Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DR5 up-regulation: Involvement of Ca2+ influx
Keywords: قطار; Capsaicin; TRAIL; DR5; Sp1; Ca2+;
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Ad-KDRscFv:sTRAIL displays a synergistic antitumor effect without obvious cytotoxicity to normal tissues
Keywords: قطار; KDRscFv; TRAIL; Gene fusion; Replication-defective; Recombinant adenovirus;
Enriching the human apoptosis pathway by predicting the structures of protein-protein complexes
Keywords: قطار; AIF; apoptosis-inducing factor, mitochondrion-associated, 1; Apaf-1; apoptotic peptidase activating factor 1; Bax; BCL2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-XL; Bcl-extra large; Bid; BH3 interacting domain death agonist; CASP3; caspase-3; C
Sarcomas as a mise en abyme of mesenchymal stem cells: Exploiting interrelationships for cell mediated anticancer therapy
Keywords: قطار; Sarcoma; Mesenchymal stem cell; Cell therapy; Radiation; TRAIL
IFN-γ combined with targeting of XIAP leads to increased apoptosis-sensitisation of TRAIL resistant pancreatic carcinoma cells
Keywords: قطار; Apoptosis; TRAIL; XIAP; Pancreatic cancer; Interferon; Caspase-8
Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells
Keywords: قطار; HCC; hepatocellular carcinoma; IAP; inhibitor of apoptosis; SMAC; second mitochondrial activator of caspases; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; PARP; polypolymerase; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine
Impairment of hepatic NK cell development in IFN-γ deficient mice
Keywords: قطار; HSC; haematopoietic stem cell; NK cell; nature killer cell; NKP; nature killer cell precursor; LN; lymph node; TRAIL; tumour necrosis factor-related apoptosis-inducing ligand; PBS; phosphate-buffered saline; MNCs; mononuclear cells; RBC; red blood cells
IFN-γ-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand
Keywords: قطار; Mesenchymal stem cells; IFN-γ; TRAIL; Tumor cells; Apoptosis;
Hypersensitivity of A8344G MERRF mutated cybrid cells to staurosporine-induced cell death is mediated by calcium-dependent activation of calpains
Keywords: قطار; CPEO; Chronic Progressive External Ophthalmoplegia; KSS; Kearns-Sayre Syndrome; LHON; Leber's Hereditary Optic Neuropathy; MELAS; Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-like episodes; MERRF; Myoclonic Epilepsy with Ragged Red Fibers;
Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis
Keywords: قطار; Human T cells; Trauma; TRAIL; Apoptosis; CD47
Doxorubicin-loaded human serum albumin nanoparticles surface-modified with TNF-related apoptosis-inducing ligand and transferrin for targeting multiple tumor types
Keywords: قطار; TRAIL; Albumin nanoparticles; Apoptosis; Doxorubicin; Tumor targeting;
TRAIL-activated EGFR by Cbl-b-regulated EGFR redistribution in lipid rafts antagonises TRAIL-induced apoptosis in gastric cancer cells
Keywords: قطار; TRAIL; EGFR; Lipid rafts; Cbl-b;
Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest
Keywords: قطار; Colon cancer; TNF; TRAIL; HDAC inhibitors; Aurora kinase inhibitors
The role of dendritic cells in asthma
Keywords: قطار; Dendritic cells; asthma; allergen; TH2 inflammation; BALF; Bronchoalveolar lavage fluid; BDCA; Blood dendritic cell antigen; cDC; Conventional dendritic cell; DC; Dendritic cell; HDM; House dust mite; IDO; Indoleamine 2,3-dioxygenase; ILT7; Immunoglobulin
The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells
Keywords: قطار; TRAIL; tumor necrosis factor-related apoptosis inducing ligand; DR; death receptor; HNSCC; head and neck squamous cell carcinoma; MOMP; mitochondrial outer membrane permeabilization; mAb; monoclonal antibody; CI; combination index.; TRAIL receptors; Prote
Histone modifications as a pathogenic mechanism of colorectal tumorigenesis
Keywords: قطار; AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem
The molecular mechanism of apoptosis upon caspase-8 activation: Quantitative experimental validation of a mathematical model
Keywords: قطار; ARK5; AMPK-related protein kinase 5; Bid; BH3-interacting domain death agonist; CARP; caspases-8- and -10-associated RING protein; CASP; caspase; CHX; cycloheximide; DED; death effector domain; DISC; death-inducing signaling complex; EGFP; enhanced green
Targeting p53 as a therapeutic strategy in sensitizing TRAIL-induced apoptosis in cancer cells
Keywords: قطار; TRAIL; p53; Apoptosis; Sensitization; Cancer;
First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: A Phase I/II open-label and double-blind study
Keywords: قطار; Conatumumab; Doxorubicin; Soft tissue sarcomas; Death receptor 5; TRAIL
DNA methylation-based biomarkers in serum of patients with breast cancer
Keywords: قطار; 5-Aza-CdR; 5-aza-2â²-deoxycytidine; 5-Aza-CR; 5-azacytidine; 5mC; 5-methylcytidine; AIMS; amplification of inter-methylated sites; APC; adenomatous polyposis coli; BiMP; bisulfite methylation profiling; BRCA1; breast cancer gene 1; BsPP; bisulfite padloc
p53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: A mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis
Keywords: قطار; TRAIL; Glioma; p53; DR5; Proteasome inhibitor; Velcade; Bortezomib
Effects of modified Haizao Yuhu Decoction in experimental autoimmune thyroiditis rats
Keywords: قطار; HYD; Haizao Yuhu Decoction; MHYD; modified Haizao Yuhu Decoction; DL-S; MHYD lacking Sargassum fusiforme; DL-G; MHYD lacking Radix Glycyrrhiza; EAT; experimental autoimmune thyroiditis; HT; hashimoto's thyroiditis; TRAIL; TNF-related apoptosis-inducing li
Association of serum TRAIL levels with atherosclerosis in patients with type 2 diabetes mellitus
Keywords: قطار; TRAIL; Atherosclerosis; Ultrasonography; Vascular calcification; Diabetes;
Augmenter of liver regeneration (ALR) protects human hepatocytes against apoptosis
Keywords: قطار; rhALR; recombinant human augmenter of liver regeneration; EGF; epidermal growth factor; ERK-1/2; extracellular signal-regulated kinase 1/2; FCS; fetal calf serum; HGF; hepatocyte growth factor; LPS; lipopolysaccharide; MAP kinase; mitogen-activated prot
Preclinical toxicity of DATR, a recombinant soluble human TRAIL mutant, in rats and cynomolgus monkeys
Keywords: قطار; DATR; TRAIL; Toxicity; Chemotherapeutic;
Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells
Keywords: قطار; TRAIL; Anoikis; PI3K/Akt pathway; Colon cancer
Synergy between TLR3 and IL-18 promotes IFN-γ dependent TRAIL expression in human liver NK cells
Keywords: قطار; TLR3; IFN-γ; TRAIL; Liver NK cells; IL-18
Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression
Keywords: قطار; eEF-2 kinase; TRAIL; Bcl-xl; Apoptosis; Glioblastoma;
Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma
Keywords: قطار; Cancer of the pancreas; PDAC; Apoptosis; Death receptor; TNF; TRAIL; CD95L; Signal transduction
5-azacytidine, a chemotherapeutic drug, induces TRAIL-mediated apoptosis in mouse thymocytes in vivo
Keywords: قطار; 5-azacytidine (5AzC); Apoptosis; Thymocyte; Mice; TRAIL
Orientation in corpse-carrying ants: memory or chemical cues?
Keywords: قطار; ant; memory; Myrmica rubra; necrophoresis; trail
Differential immunotoxicity of histone deacetylase inhibitors on malignant and naïve hepatocytes
Keywords: قطار; TNF; TRAIL; CD95L; cFLIP; XIAP; Hepatocellular carcinoma; Adverse side effect; Primary hepatocytesActD, actinomycin D; CBHA, m-carboxycinnamic acid bis-hydroxamide; HDAC, histone deacetylase; HDI, histone deacetylase inhibitor; M344, N-hydroxy-7-(-4-dimet
PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity
Keywords: قطار; TRAIL; PEGylation; PLGA microspheres; Stability; Sustain release; Antitumor
Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression
Keywords: قطار; TRAIL; Apoptosis; ROS; CML
TRADD is critical for resistance to TRAIL-induced cell death through NF-κB activation
Keywords: قطار; TRADD; NF-κB; TRAIL; Cell death;
Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry
Keywords: قطار; Bcl-xL; B-cell leukemia-xL; CDDP; cis-diammine-dichloro-platinum; DETANONOate; (Z)-1-[2-(2-aminoethyl)-N-(2-ammonio-ethyl) amino] diazen-1-ium-1, 2-diolate; DHMEQ; dehydroxymethylepoxyquinomicin; DR; death receptor; ERK; extracellular signal-regulated kin
The controversial links among calorie restriction, SIRT1, and resveratrol
Keywords: قطار; Ac; acetate; AMPK; AMP-activated kinase; CAECs; coronary arterial endothelial cells; CR; calorie restriction; CSE; cigarette smoke extract; eNOS; endothelial nitric oxide synthase; EX-527; 6-chloro-2,3,4,9-tetrahydro-1-H-carbazole-1-carboxamide; Fâ; flu
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults
Keywords: قطار; Cardiovascular disease; TRAIL; Mortality; Epidemiology; Aging;
TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice
Keywords: قطار; Apolipoprotein E-deficient mice; Atherosclerosis; TRAIL; Apoptosis;
Tumor Necrosis FactorâRelated ApoptosisâInducing Ligand (TRAIL) and Its Death Receptor (DR5) in Peyronie's Disease. A Biomolecular Study of Apoptosis Activation
Keywords: قطار; Peyronie's Disease; Peyronie's Plaque Healing; Apoptosis; TRAIL; DR5;
Causative agents of osteomyelitis induce death domain-containing TNF-related apoptosis-inducing ligand receptor expression on osteoblasts
Keywords: قطار; Osteoblasts; Osteomyelitis; Apoptosis; TRAIL; Staphylococcus aureus;
Death Receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells
Keywords: قطار; Pemetrexed; DR5; c-FLIP; Apoptosis; CHOP; TRAIL;
Interleukin-2 rescues helpless effector CD8+ T cells by diminishing the susceptibility to TRAIL mediated death
Keywords: قطار; T cells; Cytotoxic; Cytokines; CD8; TRAIL;
RESEARCH ARTICLESignal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
Keywords: قطار; HCC; hepatocellular carcinoma; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; STAT3; signal transducers and activators of transcription 3; NF-κB; nuclear factor-kappa B; PARP; polypolymerase; DMEM; Dulbecco's modified Eagle's medium;
Novel transcript variants of TRAIL show different activities in activation of NF-κB and apoptosis
Keywords: قطار; TRAIL; Transcript variant; Isoform; NF-κB; Apoptosis
Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization
Keywords: قطار; BIR; baculoviral IAP repeat; CCD; charge coupled device; CHX; Cycloheximide; C-XIAP-C; Cerulean-XIAP-Cerulean; STS; Staurosporine; TRAIL; tumor necrosis factor-related apoptosis inducing ligand; Apoptosis; x-Linked inhibitor of apoptosis protein (XIAP); S
Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation
Keywords: قطار; Piceatannol; TRAIL; Death receptor; Sp1; ERK;
Polyphenol acertannin prevents TRAIL-induced apoptosis in human keratinocytes by suppressing apoptosis-related protein activation
Keywords: قطار; TRAIL; Acertannin; Human keratinocytes; Apoptosis-related proteins; Cell protection;
Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways
Keywords: قطار; TNF; TNF-receptosomes; CD95; TRAIL; Caspase; Sphingomyelinase; Ceramide; Cathepsin D; Apoptosis
iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes
Keywords: قطار; iNOS; inducible nitric oxide synthase; NO; nitric oxide; GCDC; glycochenodeoxycholate; SNAP; S-nitroso-N-acetyl-penicillamine; SNP; sodium nitroprusside; PI3K; Phosphoinositide 3-kinase; NF-κB; nuclear factor kappaB; p38MAPK; P38 mitogen-activated protei