کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
102176 161309 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tramadol deaths in Northern Ireland: A review of cases from 1996 to 2012
ترجمه فارسی عنوان
مرگ ترامادول در ایرلند شمالی: بازبینی پرونده های سال های 1996 تا 2012
کلمات کلیدی
ترامادول، مصرف بیش از حد
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
چکیده انگلیسی

In the UK tramadol is a frequently prescribed opioid analgesic which is becoming increasingly popular as a drug of misuse. Its use varies worldwide and in the last decade it has been upgraded to a controlled substance in several countries, due to an increased number of deaths associated with its use.A review of all deaths associated with tramadol in Northern Ireland was performed and this highlighted 127 cases from 1996 to the end of 2012. A 10% increase in deaths due to tramadol was noted. In 2001 tramadol deaths represented 9% of all drug misuse deaths rising to 40% in 2011. The majority of the deaths occurred in males (62%), with a median age of 41 years, living in the Belfast city area (36%). Tramadol fatalities were found in combination with other drugs/medicines (49%), alcohol (36%) or alone (23%). Most of those who died did not reach hospital, with only 2% presenting with multi-organ or acute liver failure. In just over half of the deaths tramadol had not been prescribed by a medical practitioner (53%). Depression, addiction and seizures were recognised risk factors.An increase in awareness of tramadol toxicity is needed amongst the public and doctors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Forensic and Legal Medicine - Volume 23, March 2014, Pages 32–36
نویسندگان
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