Keywords: Abnormal Involuntary Movement Scale; Antipsychotic; Deutetrabenazine; Dopamine; Tardive dyskinesia; Valbenazine; VMAT2;
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Keywords: AC927; 1-(2-phenylethyl)piperidine; AMPH; amphetamine; ATS; amphetamine-type stimulants; AZ66; 3-(4-(4-cyclohexylpiperazin-1-yl)pentyl)-6-flourobenzo(Abadias et al., 2013)thiazol-2(3H)-one; BD1008; N-(Brammer et al., 2006)-N-methyl-1-pyrrolidineethanamine
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: Dopamine; Ecstasy; Methamphetamine; METH; 3,4-Methylenedioxymethamphetamine; MDMA; Mouse; Neurodegeneration; Neuroinflammation neurotoxicity; Non-human primate; Rat; AC; adenylyl cyclase; AcbSh; nucleus accumbens shell; AcbC; nucleus accumbens core; cAMP;
Keywords: Abnormal Involuntary Movement Scale; Antipsychotic; Deutetrabenazine; Dopamine; Tardive dyskinesia; Valbenazine; VMAT2;
Keywords: 6-OHDA; 6-hydroxydopamine; α-syn; α-synuclein; ACC; Anterior Cingulate Cortex; ADMA; asymmetric dimethylarginine; Alda-1; N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide; Aldh1/Aldh2; aldehyde dehydrogenases 1/2; ALDH2; mitochondrial aldehyde dehyd
Keywords: Lobelane; Piperazine analogs; VMAT2; Phenethyl bromides; Dopamine uptake
Keywords: 5-HT, 5-hydroxytryptamine serotonin; DA, dopamine; NE, norepinephrine; SERT, serotonin transporter; TPH2, tryptophan hydroxylase 2; VMAT2, vesicular monoamine transporter 2Serotonin; VMAT2; Synaptic vesicle; Dorsal raphe; Parkinson's disease; 5-HT1A; 5-HT
Keywords: 5-HIAA; 5-hydroxyindolacetic acid; 5-HT; 5-hydroxytryptamine; 5-HTP; 5- hydroxytryptophan; AADC; aromatic L-amino acid decarboxylase; ADR; acute dystonic reaction; BH4; tetrahydrobiopterin; CSF; cerebrospinal fluid; DRD; dopa-responsive dystonia; dRN; dor
Keywords: Dopamine; Exercise; Parkinson disease; Physical activity; PET; Sedentariness; CHAMPS; Community Health Activities Model Program for Seniors questionnaire; DTBZ; dihydrotetrabenazine; LED; levodopa equivalent dose; PD; Parkinson disease; PET; positron emis
Keywords: ADME; absorption/distribution/metabolism/excretion; BBB; blood-brain barrier; CD3OD; tetradeuteromethanol; CDCl3; deuterochloroform; CH2Cl2; dichloromethane; C log D; distribution coefficient; C log P; calculated partition coefficient; CNS; central
Keywords: Vesicle; SLC18A2; VMAT2; Transport;
Keywords: VMAT2; Norepinephrine; Parkinson's disease; Locus ceruleusDA, dopamine; DHPG, 3,4-dihydroxyphenylglycol; DOPAC, 3,4-dihydroxyphenylacetic acid; DOPAL, 3,4-dihydroxyphenylacetaldehyde; DOPEGAL, 3-4-dihydroxyphenylglycolaldehyde; LC, locus ceruleus; MAO, mo
Keywords: AChE histochemistry; Immunofluorescent labeling; Heart; Intrinsic cardiac neural plexus; Cardiac ganglia; Parasympathetic nerves; Sympathetic nerves; AChE; acetylcholinesterase; Ao; aorta; CGRP; calcitonin gene related peptide; ChAT; choline acetyltransfe
Keywords: GLU; Glucagon; INS; Insulin; IR; Immunoreactivity; PET; Positron emission tomography; PP; Pancreatic polypeptide; SOM; Somatostatin; T1DM; Type 1 diabetes model; VMAT2; Vesicular monoamine transporter;
Keywords: Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Keywords: 5-HIAA; 5 hydroxyindoleacetic acid; 5-HT; serotonin; 5-HTT; 5-HT transporter; ACTH; adrenocorticotropic hormone; AIAQ; anger irritability and assault questionnaire; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BCG; bacille Calmette-Gueri
Keywords: LSD; lysergic acid diethylamide; METH; (+)methamphetamine; MDMA; 3,4-methylenedioxymethylamphetamine; MDPV; 3,4-methylenedioxypyrovalerone; mephedrone; 4-methyl-N-methylcathinone; methylone; 3,4-methylenedioxy-N-methylcathinone; 4-FMC; 4-fluoromethcathino
Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice
Keywords: Juvenile mouse behaviour; Foetal alcohol exposure; Vitamin D deficiency; 25(OH)D; 25-hydroxyvitamin D (calcidiol); Aadc; aromatic L-amino acid decarboxylase; ADHD; attention deficit hyperactivity disorder; ASD; Autism spectrum disorder; COMT; comethyl tra
Aroclor 1254 and BDE-47 inhibit dopaminergic function manifesting as changes in locomotion behaviors in zebrafish embryos
Keywords: Catecholamine; Motor movement; Non-coplanar PCB; PBDE; Zebrafish; DOPAC; 3,4-dihydroxyphenylacetic acid; TH; tyrosine hydroxylase; VMAT2; vesicular monoamine transporter 2;
Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease
Keywords: α-Syn; alpha-Synuclein; h-α-Syn; transgenic human alpha-Synuclein; D1 receptor; dopamine receptor type 1; D2 receptor; dopamine receptor type 2; DA; dopamine; DAT; dopamine transporter; VMAT2; vesicular monoamine transporter 2; DOPAC; 3,4-dihydroxypheny
Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [3H]dopamine uptake at the vesicular monoamine transporter-2
Keywords: Lobelane; Fluoroethoxy piperidine and piperazine analogs; VMAT2; Dopamine uptake; hERG;
Association analysis of polymorphisms in VMAT2 and TMEM106B genes for Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy
Keywords: Parkinson's disease; Amyotrophic lateral sclerosis; Multiple system atrophy; VMAT2; TMEM106B; Polymorphisms;
Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells
Keywords: BCM; beta cell mass; DTBZ; dihydrotetrabenazine; DTPA; diethylenetriamine-pentaacetic acid; GFP; green fluorescent protein; GLP-1; glucagon-like peptide-1; MIP; mouse insulin I gene promotor; NOD; 1-(1,3-carboxypropyl)-1,4,7-triazacyclononane-4,7-diacetic
Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain
Keywords: VMAT2; Antibody; Monoamine; Immunochemistry; Vesicle; Brain; Localization; Vesicular monoamine transporter 2;
Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice
Keywords: 3α-diol; 5α-androstane-3α, 17β-diol; 3β-diol; 5α-androstane-3β, 17β-diol; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DHEA; dehydroepiandrosterone; DHP; 5α-dihydroprogesterone; DHT; dihydrotestost
Toxicity of the amphetamine metabolites 4-hydroxyamphetamine and 4-hydroxynorephedrine in human dopaminergic differentiated SH-SY5Y cells
Keywords: 4-OHAMPH; 4-hydroxyamphetamine; 4-OHNE; 4-hydroxynorephedrine; 5-HTT; serotonin transporter; β-NADH; β-nicotinamide adenine dinucleotide reduced form; ADHD; attention deficit hyperactivity disorder; AMPH; amphetamine; CHX; cycloheximide; DA; dopamine; D
Photoactivation of ERK/CREB/VMAT2 pathway attenuates MPP+-induced neuronal injury in a cellular model of Parkinson's disease
Keywords: PD; Parkinson's disease; SNpc; substantia nigra pars compacta; DA; dopamine; MPTP; 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; VMAT2; vesicular monoamine transporter 2; LPLI; low-power laser irradiation; Aβ; amyloi
Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry
Keywords: AADC; aromatic L amino acid decarboxylase; COMT; catechol-O-methyl-transferase; CSF; cerebrospinal fluid; 6-OHDA; 6-hydroxydopamine; DBH; dopamine β-hydroxylase; DOPAC; 3,4-dihydroxyphenylacetic acid; 3-MT; 3-methoxytyramine; DA; dopamine; DAT; dopamine
Increased striatal VMAT2 binding in mice after chronic administration of methcathinone and manganese
Keywords: Manganism; Ephedrone; Methcathinone; VMAT2; PET;
Effects of anesthetics on vesicular monoamine transporter type 2 binding to 18F-FP-(+)-DTBZ: a biodistribution study in rat brain
Keywords: VMAT2; Anesthesia; In vivo binding; Biodistribution; Rat brain;
JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death
Keywords: Parkinson's disease; Rotenone; JNK; Dopamine neuron; Microtubule; VMAT2;
Translational research for Parkinson׳s disease: The value of pre-clinical primate models
Keywords: PD; Parkinson׳s disease; SNpc; substantia nigra pars compacta; L-DOPA; Levodopa, 3,4-dihydroxyphenylalanine; 6OHDA; 6-hydroxydopamine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AADC; L-aromatic amino acid decarboxylase; TH; tyrosine hydroxylase
Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits
Keywords: DAT; dopamine transporter; PD; Parkinson's disease; DAT-tg; dopamine transporter over-expressing transgenic; DAT-KO; dopamine transporter knock-out; VMAT2; vesicular monoamine transporter 2; VMAT2-kd; vesicular monoamine transporter 2 knock-down; MPTP; 1-
Comparison of 99mTc-TRODAT-1 SPECT and 18 F-AV-133 PET imaging in healthy controls and Parkinson’s disease patients
Keywords: 18 F-AV-133; 99mTc-TRODAT-1; VMAT2; DAT; Parkinson's disease
Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons
Keywords: Dopamine; D2 autoreceptors; KATP channels; HCN channels; Brain slice; ACSF; artificial cerebrospinal fluid; ATP; adenosine triphosphate; DA; dopamine; DAT; dopamine transporter; GIRK; G protein-coupled inwardly rectifying potassium channels; HCN; hyperpol
Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats
Keywords: Methamphetamine; VMAT2; Dopamine; Self-administration;
Lsamp-/- mice display lower sensitivity to amphetamine and have elevated 5-HT turnover
Keywords: 3-MT; 3-methoxytyramine; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; HVA; homovanillic acid; LAMP; limbic system-associated membrane protein; Lsamp; limbic-system-ass
Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake
Keywords: Lobelane; Azetidine analogs; Methamphetamine abuse; VMAT2; [3H]DA uptake;
Vesicular Ca2+ mediates granule motion and exocytosis
Keywords: V-ATPase; vesicular H+-ATPase; VMAT2; vesicular monoamine transporter; LDCV; large dense core vesicles; Cgs; chromogranins; CgA; chromogranin A; CgB; chromogranin B; SgII; secretogranin type II; SERCA; sarcoplasmic reticulum calcium ATPase; CICR; Ca2+-ind
Regulatory effects of costunolide on dopamine metabolism-associated genes inhibit dopamine-induced apoptosis in human dopaminergic SH-SY5Y cells
Keywords: Costunolide; Dopamine; α-Synuclein; Nurr1; DAT; VMAT2;
Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells
Keywords: TH, tyrosine hydroxylase; DDC, L-DOPA decarboxylase; VMAT2, vesicular monoamine transporter 2; 3,4-DHP, 3,4-dihydroxy-l-phenylalanineDJ-1; VMAT2; Dopamine
A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport
Keywords: VMAT2; Slc18a2; Monoamine; Dopamine; Transporter;
Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates
Keywords: HPA; human protein atlas; IHC; immunohistochemistry; GLP-1R; glucagon-like peptide 1 receptor; PET; positron emission tomography; T1D; type 1 diabetes; T2D; type 2 diabetes; TMA; tissue microarray; VMAT2; vesicular monoamine transporter 2; Beta cell bioma
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
Keywords: Short hairpin RNA; Tyrosine hydroxylase; Adeno-associated virus; VMAT2; Transgenic mice;
Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse
Keywords: α-syn; α-synuclein; ASK1; Apoptosis signaling-regulating kinase 1; CMA; Chaperone-mediated autophagy; DAT; Dopamine transporter; ETC; Electron transport chain; iPS; Induced pluripotent stem; LAMP-2A; Lysosome-associated membrane protein 2A; LB; Lewy bod
Synuclein modulation of monoamine transporters
Keywords: α-Syn; α-synuclein; β-Syn; β-synuclein; γ-Syn; γ-synuclein; AD; Alzheimer's disease; CNS; central nervous system; DA; dopamine; DAT; dopamine transporter; DMI; desipramine; MAT; presynaptic plasma membrane monoamine transporters; NAC; non-Aβ comp
Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors
Keywords: Tetrabenazine enantiomers; Dihydrotetrabenazine stereoisomers; Resolution; Huntington’s chorea; VMAT2; Hyperkinetic disorders
Medial prefrontal cortical synapsin II knock-down induces behavioral abnormalities in the rat: Examining synapsin II in the pathophysiology of schizophrenia
Keywords: aCSF; artificial cerebral spinal fluid; ADON; antisense deoxyoligonucleotide; ANOVA; analysis of variance; APD; antipsychotic drug; cm; centimeter; DA; dopamine; dB; decibel; IP; intraperitoneally; MM; mismatch oligonucleotide; MPFC; medial prefrontal cor
Co-expression studies of the orphan carrier protein Slc10a4 and the vesicular carriers VAChT and VMAT2 in the rat central and peripheral nervous system
Keywords: Slc10a4; VAChT; VMAT2; synaptic vesicles; transportAsbt, apical sodium-dependent bile acid transporter; BAC, bacterial artificial chromosome; BSA, bovine serum albumin; ChAT, choline acetyltransferase; CHT1, high affinity choline transporter; CVF, crude v