کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10160657 | 247 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An unstructured model for the diauxic growth of Penicillium camembertii on glucose and arginine
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: An unstructured model for the diauxic growth of Penicillium camembertii on glucose and arginine An unstructured model for the diauxic growth of Penicillium camembertii on glucose and arginine](/preview/png/10160657.png)
چکیده انگلیسی
Penicillium camembertii on glucose and arginine exhibited diauxic behaviour. Glucose was first assimilated and then, after its depletion, arginine was used as a carbon source in addition to a nitrogen source. A simple unstructured model was developed to describe the system. The consumption kinetics of both carbon substrates were described using a modified Verlhust model, without involving the key enzyme responsible for the degradation of the second carbon substrate, arginine. Growth kinetic was deduced from the sequential consumption of both carbon substrates, since biomass on carbon substrate yields were found to be constants. Major products, carbon dioxide and ammonium, resulted from both biosynthesis and viable cell maintenance, and were therefore assumed to be partially linked to growth. An additional term was also added in the production model to account for cessation of production when carbon became limiting, namely after exhaustion of the second carbon source, arginine. For both products, integration of production rate allowed the determination of calculated production kinetics, as well as the respective parts of growth- and non-growth-associated production. This determination showed that ammonium, resulting from arginine deamination, was mainly produced by a growth-associated mechanism; while, at the end of culture, similar contributions of both mechanisms were found for CO2 production.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical Engineering Journal - Volume 24, Issue 2, June 2005, Pages 125-133
Journal: Biochemical Engineering Journal - Volume 24, Issue 2, June 2005, Pages 125-133
نویسندگان
Abdeltif Amrane, Lydia Adour, Catherine Couriol,