Keywords: مهار تونیک; Insomnia; Sleep; Epilepsy; Melatonin; Antiepileptic; Tonic inhibition;
مقالات ISI مهار تونیک (ترجمه نشده)
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Keywords: مهار تونیک; EPSC; IPSC; Tonic inhibition; Synaptic inhibition; Synaptic; Excitation;
Keywords: مهار تونیک; Purkinje cells; Stellate cells; Basket cells; Golgi cells; Granule cells; Inhibitory synapses; Tonic inhibition;
Enhanced Activities of δ Subunit-containing GABAA Receptors Blocked Spinal Long-term Potentiation and Attenuated Formalin-induced Spontaneous Pain
Keywords: مهار تونیک; ACSF; artificial cerebrospinal fluid; AMPARs; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptors; EDTA; ethylenediaminetetraacetic acid; GABAARs; γ-Aminobutyric acid type A receptors; HEPES; 4-(2-hydroxyethyl)-1-piperazi
Altered expression of GABA-A receptor subunits in the hippocampus of PTZ-kindled rats
Keywords: مهار تونیک; Seizures; PTZ kindling; GABA-A receptor subunits; Tonic inhibition; Rats;
Huntington's disease leads to decrease of GABA-A tonic subunits in the D2 neostriatal pathway and their relocalization into the synaptic cleft
Keywords: مهار تونیک; Tonic inhibition; Extrasynaptic and perisynaptic GABA-A receptors; Chorea; D2 medium-size spiny neurons; YAC128 mouse model;
Loop F of the GABAA receptor alpha subunit governs GABA potency
Keywords: مهار تونیک; GABA binding-pocket; α5-GABAA-receptors; Tonic inhibition; Object recognition memory; Long-term memory;
Research PaperDecreased surface expression of the δ subunit of the GABAA receptor contributes to reduced tonic inhibition in dentate granule cells in a mouse model of fragile X syndrome
Keywords: مهار تونیک; GABA receptor; Tonic inhibition; Dentate gyrus; Fmr1 gene; Fragile X mental retardation protein; Fragile X syndrome;
Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors
Keywords: مهار تونیک; GABAergic; IPSC; Tonic inhibition; Synaptic inhibition; TB-21007; MRK-016; α5IA; L-655708; GABAAR; GABA type-A receptor; IPSC; inhibitory postsynaptic current; DMEM-FBS; Dulbecco's Modified Eagles Medium supplemented with 10% fetal bovine serum; TB-21007
Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion
Keywords: مهار تونیک; GABAA; Extrasynaptic; Binge drinking; THIP; Females; Mouse; Alcohol; Delta; Tonic inhibition;
Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent
Keywords: مهار تونیک; Tonic inhibition; Phasic inhibition; α5-GABAA receptors; Extrasynaptic GABAA receptors; Long term potentiation; Cognition;
GABAergic regulation of the HPA and HPG axes and the impact of stress on reproductive function
Keywords: مهار تونیک; Neurosteroids; Stress; GABAA receptors; KCC2; GnRH; Estrous; Puberty; LH; Allopregnanolone; THDOC; Tonic inhibition; Extrasynaptic; Gabrd;
Clinical Potential of Neurosteroids for CNS Disorders
Keywords: مهار تونیک; brain injury; epilepsy; GABA-A receptor; neurosteroid; status epilepticus; tonic inhibition
Potentiation of tonic GABAergic inhibition by activation of postsynaptic kainate receptors
Keywords: مهار تونیک; AP-5; D-(â)-2-amino-5-phosphonopentanoic acid; eGABAAR; extrasynaptic GABAA receptor; EGTA; ethylene glycol tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSC; stimulus-evoked inhibitory postsynaptic current; KA; Kainic ac
Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABAA receptor
Keywords: مهار تونیک; Hippocampus; Tonic inhibition; Etomidate; LTP; Learning; GABA receptors;
Molecular aspects of age-related cognitive decline: the role of GABA signaling
Keywords: مهار تونیک; GABAA α5; GABAB receptor; hippocampus; memory; tonic inhibition; prefrontal cortex
Altered expression of δGABAA receptors in health and disease
Keywords: مهار تونیک; δGABAA receptor; Tonic inhibition; Expression; Plasticity; Behavior; Disease; CA1; Cornu Ammonis subfield 1 of the hippocampus; CNS; central nervous system; Fmr1-KO; transgenic mice lacking the Fmr1 gene; FMRP; fragile X mental retardation protein; GABAA
In vitro gamma oscillations following partial and complete ablation of δ subunit-containing GABAA receptors from parvalbumin interneurons
Keywords: مهار تونیک; Gamma oscillations; Tonic inhibition; GABAA receptors pharmacology; Delta subunit; CA3 interneurons; Parvalbumin; Neurosteroids; DS-2;
GABAB receptors in maintenance of neocortical circuit function
Keywords: مهار تونیک; GABAB; Neocortex; Tonic inhibition; MGE;
Loss of Gabrd in CRH neurons blunts the corticosterone response to stress and diminishes stress-related behaviors
Keywords: مهار تونیک; GABA; Tonic inhibition; CRH neurons; Paraventricular nucleus; Hypothalamus; HPA axis; Stress; Corticosterone; Depression; Anxiety
Monoterpene α-thujone exerts a differential inhibitory action on GABAA receptors implicated in phasic and tonic GABAergic inhibition
Keywords: مهار تونیک; Tonic inhibition; Recombinant GABAA receptor; Current response; Rapid application;
Tonic GABAA receptor-mediated signalling in temporal lobe epilepsy
Keywords: مهار تونیک; Tonic inhibition; GABAA receptors; Temporal lobe epilepsy; Hippocampus;
Short CommunicationDopaminergic modulation of tonic but not phasic GABAA-receptor-mediated current in the ventrobasal thalamus of Wistar and GAERS rats
Keywords: مهار تونیک; GABAA receptors; Tonic inhibition; Ventrobasal thalamus; Absence epilepsy; Patch-clamp; Dopamine;
Inhibition of VTA neurons activates the centrally projecting Edinger–Westphal nucleus: Evidence of a stress–reward link?
Keywords: مهار تونیک; Edinger–Westphal nucleus; Urocortin; Stress; Dopamine; Tonic inhibition
Research ReportKnockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty
Keywords: مهار تونیک; Puberty; GABA type A receptor; THP; Tonic inhibition; Alpha 4; Delta; Allopregnanolone;
Sex-specificity of associative learning-induced changes in GABAergic tonic inhibition in layer 4 neurons of mouse barrel cortex
Keywords: مهار تونیک; Brain slices; Classical conditioning; Tonic inhibition; Somatosensory cortex; Sex
GABA transport modulates the ethanol sensitivity of tonic inhibition in the rat dentate gyrus
Keywords: مهار تونیک; Ethanol; GABAA receptor; Tonic inhibition; Extrasynaptic receptors; Dentate gyrus; Adolescence;
ClC-2 contributes to tonic inhibition mediated by α5 subunit-containing GABAA receptor in experimental temporal lobe epilepsy
Keywords: مهار تونیک; ClC-2; temporal lobe epilepsy; hippocampus; tonic inhibition; α5 subunit-containing GABAA receptorClC-2, chloride channel-2; ClC-2 IR, ClC-2 immunoreactivity; Itonic, tonic inhibitory currents; PCs, pyramidal cells; SE, status epilepticus; SRS, spontaneou
Progressive loss of phasic, but not tonic, GABAA receptor-mediated inhibition in dentate granule cells in a model of post-traumatic epilepsy in rats
Keywords: مهار تونیک; dentate gyrus; GABAA receptors; interneurons; parvalbumin; tonic inhibition; traumatic brain injuryDGC, dentate granule cell; IPSC, inhibitory postsynaptic current; KPBS, potassium phosphate buffered saline; mIPSC, miniature IPSC; NHS, normal horse serum;
Trace and contextual fear conditioning is enhanced in mice lacking the α4 subunit of the GABAA receptor
Keywords: مهار تونیک; GABAAR; Trace fear conditioning; Delay fear conditioning; α4; δ; Tonic inhibition; Neurosteroids; Sex difference; Hippocampus
Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals
Keywords: مهار تونیک; Temporal lobe epilepsy; Dentate granule cells; GABA-A receptor; Tonic inhibition; Neurosteroids
GABAA receptors of cerebellar granule cells in culture: explanation of overall insensitivity to ethanol
Keywords: مهار تونیک; subunit composition; furosemide; zinc; tonic inhibition; ethanol sensitivityEGTA, ethylene glycol tetracetic acid; GABA, gamma-aminobutyric acid; Hepes, N-(2-hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) sodium salt; Tris, Tris (hydroxymethyl) aminom
Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant α4β3δ and α4β3 GABAA receptors expressed in HEK cells
Keywords: مهار تونیک; Tonic inhibition; Delta subunit; Etomidate; Propofol; Anesthesia; Neurosteroid THDOC; Alcohol; GABA; γ-aminobutyric acid; GABAAR; type A GABA receptor; HEK; human embryonic kidney; β-CCE; β-carboline-3-carboxyethyl ester; EtOH; ethanol; THDOC; tetrahyd
Function and modulation of δ-containing GABAA receptors
Keywords: مهار تونیک; αβδ GABAA receptors; Tonic inhibition; Tracazolate; Neurosteroids
GABAA receptors in the thalamus: α4 subunit expression and alcohol sensitivity
Keywords: مهار تونیک; Alcohol; Alpha-4 subunit; GABAA receptors; Extrasynaptic; Tonic inhibition; Thalamus
A new meaning for “Gin & Tonic”: tonic inhibition as the target for ethanol action in the brain
Keywords: مهار تونیک; GABAARs; Ethanol; Inhibition; Tonic inhibition; Neurosteroids
Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition
Keywords: مهار تونیک; Alpha6 subunit; Alpha4 subunit; Delta subunit; Alcohol; Cerebellum; Tonic inhibition
Exposure to novelty and forced swimming evoke stressor-dependent changes in extracellular GABA in the rat hippocampus
Keywords: مهار تونیک; in vivo microdialysis; GABA; stress; D-Phe-CRF12-41; tonic inhibition; temperatureANOVA, analysis of variance; CRF, corticotropin-releasing factor; HPA, hypothalamic-pituitary-adrenocortical; HPLC, high performance liquid chromatography; OPA, o-phthaldial
Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice
Keywords: مهار تونیک; Spinal dorsal horn; Nociceptive transmission; Nicotinic receptors; Tonic inhibition; Whole cell patch clamp; Substantia gelatinosa; Inhibitory postsynaptic currents;
The α5 GABAA receptor subunit confers resistance to isoflurane inhibition
Keywords: مهار تونیک; GABA; Isoflurane; Tonic inhibition; α5 subunit; Hippocampus;