کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10165490 | 1180236 | 2016 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fundamental Concepts Regarding Testosterone Deficiency and Treatment
ترجمه فارسی عنوان
مفاهیم پایه در مورد کمبود تستوسترون و درمان
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کلمات کلیدی
EMARCTSHBGFDAPCA - PCARandomized controlled trial - آزمایش تصادفی کنترل شدهMyocardial infarction - آنفارکتوس میوکاردEuropean Medicines agency - آژانس دارویی اروپاtestosterone - تستوسترونFood and Drug Administration - سازمان غذا و داروProstate cancer - سرطان پروستاتbody mass index - شاخص توده بدنBMI - شاخص توده بدنیcardiovascular - قلبی عروقیsex hormone–binding globulin - هورمون جنسی مرتبط گلوبولینTestosterone deficiency - کمبود تستوسترون
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
To address widespread concerns regarding the medical condition of testosterone (T) deficiency (TD) (male hypogonadism) and its treatment with T therapy, an international expert consensus conference was convened in Prague, Czech Republic, on October 1, 2015. Experts included a broad range of medical specialties including urology, endocrinology, diabetology, internal medicine, and basic science research. A representative from the European Medicines Agency participated in a nonvoting capacity. Nine resolutions were debated, with unanimous approval: (1) TD is a well-established, clinically significant medical condition that negatively affects male sexuality, reproduction, general health, and quality of life; (2) symptoms and signs of TD occur as a result of low levels of T and may benefit from treatment regardless of whether there is an identified underlying etiology; (3) TD is a global public health concern; (4) T therapy for men with TD is effective, rational, and evidence based; (5) there is no T concentration threshold that reliably distinguishes those who will respond to treatment from those who will not; (6) there is no scientific basis for any age-specific recommendations against the use of T therapy in men; (7) the evidence does not support increased risks of cardiovascular events with T therapy; (8) the evidence does not support increased risk of prostate cancer with T therapy; and (9) the evidence supports a major research initiative to explore possible benefits of T therapy for cardiometabolic disease, including diabetes. These resolutions may be considered points of agreement by a broad range of experts based on the best available scientific evidence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 91, Issue 7, July 2016, Pages 881-896
Journal: Mayo Clinic Proceedings - Volume 91, Issue 7, July 2016, Pages 881-896
نویسندگان
Abraham (Chairman), Michael (Cochairman), Abdulmaged M. (writing group), Anthony W. (writing group), T. Hugh (writing group), Mario (writing group), Stefan MD, Antonio MD, Juliana C.N. MD, Adrian S. MD, Geoffrey I. MD, Wayne J. MD, Peter MD, Bruno MD,