Keywords: Multi-omics data; Data integration; Inter-relationship; Clinical outcome prediction; TCGA; Ovarian cancer;
مقالات ISI (ترجمه نشده)
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Keywords: DELSA; Data-Enabled Life Alliances; EGP; Estonian Genome Project; EuPA; European Proteomics Association; FDA; Food and Drug Administration; HUPO; Human Proteome Organization; IGS; International Genomics Consortium; LMNs; Low- and Middle-income nations; MI
Keywords: Cancer; Genomics; Next-generation sequencing; Report; Variant annotation; CAP; College of American Pathologists; COSMIC; Catalog of Somatic Mutations in Cancer; EMR; electronic medical records; MAF; mutant allele fraction; NCCN; National Comprehensive Can
Decreased expression of TFAP2B in endometrial cancer predicts poor prognosis: A study based on TCGA data
Keywords: TFAP2B; Endometrial cancer; Prognosis; TCGA; GSEA;
KLF15 suppresses cell growth and predicts prognosis in lung adenocarcinoma
Keywords: NSCLC; non-small cell lung cancer; LAUD; lung adenocarcinoma; KLFs; krüppel-like factors; CCK-8; Cell Counting Kit-8; IHC; immunohistochemistry; TCGA; The Cancer Genome Atlas; KLF15; LUAD; Prognosis; Proliferation; CDKN1A/p21; CDKN2A/p15;
Downregulated CDKN1C/p57kip2 drives tumorigenesis and associates with poor overall survival in breast cancer
Keywords: Breast cancer; CDKN1C; p57; Prognosis; TCGA; GSEA;
A 15-long non-coding RNA signature to improve prognosis prediction of cervical squamous cell carcinoma
Keywords: Cervical squamous cell carcinoma; lncRNA signature; TCGA; Prognosis prediction;
Long noncoding RNA CYTOR in cancer: A TCGA data review
Keywords: Long non-coding RNA; CYTOR; Cancer; Prognosis; Meta-analysis; ceRNA; Competing endogenous RNA; COAD; Colon adenocarcinoma; DFS; Disease-free survival; EMT; Epithelial to mesenchymal transition; ESCA; Oesophageal carcinoma; HR; Hazard ratio; KICH; Kidney C
MicroRNA co-expression patterns unravel the relevance of extra cellular matrix and immunity in breast cancer
Keywords: Breast cancer; miRNA; miRNA cluster; miRNA co-expression; Microarray; BC; breast cancer; DCIS; ductal carcinoma in-situ; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ER; estrogen receptor; GSEA; gene set enrichment analysis; IDC;
Protease-activated receptor 2 (PAR2) upregulates granulocyte colony stimulating factor (G-CSF) expression in breast cancer cells
Keywords: Protease-activated receptor; Granulocyte colony stimulating factor; Breast cancer; TCGA; ENMD-1068;
Emerging microRNAs in cancer diagnosis, progression, and immune surveillance
Keywords: Cancer immunity; miR-21; miR-375; oncomiR; Prognostic biomarker; RAS pathway; AKT; serine/threonine-protein kinase; CIP2A; cancerous inhibitor of PP2A; ERK; extracellular-signal-regulated kinase; FFPE; formalin-fixed, paraffin-embedded; HNC; head and neck
Prognostic value of estrogen receptor α and estrogen receptor β in gastric cancer based on a meta-analysis and The Cancer Genome Atlas (TCGA) datasets
Keywords: Estrogen receptor alpha; Estrogen receptor beta; Stomach neoplasms; TCGA; Meta-Analysis;
Mutant cytoskeletal and ECM peptides sensitive to the ST14 protease are associated with a worse outcome for glioblastoma multiforme
Keywords: Cytoskeleton and extra-cellular matrix; HLA; ST14 protease; Glioblastoma multiforme; Immune cell infiltrates; CECMP; cytoskeletal and extra-cellular matrix coding regions; GBM; Glioblastoma multiforme; HUGO; human genome organization; KM; Kaplan-Meier sur
A gene expression profile associated with perineural invasion identifies a subset of HNSCC at risk of post-surgical recurrence
Keywords: Head and neck squamous cell carcinoma; Perineural invasion; The Cancer Genome Atlas (TCGA); Gene expression; ALI; angiolymphatic invasion; CPE; consensus purity estimation score; DFS; disease free survival; ECS; extracapsular spread; FDR; false discovery
Analysis of the miRNA-mRNA-lncRNA network in human estrogen receptor-positive and estrogen receptor-negative breast cancer based on TCGA data
Keywords: ER+; estrogen receptor-positive; ERâ; ER-negative; miRNAs; microRNA; lncRNAs; long non-coding RNAs; C2orf71; chromosome 2 open reading frame 71; ER; estrogen receptor; ncRNA; non-coding RNA; BPs; biological processes; BCAR4; breast cancer anti-estrogen
MicroRNA-876-5p inhibits epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by targeting BCL6 corepressor like 1
Keywords: BCORL1; BCL6 corepressor like 1; HCC; hepatocellular carcinoma; EMT; epithelial-mesenchymal transition; miRNAs; microRNAs; TCGA; The Cancer Genome Atlas; GEO; Gene Expression Omnibus; 3â²-UTR; 3â²-untranslated region; CtBP; C-terminal Binding Protein; C
Decreased expression of serine protease inhibitor family G1 (SERPING1) in prostate cancer can help distinguish high-risk prostate cancer and predicts malignant progression
Keywords: Prostate cancer; Serine protease inhibitor family G1 (SERPING1); Prognosis; TCGA; Oncomine;
A radiosensitivity gene signature and PD-L1 predict the clinical outcomes of patients with lower grade glioma in TCGA
Keywords: Glioma; Radiosensitivity; TCGA; PD-L1; Radiation;
Overexpressed ACBD3 has prognostic value in human breast cancer and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway
Keywords: ACBD3; Acyl-CoA binding domain containing 3; ER; estrogen receptor; PR; progesterone receptor; Her2; human epidermal growth factor receptor-2; CSC; cancer stem cell; BCSC; breast cancer stem cell; EGFR; epidermal growth factor receptor; ACBP; acyl-CoA-bin
LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB
Keywords: ESCC; esophageal squamous cell carcinoma; SEER; Surveillance, Epidemiology, and End Results Program; TCGA; the cancer genome atlas; NORAD; Noncoding RNA Activated by DNA Damage; LINCRNA; long intergenic non-coding RNA; ceRNA; competing endogenous RNA; MTT
Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells
Keywords: SIRT7; sirtuin7; HCC; hepatocellular carcinoma; CCA; cholangiocarcinoma; TCGA; The Cancer Genome Atlas; TNM; tumor-node-metastasis; CDK2; cyclin dependent kinase 2; NAD+; nicotinamide adenine dinucleotide; H3K18Ac; acetylated lysine 18 of histone H3; HDAC
Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis
Keywords: miRNA; microRNA; TCGA; The Cancer Genome Atlas; OS; overall survival;
Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2
Keywords: CCL2; chemokine CC motif ligand 2; CRPC; castration-resistance prostate cancer; AR; androgen receptor; EMT; epithelial-to-mesenchymal transition; SPDEF; SAM pointed domain-containing ETS transcription factor; ADT; androgen-deprivation therapy; PTEN; phosp
Investigation of miR-136-5p key target genes and pathways in lung squamous cell cancer based on TCGA database and bioinformatics analysis
Keywords: LUSC; lung squamous cell cancer; TCGA; the Cancer Genome Atlas; GTEx; genotype-tissue expression; UGT1A1; UDP glucuronosyltransferase family 1 member A1; UGT1A3; UDP glucuronosyltransferase family 1 member A3 UGT1A6 UDP glucuronosyltransferase family 1 me
The lncRNA SNHG3 regulates energy metabolism of ovarian cancer by an analysis of mitochondrial proteomes
Keywords: Ovarian cancer; Energy metabolism; SNHG3; iTRAQ; TCGA;
A combined literature and in silico analysis enlightens the role of the NDRG family in the gut
Keywords: Biomarkers; Colorectal cancer; Intestinal tract; N-myc downstream-regulated gene; Tumor suppressors; BDM1; Brain developmental-related molecule 1; Cav-1; Caveolin-1; CRC; Colorectal cancer; DAC; 5-aza-2'-deoxycytine; DFS; Disease free survival; EMT; Epi
Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice
Keywords: Tumor Progression; Immune Cell Migration; Anti-tumor Immune Response; Infiltration; ChIP; chromatin immunoprecipitation; CM; conditioned medium; HUVEC; human umbilical vein endothelial cell; IHC; immunohistochemistry; MLC; monocyte lineage cell; MVD; micr
Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis
Keywords: miRNAs; Urologic cancer; Prognosis; Biomarker; Bioinformatics analysis; miRNA panel; RNA; ribonucleic acid; miRNA; microRNA; KCa; kidney cancer; BCa; bladder cancer; PCa; prostate cancer; TCGA; The Cancer Genome Atlas; OS; overall survival; PSA; prostate
Overexpression of G-protein-coupled receptors 65 in glioblastoma predicts poor patient prognosis
Keywords: Glioblastoma; GPR65; Prognosis; TCGA;
Integrative analysis of CXCR4/CXCL12 axis gene expression alterations in breast cancer and its prognostic relevance
Keywords: CXCR4; C-X-C chemokine receptor type 4; CXCL12; C-X-C Motif Chemokine Ligand 12; EMT; Epithelial-Mesenchymal transition; SDF1; Stromal cell-derived factor 1; KMPLOTTER; Kaplan-Meier plotter; TCGA; The Cancer Genome Atlas; CXCR4; Breast cancer; Invasion;
Role of miR-452-5p in the tumorigenesis of prostate cancer: A study based on the Cancer Genome Atl(TCGA), Gene Expression Omnibus (GEO), and bioinformatics analysis
Keywords: Bioinformatics analysis; GEO; miR-452-5p; Prostate cancer; Target gene; TCGA;
Current insight into a cancer-implicated long noncoding RNA ZFAS1 and correlative functional mechanisms involved
Keywords: HGP; human genome project; snoRNA; small nucleolar RNA; WGS; whole-genome sequencing; ORF; open reading frame; qRT-PCR; quantitative Real-Time PCR; HCC; hepatocellular carcinoma; CRC; colorectal cancer; EMT; epithelial-mesenchymal transition; GC; gastric
MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer
Keywords: BC; bladder cancer; TCGA; The Cancer Genome Atlas; qRT-PCR; quantitative reverse transcription polymerase chain reaction; CCK8; Cell Counting Kit-8; Annexin V-FITC/PI; Annexin V-fluorescein isothiocyanate/propidium iodide; AKT; protein kinase B; siRNA; sm
Elevated DSN1 expression is associated with poor survival in patients with hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; DSN1; dosage suppressor of Nnf1; ANLTs; adjacent normal liver tissues; OS; overall survival; DFS; disease-free survival; GEO; Gene Expression Omnibus; TCGA; The Cancer Genome Atlas; GEPIA; Gene Expression Profiling Interacti
Prognostic Value of PD-L1 mRNA Sequencing Expression Profile in Non-Small Cell Lung Cancer
Keywords: CCLE; Cancer Cell Line Encyclopedia; GTEx; Genotype-Tissue Expression; HR; hazard ratio; IHC; immunohistochemical; NSCLC; non-small cell lung cancer; PD-1; programmed cell death protein one; PD-L1; programmed cell death protein ligand 1; OS; overall survi
Selective Cytotoxicity of the NAMPT Inhibitor FK866 Toward Gastric Cancer Cells With Markers of the Epithelial-Mesenchymal Transition, Due to Loss of NAPRT
Keywords: Stomach Cancer; Drug Screen; Partial Epithelial-to-Mesenchymal Transition; Synthetic Lethal; ACRG; Asian Cancer Research Group; EMT; epithelial-to-mesenchymal transition; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransfera
MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway
Keywords: GC; Gastric cancer; FAT4; Protocadherin Fat 4; LATS2; Large tumor suppressors 2; CDX2; Caudal-related homeobox transcription factor; FOXM1; Fork head box M1; CTGF; Connective tissue growth factor; CYR61; Cysteine-rich angiogenic inducer 61; RUNX3; Runt-re
Overexpression of signal sequence receptor γ predicts poor survival in patients with hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; SSR; signal sequence receptor; ER; endoplasmic reticulum; ANLT; adjacent normal liver tissue; TCGA; The Cancer Genome Atlas; GEPIA; Gene Expression Profiling Interactive Analysis; qRT-PCR; quantitative real-time polymerase c
MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma
Keywords: c-Myc/EZH2 double positive; microRNA-26a; Epigenetics modification; Metastasis; Advanced hepatocellular carcinoma; AAV; adeno-associated virus; CDK8; cyclin dependent kinase 8; CTDSP2; CTD small phosphatase 2; DEN; diethylnitrosamine; DZNep; 3-deazaneplan
The rs2609255 polymorphism in the FAM13A gene is reproducibly associated with silicosis susceptibility in a Chinese population
Keywords: GWAS; genome-wide association studies; NGS; next-generation sequencing; SNPs; single nucleotide polymorphisms; IIPs; idiopathic interstitial pneumonias; FAM13A; family with sequence similarity 13, member A; IPF; idiopathic pulmonary fibrosis; COPD; chroni
MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species
Keywords: ATT; adjacent tumor tissues; CDDP; cisplatin; MAFG; musculoaponeurotic fibrosarcoma oncogene family, protein G; miR-7; microRNA-7; NSCLC; non-small-cell lung cancer; qMSP; quantitative methylation-specific PCR; qRT-PCR; quantitative real-time PCR; ROS;
Whole-Exome Sequencing of Acquired Nevi Identifies Mechanisms for Development and Maintenance of Benign Neoplasms
Keywords: CNA; copy number aberration; LOH; loss of heterozygosity; SNV; single-nucleotide variants; TCGA; The Cancer Genome Atlas;
Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity
Keywords: Kynurenine; Gastritis; SPEM; Humoral Immunity; EBV; Epstein-Barr virus; FACS; fluorescence-activated cell sorting; IDO1; indoleamine-2,3-dioxygenase-1; IFN; interferon; MDSC; myeloid-derived suppressor cell; mRNA; messenger RNA; NK; natural killer; PE; ph
MiR-1275 promotes cell migration, invasion and proliferation in squamous cell carcinoma of head and neck via up-regulating IGF-1R and CCR7
Keywords: SCCHN; Squamous cell carcinoma of head and neck; IGF-1R; insulin like growth factor 1 receptor; CCR7; C-C chemokine receptor type 7; cDNA; DNA complementary to RNA; UTR; untranslated region(s); TCGA; The Cancer Genome Atlas database; RT-PCR; Real-time pol
EGFR and Ras regulate DDX59 during lung cancer development
Keywords: EGFR; Epidermal growth factor receptor; MAP kinase; Mitogen-activated protein kinase; NSCLC; non-small cell lung cancer; EGFR-TKI; Epidermal growth factor receptor-tyrosine kinase inhibitor; TCGA; The cancer genome atlas; DMEM; Dulbecco's modified essenti
Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer
Keywords: FXR; Obeticholic Acid; S-Adenosylmethionine; Ursodeoxycholic Acid; AP-1; activator protein-1; ARE; antioxidant response element; BDL; bile duct ligation; BrdU; 5-bromo-2'deoxyuridine; CCA; cholangiocarcinoma; FXR; farnesoid X receptor; GSH; reduced glut
The C/EBPβ-LINC01133 axis promotes cell proliferation in pancreatic ductal adenocarcinoma through upregulation of CCNG1
Keywords: LINC01133; CCAAT/enhancer-binding protein β; Cyclin G1; Pancreatic ductal adenocarcinoma; PDAC prognostic biomarker; LncRNAs; Long non-coding RNAs; PDAC; pancreatic ductal adenocarcinoma; C/EBPβ; CCAAT/enhancer-binding protein β; CCNG1; cyclin protein
Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis
Keywords: Binucleated Cells; Large Tumor Suppressor Kinase; Pan-overexpressed; TEA Domain Transcription Factor; AURKB; aurora B kinase; ChIP; chromatin immunoprecipitation; CIN; chromosomal instability; CNL; noncancerous tissue; ECT2; epithelial cell transforming 2
Role of upregulated miR-136-5p in lung adenocarcinoma: A study of 1242 samples utilizing bioinformatics analysis
Keywords: NSCLC; non small cell lung cancer; SCLC; small cell lung cancer; LUAD; lung adenocarcinoma; miRNAs; microRNAs; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; PANTHER; Protein Analysis Through Evolutionary Relationships; GEO; Gene Expres
PSMD2 regulates breast cancer cell proliferation and cell cycle progression by modulating p21 and p27 proteasomal degradation
Keywords: Breast cancer; Ubiquitin-proteasome system; PSMD2; Cell cycle; p21; p27; BC; breast cancer; CI; confidence interval; DMFS; distant-metastasis-free survival; DUBs; deubiquitinating enzymes; E1s; Ub-activating enzymes; E2s; Ub-conjugating enzymes; E3s; Ub-p