کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10134887 1645649 2018 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Green and efficient extraction of four bioactive flavonoids from Pollen Typhae by ultrasound-assisted deep eutectic solvents extraction
ترجمه فارسی عنوان
استخراج سبز و کارآمد از 4 فلاونوئیدهای فعال زیست محیطی از تیپهای گرده با استفاده از استخراج حلال های عمیق عمیق با کمک فراکسیون
کلمات کلیدی
حلال های عمیق یوتکتیک، استخراج سبز، فلاونوئیدها، گرده گیاهان
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Recently, deep eutectic solvents (DESs) have been recognized as a novel class of sustainable solvents to replace common organic solvents. In this study, a highly and efficient extraction technique for determination of four bioactive flavonoids from Pollen Typhae using a combination of ultrasound-assisted extraction and natural deep eutectic solvents (NADESs) was developed. A series of DESs containing various hydrogen bond acceptors combined with different hydrogen bond donors were synthesized and screened for high extraction efficiencies based on the flavonoids extraction yields. The extraction conditions including composition of DES, water content in DES, liquid-solid ratio, and extraction time were statistically optimized by single-factor experiment. As a result, DES composed of choline chloride and 1,2-propanediol (ChPri) at 1:4 M ratio, 30% of aqueous solution, 50:1 mg mL−1 for solid-liquid ratio, and 35 min for extraction time were selected as the most effective process for extraction of flavonoids in Pollen Typhae. Under the optimal conditions, the target compounds recoveries were in the range of 86.87%-98.89%. Meanwhile, DESs showed greater extraction efficiency for extraction of quercetin, naringenin, kaempferol and isorhamnetin from Pollen Typhae comparing with conventional solvents such as methanol and 75% of aqueous ethanol. Comparing DESs to the conventional organic solvents, in addition to their reduced environmental impacts, they proved to provide higher extraction efficiency for flavonoids, and therefore have a great potential as possible alternatives to those organic solvents in extraction of Chinese herbal medicines.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 161, 30 November 2018, Pages 246-253
نویسندگان
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