Keywords: Act-D; actinomycin-D; ACTB; actin-b; AD; Alzheimer's disease; AT8; Tau epitope with phosphorylated Ser202/Thr205 residues; CNS; central nervous system; DAPI; 4â²,6-diamidino-2-phenylindole; DFC; dense fibrillar component (of the nucleolus); EDTA; ethylen
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Keywords: cGMP; cyclic guanosine monophosphate; DAPI; (4â²,6-Diamidino-2-Phenylindole, Dihydrochloride); EC; endothelial cell; ECs; endothelial cells; eNOS; endothelial nitric oxide synthase; FBS; fetal bovine serum; FITC; Fluorescein isothiocyanate; HAPE; high-al
Keywords: SCA21; spinocerebellar ataxia type 21; TMEM240; transmembrane protein 240; LAMP2A; lysosome-associated membrane protein 2a; TSG101; tumor susceptibility gene 101; Iba1; ionized calcium-binding adapter molecule 1; GFAP; glial fibrillary acidic protein; LC3
Keywords: ACSL; Acyl-CoA synthetases; ANOVA; analysis of variance; CHP; cumene hydroperoxide; CPT1; carnitine palmitoyltransferase 1; CRAT; carnitine acetyltransferase; DHB; 2,5-dihydroxybenzoic acid; FABP; fatty acid binding protein; FCCP; carbonyl cyanide-4-(trif
Keywords: Corneal endothelium; Barrier function; Actomyosin; Rho GTPase; RhoA; Rho kinase; Thrombin; HCEC; human corneal endothelial cell; GTPase; guanosine triphosphatase; GTP; guanosine triphosphate; ROCK; Rho kinase; MRCK; myotonic dystrophy kinase-related Cdc42
Keywords: Molecular receptors; Nanoprobes; Nanosensors; Nanochips; Drug screening; Nanomaterials; DFC; Drug-facilitated crime; UNODC; United Nations Office on Drugs and Crime; GC/MS; Gas Chromatography/Mass Spectrometry; LC/MS; Liquid Chromatography/MS; HPTLC; High
Keywords: PCI; photochemical internalization; BMP; bis(monoacylglycero)-phosphate; CPP; cell-penetrating peptide; Fl-CPP; fluorophore/cell-penetrating peptide conjugate; LUV; large unilamellar vesicle; NBT; nitro blue tetrazolium; PBS; phosphate buffered saline;
Increased Afterload Augments Sunitinib-Induced Cardiotoxicity in an Engineered Cardiac Microtissue Model
Keywords: afterload; apoptosis; cardiotoxicity; sunitinib; tissue engineering; toxicology; tyrosine kinase inhibitors; 2D; 2-dimensional; 3D; 3-dimensional; AICAR; 5-aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AMPK; adenosine monophosphate-activated protein
Identification of chickpea (Cicer arietinum) in foods using a novel real-time polymerase chain reaction detection method
Keywords: A; absorbance; BLAST; basic local alignment search tool; bp; base pair; BSA; bovine serum albumin; CaNCED; 9-cis-epoxycarotenoid dioxygenase in Cicer arietinum; CDS; coding sequence; Ct; threshold cycle; DNA; deoxyribonucleic acid; EDTA; ethylenediaminete
The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells
Keywords: CubipyOXA; Cancer; Apoptosis; Hsp60; Pro-caspase-3 (pC3); Hsp60/pC3 complex; CubipyOXA; [Cu(3,5-bis(2â²-pyridyl)-1,2,4-oxadiazole)2(H2O)2](ClO4)2; ZnbipyOXA; [Zn(bipyOXA)2(H2O)2]2Â +(ClO4)2; Hsp60; heat shock protein 60; pC3; procaspase-3; NCI-H292; muco
Evaluation of biological properties of 3,3â²,4,4â²-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity
Keywords: Virtual High-Throughput Screening; Hexokinase II; P19 cells; Cytotoxicity; Mitochondrial membrane potential; BDTA; 3,3â²,4,4â²-benzophenonetetracarboxylic dianhydride; ECC; embryonal carcinoma cells; GK; glukokinase; G6P; glucose 6-phosphate; G6PD; gluc
The photodynamic action of pheophorbide a induces cell death through oxidative stress in Leishmania amazonensis
Keywords: AA; antimycin A; CCCP; cyanide m-chlorophenylhydrazone; DAF-FM diacetate; 4-amino-5-methylamino-2â²,7â²-difluoro fluoresceÃn; DMSO; dimethylsulfoxide; DPPP; diphenyl-1-pyrenylphosphine; DTNB; 2,2â²-dinitro-5,5â²-dithiobenzoic acid; FBS; fetal bovine
Neutrophil swarming toward Cryptococcus neoformans is mediated by complement and leukotriene B4
Keywords: Neutrophils; Cryptococcus neoformans; Swarming; Complement; CD11b; LTB4; C3; complement component 3; C5; complement component 5; C5a; complement component 5a; C5aR; complement component 5a receptor; CXCL1; chemokine (C-X-C motif) ligand 1; CXCL2; chemokin
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1
Keywords: 5mC; 5-methylcytosine; MBD; methyl-CpG-binding domain; RMSD; root-mean-square deviation; TAMRA; tetramethylrhodamine; Protein-DNA interaction; CpG methylation; Egr-1; Crystallography; Fluorescence;
Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: Identification of novel peptidic inhibitors
Keywords: FAM; carboxyfluorescein; FP; fluorescence polarization; HBTU; O-(1H-benzotriazol-1-yl)-N,N,Nâ²,Nâ²-tetramethyluronium hexafluorophosphate; HOBt; 1-hydroxy-1H-benzotriazole; MDM2; mouse double minute 2 homolog; MDMX; mouse double minute X homolog; TAMRA;
Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: Implications for epigenetic regulation
Keywords: CD; circular dichroism; FRET; fluorescence resonance energy transfer; PCR; reverse transcription-polymerase chain reaction; RMSD; root mean square deviation; FAM; 6-carboxyfluorescein; TAMRA; tetramethylrhodamine; Cytosine; DNA methylation; Bcl-2; G-quadr
Localization of exogenous DNA to mitochondria in skeletal muscle following hydrodynamic limb vein injection
Keywords: Ch; channel; CLSM; confocal laser scanning microscopy; COX; cytochrome c oxidase; DAPI; 4â², 6-Diamidino-2-phenylindole; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; FISH; fluorescent in situ hybridization; GAPDH; Glyceraldehyde 3-phosphat
Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription
Keywords: CD; circular dichroism; ChIP; chromatin immunoprecipitation; CNBP; cellular nucleic-acid-binding protein; Co-IP; co-immunoprecipitation; EMSA; electrophoretic mobility shift assay; FAM; 6-carboxyfluorescein; FRET; fluorescence resonance energy transfer; N
A HaloTag® method for assessing the retrograde axonal transport of the p75 neurotrophin receptor and other proteins in compartmented cultures of rat sympathetic neurons
Keywords: BDNF; brain derived neurotrophic factor; DMSO; dimethylsulfoxide; HT; HaloTag; NGF; nerve growth factor; PBS; phosphate-buffered saline; p75NTR; p75 neurotrophin receptor; SDS; sodium dodecyl sulfate; PAGE; polyacrylamide gel electrophoresis; TMR; tetrame
Evaluation of intrinsic spectroscopic properties of chromophore assemblies by shielding with cyclohexyl base pairs within a DNA duplex
Keywords: DNA; Tetramethylrhodamine; Cyclohexane; Dye cluster; Quenching
Effects of Oxidative Alcohol Metabolism on the Mitochondrial Permeability Transition Pore and Necrosis in a Mouse Model of Alcoholic Pancreatitis
Keywords: Tissue Damage; Ethanol Toxicity; Cell Death; Exocrine Pancreas; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; ATP; adenosine triphosphate; BAL; blood alcohol level; [Ca2+]i; free cytosolic Ca2+; CCK; cholecystokinin-8; CypD; cyclophilin D; ÎÎ
Application of allele-specific quantitative PCR using genomic DNA to monitor minimal residual disease based on mutant gene levels following allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies: Comparison of mutan
Keywords: MRD; minimal residual disease; HSCT; hematopoietic stem cell transplantation; AS-qPCR; allele-specific quantitative polymerase chain reaction; STR-PCR; short tandem repeat-PCR; AML; acute myelogenous leukemia; MDS; myelodysplastic syndrome; BM; bone marro
Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells
Keywords: AMP; antimicrobial peptide; CEM; CCRF-CEM T lymphoblastoid (human acute lymphoblastic leukemia) cells; SW480; human colon adenocarcinoma; HeLa S3; human cervix carcinoma; HUVEC; human umbilical vein endothelial cells; IEC; rat intestinal epithelial cells;
Fluorescence ratiometric detection of ligand-induced receptor internalization using extracellular coiled-coil tag-probe labeling
Keywords: Endocytosis; Tag-probe labeling; Ratio imaging; Membrane receptor; High-throughput screening; β2AR; the human β2-adrenergic receptor; CHO; Chinese hamster ovary; E3; (EIAALKE)3; E3-β2AR; the E3-tagged human β2 adrenergic receptor; FL; fluorescein; K
L-selectin transmembrane and cytoplasmic domains are monomeric in membranes
Keywords: CAT; chloramphenicol acetyl transferase; CD; circular dichroism; DPC; dodecylphosphocholine; FRET; fluorescence resonance energy transfer; GST; glutathione S-transferase; HFIP; hexafluoroisopropanol; HPLC; high performance liquid chromatography; PSGL-1; P
Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane
Keywords: GPCR; G-protein coupled receptor; cAR1; cAMP receptor 1; TIRFM; Total Internal Reflection Microscopy; FRAP; Fluorescence Recovery after Photobleaching; PH; Pleckstrin Homology; TMR; Tetramethylrhodamine; MSD; Mean Square Displacement; Single-molecule TIRF
Phospholipid membrane-interaction of a peptide from S4 segment of KvAP K+ channel and the influence of the positive charges and an identified heptad repeat in its interaction with a S3 peptide
Keywords: Voltage-gated potassium channels; Voltage-sensing domain; S3 and S4 segments; Interaction of S3 and S4 peptides; Peptide-lipid interaction; Membrane-assembly of peptides; TM; transmembrane; Kv; voltage-gated potassium channel; PBS; phosphate buffer sali
Pain MechanismResearch PaperA cyclic peptide targeted against PSD-95 blocks central sensitization and attenuates thermal hyperalgesia
Keywords: pain; PSD-95; hyperalgesia; WDR; LTP; p38; CCI; chronic constriction injury; PDZ; PSD-95 Discs large, Zona occludens 1; PSD; post-synaptic density protein; PWL; paw withdrawal latencies; TMR; tetramethylrhodamine; TS; tetanic stimulation; WDR; wide dynami
Single-molecule imaging towards precise detection of individual photophysics
Keywords: 81.05.-t; 81.07.-b; 81.16-c; 81.20.-n; 82.37.-j; Single-molecule detection; Non-radiative relaxation; Fluorescence microscopy; Tetramethylrhodamine; Silanization;
Postnatal appearance of 5-HT2A receptors on fast flexor and slow extensor rat motor neurons
Keywords: 5-HT2A receptors; motor neurons; motor control; motor development; tonic activity; plateau potentials; EDL; extensor digitorum longus; PFA; paraformaldehyde; SOL; slowly contracting extensor soleus; TMR; tetramethylrhodamine;
Investigation of a novel artificial antimicrobial peptide by fluorescence correlation spectroscopy: An amphipathic cationic pattern is sufficient for selective binding to bacterial type membranes and antimicrobial activity
Keywords: V4; CVKVQVKVGSGVKVQVKVC; Rho 6G; Rhodamine 6G chloride; TMR; tetramethylrhodamine; R18; octadecyl rhodamine B chloride; LPS; lipo-polysaccharide; FITC-LPS; fluorescein isothiocyanate lipopolysaccharide; PBS; Phosphate buffered saline; PC; Phosphatidylchol
Clustering of mutant mitochondrial DNA copies suggests stem cells are common in human bronchial epithelium
Keywords: mtDNA; mitochondrial DNA; CDGE; constant denaturant gel electrophoresis; CDCE; constant denaturant capillary electrophoresis; TMR; tetramethylrhodamine; Mutational spectra; Mitochondrial DNA; Capillary electrophoresis; Bronchial epithelial cell; Stem cell