دانلود مقالات ISI درباره Tgf-Β + ترجمه فارسی

CD8+ T activation attenuates CD4+ T proliferation through dendritic cells modification

Keywords: 1-MT; 1-methyl-tryptophan; BAL; bronchoalveolar lavage; CFSE; 5(6)-carboxyfluorescein diacetate N-succinimidyl ester; CMFDA; 5-chloromethylfluorescein diacetate; DC; dendritic cell; Far-Red; CELLTRACE(TM) FAR RED DDAO-SE; HE; hematoxylin and eosin; IDO; i

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Macrophages enhance tumor-derived autophagosomes (DRibbles)-induced B cells activation by TLR4/MyD88 and CD40/CD40L

Keywords: WT; wide-type; Mφ; macrophage; BAFF; B cell activating factor; TNF; Tumor Necrosis Factor; DRibbles; tumor-derived autophagosomes; DC; dendritic cell; APC; antigen-presenting cells; TGF-β; transforming growth factor-β; TLRs; Toll-like receptors; BMDM;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Overcoming translational challenges - The delivery of mechanical stimuli in vivo

Keywords: BMP; bone morphogenetic protein; CSBD; critical sized bone defect; ECM; extracellular matrix; FGF; fibroblastic growth factor; HA; hydroxyapatite; hADMSCs; human adipose derived mesenchymal stem cells; BM-hMSCs; human bone marrow derived mesenchymal stem

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Serum concentrations of insulin-like growth factor-1, members of the TGF-beta superfamily and follistatin do not reflect different stages of dynapenia and sarcopenia in elderly women

Keywords: BIA; bioelectric impedance analysis; BMI; body mass index; BMP; bone morphogenic protein; DXA; dual-energy X-ray absorptiometry; EWGSOP; European Working Group on Sarcopenia in Older People; FGF; fibroblast growth factor; GDF-8; growth and differentiation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling

Keywords: Ursolic acid; Osteoclastogenesis; NF-κB; Titanium particle; Osteolysis; AP-1; activator protein-1; BV/TV; bone volume/tissue volume; BMD; bone mineral density; BMC; bone mineral content; BMMs; bone marrow monocytes; CK; cathepsin K; CT; computed tomograp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Regulatory effect of Traditional Chinese Medicinal Formula Zuo-Gui-Wan on the Th17/Treg paradigm in mice with bone loss induced by estrogen deficiency

Keywords: ANOVA; Analysis of variance; BMD; Bone mineral density; CIA; Collagen-induced arthritis; CTLA-4; Cytotoxic T lymphocyte antigen 4; CTx; C-terminal telopeptides of typeΙ collagen; DXA; Dual-energy X-ray; E2; Estradiol; Foxp3; Forkhead box P3; GAPHD; Glyce

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Treatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease

Keywords: Hepatic fibrosis; Cholestatic liver fibrosis; Hepatic stellate cell; Anti-fibrotic treatment; TGF-β pathway; Cthrc1; collagen triple helix repeat containing-1; TGF-β; transforming growth factor-β; CBDL; common bile duct ligation; DDC; 3, 5-diethoxycarb

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF

Keywords: 6-OHDA; 6-Hydroxy-dopamine; BBB; Blood-brain-barrier; CEX; Cation Exchange chromatography; CHO; Chinese Hamster Ovary; DOPAC; Dihydroxyphenylacetic acid; Dopa; 3,4-dihydroxyphenylalanine; DA; Dopamine; ECM; Extracellular matrix; GDNF; Glial cell line-de

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Establishment of a heterotypic 3D culture system to evaluate the interaction of TREG lymphocytes and NK cells with breast cancer

Keywords: 2D; two-dimensional; 3D; three-dimensional; BPCM; basal-phenotype culture model; ER; oestrogen receptor; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; GFRM; growth factor-reduced Matrigel; HER2/neu; human epidermal growth factor recep

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Chondrogenesis of human bone marrow mesenchymal stromal cells in highly porous alginate-foams supplemented with chondroitin sulfate

Keywords: AB; alcian blue; ACI; autologous chondrocyte implantation; Alg; alginate; ATR-FTIR; Attenuated Total Reflection-Fourier Transform Infrared; hBM-MSC; human bone-marrow derived MSC; CSC; cross-linked chondroitin sulfate; CTCF; corrected total cell fluoresce

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of tubular Flcn expression as a mouse model for renal tumor induction

Keywords: BHD; FLCN; gene targeting; kidney cancer; mouse model; mTOR; RCC; TGF-β;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Abnormal development of placenta in HtrA1-deficient mice

Keywords: HtrA1; High temperature requirement A1; TGF-β; Transforming growth factor-beta; FGF; Fibroblast growth factor; HtrA1; Placenta; Preeclampsia; Trophoblast; Maternal artery remodeling;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of activin-A and -B in malignant mesothelioma - Attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth

Keywords: ACVR2; type 2 activin receptor; ALK; activin receptor-like kinase; ERK; extracellular signal-regulated kinase; FST; follistatin; FSTL3; follistatin like 3; JNK; c-Jun N-terminal kinase; TGF-β; transforming growth factor-β; Mesothelioma; Activin; Invasiv

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Tranilast: A review of its therapeutic applications

Keywords: ARH; aryl hydrocarbon receptor; bFGF; basic fibroblast growth factor; cAMP; cyclic AMP; CDK; cyclin-dependent kinase; COX-2; cyclooxsygenase-2; CTGF; connective tissue growth factor; CXCL; CX chemokine ligand; CXCR; CX chemokine receptor; EMT; epithelial-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Sp1 transcription factor: A long-standing target in cancer chemotherapy

Keywords: Anticancer drugs; Prognosis; Sp1; Sp3; Transcription factors; Targeted therapy; AMPKα; AMP-activated protein kinase alpha catalytic subunit; Bcl-2; B cell/lymphoma 2; Bcl-w; member of the Bcl-2 family; Bid; BH3 interacting domain death agonist; CDK; cycl

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

TGF-β/BMP proteins as therapeutic targets in renal fibrosis. Where have we arrived after 25 years of trials and tribulations?

Keywords: Kidney fibrosis; Smad proteins; TGF-β1; Bone morphogenetic proteins; Inhibitors; micro-RNAs; ALK1-6; activin receptor-like kinase 1-6; BAMBI; BMP and activin receptor membrane bound inhibitor; BMP; bone morphogenetic protein; CKD; chronic kidney disease;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Advances in drug delivery systems (DDSs) to release growth factors for wound healing and skin regeneration

Keywords: DDSs; drug delivery systems; GFs; growth factors; US; United States; DFU; diabetic foot ulcer; NOD; non-obese diabetic; STZ; streptozotocin; EGF; epidermal growth factor; PDGF; platelet derived growth factor; bFGF; basic fibroblasts growth factor; TGF-β;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting strategies on miRNA-21 and PDCD4 for glioblastoma

Keywords: GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

Keywords: HA; hydroxyapatite; GAG; glycosaminoglycan; PG; proteoglycan; ECM; extracellular matrix; VEGF; vascular endotelial growth factor; HIF-1α; hypoxia-inducible factor-1 alpha; PDGF; platelet-derived growth factor; IL-1; interleukin 1; TNF; tumor necrosis fac

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

TGF-β superfamily signaling in testis formation and early male germline development

Keywords: ALK; activin receptor-like kinase; BMPs; bone morphogenetic proteins; Co-Smads; common-mediator Smads; FGF; fibroblast growth factor; GDFs; growth differentiation factors; I-Smads; inhibitory Smads; PGCs; primordial germ cells; R-Smads; receptor-regulated

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases

Keywords: PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice

Keywords: Mouse Model; Stress Signaling; Obesity; Inflammation; CDAA; choline-deficient amino acid defined; CHOP; CCAAT/enhancer-binding protein homologous protein; CSAA; choline-supplemented l-amino acid; ER; endosplasmic reticulum; FFD; fast-food diet; HSC; hepat

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Immunolocalization of Smurf1 in Hirano bodies

Keywords: Smurf1; Smad ubiquitination regulatory factor 1; TGF-β; transforming growth factor β; AD; Alzheimer's disease; HBs; Hirano bodies; H&E; hematoxylin and eosin; APP; amyloid precursor protein; jpk; jasplakinolide; FBS; fetal bovine serum; PBS; phosphate-b

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Cytokine Expression in Patients with Bladder Pain Syndrome/Interstitial Cystitis ESSIC Type 3C

Keywords: urinary bladder; cystitis; interstitial; pain; interleukins; cytokines; BPS; bladder pain syndrome; ESSIC; European Society of Study of Interstitial Cystitis; IC; interstitial cystitis; IFN-γ; interferon-γ; IL; interleukin; iNOS; inducible NO synthase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Prenatal diagnosis and molecular cytogenetic characterization of de novo pure partial trisomy 6p associated with microcephaly, craniosynostosis and abnormal maternal serum biochemistry

Keywords: aCGH; array comparative genomic hybridization; NT; nuchal translucency; t; translocation; MoM; multiples of the median; β-hCG; β-human chorionic gonadotrophin; dn; de novo; PAPP-A; pregnancy-associated plasma protein-A; der; derivative chromosome; dup;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Smad3 plays an inhibitory role in phosphate-induced vascular smooth muscle cell calcification

Keywords: TGF-β; Smad3; Vascular calcification; Enpp1; Pyrophosphate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Promising roles of mammalian E2Fs in hepatocellular carcinoma

Keywords: E2Fs; E2F family of transcription factors; HCC; hepatocellular carcinoma; pRb; retinoblastoma protein; CDK; cyclin dependent kinase; DBD; DNA binding domain; DP; dimerization partner; LZ; leuzine zipper; MB; marked box; NLS; nuclear localization signal; C

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition

Keywords: TGF-β; ROS; TXN2; HMGA2; Fibronectin; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Reversine increases the plasticity of lineage-committed preadipocytes to osteogenesis by inhibiting adipogenesis through induction of TGF-β pathway in vitro

Keywords: Reversine; 3T3-L1; Preadipocytes; Adipogenesis; Osteogenesis; TGF-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Shedding of epithin/PRSS14 is induced by TGF-β and mediated by tumor necrosis factor-α converting enzyme

Keywords: Epithin; Ectodomain shedding; TGF-β; Tumor necrosis factor-α converting enzyme (TACE);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DNA vaccine encoding HPV-16 E7 with mutation in L-Y-C-Y-E pRb-binding motif induces potent anti-tumor responses in mice

Keywords: HPV; human papilloma virus; PHA; phytohemaglotinin; APC; antigen-presenting cell; CTL; cytolytic T lymphocyte; Rb; retinoblastoma; IFN-γ; interferon γ; IL-4; interleukin 4; TNF; tumor necrosis factor; TGF-β; transforming growth factor beta; PVDF; polyv

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Melatonin counteracts BMP-6 regulation of steroidogenesis by rat granulosa cells

Keywords: ALK; activin receptor-like kinase; ActRI; activin type-I receptor; ActRII; activin type-II receptor; BMP; bone morphogenetic protein; BMPRI; BMP type-I receptor; BMPRII; BMP type-II receptor; FSH; follicle-stimulating hormone; FSHR; FSH receptor; GDF; gro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The Notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activation

Keywords: Kidney fibrosis; Epithelial-to-mesenchymal transition; Fibroblast; Notch; TGF-β; DBZ; dibenzazepine; UUO; unilateral ureteral obstruction; NICD; Notch intracellular domain; ICN; intracellular domain of Notch; TECs; tubular epithelial cells; ECM; extracel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Physical exercise protects myenteric neurons and reduces parasitemia in Trypanosoma cruzi infection

Keywords: Physical training; Trypanosoma cruzi; Parasitemia; Nitrergic neuron; TNF-α; TGF-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of TGF-β1 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cells

Keywords: Synovium-derived mesenchymal stem cell; TGF-β; Chondrogenic differentiation; Proliferation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pathological changes in the COPD lung mesenchyme - Novel lessons learned from in vitro and in vivo studies

Keywords: Chronic obstructive pulmonary disease; Inflammation; Extra cellular matrix; Epithelial-mesenchymal interactions; Novel pharmacological targets; CSE; cigarette smoke extract; COPD; chronic obstructive pulmonary disease; EMT; epithelial-mesenchymal tran

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells

Keywords: Osthole; Migration; Invasion; TGF-β; Smad; Akt;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The differential proliferative response of fetal and adult human skin fibroblasts to TGF-β is retained when cultured in the presence of fibronectin or collagen

Keywords: TGF-β; Human skin fibroblast; Fetal; Adult; Fibronectin; Collagen gel; Proliferation; Smad; ERK; PKA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Epidermal growth factor inhibits transforming growth factor-β-induced fibrogenic differentiation marker expression through ERK activation

Keywords: TGF-β; EGF; EMT; Fibrosis; ERK; Smad2/3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of intimal hyperplasia in murine aortic allografts by the oral administration of the transforming growth factor-beta receptor I kinase inhibitor SD-208

Keywords: TGF-β; intimal hyperplasia; transplant arteriosclerosis; TGF-β receptor I kinase inhibitor; Smad3; connective tissue growth factor; smooth muscle-like cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8

Keywords: Osteoarthritis; Wnt signaling; TGF-β; Smad signaling; Chondrocyte hypertrophy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells

Keywords: TGF-β; BAMBI; Porcine; FSH; Luteinizing granulosa cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The Angiotensin II type 1 receptor blocker candesartan suppresses proliferation and fibrosis in gastric cancer

Keywords: Angiotensin II; Gastric cancer; Fibrosis; TGF-β; Peritoneal dissemination;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

An in vitro retinoblastoma human triple culture model of angiogenesis: A modulatory effect of TGF-β

Keywords: Retinoblastoma; Human retinal microvascular endothelial cells; Human retinal microvascular pericytes; TGF-β; Cytosolic and calcium-independent PLA2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Th17 cells and related cytokines in unexplained recurrent spontaneous miscarriage at the implantation window

Keywords: IL-17; IL-21; IL-23; IL-6; TGF-β; unexplained recurrent spontaneous miscarriage;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure

Keywords: bGH; bovine growth hormone; CTRL; control; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GH; growth hormone; GHR; growth hormone receptor; IGF-I; insulin-like growth factor-I; IGF-IR; insulin-like growth factor-I receptor; RPLP0; ribosomal protein larg

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages

Keywords: SAA; serum amyloid A; H3K27me3; trimethylation of histone H3 at lysine 27; HDACs; histone deacetylases; FPR2; formyl peptide receptor 2; G-CSF; granulocyte colony-stimulating factor; IL-23p19; interleukin-23 alpha subunit p19; IL-12p40; interleukin-12 p40

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type I receptor kinase

Keywords: TGF-β; ALK5 inhibitor; Fibrosis; Cancer; Kinase assay; Cell-based luciferase reporter assay; Docking;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه