Keywords: Saliva; Obesity; Oral health; Cytokines; Biomarkers; API; approximal plaque index; AUC; area under the curve; BMI; body mass index; CAL; clinical attachment level; CRP; C-reactive protein; DMF-S; caries prevalence index (decayed, missing, and filled surfa
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Keywords: Aml; amlodipine; Ca2+; free calcium; DHP; dihydropyridine; Dil; diltiazem; Epo; erythropoietin; EpoR; erythropoietin receptor; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; PBS; phosphate-buffered saline; Pyr3; TRPC3 inhibitor;
Keywords: Diabetic kidney disease; Biomarkers; Progression; TNFR1; Leptin-adiponectin ratio; C-reactive protein;
Keywords: NSAIDs; Non-steroidal anti-inflammatory drugs; COX; Cyclooxygenase; PGs; prostaglandins; AA; arachidonic acid; LO; lipoxygenase; Tx; thromboxanes; CNS; central nervous system; EP4R; Prostaglandin E2 receptor 4; PKA; Protein kinase A; PKC; Protein kinase C
Keywords: B2M; β2 microglobulin; DC; dendritic cell; IL; interleukin; LPS; lipopolysaccharide; LT; lymphotoxin; mAb; monoclonal antibody; MZ; marginal zone; Nod1; nod-containing protein 1; PALS; periarteriolar lymphoid sheath; PAMP; pathogen-associated molecular p
Keywords: Plasma biomarker; Idiopathic pneumonia syndrome; Viral pneumonia; ST2; IL-6; TNFR1;
Keywords: AIDS; acquired immuno deficiency syndrome; ATP; adenosine triphosphate; AOC; alteration of consciousness; AQP4; aquaporin 4; Kv.4.2; A-type voltage-gated potassium channel; bFGF; basic fibroblast growth factor; BBB; blood brain barrier; BM; bone marrow; B
Keywords: Atherosclerosis; Kidney disease; Inflammation; Albuminuria; TNFR1; tumor necrosis factor alpha receptor type 1; eGFR; estimated glomerular filtration rate; CKD; chronic kidney disease; ACR; albumin to creatinine ratio;
Keywords: Schizophrenia; Inflammation; Biomarker; TNFR1; Adiponectin; Pigment epithelium-derived factor; TNF-α; tumor necrosis factor-α; TNFR1; TNF receptor 1; TNFR2; TNF receptor 2; mTNF; membrane-bound TNF-α; sTNF; soluble TNF-α; TACE; TNF-α converting enzym
Keywords: ALS; Amyotrophic lateral sclerosis; Bcl; 2 B-cell lymphoma-2; COX-2; cyclooxygenase-2; DHYZ; DihuangYinziFang; DPPH; 2,2-diphenyl-1-picrylhydrazyl; FALS; familial Amyotrophic lateral sclerosis; FasL; Fas ligand; FDA; Food and Drug Administration; IFN; Int
Keywords: NF-κB; nuclear factor kappa-light chain enhancement of activated B cell; NLR; (Nod)-like receptor; NLRP 3; (Nod)-like receptor pyrin domain containing 3 inflammasome; IL-1α; interleukin-1-alpha; IL-1β; interleukin-1-beta; IL-4; interleukin-4; IL-6; int
Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; Bax; BCL2-associated X protein; Bcl-xL; B-cell lymphoma-extra large; CLP; cecal ligation and puncture; CyP; cyclophilin; DAMP; damage-associated molecular patte
Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; SNpc; substantia nigra pars compacta; MnSOD; manganese superoxide dismutase; CuSOD; copper superoxide dismutase; NO; nitric oxide; O2â; superoxide anion; ONOOâ; peroxy
Keywords: 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
Keywords: COPD; chronic obstructive pulmonary disease; RS; replicative senescence; SIPS; stress induced premature senescence; OIS; oncogene induced senescence; SASP; senescence associated secretory phenotype; TNF-a; tumor necrosis factor-a; TNFR1; TNFa receptor 1;
Keywords: Proinflammatory cytokines; Schizophrenia; Lymphocytes; IL-1β; IL-6; TNF-α; IL-1R1; IL-1R2; IL-1RA; IL-6R; Gp130; TNFR1; TNFR2;
Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide transporter; ATP; adenine triphosphate; C1QBP; complement component 1Q subcomponent-binding protein; Ca2Â +; calcium; CK; creatine kinase; CsA; cyclosporine A; CYCLE; CYCLosporinE A in reperfused acute m
Keywords: ABCA1; ATP-binding cassette, subfamily A, member 1; ABCG5; ATP-binding cassette, subfamily G, member 5; ACD; anemia of chronic disease; AI; anemia of inflammation; Apo; apolipoprotein; Arg1; arginase-1; Bach1; Btb and Cnc Homology, basic leucine zipper tr
Keywords: AIF; apoptosis-inducing factor; ANT; adenine nucleotide translocase; CsA; cyclosporin A; CYPD; cyclophilin D; ÎÏm; mitochondrial transmembrane potential; Fer-1; ferrostatin-1; MAMP; microbe-associated molecular pattern; MLKL; mixed lineage kinase domain
Keywords: APAP; Acetaminophen; AP-1; Activator protein 1; ASK1; Apoptosis signaling kinase; BMD; Benchmark dose; BMDL; Lower confidence limit of benchmark dose; BrdU; Bromodeoxyuridine; bw; Body weight; JNK1; c-Jun NH2-terminal kinase 1; CT; Carbon tetrachloride; B
Keywords: TNFR1; Gene regulation; Inflammation
Keywords: Severe mental disorders; Inflammation; Immune factors; Psychotic symptoms; tnfr1; IL-1Ra;
TNF activity and T cells
Keywords: TNF; TNFR1; TNFR2; T cells; Treg;
Study of extrinsic apoptotic pathway in oral Lichen Planus using TNFR 1 and FasL immunohistochemical markers and TUNEL technique
Keywords: Lichen planus; Apoptosis; TUNEL technique; TNFR1; FasL;
TNFR signalling and its clinical implications
Keywords: TNF; TNFR1; TNFR2; Autoimmune disease; Anti-TNF-α therapy;
Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway
Keywords: PFOS; Oxidative stress; Hepatotoxicity; NF-κB/TNF-α; ALT; alanine aminotransferase; AST; aspartate transaminase; APAP; acetaminophen; BSA; bovine serum albumin; CAT; catalase; Cyt c; cytochrome c; DCFDA; 2,7-dichlorofluorescein diacetate; DMSO; dimethyl
Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα - activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression
Keywords: EC; endothelial cells; TNFα; tumor necrosis factor α; MCP-1; monocyte chemoattractant protein 1; VCAM-1; vascular cell adhesion molecule 1; Ninj-1; ninjurin-1; ROS; reactive oxygen species; NF-kB; nuclear factor-κB; Nrf2; NF-E2-related factor; HO-1; he
Impaired social behaviors and minimized oxytocin signaling of the adult mice deficient in the N-methyl-d-aspartate receptor GluN3A subunit
Keywords: GluN3A; glutamate NMDA receptor subunit 3A or NR3A; NMDA; N-methyl-d-aspartate; NMDAR; N-methyl-d-aspartate receptor; KO; knockout; WT; wild-type; CNS; central nervous system; ASD; autism spectrum disorders; AVP; vasopressin; 5-HTR; serotonin receptor; 5-
Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats
Keywords: AAV; adeno-associated virus; ACE; angiotensin converting enzyme; AT1R; angiotensin II type 1 receptors; AT1aR; angiotensin II type 1a receptors; AngII; angiotensin II; AVP; arginine vasopressin; BW; body weight; CD68; cluster of differentiation 68; CL; le
Regulation of inflammation by β-arrestins: Not just receptor tales
Keywords: βarr; β-arrestin; IL; interleukin; IκBα; inhibitor α of NFκB; IKK; IκB kinase; MEF; mouse embryo fibroblast; LPA; lysophosphatidic acid; TLR4; Toll-like receptor-4; TNF; tumor necrosis factor; TNFR1; TNF receptor-1; TRAF; TNFR-associated factor; 7T
SOCS-1 ameliorates smoke inhalation-induced acute lung injury through inhibition of ASK-1 activity and DISC formation
Keywords: SOCS-1; suppressor of cytokine signaling-1; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; SAECs; small airway epithelial cells; GFP; green fluorescent protein; SH2; Src homology 2; ASK-1; apoptosis signal-regulating kinase-1; DISC; de
Phenolic acid and flavonoid-rich fraction of Sasa quelpaertensis Nakai leaves prevent alcohol induced fatty liver through AMPK activation
Keywords: ALD; alcohol liver disease; AMPK; AMP-activated protein kinase; BW; body weight; CYP2E1; cytochrome P450 2E1; DPBS; Dulbecco's phosphate-buffered saline; EtOH; ethanol; FAS; fatty acid synthase; GSH; glutathione; H&E; hematoxylin and eosin; HPLC; high p
ROS signalling in the biology of cancer
Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel
Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet
Keywords: High-fat diet; TNFR1; Nonalcoholic liver disease; IL-1 beta; Insulin resistance; Inflammation; IRS1;
Multifunctional molecule ERp57: From cancer to neurodegenerative diseases
Keywords: 1α,25(OH)2D3; 1,25-dihydroxyvitamin D3; ADAM10; a disintegrin and metalloproteinase 10; AIF; apoptosis-inducing factor; AP-1; activator protein 1; ATRA; all-trans retinoic acid; BMP-2; bone morphogenic protein 2; CLNX; calnexin; CRT; calreticulin; ECM; e
Autophagy in ischemic stroke
Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5â²-triphosphate; BBB; blood-brain ba
Research ArticleGreen tea extract treatment reduces NFκB activation in mice with diet-induced nonalcoholic steatohepatitis by lowering TNFR1 and TLR4 expression and ligand availability
Keywords: Green tea; NASH; Inflammation; TNFR1; TLR4; Nonalcoholic steatohepatitis;
Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis
Keywords: CC1; anti-adenomatours polyposis coli clone CC1; CD11b; cluster of differentiation molecule 11B; CFA; complete Freund adjuvant; DHP; dihydroprogesterone; EAE; experimental autoimmune encephalomyelitis; Fis1; mitochondrial fission 1; GABA; gamma-aminobutyr
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium
Keywords: 129; 129S1/SvimJ; B6; C57BL6/J; DKO; double knockout of GPx1 and GPx2 genes; DUOX 2; dual oxidase-2; Duoxa; Duox activator; Duoxa-TKO; triple-knockout mice with disrupted Duoxa, GPx1 and GPx2 genes; DSS; dextran sodium sulfate; DTI; di-2-thienyliodonium;
A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing
Keywords: BCA; bicinchoninic acid; CV; coefficient of variation; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBMCs; peripheral blood mononuclear cells; RPPA; reverse phase protein array; SSMD; strictly standardized mean difference; TNFR1; tum
BH3-only protein BIM: An emerging target in chemotherapy
Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Keywords: Regulated Cell Death; Antitumor Immunity; HMGB1; ATP; AURKA; aurora kinase A; DAMPs; damage-associated molecular patterns; GSK3β; glycogen synthase kinase 3 beta; HEK293; human embryonic kidney 293; HPDE; human pancreatic duct epithelial cell; ICD; immun
The Tag7–Hsp70 cytotoxic complex induces tumor cell necroptosis via permeabilisation of lysosomes and mitochondria
Keywords: Tag7; Hsp70; Necroptosis; TNFR1; Mitochondria; Lysosoma
The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease
Keywords: COX-2; cycoloxygenase-2; DOPAC; 3,4-dihydrophenylacetic acid; FN14; fibroblast growth factor-inducible 14; HPLC; high-performance liquid chromatography; HRP; horseradish peroxidase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NF-κB; nuclear facto
Effect of curcumin on TNFR2 and TRAF2 in unilateral ureteral obstruction in rats
Keywords: Curcumin; TNFR1; TNFR2; TRAF2; Caspase 8; RIP
Biotrauma and Ventilator-Induced Lung Injury
Keywords: biotrauma; critical care; mechanical ventilation; respiratory failure; ventilator-induced injury; AEC; alveolar epithelial cell; CRS; compliance of the respiratory system; ECMO; extracorporeal membrane oxygenation; IL; interleukin; PBW; predicted body wei
Coordinated expression of TNFα- and VEGF-mediated signaling components by placental macrophages in early and late pregnancy
Keywords: Placental macrophages; TNFα; VEGF; TNFR1; VEGFR1;
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
Keywords: Ubiquitin; Innate immunity; TNF; TLR3; NOD1; LUBAC; AMSH-LP; AMSH-like protein; λ-PPase; bacteriophage λ protein phosphatase; BMDM; bone marrow-derived macrophages; JNK; c-Jun N-terminal kinase; cIAP; cellular Inhibitor of Apoptosis; DUB; deubiquitylase
IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligation
Keywords: IinQ; 2-hydroxy-5,6-dihydroisoindolo[1,2-a]isoquinoline-3,8-dione; NF-κB; Nuclear factor-kappa B; IκBα; inhibitory kappa B alpha; TLR; toll like receptor; TNFR1; tumor necrosis factor receptor 1; IKK; IκB kinase; LPS; lipopolysaccharide; MyD88; a myel
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling
Keywords: RIPK1; necroptosis; TNFR1; LUBAC; cIAP1/2; ubiquitination