Helminth mediated modulation of Type 1 diabetes (T1D)
Keywords: Type 1 diabetes; Helminth; NKT; Regulatory T cells; IL-10; TGF-β;
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New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery
Keywords: miRNAs; small non-coding RNAs; HSC; hepatic stellate cell; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; FGF; fibroblast growth factor; ICAM-1; intercellular adhesio
Nemo-like kinase, a multifaceted cell signaling regulator
Keywords: NLK; Nemo-like kinase; IL-6; intereukin-6; MAPK; mitogen activated protein kinase; ERK; extracellular-signal regulated kinase; Pro; proline; Ser; serine; Thr; threonine; C. elegans; Caenorhabditis elegans; POP-1; Posterior pharynx defect protein 1; LEF1;
TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells
Keywords: TGF-β; transforming growth factor-β; IGF; insulin-like growth factor; IGFBP-3; IGF binding protein-3; TβR; TGF-β receptor; IGF1R; type I IGF receptor; TβRII; TGF-β type II receptor; TβRI; TGF-β type I receptor; R-Smads; receptor-activated Smads; M
ATP and UTP stimulate bone morphogenetic protein-2,-4 and -5 gene expression and mineralization by rat primary osteoblasts involving PI3K/AKT pathway
Keywords: ATP; adenosine-5â²-triphosphate; ATPγS; adenosine-5â²-O-(thiotriphosphate); ADP; adenosine-5â²-diphosphate); ADPβS; adenosine-5â²-O-(2-thiodiphosphate); BMPs; bone morphogenetic proteins; UTP; uridine-5â²-triphosphate; ALP; alkaline phosphatase; PI
Constrained selected reaction monitoring: Quantification of selected post-translational modifications and protein isoforms
Keywords: PTM; post-translational modification; MS; mass spectrometry; Erk 1; extracellular-signal-regulated kinase 1; NRGR; neurogranin; TGF-β; transforming growth factor beta; S/N; signal-to-noise ratio; IP; immunoprecipitation; Quantification; Selected reaction
Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis
Keywords: α-Sma; smooth muscle-α-actin; BHLHB2; basic helix-loop-helix domain containing class B2; COL1A1; collagen, type I, alpha 1; COL1A2; collagen, type I, alpha 2; CYP7A1; cytochrome P450 Family 7 Subfamily A Polypeptide 1; DMEM; Dulbecco's modified eagleâ
Regulation of brown adipogenesis by the Tgf-β family: Involvement of Srebp1c in Tgf-β- and Activin-induced inhibition of adipogenesis
Keywords: Brown adipocyte; Tgf-β family; Tgf-β; Activin; Bmp;
Differential induction of IL-17, IL-10, and IL-9 in human T helper cells by B7h and B7.1
Keywords: TH; T helper; APC; antigen-presenting cells; TCR; T cell receptor; mAbs; monoclonal antibody; PBMC; peripheral blood mononuclear cells; ICOS; inducible costimulator; TGF-β; transforming growth factor-β; IL-; interleukine-; INF-γ; interferon-γ; PB; per
Immune following suppression mesenchymal stem cell transplantation in the ischemic brain is mediated by TGF-β
Keywords: Stroke; Inflammation; Microglia; Cell death; Mesenchymal stem cell; TGF-β;
Detection of TCD4+ subsets in human carotid atheroma
Keywords: IFN-γ; interferon-gamma; IL; interleukin; TH; T helper cell; T-bet; T-box expressed in T cells; TNF-α; tumor necrosis factor-α; GATA-3; GATA binding protein 3; Rorγt; related orphan receptor-γt; TGF-β; transforming growth factor beta; CCL20; CC che
Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis
Keywords: extracellular matrix; obstructive nephropathy; renal fibrosis; TGF-β;
The proto-oncogene c-Fos transcriptionally regulates VEGF production during peritoneal inflammation
Keywords: c-Fos; mesothelial cells; peritoneal dialysis; peritonitis; TGF-β; VEGF;
Activation of invariant natural killer T cells by α-galactosylceramide ameliorates myocardial ischemia/reperfusion injury in mice
Keywords: AAR; area at risk; αGC; α-galactosylceramide; IFN-γ; interferon-γ; IL; interleukin; iNKT; invariant natural killer T; I/R; ischemia/reperfusion; IS; infarct size; LV; left ventricle; MI; myocardial infarction; MNCs; mononuclear cells; MPO; myeloperoxi
Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway
Keywords: PRP; platelet rich plasma; PRF; platelet rich fibrin; VEGF; vascular endothelial growth factor; PD-EGF; platelet-derived epidermal growth factor; PDGF; platelet-derived growth factor; b-FGF; basic fibroblast growth factor; Ang; angiopoietin; TGF-β; trans
β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy
Keywords: FAK; focal adhesion kinase; PKA; protein kinase A; BAD; BCL2-associated death protein; VEGF; vascular endothelial growth factor; PlGF; placenta-derived growth factor; PDGF; platelet-derived growth factor; TGF-β; transforming growth factor β; HIF-1α; hy
Interaction between non-small-cell lung cancer cells and fibroblasts via enhancement of TGF-β signaling by IL-6
Keywords: Non-small-cell lung cancer; Fibroblasts; Epithelial-mesenchymal transition; IL-6; TGF-β;
Ubiquitin C-terminal hydrolase-L5 is required for high glucose-induced transforming growth factor-β receptor I expression and hypertrophy in mesangial cells
Keywords: UCHL5; Ubiquitination; High glucose; Mesangial cells; TGF-β;
MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31
Keywords: 3â²UTR; 3â² untranslated region; ALP; Alkaline phosphatase; AP-1; Activator protein 1; ATF4; Activating transcription factor 4; BGLAP; Bone gamma-carboxyglutamate (gla) protein; BMP; Bone morphogenetic protein; COL1A1; Collagen, type I, alpha 1; FBS; Fe
Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: Potential therapeutic targets for cardiac cachexia
Keywords: Ang II; angiotensin II; AT1R; angiotensin II type 1 receptor; CHF; congestive heart failure; ESRD; end-stage renal disease; ACE; angiotensin-converting enzyme; UPS; ubiquitin proteasome system; ROS; reactive oxygen species; IGF-1; insulin-like growth fact
Protective effects of tocotrienols against lipid-induced nephropathy in experimental type-2 diabetic rats by modulation in TGF-β expression
Keywords: Tocotrienols; Tocotrienol rich fraction; Diabetic nephropathy; TGF-β; Fibronectin;
Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition
Keywords: 2-DG; 2-deoxy-D-glucose; 2-DG6P; 2-deoxy-d-glucose-6-phosphate; AHR; aryl hydrocarbon receptor; Arg1; arginase 1; ARNT; AHR nuclear translocator; bFGF; basic fibroblast growth factor; CAF; cancer associated fibroblast; CCL5; C-C chemokine ligand 5; CSF-1;
Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors
Keywords: TDGF-1; teratocarcinoma-derived growth factor-1; CFC; Cripto-1/FRL1/Cryptic; GPI; glycosylphosphatidylinositol; TGF-β; transforming growth factor-β; GDF; growth differentiation factor; Tcf; T-cell factor; Fz; frizzled; LRP; low-density lipoprotein recep
Thioredoxin inhibits MPK38-induced ASK1, TGFâβ, and p53 function in a phosphorylation-dependent manner
Keywords: MPK38/MELK; Trx; ASK1; TGF-β; p53; Free radicals;
Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts
Keywords: ALP; alkaline phosphatase; BGJ medium; Biggers, Gwatkin, and Judah medium; BMP; bone morphogenetic protein; β-TrCP; β-transducin repeat-containing protein; Col1a1; type I collagen 1a1; CTGF; connective-tissue growth factor; CREB; cAMP responsive element
Nox4 and diabetic nephropathy: With a friend like this, who needs enemies?
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; AGE; advanced glycation end-product; Akt/PKB; Akt/protein kinase B; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; AOPP; advanced oxidation protein product; AT1; angiotensin II t
Differential response of epithelial stem cell populations in hair follicles to TGF-β signaling
Keywords: TGF-β; Hair follicle stem cells; Isthmus; Bulge; Hair cycle; Mouse;
Transforming growth factor-β1b: A second TGF-β1 paralogue in the rainbow trout (Oncorhynchus mykiss) that has a lower constitutive expression but is more responsive to immune stimulation
Keywords: Rainbow trout; TGF-β; Macrophage; LPS; VHSV;
Regulatory T cells in atherosclerosis and strategies to induce the endogenous atheroprotective immune response
Keywords: LDL; low density lipoprotein; Tregs; regulatory T cells; IL; interleukin; TGF-β; transforming growth factor beta; Foxp3; forkhead box 3; IL-2R; interleukin-2 receptor; CTLA-4; cytotoxic T-lymphocyte antigen 4; NK; natural killer; DCs; dendritic cells; TC
Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis
Keywords: Colon Cancer; Carcinoma; Signal Transduction; Chemokine; BMDC; bone marrow-derived cell; BMP; bone morphogenetic proteins; CRC; colorectal cancer; DFS; disease-free survival; mCCL9; mouse CCL9; MMP; matrix metalloproteinase; mRNA; messenger RNA; SBE; Smad
Different modifications of phosphorylated Smad3C and Smad3L through TGF-β after spinal cord injury in mice
Keywords: Interleukin-6; Phosphorylation; Smad3; Spinal cord injury; TGF-β;
Losartan Added to β-Blockade Therapy for Aortic Root Dilation in Marfan Syndrome: A Randomized, Open-Label Pilot Study
Keywords: ARB; angiotensin II receptor blockade; AT1; angiotensin II type 1; BB; β-blockade; BB-L; BB and losartan; MFS; Marfan syndrome; TGF-β; transforming growth factor β;
Matrix metalloprotease 9 promotes liver recovery from ischemia and reperfusion injury
Keywords: MMP-9; TGF-β; Ischemia and reperfusion injury; Hepatic stellate cells;
Involvement of bone morphogenetic protein activity in somatostatin actions on ovarian steroidogenesis
Keywords: ALK; activin receptor-like kinase; ActRI; activin type-I receptor; ActRII; activin type-II receptor; BMP; bone morphogenetic protein; BMPRI; BMP type-I receptor; BMPRII; BMP type-II receptor; FSH; follicle-stimulating hormone; FSHR; FSH receptor; FSK; for
Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-β signaling and perturbation of MAPK signaling
Keywords: PDGFB; Ha-Ras(G12V); EGR4; TGF-β; Myofibroblast; FOXG1; Microarrays;
La maladie de Lapeyronie
Keywords: Maladie de Lapeyronie; Dysfonction érectile; Courbure du pénis; TGF-β; Chirurgie du pénis; Nesbit; Yachia; Implants péniens; Lapeyronie's disease; Erectile dysfunction; Penile curvature; TGF-β; Medical penile surgery; Penile plicature; Nesbit; Yachi
Nucleotide sequencing and DNA polymorphism studies of BMP 15 gene in Corriedale and local Kashmir valley sheep (Ovis aries)
Keywords: BMP 15; Bone morphogenetic protein 15; BMPR1B; Bone morphogenetic protein receptor type IB; Fec X; Fecundity X; GDF 9; Growth differentiation factor 9; PCR; Polymerase chain reaction; SSCP; Single strand conformation polymorphism; SNP; Single nucleotide p
The potential of microRNAs in liver fibrosis
Keywords: miRNA; microRNA; ECM; extracellular matrix; HSC; hepatic stellate cell; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; 3'UTR; 3'untranslated region; PDGF; platelet-derived growth factor; HCC; hepatocellular carcinoma; ACSL1; acyl-C
Negative regulation of Odd-skipped related 2 by TGF-beta achieves the induction of cellular migration and the arrest of cell cycle
Keywords: TGF-β; transforming growth factor-beta; Osr2; Odd-skipped related 2; CRE; cAMP response element; EMT; epithelial-mesenchymal transition; Transcription factor; Odd-skipped related 2; Transforming growth factor-beta; Cellular migration; Promoter;
Interleukin-17 producing T helper cells are increased during natural Plasmodium vivax infection
Keywords: Plasmodium vivax; Th17; TNF-α; TGF-β; IL-10;
Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression
Keywords: ARBs; Angiotensin II type 1 receptor blockers; TAC; transverse aortic constriction; AF; atrial fibrillation; EMT; Epithelial-to-mesenchymal transition; MMPs; matrix metalloproteinases; LVAWD and LVPWD; left ventricular anterior and posterior wall at end-d
Role of Smad phosphatases in BMP-Smad signaling axis-induced osteoblast differentiation
Keywords: BMPs; bone morphogenetic proteins; TGF-β; transforming growth factor-β; Smurf1; Smad ubiquitination regulatory factor 1; MAPKs; mitogen-activated protein kinases; Osx; Osterix; SCPs; small C-terminal domain phosphatases; PPM1A; protein phosphatase magne
The burning question: Why is smoking a risk factor for pancreatic cancer?
Keywords: Smoking; Pancreatic cancer; Fibrosis; Inflammation; cAMP; cyclic AMP; EGFR; epidermal growth factor receptor; ECM; extracellular matrix protein; IL-1β; interleukin 1 beta; MIP-1α; macrophage inflammatory protein 1 alpha; MMPs; matrix metalloproteinases;
Transforming growth factor β and apoptosis in leprosy skin lesions: possible relationship with the control of the tissue immune response in the Mycobacterium leprae infection
Keywords: Leprosy; TGF-β; Apoptosis; Cytokines; Immunopathology; Mycobacterium leprae;
BMP action in the pituitary: Its possible role in modulating somatostatin sensitivity in pituitary tumor cells
Keywords: ActRI and ActRII; activin type I and type II receptors; ALK; activin receptor-like kinase; BMP; bone morphogenetic protein; BRC; bromocriptine; BMPRI and BMPRII; BMP type I and type II receptors; DA; dopamine agonists; D2R; dopamine D2 receptor; FSK; fors
TGF-β induced by interleukin-34-stimulated microglia regulates microglial proliferation and attenuates oligomeric amyloid β neurotoxicity
Keywords: TGF-β; IL-34; Microglia; Neuroprotection; Oligomeric amyloid β;
Inhibition of erythropoiesis by Smad6 in human cord blood hematopoietic stem cells
Keywords: BMPs; bone morphogenetic proteins; TGF-β; transforming growth factor-β; I-Smad; inhibitory Smad; HSCs; hematopoietic stem cells; BMPRI; BMP type I receptor; R-Smads; receptor-regulated Smads; KLF1/EKLF; Kruppel-like factor 1 (erythroid); GATA; GATA bind
c-Jun N-terminal kinase controls a negative loop in the regulation of glial fibrillary acidic protein expression by retinoic acid
Keywords: GFAP; c-Jun N-terminal kinase; retinoic acid; neural precursor cells; BMP-2; bone morphogenetic protein-2; DNA-PKcs; DNA-protein kinase catalytic subunit; ERK; extracelular-regulated kinase; GFAP; glial fibrillary acidic protein; GSK-β; glycogen synthase
Protective immunization of hamsters against Opisthorchis viverrini infection is associated with the reduction of TGF-β expression
Keywords: Opisthorchis viverrini; Hamster; IL-10; IL-4; TGF-β; IFN-γ;
Measurement of human latent transforming growth factor-β1 using a latency associated protein-reactive ELISA
Keywords: FBS; fetal bovine serum; GFP; Green fluorescent protein; LAP; Latency associated protein; LTBP; Latent TGF-β binding protein; mAb; monoclonal antibody; PBMC; peripheral blood mononuclear cells; PBS; phosphate-buffered saline; rh; recombinant human; TGF-Î