Keywords: Warfarin; Anticoagulation; Thromboembolism; CYP2C9; VKORC1; Surgery;
مقالات ISI (ترجمه نشده)
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Keywords: Medicinal plants; North Eastern region; Morocco; Toxic plants; Alkaloids; AT; acute toxicity; ATR; atractyloside; C; cultivated; CA; cutaneous application; CATR; carboxyatractyloside; CBCH; cannabichromene; CBD; cannabidiol; CBN; cannabinol; CT; chronic t
Keywords: Body mass index; CYP2C9; CYP4F2; Gene-environment interaction; Major bleeding; VKORC1; Warfarin;
Keywords: Atrial fibrillation; CYP2C9; VKORC1; warfarin; polymorphism; stroke;
Keywords: AD; Alzheimer's disease; CST; cerebroside sulfotransferase; DE; dabigatran etexilate; VKORC1; vitamin K oxidoreductase subunit 1; GGC; gamma-glutamyl carboxylase; VKDPs; vitamin K dependent proteins; Astrocyte; Dabigatran; Microglia; Sulfatides; Vitamin K
Keywords: Stroke; Warfarin; CYP2C9; VKORC1; Polymorphisms;
Keywords: Warfarin; Pharmacogenetics; CYP2C9; VKORC1; Meta analysis;
Keywords: CYP2C9; cytochrome P-450 variant 2C9; VKORC1; vitamin K epoxide reductase complex-1; SNP; single-nucleotide polymorphism; PCR; polymerase chain reaction; Warfarin; Microarray; SNP; Lateral flow cell; Saliva;
Brodifacoum as a first choice rodenticide for controlling bromadiolone-resistant Mus musculus
Keywords: House mouse; Resistance; Storages; VKORC1; Brodifacoum;
Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses
Keywords: ACE; angiotensin converting enzyme; ARB; angiotensin II receptor blocker; BMI; body mass index; CYP; cytochrome P 450; EPHX1; epoxide hydrolase 1; GGCX; γ-glutamyl carboxylase; INR; international normalized ratio; KH2; vitamin K hydroxyquinone; KO; vitam
Weight and the vitamin K expoxide reductase 1 genotype primarily contribute to the warfarin dosing in pediatric patients with Kawasaki disease
Keywords: KD; Kawasaki disease; CAA; coronary artery aneurysm; GCAA; giant coronary artery aneurysm; INR; international normalized ratio; SNP; single nucleotide polymorphism; VKORC1; vitamin K expoxide reductase; CYP2C9; cytochrome P4502C9; BSA; body surface area;
Bleeding predictors in patients following venous thromboembolism treated with vitamin K antagonists: Association with increased number of single nucleotide polymorphisms
Keywords: Venous thromboembolism; Vitamin K antagonists; Acenocoumarol; Warfarin; Genetic polymorphisms; AF; atrial fibrillation; APOE; apolipoprotein E; AUC; area under the curve; CI; confidence interval; CRNM bleeding; clinically relevant non-major bleeding; CYP2
A simple, sensitive, and high-throughput LC-APCI-MS/MS method for simultaneous determination of vitamin K1, vitamin K1 2,3-epoxide in human plasma and its application to a clinical pharmacodynamic study of warfarin
Keywords: VK1; vitamin K1; VK1O; vitamin K1 2,3-epoxide; VKOR; vitamin K epoxide reductase; VKORC1; vitamin K epoxide reductase complex subunit 1; IS; internal standard; S/N; signal-to-noise ratio; GGCX; gamma-glutamyl carboxylase; Glu; glutamic acid; Gla; gamma ca
CYP2C9 and VKORC1 in therapeutic dosing and safety of acenocoumarol treatment: implication for clinical practice in Hungary
Keywords: AC; acenocoumarol; VKA; vitamin K antagonist; NOACs; novel oral anticoagulants; OEP; Hungarian acronym, National Health Insurance Fund of Hungary; INR; International Normalized Ratio; CYP2C9; Cytochrome P450 2C9; VKORC1; Vitamin K Epoxide Reductase Comple
Speculations on vitamin K, VKORC1 genotype and autism
Keywords: Autism; VKORC1; Vitamin K; Autism etiology; Somali;
A model analysis for dose-response relationship of warfarin in Japanese children: An introduction of the SIZE parameter
Keywords: Warfarin; Growth and development; Japanese pediatric patients; VKORC1; Bosentan;
Evaluation of 16 genotype-guided Warfarin Dosing Algorithms in 310 Korean Patients Receiving Warfarin Treatment: Poor Prediction Performance in VKORC1 1173C Carriers
Keywords: CYP2C9; genotype-guided algorithm; VKORC1; warfarin;
Impact of CYP2C9, VKORC1 and CYP4F2 genetic polymorphisms on maintenance warfarin dosage in Han-Chinese patients: A systematic review and meta-analysis
Keywords: INR; International Normalized Ratio; CYP2C9; Cytochrome P450 Complex Subunit 2C9; CYP4F2; Cytochrome P450 Complex Subunit 4F2; VKORC1; Vitamin K Epoxide Reductase Complex Subunit 1; SNPs; Single Nucleotide Polymorphisms; MDWD; Mean Daily Warfarin Dose; CI
Comparison of rivaroxaban mono-therapy and standard-therapy adjusted by CYP2C9 and VKORC1 genotypes in symptomatic pulmonary embolism
Keywords: Pulmonary embolism; Rivaroxaban; CYP2C9; VKORC1; Deep venous thrombosis;
Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy
Keywords: Warfarin; Vitamin K1; Menaquinone-4; CYP4F2; VKORC1; CYP2C9;
Genotype frequencies of VKORC1 and CYP2C9 in Native and Mestizo populations from Mexico, potential impact for coumarin dosing
Keywords: CYP2C9, cytochrome P-450, family 2, subfamily C9; VKORC1, vitamin K oxidoreductase complex 1Mexican populations; CYP2C9; VKORC1
The influence of VKORC1 gene polymorphism on warfarin maintenance dosage in pediatric patients: A systematic review and meta-analysis
Keywords: Warfarin; Pediatric patients; VKORC1; Gene polymorphisms; Systematic review; Meta-analysis; CI; confidence interval; SD; standard DEVIATION; SNPs; Single nucleotide polymorphisms; CYP2C9; cytochrome P450 complex subunit 2C9; VKORC1; vitamin K epoxide redu
Extrapolation of acenocoumarol pharmacogenetic algorithms
Keywords: Pharmacogenetics; VKORC1; Dosing algorithms; Extrapolation; Acenocoumarol;
Comparative inhibitory effect of prenylated coumarins, ferulenol and ferprenin, contained in the 'poisonous chemotype' of Ferula communis on mammal liver microsomal VKORC1 activity
Keywords: VKOR; vitamin K epoxide reductase; VKORC1; vitamin K epoxide reductase complex subunit 1; Vitamin KÂ >Â O; vitamin K epoxide; Ferula communis L. (Apiaceae); Ferulenol; Ferprenin; VKORC1; Inhibition constant; Interspecies variability;
Prevalence of genetic polymorphisms of CYP2C9 and VKORC1 — Implications for warfarin management and outcome in Croatian patients with acute stroke
Keywords: Stroke; Warfarin; Genetic polymorphism; CYP2C9; VKORC1
VKORC1 and CYP2C9 genotype distribution in Asian countries
Keywords: VKORC1; CYP2C9; Asia; Warfarin;
Resequencing of VKORC1, CYP2C9 and CYP4F2 genes in Italian patients requiring extreme low and high warfarin doses
Keywords: Warfarin; Pharmacogenetics; Polymorphism; VKORC1; CYP2C9; CYP4F2;
Allele frequency distribution of CYP2C9*2 and CYP2C9*3 polymorphisms in six Mexican populations
Keywords: CEPH-HGDP; Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Project; CYP; cytochrome P-450; CYP2C9; cytochrome P-450 CYP2C9 gene; CYP2C9*1; allele 1 of the CYP2C9 gene; CYP2C9*2; allele 2 of the CYP2C9 gene; CYP2C9*3; allele 3 of the CYP2C9 g
Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay
Keywords: DTT; dithiothreitol; VKOR; vitamin K 2,3-epoxide reductase; VKORC1; vitamin K 2,3-epoxide reductase complex subunit 1; DTT-driven enzyme assay; Inhibition; VKOR; VKORC1; Vitamin K; Warfarin;
Sex differences in the effective warfarin dosage in Han and aboriginal Taiwanese patients with the VKORC1-1639AA genotype
Keywords: Aborigines; CYP2C9; Genetic polymorphism; VKORC1; Warfarin
Influence of CYP2C9 and VKORC1 gene polymorphisms on warfarin dosage, over anticoagulation and other adverse outcomes in Indian population
Keywords: CYP2C9; VKORC1; Warfarin; India
The impact of the CYP2C9 and VKORC1 polymorphisms on acenocoumarol dose requirements in a Romanian population
Keywords: Acenocoumarol; Romanian population; Genetic variability; CYP2C9; VKORC1
New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) - The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations
Keywords: VKORC1; Mutation; Vitamin K; Hydroxyvitamin K; Catalytic mechanism; AVK; antivitamin K anticoagulant; VKORC1; vitamin K epoxide reductase; vit K; vitamin K; vit K>O; vitamin K2,3-epoxide; OH-vit K; hydroxyvitamin K; vit KH2; vitamin K hydroquinone; VKDP;
Variability in CYP2C9 allele frequency: A pilot study of its predicted impact on warfarin response among healthy South and North Indians
Keywords: warfarin; acenocoumarol; India; thrombosis; drug response; adverse effects; CYP2C9; VKORC1
Effect of CYP2C9 and VKORC1 genetic variations on warfarin dose requirements in Indian patients
Keywords: CYP2C9; genetic variations; Indians; VKORC1; warfarin
A novel VKORC1 promoter mutation found causing warfarin resistance, along with –1639G>A promoter mutation—A pilot study on the genetic variation in patients on warfarin therapy in South India
Keywords: ARMS PCR; CYP2C9; genotype; VKORC1; warfarin
Evaluation of the warfarin-resistance polymorphism, VKORC1 Asp36Tyr, and its effect on dosage algorithms in a genetically heterogeneous anticoagulant clinic
Keywords: VKORC1; CYP2C9; Warfarin; Genetic determinants; Association studies; Dosage algorithm
Comparative performance of warfarin pharmacogenetic algorithms in Chinese patients
Keywords: Warfarin; pharmacogenetics; low intensity anticoagulation; CYP2C9; VKORC1; CYP4F2
Influence of CYP4F2 genotype on warfarin dose requirement-a systematic review and meta-analysis
Keywords: INR; International Normalized Ratio; CYP2C9; CytochromeP450 Complex Subunit2C9; VKORC1; Vitamin K Epoxide Reductase Complex Subunit 1; CYP4F2; CytochromeP450 Complex Subunit 14Â F2; CI; Confidence Interval; HLM; Human Liver Microsomes; MDWD; Mean Daily Wa
Cardiovascular pharmacogenetics
Keywords: ABCB1; Human ABC transporter molecule; ACE; Angiotensin-converting enzyme; ADRB; Beta-adrenergic receptor gene; AF; Atrial fibrillation; ApoE; Apolipoprotein E; AR; Adrenergic receptor; CHD; Coronary heart disease; CYP; Cytochrome P450 enzyme; DCM; Dilate
Failure of Pharmacogenetic-based Dosing Algorithms to Identify Older Patients Requiring Low Daily Doses of Warfarin
Keywords: Warfarin; genotyping; pharmacogenomics; elderly; CYP2C9; VKORC1; renal disease;
Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes
Keywords: Warfarin; Phenprocoumon; Acenocoumarol; CYP2C9; VKORC1; Point of care genotyping;
Development and Comparison of a Warfarin-Dosing Algorithm for Korean Patients With Atrial Fibrillation
Keywords: atrial fibrillation; CYP2C9; Korean; VKORC1; warfarin
New adjuvants to enhance anticoagulant activity of Warfarin
Keywords: Warfarin; Anti-coagulation; VKORC1; Agonist; Antagonist
VKORC1 V66M mutation in African Brazilian patients resistant to oral anticoagulant therapy
Keywords: CYP2C9, cytochrome P-450 2C9; VKORC1, vitamin K epoxide reductase complex subunit 1; INR, international normalized ratio; ml, milliliters; SDS, sodium dodecil sulfate; SNPs, single nucleotide polymorphismsWarfarin; VKORC1; CYP2C9; Genetic variability; Pha
A regression model to predict warfarin dose from clinical variables and polymorphisms in CYP2C9, CYP4F2, and VKORC1: Derivation in a sample with predominantly a history of venous thromboembolism
Keywords: Regression model; Pharmacogenomics; CYP2C9; VKORC1; CYP4F2
Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke
Keywords: Stroke; Coagulation factors; Genotype polymorphism; NQO1; GGCX; VKORC1;
CYP2C9 and VKORC1 genotypes in Puerto Ricans: A case for admixture-matching in clinical pharmacogenetic studies
Keywords: Admixture-matching; Puerto Ricans; Pharmacogenetics; VKORC1; CYP2C9 genotypes;
Investigation of allele and genotype frequencies of CYP2C9, CYP2C19 and VKORC1 in Iran
Keywords: CYP2C9; CYP2C19; VKORC1; Iranian; genotype
Pharmacogénétique et antivitamine K aujourd’hui : un débat ouvert
Keywords: Antivitamines K; VKORC1; CYP2C9; PharmacogénétiqueVitamin K antagonists; VKORC1; CYP2C9; Pharmacogenetics