FDG PET is superior to CT in the prediction of viable tumour in post-chemotherapy seminoma residuals

In post-chemotherapy seminoma residuals, a positive PET is highly predictive for the presence of viable tumour. The specificity of PET is significantly higher than that of CT when using a ≥3 cm cut-off. A negative PET scan is excellent for the exclusion of disease in lesions ≥3 cm, with a somewhat higher sensitivity than CT (n.s.). PET can contribute to the management of residual seminoma lesions, especially in terms of avoiding unnecessary additional treatment for patients with lesions ≥3 cm.