دانلود مقالات ISI درباره Tpp1 + ترجمه فارسی

نقش جدید تغذیه و چشم انداز غیر کدینگ در دیابت نوع 2: بررسی ادبیات

Emerging role of nutrition and the non-coding landscape in type 2 diabetes mellitus: A review of literature

Keywords: ABCC8; ATP Binding Cassette Subfamily C Member 8; CAPN10; calpain 10; Cdkal1; Cdk5 regulatory associated protein 1-like 1; DM; diabetes mellitus; GLIS3; GLIS Family Zinc Finger 3; HMGA1; high mobility group A1; HNF1A; hepatocyte nuclear factor 1A; HNF1Î

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

درمان های در حال ظهور برای اختلالات ذخیره سازی لیزوزومی نوروپاتی

Emerging therapies for neuropathic lysosomal storage disorders

Keywords: LSD; lysosomal storage disease; CNS; central nervous system; BBB; blood-brain barrier; ERT; enzyme replacement therapy; GAG; glycosaminoglycans; CSF; cerebrospinal fluid; FDA; food and drug administration; ICV; intracerebroventricular; HLA; human leukocyt

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2017 سفارش ترجمه

درمان جایگزینی آنزیم اینتراکتال، عملکرد حرکتی و بقا را در یک مدل موش پیش از مواجهه با لیپوفوس کینوز سئول نرون لخت

Intrathecal enzyme replacement therapy improves motor function and survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis

Keywords: ERT; enzyme replacement therapy; CLN1; ceroid lipofuscinosis, neuronal-1; CLN2; ceroid lipofuscinosis, neuronal-2; LSD; lysosomal storage disorder; MU-6S-Palm-βGlc; 4-methylumbelliferyl-6-thiopalmitoyl-β-d-glucoside; NCL; neuronal ceroid lipofuscinosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Characteristics of PPT1 and TPP1 enzymes in neuronal ceroid lipofuscinosis (NCL) 1 and 2 by dried blood spots (DBS) and leukocytes and their application to newborn screening

Keywords: TPP1; PPT1; NCL1; NCL2; pH optimum; Newborn screening;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Immunogenicity to cerliponase alfa intracerebroventricular enzyme replacement therapy for CLN2 disease: Results from a Phase 1/2 study

Keywords: Cerliponase alfa; Enzyme replacement therapy; CLN2; Neuronal ceroid lipofuscinosis; Anti-drug antibodies; Hypersensitivity; Immunogenicity; ADA; anti-drug antibody; ICV; intracerebroventricular.; ML; motor-language.; NAb; neutralizing anti-drug antibody.;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Expression profiling of genes encoding ABA route components in response to dehydration or various light conditions in poplar buds and leaves

Keywords: ABA; abscisic acid; ABI1 or 2; ABA-insensitive 1 or 2; ABI5; ABA-insensitive 5; ACO; 1-aminocyclopropane-1-carboxylate oxidase; ARR2; arabidopsis response regulator 2; AtI-2; arabidopsisInhibitor-2; CTR1; constitutive triple response 1; EIN2; ethylene ins

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Secretion and function of Cln5 during the early stages of Dictyostelium development

Keywords: Acb; acyl-coenzyme-binding protein; BFA; brefeldin A; bsr; blasticidin resistance; cAMP; cyclic adenosine monophosphate; CTS; cathepsin; CLN; ceroid lipofuscinosis neuronal; CM; conditioned media; CMF; conditioned media factor; CV; contractile vacuole; CQ

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Correlation between telomerase and mTOR pathway in cancer stem cells

Keywords: CSCs; cancer stem cells; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AKT; serine/threonine kinase 1; hTERT; human telomerase reverse transcriptase; TERC; telomerase RNA component; GBM; glioblastoma multiforme; TRF1; telomeric rep

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype

Keywords: TPP1; protein encoded by adrenocortical dysplasia gene; Acd; adrenocortical dysplasia gene; acd; adrenocortical dysplasia mutation; p53; transformation related protein 53; DNA; Deoxyribonucleic acid; DC; Dyskeratosis congenita; HHS; Hoyeraal-Hreidarsson s

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of metal ions and cosolutes on G-quadruplex topology

Keywords: PCR; polymerase chain reaction; dX; 2′-deoxyxanthosine; oxodG; 8-oxo-2′-deoxyguanine; CPG; controlled pore glass; ODN; oligodeoxyribonucleotide; NPE; 2-(4-nitrophenyl)ethyl; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; PAGE; polyacrylamide gel electrophor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Regulated expression of the lncRNA TERRA and its impact on telomere biology

Keywords: TERRA; telomere repeat-containing RNA; TRF1/2; telomeric repeat-binding factors 1 and 2; POT1; protection of telomeres 1; TIN2; TRF1-interacting nuclear factor 2; TPP1; adrenocortical dysplasia protein homologue (also called ACD, PTOP, PIP1 & TINT1); RAP1

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity

Keywords: ZSCAN4; TRF1; Cancer; Telomeres; Telomerase; ALT pathway; ALT; alternative lengthening of telomeres; BIFC; bimolecular fluorescence complementation; Co-IP; co-immunoprecipitation; ESC; embryonic stem cells; GST; glutathione S-transferase; PinX1; PIN2/TERF

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Multifocal retinopathy in Dachshunds with CLN2 neuronal ceroid lipofuscinosis

Keywords: Dog; Canine; Neuronal ceroid lipofuscinosis; Bullous retinopathy; Retinal detachment; TPP1; CLN2; BEST1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleChronic replicative stress induced by CCl4 in TRF1 knockout mice recapitulates the origin of large liver cell changes

Keywords: TRF1 and TRF2; Telomeric repeat binding factors 1 and 2; TIN2; tTRF1-interacting protein 2; POT1; Protection of telomeres 1; TPP1; POT1-TIN2 organizing protein; RAP1; Repressor activator protein 1; LLCC; Large liver cell changes; SLCC; Small liver cell ch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs

Keywords: Telomere; POT1; TPP1; DNA-binding; OB-fold;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Suppression of telomere-binding protein TPP1 resulted in telomere dysfunction and enhanced radiation sensitivity in telomerase-negative osteosarcoma cell line

Keywords: TPP1; Telomere; Osteosarcoma; Radiosensitivity; ALT;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Multiple facets of TPP1 in telomere maintenance

Keywords: Telomere; TPP1; Shelterin; Telomerase; DNA damage; Chromosome stability;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleTelomere length, TERT and shelterin complex proteins in hepatocellular carcinomas expressing “stemness”-related markers

Keywords: HCC; hepatocellular carcinoma; K19; keratin 19; EpCAM; epithelial cell adhesion molecule; TGF-β; transforming growth factor-β; TRF; telomeric repeat-binding factor; TIN2; TRF1-interacting protein 2; POT1; protection of telomeres 1; TPP1; POT1-TIN2 organ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Neuronal ceroid lipofuscinosis type CLN2: A new rationale for the construction of phenotypic subgroups based on a survey of 25 cases in South America

Keywords: CB; curvilinear body; DBS; dried blood spot; FP; fingerprint profile; GROD; granular osmiophilic deposit; J-NCL; juvenile NCL; LD; lysosomal disorder; LI-NCL; late-infantile NCL; NCLs; neuronal ceroid lipofuscinoses; PDB; protein data bank; PolyPhen-2; po

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه