TPH2 polymorphisms may modify clinical picture in treatment-resistant depression
Keywords: TPH2; Polymorphism; ECT; Treatment-resistant depression
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TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression
Keywords: HDRS, Hamilton's Depression Rating Scale; LSARS, the Lethality Suicide Attempt Rating Scale; MDD, major depressive disorder; RRR, Weisman and Worden's risk-rescue rating; TPH, tryptophan hydroxylaseHTR1A; HTR2A; Polymorphism; Serotonin; Suicide; TPH2
Estrogen decreases 5-HT1B autoreceptor mRNA in selective subregion of rat dorsal raphe nucleus: Inverse association between gene expression and anxiety behavior in the open field
Keywords: 5-HT; tryptophan hydroxylase; 5-HT1A; in situ hybridization; ovarian hormones; ovariectomy; cDM; caudal dorsomedial dorsal raphe nucleus; cVM; caudal ventromedial dorsal raphe nucleus; DRN; dorsal raphe nucleus; ISHH; in situ hybridization histochemistry;
Predominant expression of tryptophan hydroxylase 1 mRNA in the pituitary: A postmortem study in human brain
Keywords: TPH1; TPH2; mRNA; antibody; postmortem; pituitaryCON, controls; DA, drug abusers; DRN, dorsal raphe nuclei; HPA, hypothalamic–pituitary–adrenal; SU, suicide victims; SZ, schizophrenic; TPH, tryptophan hydroxylase; TPH1, tryptophan hydroxylase 1; TPH2, try
Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus
Keywords: anxiety; depression; maternal separation; serotonin; stress; tryptophan hydroxylase; AFR; animal facility rearing; ANOVA; analysis of variance; CLi; caudal linear nucleus of the raphe; DR; dorsal raphe nucleus; DRD; dorsal raphe nucleus, dorsal part; DRI;
Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: Convergent data from Tph2 knockout mice
Keywords: Tph1; Tph2; Serotonin; Development; Raphe nuclei; Pineal gland
Imaging phenotypes of major depressive disorder: genetic correlates
Keywords: endophenotype; 5-HT1A receptor; serotonin transporter; major depressive disorder; genome-wide association; epigenetics; AD; antidepressant medication; BA; Brodmann area; BD; bipolar disorder; BNST; basal nucleus of the stria terminalis; BOLD; blood oxygen
P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
Keywords: 5-HTTLPR; serotonin transporter gene-linked polymorphic region; BDNF; brain-derived neurotrophic factor; P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; TPH2; tryptophan hydroxylase 2; DM; diabetes mellitus; GC; good glycemic control group (H
No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover
Keywords: TPH2; Single nucleotide polymorphism; Bipolar disorder; Major depressive disorder; Suicide attempt
Utilization of a two-standard system in real-time PCR for quantification of gene expression in the brain
Keywords: 5-HT1A receptor; Tph2; mRNA level; RT-PCR; Real-time RT-PCR; Catalepsy
Genes regulating the serotonin metabolic pathway in the brain stem and their role in the etiopathogenesis of the sudden infant death syndrome
Keywords: 5-HTT; MAOA; TPH2; Molecular polymorphisms; SIDS; Neurotransmitter
Rhesus monkey tryptophan hydroxylase-2 coding region haplotypes affect mRNA stability
Keywords: TPH2; 5-HT; nonsynonymous polymorphisms; gene expression; nonhuman primate; AA; amino acid; ADHD; attention deficit hyperactivity disorder; ANOVA; analysis of variance; CDSN; corneodesmosin; CSTA; cystatin A; DRB; 5,6-dichlororibofuranosyl benzimidazole;
Expression of the transcription factor GATA3 in the postnatal mouse central nervous system
Keywords: 3V; third ventricle; 4V; fourth ventricle; APT; anterior pretectal nucleus; Aq; aqueduct; Cb; cerebellum; Cx; cerebral cortex; CNS; central nervous system; Co; cochlear nucleus; DT; dorsal tegmental nucleus; DLG; dorsal lateral geniculate nucleus; DpMe; d
Association study of tryptophan hydroxylase 2 gene polymorphisms in panic disorder
Keywords: Panic disorder; Tryptophan hydroxylase; TPH2; Genetic polymorphism
Nested Association Between Genetic Variation in Tryptophan Hydroxylase II, Bipolar Affective Disorder, and Suicide Attempts
Keywords: TPH2; attempt suicide; bipolar disorder; Genetics; Genetic Variation; polymorphism
A new gain-of-function allele in chimpanzee tryptophan hydroxylase 2 and the comparison of its enzyme activity with that in humans and rats
Keywords: TPH2; SNP; 5HTP; Chimpanzee; Serotonin
Characterization of a Functional Promoter Polymorphism of the Human Tryptophan Hydroxylase 2 Gene in Serotonergic Raphe Neurons
Keywords: Brain-2; haplotype; POU transcription factor; serotonin; SHP-77 cells; single nucleotide polymorphism; TPH2
Estrogen Selectively Increases Tryptophan Hydroxylase-2 mRNA Expression in Distinct Subregions of Rat Midbrain Raphe Nucleus: Association between Gene Expression and Anxiety Behavior in the Open Field
Keywords: Ovarian hormones; progesterone; serotonin; TPH2; dorsal raphe; median raphe