Regulacje molekularne procesu niszczenia kości w zapaleniu perlakowym ucha

Bone destruction in chronic otitis media with cholesteatoma is a common process dependent on osteoclast activating factors. OPG/RANKL/RANK system and TNF-α play a key role in the process of osteolysis in otitis media with cholesteatoma. We found no positive correlation between bone destruction advancement and the level of examinated proteins.