دانلود مقالات ISI درباره کانال سدیم ولتاژ + ترجمه فارسی

Differential gene expression profiles of two excitable rat cell lines after over-expression of WT- and C121W-β1 sodium channel subunits

Keywords: کانال سدیم ولتاژ; CDS; coding sequence; eBFP; enhanced Blue Fluorescent Protein; GEFS+; generalized epilepsy with febrile seizure; NaCh; Na+ channels; RIN; RNA integrity number; WT; wild type; voltage-gated sodium channel; epilepsy; mRNA; DNA-microarray; gene expression;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Comparative evaluation of in vitro and in vivo high glucose-induced alterations in voltage-gated tetrodotoxin-resistant sodium channel: Effects attenuated by sodium channel blockers

Keywords: کانال سدیم ولتاژ; DRG; dorsal root ganglion; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HG; high glucose; INa; sodium current; NG; normal glucose; STZ; streptozotocin; TTX; tetrodotoxin; VGSC; voltage-gated sodium channel; diabetic neuropathy; dorsal root g

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Sudden Cardiac Death and Disorders of the QT Interval: Anesthetic Implications and Focus on Perioperative Management

Keywords: کانال سدیم ولتاژ; QT interval; long QT syndrome; short QT syndrome; torsades de pointes; magnesium; pacemaker; automated implanted cardiac defibrillator; transmural repolarization; cardiac ion channelopathy; Brugada syndrome; voltage-gated sodium channel; Bazett formula; b

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Proteomics; Post-translational modification; N-terminal acetylation; Arginine methylation; Heart failure;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Ala-7, His-10 and Arg-12 are crucial amino acids for activity of a synthetically engineered μ-conotoxin

Keywords: کانال سدیم ولتاژ; NaV-channel; voltage-gated sodium channel; CD; circular dichroism; (μ-)Conotoxin; Voltage-gated sodium channel; Midi R2; Circular dichroism; Cone snail; Peptidomimetics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Fentanyl produces an anti-hyperalgesic effect through the suppression of sodium channels in mice with painful diabetic neuropathy

Keywords: کانال سدیم ولتاژ; Fentanyl; Painful diabetic neuropathy; Voltage-gated sodium channel; Opioid receptor; Mouse;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Fine-tuning T cell receptor signaling to control T cell development

Keywords: کانال سدیم ولتاژ; T cell development; signaling; thymocyte; Themis; Tespa1; voltage-gated sodium channel; miR-181

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; NaV channel modulator; Marine alkaloid; Clathrodin; Pyrrole-2-aminoimidazole; 4-Phenyl-2-aminoimidazole; VGSC; voltage-gated sodium channel; NaV channel; voltage-gated sodium channel; TBTU; N,N,N′,N′-tetramethyl-O-(benzot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance

Keywords: کانال سدیم ولتاژ; Scn8a; Nav1.6; Scn1a; Nav1.1; GEFS+; Dravet syndrome; Voltage-gated sodium channel; Lentivirus; Cre recombinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The evolution of insecticide resistance in the peach potato aphid, Myzus persicae

Keywords: کانال سدیم ولتاژ; Myzus persicae; Esterase; P450; Acetylcholinesterase; Nicotinic acetylcholine receptor; Voltage-gated sodium channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena

Keywords: کانال سدیم ولتاژ; HWTX-XVI; Tarantula toxin; N-type calcium channels; Dorsal root ganglia; Rat vas deferens; Pain model; Analgesic action; HWTX; Huwentoxin; ICK; inhibitor cystine knot; Cav channel; voltage-gated calcium channel; Nav channel; voltage-gated sodium channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice

Keywords: کانال سدیم ولتاژ; Seizures; Epilepsy; Mouse model; Voltage-gated sodium channel; Electrophysiology; Modifier genes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

NaV1.5 and Regulatory β Subunits in Cardiac Sodium Channelopathies

Keywords: کانال سدیم ولتاژ; Arrhythmia; β Subunit; Voltage-gated sodium channel; Animal model;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and evaluation of a 125I-labeled iminodihydroquinoline-derived tracer for imaging of voltage-gated sodium channels

Keywords: کانال سدیم ولتاژ; SPECT; Voltage-gated sodium channel; WIN17317-3; Iodine-125; Imaging;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Potency optimization of Huwentoxin-IV on hNav1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena

Keywords: کانال سدیم ولتاژ; ACF; animal-component free; BSA; bovine serum albumin; CaCl2; calcium chloride; CD; circular dichroism spectroscopy; CHO; Chinese hamster ovary; CNS; central nervous system; CO2; carbon dioxide; CsF; cesium fluoride; CsOH; cesium hydroxide; DIC; diisoprop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Allodynia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

FGF14 localization and organization of the axon initial segment

Keywords: کانال سدیم ولتاژ; AIS; axon initial segment; FGF14; fibroblast growth factor 14; iFGF; intracellular fibroblast growth factor; Nav; voltage gated sodium channel; Purkinje neuron; Axon initial segment; AIS; iFGF; FGF14; Voltage-gated sodium channel; Scn1a; Scn8a; Ankyrin G;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges

Keywords: کانال سدیم ولتاژ; Agelas; Marine; Clathrodin; Sodium channel modulator; DMF; N,N-dimethylformamide; DRG; dorsal root ganglia; TBTU; O-benzotriazol-1-yl-N,N,N′,N′-tetramethyluronium tetrafluoroborate; THF; tetrahydrofuran; VGSC; voltage-gated sodium channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Voltage-gated sodium channels contribute to the b-wave of the rodent electroretinogram by mediating input to rod bipolar cell GABAc receptors

Keywords: کانال سدیم ولتاژ; retina; electroretinogram; tetrodotoxin; GABAc receptors; sodium channels; bipolar cells; amacrine cells; retinal circuits; CNQX; 6-Cyano-7-nitroquinoxaline-2,3-dion; ERG; electroretinogram; GABA; gamma-aminobutyric acid; Nav; voltage-gated sodium channel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The up-regulation of voltage-gated sodium channels subtypes coincides with an increased sodium current in hippocampal neuronal culture model

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Subtypes; Sodium current; Epilepsy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Abnormal changes in voltage-gated sodium channels NaV1.1, NaV1.2, NaV1.3, NaV1.6 and in calmodulin/calmodulin-dependent protein kinase II, within the brains of spontaneously epileptic rats and tremor rats

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Subtype; Calmodulin; Calmodulin-dependent protein kinase II; Genetic epilepsy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Neurotoxin; Spider-venom peptide; Pore blocker; Gating modifier; Inhibitor cystine knot

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Voltage-gated sodium channel activity promotes prostate cancer metastasis in vivo

Keywords: کانال سدیم ولتاژ; Prostate cancer; Metastasis; Dunning cell; Mat-LyLu; Voltage-gated sodium channel; Tetrodotoxin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Short communicationAcute encephalopathy with a novel point mutation in the SCN2A gene

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Missense mutation; Acute encephalopathy;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Inheritance and stability of sodium channel mutations associated with permethrin knockdown resistance in Aedes aegypti

Keywords: کانال سدیم ولتاژ; Amino acid substitutions; Voltage-gated sodium channel; Knockdown resistance; Aedes aegypti; Degree of dominance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Transmembrane and extramembrane contributions to membrane protein thermal stability: Studies with the NaChBac sodium channel

Keywords: کانال سدیم ولتاژ; CD; circular dichroism; Cymal-5; 5-cyclohexyl-1-pentyl-β-D maltoside; EM; extramembrane; FL; full-length (native) NaChBac; NaChBac; voltage-gated sodium channel from B. halodurans; SDS; sodium dodecyl sulfate; SRCD; synchrotron radiation circular dichroi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

BACE1 in Alzheimer's disease

Keywords: کانال سدیم ولتاژ; Aβ; β-amyloid; ACDL; acid-cluster dileucine motif; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease domain protein; AICD; amyloid precursor protein intracellular domain; APLP; amyloid precursor-like protein; ApoE; apolipoprotein E; APP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitory effect of the recombinant Phoneutria nigriventer Tx1 toxin on voltage-gated sodium channels

Keywords: کانال سدیم ولتاژ; Sodium channel; Sodium current; Spider toxin; Peptide toxin; Sodium channel inhibition; Isoform selectivity; PnTx1; Phoneutria nigriventer toxin 1; rPnTx1; recombinant PnTx1; KIIIA; μ-conotoxin KIIIA; GIIIA; μ-conotoxin GIIIA; SIIIA; μ-conotoxin SIIIA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels

Keywords: کانال سدیم ولتاژ; β-Scorpion toxin; Centruroides; Patch clamp; Three-dimensional models; Voltage-gated sodium channel; HPLC; high performance liquid chromatography; HEK; human embryonic kidney; Nav; Na+-channel; TTX; tetrodotoxin; VGSCs; voltage-gated sodium channels;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Spider-venom peptides that target voltage-gated sodium channels: Pharmacological tools and potential therapeutic leads

Keywords: کانال سدیم ولتاژ; Spider venom; Peptide; Inhibitor cystine knot; Voltage-gated sodium channel; Therapeutic; Analgesic; Insecticide; ArachnoServer; NaV1.7;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Sustained increase in the excitability of myelinated peripheral axons to depolarizing current is mediated by Nav1.6

Keywords: کانال سدیم ولتاژ; Axonal excitability; Voltage-gated sodium channel; Scn8a; Persistent sodium current; Neurography; Threshold tracking;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

A naturally-occurring carboxyl-terminally truncated α-scorpion toxin is a blocker of sodium channels

Keywords: کانال سدیم ولتاژ; 3′-UTR; 3′-untranslational region; CD; circular dichroism; DRG; dorsal root ganglia; IC50; 50% inhibitory concentration; VGPC; voltage-gated potassium channel; MALDI-TOF MS; matrix-assisted laser desorption ionization time-of-flight mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Actions of tefluthrin on rat Nav1.7 voltage-gated sodium channels expressed in Xenopus oocytes

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Nav1.7 isoform; Pyrethroid; Tefluthrin; Peripheral nervous system; Dorsal root ganglion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; μ-Conotoxin; Pain; Receptor site-1; Channel block

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Electrical injury alters ion channel expression levels and electrophysiological properties in rabbit dorsal root ganglia neurons

Keywords: کانال سدیم ولتاژ; Voltage-gated potassium channel; Voltage-gated sodium channel; Electrical injury; Dorsal root ganglia; Voltage-gated potassium current; Voltage-gated sodium current

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus

Keywords: کانال سدیم ولتاژ; Tityus serrulatus; Scorpion venom; Potassium channel; KTx; Kv channel; voltage-gated potassium channel; NaV channel; voltage-gated sodium channel; KTxs; voltage-gated potassium channel toxins; Tsv; Tityus serrulatus venom;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Bilayer lipid membranes supported on Teflon filters: A functional environment for ion channels

Keywords: کانال سدیم ولتاژ; Polytetrafluoroethylene (PTFE); Teflon; Bilayer lipid membrane; Impedance spectroscopy; Voltage-gated sodium channel; Biosensor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The developmental changes of Nav1.1 and Nav1.2 expression in the human hippocampus and temporal lobe

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Nav1.1; Nav1.2; Brain development; Double-staining immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Differential resistance of insect sodium channels with kdr mutations to deltamethrin, permethrin and DDT

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Pyrethroid; DDT; Insecticide resistance; Xenopus oocyte; Voltage clamp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Differential state-dependent modification of rat Nav1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Nav1.6 isoform; Pyrethroid; Deltamethrin; Tefluthrin; HEK293 cells;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers

Keywords: کانال سدیم ولتاژ; Neuropathic pain; Voltage-gated sodium channel; Nav1.7 blockers; Biaryl oxazoles; Biaryl imidazoles; Biaryl thiazoles

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Alzheimer's secretases regulate voltage-gated sodium channels

Keywords: کانال سدیم ولتاژ; Alzheimer's disease; BACE1; β-Secretase; Presenilin; γ-Secretase; Voltage-gated sodium channel; Sodium channel β2-subnit;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Nav1.6 sodium channels

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Nav1.6 isoform; Pyrethroid; S-Bioallethrin; Deltamethrin; Tefluthrin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The C-terminal coiled-coil of the bacterial voltage-gated sodium channel NaChBac is not essential for tetramer formation, but stabilizes subunit-to-subunit interactions

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; NaChBac; Subunit assembly; Coiled-coil

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: Activity-dependent positive feedback and cellular migration

Keywords: کانال سدیم ولتاژ; Breast cancer; Metastasis; Voltage-gated sodium channel; Neonatal Nav1.5; Activity-dependent regulation; Feedback; Protein kinase A; Forskolin; KT5720; Tetrodotoxin; Migration; Invasion

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels

Keywords: کانال سدیم ولتاژ; BmK I; Spontaneous pain; Thermal pain hypersensitivity; Mirror-image mechanical pain; Voltage-gated sodium channel; Capsaicin-sensitive primary afferent neuron

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

A novel amino acid substitution in a voltage-gated sodium channel is associated with knockdown resistance to permethrin in Aedes aegypti

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Aedes aegypti; Knockdown resistance; Synergistic effect; RNA editing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular characterization of a sodium channel gene from the Silkworm Bombyx mori

Keywords: کانال سدیم ولتاژ; Para; Voltage-gated sodium channel; Alternative splicing; Bombyx mori

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Single channel study of deltamethrin interactions with wild-type and mutated rat NaV1.2 sodium channels expressed in Xenopus oocytes

Keywords: کانال سدیم ولتاژ; Voltage-gated sodium channel; Pyrethroid insecticides; Patch-clamp; Single channel recording

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao

Keywords: کانال سدیم ولتاژ; JZTX-IX; Tarantula toxin; Voltage-gated sodium channel; Voltage-gated potassium channel; Closed configurationJZTX, Jingzhaotoxin; ICK, inhibitor cystine knot; Nav channel, voltage-gated sodium channel; DRG, dorsal root ganglion; TTX, tetrodotoxin; TTX-R,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه