین; Target of rapamycin; TOR; FKBP; Refolding; Inclusion body; HPLC; NMR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae

Keywords: هدف از رپامایسین; Anopheles gambiae; Oogenesis; Target of rapamycin; p70 S6 kinase; Amino acid signaling

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti

Keywords: هدف از رپامایسین; Insulin receptor; Akt; S6K; Target of rapamycin; RNAi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase

Keywords: هدف از رپامایسین; Protein phosphatase; PP2A; Target of rapamycin; S6 kinase; Phosphorylation site; Regulation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling

Keywords: هدف از رپامایسین; Sin1; SAPK-interacting protein 1; SAPK; stress-activated protein kinase; RIP3; Ras-interacting protein 3; TOR; target of rapamycin; JNK; c-Jun N-terminal kinase; ERK1/2; extracellular regulated kinase 1/2; PH; pleckstrin homology; RBD; Raf-like Ras-bindin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Connecting cell-cycle activation to neurodegeneration in Drosophila

Keywords: هدف از رپامایسین; Tau; Cell cycle; Neurodegeneration; Alzheimer's disease; TOR; Target of rapamycin; Mitogenic signaling; Apoptosis; Drosophila melanogaster; Invertebrate model

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine

Keywords: هدف از رپامایسین; Intestine; Target of rapamycin; mTOR; TORC1; Zebrafish; Organogenesis; Morphogenesis; Intestinal development

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation

Keywords: هدف از رپامایسین; Aplysia; learning and memory; phosphoinositide dependent kinase I; persistent protein kinase; rapamycin; autophosphorylation; PDBu; phorbol dibutyrate; PDK-1; phosphoinositide-dependent kinase I; PI-3 kinase; phosphoinositide-3 kinase; PKC; protein kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Using genome-wide transcriptional profiling to elucidate small-molecule mechanism

Keywords: هدف از رپامایسین; AML; acute myelogenous leukemia; RT-PCR; reverse transcription polymerase chain reaction; SFK; suppressor of FK506; TOR; target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging

Keywords: هدف از رپامایسین; SAGA; transcriptional co-activator complex; SLIK; SAGA-like complex; TOR; target of rapamycin; TFIID; RNA polymerase II promoter transcription initiation factor; mtDNA; mitochondrial DNA; ΔΨm; mitochondrial membrane potential; Metabolism; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

The role of SMG-1 in nonsense-mediated mRNA decay

Keywords: هدف از رپامایسین; NMD; nonsense-mediated mRNA decay; EJC; exon-junction complex; PTC; premature translation termination codon; IC; initial SMG-1-Upf1 complex; PIKK; phosphoinositide 3-kinase related kinase; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3 related;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress

Keywords: هدف از رپامایسین; BSO; buthionine sulfoximine; DMEM; Dulbecco's modified essential medium; EBSS; Earle's Balanced Salts Solution; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; eIF4E-BP; eIF4E-binding protein; FBS; fetal bovine serum; GCS; glutathione cys

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Nutritional regulation of vitellogenesis in mosquitoes: Implications for anautogeny

Keywords: هدف از رپامایسین; Amino acid signaling; Target of rapamycin; GATA;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه